List of works - Christoph J Binder

Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury

scientific article published in April 2008

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

scientific journal article

Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity

scientific article published on January 2011

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

scientific article published on 5 October 2011

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

scientific article published on 13 April 2009

Generation and biological activities of oxidized phospholipids

scientific article

B cell depletion reduces the development of atherosclerosis in mice

scientific article

B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction

scientific article

Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory

scientific article

A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma

scientific article

Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis

article by Yvonne Döring et al published 3 April 2012 in Circulation

CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice

scientific article published on July 2011

Disease-specific molecular events in cortical multiple sclerosis lesions.

scientific article published on 17 May 2013

B Cells and Humoral Immunity in Atherosclerosis

scientific article published on May 23, 2014

Adaptive immunity in atherogenesis: new insights and therapeutic approaches

scientific article

Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

scientific article

The role of innate immunity in atherogenesis

scientific article published on 22 December 2008

Naturally occurring auto-antibodies in homeostasis and disease

scientific article published on 04 December 2008

The innate immune response to products of phospholipid peroxidation

scientific article

Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice.

scientific article

LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease

scientific article

Natural antibodies and the autoimmunity of atherosclerosis.

scientific article

BAFF receptor deficiency reduces the development of atherosclerosis in mice--brief report

scientific article published on 15 March 2012

Glomerular overproduction of oxygen radicals in Mpv17 gene-inactivated mice causes podocyte foot process flattening and proteinuria: A model of steroid-resistant nephrosis sensitive to radical scavenger therapy.

scientific article published on April 1999

Oxidized low density lipoprotein and innate immune receptors

scientific article published on October 1, 2003

Natural IgM antibodies against oxidation-specific epitopes.

scientific article published on May 2010

Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells

scientific article

Immunological responses to oxidized LDL.

scientific article

Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies

scientific article

Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.

scientific article published on 13 March 2014

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

scientific article published in Nature

Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice

scientific article

Responsiveness of B cells is regulated by the hinge region of IgD.

scientific article

A diet-induced hypercholesterolemic murine model to study atherogenesis without obesity and metabolic syndrome

scientific article published on 25 January 2007

Targeting B cells in atherosclerosis: closing the gap from bench to bedside

scientific article

Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL

scientific article

Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation

scientific article

Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice

scientific article published on 24 March 2014

Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis.

scientific article published on 21 May 2012

Plasma interleukin-5 levels are related to antibodies binding to oxidized low-density lipoprotein and to decreased subclinical atherosclerosis.

scientific article

4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E‐null mice

scientific article published on September 27, 2010

Siglec-G regulates B1 cell survival and selection

scientific article published on 20 August 2010

Naturally Occurring IgM Antibodies to Oxidation-Specific Epitopes

scientific article published on 01 January 2012

Group X secreted phospholipase A2 limits the development of atherosclerosis in LDL receptor-null mice.

scientific article published on 24 January 2013

ApoE attenuates unresolvable inflammation by complex formation with activated C1q

scientific article published on 28 January 2019

Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease

scientific article

Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine

scientific article

CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies

scientific article

B-1 cell immunoglobulin directed against oxidation-specific epitopes.

scientific article published on January 2012

The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model

scientific article

List of works by Christoph J Binder

Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

Generation and biological activities of oxidized phospholipids

B cell depletion reduces the development of atherosclerosis in mice

B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction

Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory

A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma

Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis

CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice

Disease-specific molecular events in cortical multiple sclerosis lesions.

B Cells and Humoral Immunity in Atherosclerosis

Adaptive immunity in atherogenesis: new insights and therapeutic approaches

Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

The role of innate immunity in atherogenesis

Naturally occurring auto-antibodies in homeostasis and disease

The innate immune response to products of phospholipid peroxidation

Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice.

LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease

Natural antibodies and the autoimmunity of atherosclerosis.

BAFF receptor deficiency reduces the development of atherosclerosis in mice--brief report

Glomerular overproduction of oxygen radicals in Mpv17 gene-inactivated mice causes podocyte foot process flattening and proteinuria: A model of steroid-resistant nephrosis sensitive to radical scavenger therapy.

Oxidized low density lipoprotein and innate immune receptors

Natural IgM antibodies against oxidation-specific epitopes.

Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells

Immunological responses to oxidized LDL.

Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies

Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice

Responsiveness of B cells is regulated by the hinge region of IgD.

A diet-induced hypercholesterolemic murine model to study atherogenesis without obesity and metabolic syndrome

Targeting B cells in atherosclerosis: closing the gap from bench to bedside

Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL

Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation

Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice

Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis.

Plasma interleukin-5 levels are related to antibodies binding to oxidized low-density lipoprotein and to decreased subclinical atherosclerosis.

4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E‐null mice

Siglec-G regulates B1 cell survival and selection

Naturally Occurring IgM Antibodies to Oxidation-Specific Epitopes

Group X secreted phospholipase A2 limits the development of atherosclerosis in LDL receptor-null mice.

ApoE attenuates unresolvable inflammation by complex formation with activated C1q

Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease

Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine

CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies

B-1 cell immunoglobulin directed against oxidation-specific epitopes.

The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model