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List of works by William A. McEwan

AAA ATPase p97/VCP is essential for TRIM21-mediated virus neutralization.

scientific article

Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

scientific article

Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation.

scientific article published on 03 January 2017

Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

scientific article published on 28 May 2020

Diverse HIV viruses are targeted by a conformationally dynamic antiviral

scientific article

Genetically divergent strains of feline immunodeficiency virus from the domestic cat (Felis catus) and the African lion (Panthera leo) share usage of CD134 and CXCR4 as entry receptors.

scientific article published on 20 August 2008

Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.

scientific article

IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis

article

Intracellular antibody immunity

scientific article published on 11 April 2014

Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.

scientific article published on 3 March 2013

Intracellular antibody-mediated immunity and the role of TRIM21

scientific article published on 29 August 2011

Intracellular sensing of complement C3 activates cell autonomous immunity.

scientific article

Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells

scientific article published on 22 June 2023

Potent lentiviral restriction by a synthetic feline TRIM5 cyclophilin A fusion.

scientific article published on 16 June 2010

Regulation of Virus Neutralization and the Persistent Fraction by TRIM21

scientific article published on May 30, 2012

Restriction of the felid lentiviruses by a synthetic feline TRIM5-CypA fusion.

scientific article published on 12 June 2011

TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus

scientific article published on 27 October 2015

TRIM21-dependent intracellular antibody neutralization of virus infection.

scientific article

Target-induced clustering activates Trim-Away of pathogens and proteins

scientific article published on 25 February 2021

The lingering effects of an artificial blind spot

scientific article

Translocalized IgA mediates neutralization and stimulates innate immunity inside infected cells

scientific article

Truncation of TRIM5 in the Feliformia explains the absence of retroviral restriction in cells of the domestic cat

scientific article published on 03 June 2009