List of works - Yung-Jen Chuang

A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition.

scientific article published on 3 May 2015

A Novel Molecular Signature Identified by Systems Genetics Approach Predicts Prognosis in Oral Squamous Cell Carcinoma ⬇️

scientific article published on August 11, 2011

A Sketch of the Taiwan Zebrafish Core Facility

scientific article published on 06 June 2016

A genetic algorithm-based boolean delay model of intracellular signal transduction in inflammation ⬇️

scientific article published on February 15, 2011

Adenylate kinase-4 is a marker of poor clinical outcomes that promotes metastasis of lung cancer by downregulating the transcription factor ATF3.

scientific article

Analysis of DNA Damage Responses After Boric Acid-mediated Boron Neutron Capture Therapy in Hepatocellular Carcinoma

scientific article published on 01 December 2019

Antiangiogenic antithrombin down-regulates the expression of the proangiogenic heparan sulfate proteoglycan, perlecan, in endothelial cells

scientific article published on 16 October 2003

Antiangiogenic antithrombin induces global changes in the gene expression profile of endothelial cells.

scientific article

Baculovirus vectors for antiangiogenesis-based cancer gene therapy ⬇️

scientific article published on June 24, 2011

Biomarker discovery for neuroendocrine cervical cancer

scientific article

Combined use of MS-222 (tricaine) and isoflurane extends anesthesia time and minimizes cardiac rhythm side effects in adult zebrafish.

scientific article published on September 2010

Convergence of physical and chemical signaling in the modulation of vascular smooth muscle cell cycle and proliferation by fibrillar collagen-regulated P66Shc.

scientific article

Cordycepin Suppresses Endothelial Cell Proliferation, Migration, Angiogenesis, and Tumor Growth by Regulating Focal Adhesion Kinase and p53

scientific article published on 01 February 2019

Cysteine-rich protein 2 alters p130Cas localization and inhibits vascular smooth muscle cell migration

scientific article published on 23 August 2013

Development of a rapid and economic in vivo electrocardiogram platform for cardiovascular drug assay and electrophysiology research in adult zebrafish

scientific article published in Scientific Reports

Direct-growth carbon nanotubes on 3D structural microelectrodes for electrophysiological recording.

scientific article published on 20 November 2015

Diverse Hap43-Independent Functions of the Candida albicans CCAAT-Binding Complex ⬇️

scientific article published on March 29, 2013

Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFalpha-induced inflammatory responses

scientific article

Dynamic transcript profiling of Candida albicans infection in zebrafish: a pathogen-host interaction study

scientific article

Effect of Tumor Microenvironment on Selective Uptake of Boric Acid in HepG2 Human Hepatoma Cells.

scientific article published in November 2017

Effects of an injectable functionalized self-assembling nanopeptide hydrogel on angiogenesis and neurogenesis for regeneration of the central nervous system

scientific article published on 19 October 2017

Essential functional modules for pathogenic and defensive mechanisms in Candida albicans infections

scientific article published on 18 March 2014

Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes

scientific article published on 01 June 2018

Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation

scientific article published on 01 January 2008

Generation of a Tg(cyp1a-12DRE:EGFP) transgenic zebrafish line as a rapid in vivo model for detecting dioxin-like compounds

scientific article published on 30 October 2018

Heparin activates antithrombin anticoagulant function by generating new interaction sites (exosites) for blood clotting proteinases.

scientific article

Heparin and calcium ions dramatically enhance antithrombin reactivity with factor IXa by generating new interaction exosites.

scientific article

Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin

scientific article

Identification of infection- and defense-related genes via a dynamic host-pathogen interaction network using a Candida albicans-zebrafish infection model.

scientific article published on 13 February 2013

Importance of the P2 glycine of antithrombin in target proteinase specificity, heparin activation, and the efficiency of proteinase trapping as revealed by a P2 Gly --> Pro mutation.

scientific article published on October 1999

Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway.

scientific article published on 02 August 2016

NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish.

scientific article

PI3K inhibitor enhances the cytotoxic response to etoposide and cisplatin in a newly established neuroendocrine cervical carcinoma cell line.

scientific article

PRSS23 is essential for the Snail-dependent endothelial-to-mesenchymal transition during valvulogenesis in zebrafish.

scientific article published on 4 December 2012

Proteomic investigating the cooperative lethal effect of EGFR and MDM2 inhibitors on ovarian carcinoma.

scientific article published on 12 April 2018

Robust model matching control of immune systems under environmental disturbances: dynamic game approach.

scientific article

Robustness analysis on interspecies interaction network for iron and glucose competition between Candida albicans and zebrafish during infection

scientific article

Serine protease PRSS23 is upregulated by estrogen receptor α and associated with proliferation of breast cancer cells

scientific article

Significance of heparin binding to basic residues in homologous to the amino terminus of hepatoma-derived growth factor and related proteins.

scientific article published on 4 January 2012

Soluble THSD7A is an N-glycoprotein that promotes endothelial cell migration and tube formation in angiogenesis

scientific article

Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions.

scientific article

Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications

scientific article published on 26 December 2020

The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling

scientific article published on 07 January 2020

The role of TGF-β signaling and apoptosis in innate and adaptive immunity in zebrafish: a systems biology approach.

scientific article

Therapeutic Efficacy and Radiobiological Effects of Boric Acid-mediated BNCT in a VX2 Multifocal Liver Tumor-bearing Rabbit Model

scientific article published on 01 October 2019

Thrombospondin type I domain containing 7A (THSD7A) mediates endothelial cell migration and tube formation

scientific article

Treatment of Glucocorticoids Inhibited Early Immune Responses and Impaired Cardiac Repair in Adult Zebrafish.

scientific article

Tumor-induced endothelial cell apoptosis: roles of NAD(P)H oxidase-derived reactive oxygen species

scientific article published on 01 July 2011

Uncovering the regeneration strategies of zebrafish organs: a comprehensive systems biology study on heart, cerebellum, fin, and retina regeneration.

scientific article published on 19 March 2018

Zebrafish Thsd7a is a neural protein required for angiogenic patterning during development ⬇️

scientific article published on April 25, 2011

Zebrafish as a model host for Candida albicans infection.

scientific article

Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column

scientific article published on 03 May 2018

Zebrafish model of photochemical thrombosis for translational research and thrombolytic screening in vivo

scientific article

List of works by Yung-Jen Chuang

A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition.

