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List of works by Kellie R. Machlus

Abnormal megakaryopoiesis and platelet function in cyclooxygenase-2-deficient mice

scientific article

Anticoagulation inhibits tumor cell-mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response.

scientific article published on 24 September 2013

Aspirin inhibits platelets from reprogramming breast tumor cells and promoting metastasis

scientific article published on 01 January 2019

Blood and Bone: The quarantine chronicles

scientific article published on 28 June 2020

CCL5 derived from platelets increases megakaryocyte proplatelet formation

scientific article published on 8 December 2015

Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice

scientific article

Comparative Analysis of Thrombin Calibration Algorithms and Correction for Thrombin-α2macroglobulin Activity

scientific article published on 24 September 2020

Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice

scientific article published on 01 August 2017

Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram.

scientific article published in November 2009

Elevated prothrombin promotes venous, but not arterial, thrombosis in mice.

scientific article published on 30 May 2013

High Content, Label-Free Analysis of Proplatelet Production from Megakaryocytes

scientific article published on 14 July 2020

Human platelets express endothelial protein C receptor, which can be utilized to enhance localization of factor VIIa activity

scientific article published on 27 June 2018

In vitro culture of murine megakaryocytes from fetal liver-derived hematopoietic stem cells

scientific article published on 26 July 2018

Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells

scientific article

Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation

scientific article

Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets

scientific article published on 08 September 2017

Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets

scientific article published on 01 May 2019

Megakaryocyte modification of platelets in thrombocytopenia

scientific article published on 01 September 2018

Modulation of megakaryopoiesis and platelet production during inflammation

scientific article published on 14 May 2019

New Insights Into the Differentiation of Megakaryocytes From Hematopoietic Progenitors

scientific article published on 02 May 2019

Novel gene variants in patients with platelet-based bleeding using combined exome sequencing and RNAseq murine expression data

scientific article published on 06 October 2020

Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.

scientific article published on 31 January 2018

Procoagulant activity induced by vascular injury determines contribution of elevated factor VIII to thrombosis and thrombus stability in mice.

scientific article

Proteasome function is required for platelet production

scientific article (publication date: September 2014)

RBCs pin platelets against the (thrombus) wall.

scientific article

Recombinant factor VIIa analog NN1731 (V158D/E296V/M298Q-FVIIa) enhances fibrin formation, structure and stability in lipidated hemophilic plasma ⬇️

scientific article published on May 10, 2011

Scalable generation of universal platelets from human induced pluripotent stem cells.

scientific article published on 16 October 2014

Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis

scientific article

Smoking out the cause of thrombosis

scientific article published on 01 January 2010

Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation.

scientific article

T granules in human platelets function in TLR9 organization and signaling ⬇️

scientific article published on August 20, 2012

Tamoxifen Directly Inhibits Platelet Angiogenic Potential and Platelet-Mediated Metastasis

scientific article published on 2 February 2017

Teamwork makes the dream work in thrombopoiesis

scientific article published on 01 September 2019

The incredible journey: From megakaryocyte development to platelet formation.

scientific article

Tyrosyl-tRNA synthetase drives megakaryopoiesis independently of thrombopoietin signaling

scientific article published on 11 January 2019

Venous thromboembolism research priorities: A scientific statement from the American Heart Association and the International Society on Thrombosis and Haemostasis

scientific article published on 08 July 2020

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