A Novel Molecular Signature Identified by Systems Genetics Approach Predicts Prognosis in Oral Squamous Cell Carcinoma ⬇️

A Sketch of the Taiwan Zebrafish Core Facility

A genetic algorithm-based boolean delay model of intracellular signal transduction in inflammation ⬇️

Adenylate kinase-4 is a marker of poor clinical outcomes that promotes metastasis of lung cancer by downregulating the transcription factor ATF3.

Analysis of DNA Damage Responses After Boric Acid-mediated Boron Neutron Capture Therapy in Hepatocellular Carcinoma

Antiangiogenic antithrombin down-regulates the expression of the proangiogenic heparan sulfate proteoglycan, perlecan, in endothelial cells

Antiangiogenic antithrombin induces global changes in the gene expression profile of endothelial cells.

Baculovirus vectors for antiangiogenesis-based cancer gene therapy ⬇️

Biomarker discovery for neuroendocrine cervical cancer

Combined use of MS-222 (tricaine) and isoflurane extends anesthesia time and minimizes cardiac rhythm side effects in adult zebrafish.

Convergence of physical and chemical signaling in the modulation of vascular smooth muscle cell cycle and proliferation by fibrillar collagen-regulated P66Shc.

Cordycepin Suppresses Endothelial Cell Proliferation, Migration, Angiogenesis, and Tumor Growth by Regulating Focal Adhesion Kinase and p53

Cysteine-rich protein 2 alters p130Cas localization and inhibits vascular smooth muscle cell migration

Development of a rapid and economic in vivo electrocardiogram platform for cardiovascular drug assay and electrophysiology research in adult zebrafish

Direct-growth carbon nanotubes on 3D structural microelectrodes for electrophysiological recording.

Diverse Hap43-Independent Functions of the Candida albicans CCAAT-Binding Complex ⬇️

Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFalpha-induced inflammatory responses

Dynamic transcript profiling of Candida albicans infection in zebrafish: a pathogen-host interaction study

Effect of Tumor Microenvironment on Selective Uptake of Boric Acid in HepG2 Human Hepatoma Cells.

Effects of an injectable functionalized self-assembling nanopeptide hydrogel on angiogenesis and neurogenesis for regeneration of the central nervous system

Essential functional modules for pathogenic and defensive mechanisms in Candida albicans infections

Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes

Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation

Generation of a Tg(cyp1a-12DRE:EGFP) transgenic zebrafish line as a rapid in vivo model for detecting dioxin-like compounds

Heparin activates antithrombin anticoagulant function by generating new interaction sites (exosites) for blood clotting proteinases.

Heparin and calcium ions dramatically enhance antithrombin reactivity with factor IXa by generating new interaction exosites.

Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin

Identification of infection- and defense-related genes via a dynamic host-pathogen interaction network using a Candida albicans-zebrafish infection model.

Importance of the P2 glycine of antithrombin in target proteinase specificity, heparin activation, and the efficiency of proteinase trapping as revealed by a P2 Gly --> Pro mutation.

Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway.

NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish.

PI3K inhibitor enhances the cytotoxic response to etoposide and cisplatin in a newly established neuroendocrine cervical carcinoma cell line.

PRSS23 is essential for the Snail-dependent endothelial-to-mesenchymal transition during valvulogenesis in zebrafish.

Proteomic investigating the cooperative lethal effect of EGFR and MDM2 inhibitors on ovarian carcinoma.

Robust model matching control of immune systems under environmental disturbances: dynamic game approach.

Robustness analysis on interspecies interaction network for iron and glucose competition between Candida albicans and zebrafish during infection

Serine protease PRSS23 is upregulated by estrogen receptor α and associated with proliferation of breast cancer cells

Significance of heparin binding to basic residues in homologous to the amino terminus of hepatoma-derived growth factor and related proteins.

Soluble THSD7A is an N-glycoprotein that promotes endothelial cell migration and tube formation in angiogenesis

Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions.

Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications

The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling

The role of TGF-β signaling and apoptosis in innate and adaptive immunity in zebrafish: a systems biology approach.

Therapeutic Efficacy and Radiobiological Effects of Boric Acid-mediated BNCT in a VX2 Multifocal Liver Tumor-bearing Rabbit Model

Thrombospondin type I domain containing 7A (THSD7A) mediates endothelial cell migration and tube formation

Treatment of Glucocorticoids Inhibited Early Immune Responses and Impaired Cardiac Repair in Adult Zebrafish.

Tumor-induced endothelial cell apoptosis: roles of NAD(P)H oxidase-derived reactive oxygen species

Uncovering the regeneration strategies of zebrafish organs: a comprehensive systems biology study on heart, cerebellum, fin, and retina regeneration.

Zebrafish Thsd7a is a neural protein required for angiogenic patterning during development ⬇️

Zebrafish as a model host for Candida albicans infection.

Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column

Zebrafish model of photochemical thrombosis for translational research and thrombolytic screening in vivo