List of works - Luca G. Guidotti

A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen

scholarly article

Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma ⬇️

scientific article published on June 4, 2013

Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus

scientific article (publication date: November 2007)

Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.

scientific article

Bisphosphonates target B cells to enhance humoral immune responses

scientific article published on 10 October 2013

Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes.

scientific article

Bone marrow as an alternative site for islet transplantation.

scientific article published on 22 September 2009

Characterization of nuclear RNases that cleave hepatitis B virus RNA near the La protein binding site

scientific article published on August 2001

Cytokine-induced viral purging--role in viral pathogenesis.

scientific article

Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes

scientific article

Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming

scientific article published on 02 October 2019

Editorial overview: Viral pathogenesis

scientific article published on 18 March 2015

Effector CD8 T cell trafficking within the liver

scientific article published on 10 November 2012

Effector CD8+ T cell-derived interleukin-10 enhances acute liver immunopathology.

scientific article published on 5 May 2017

Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation

scientific journal article

Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4+ T Cell Help ⬇️

scientific article published on February 29, 2012

Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice

scientific article

Group 1 ILCs regulate T cell–mediated liver immunopathology by controlling local IL-2 availability

scientific article published on 25 February 2022

HBV pathogenesis in animal models: recent advances on the role of platelets

scientific article

High-performance liquid chromatographic determination of d-amino acid oxidase activity ⬇️

scientific article published on May 31, 1991

Host-virus interactions in hepatitis B virus infection.

scientific article published on 14 July 2015

IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment

scientific article published on 14 January 2016

Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

scientific article published on 31 August 2021

Immune pathogenesis of hepatocellular carcinoma.

scientific article

Immune tolerance split between hepatitis B virus precore and core proteins

scientific article

Immunobiology and pathogenesis of viral hepatitis

scientific article published on January 2006

Immunological insights in the treatment of chronic hepatitis B

scientific article published in August 2022

Immunosurveillance of the liver by intravascular effector CD8(+) T cells.

scientific article published on 16 April 2015

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance.

scientific article published in April 2007

In vivo flow mapping in complex vessel networks by single image correlation.

scientific article

Inflammatory monocytes hinder antiviral B cell responses.

scientific article

Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice.

scientific article

Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis

scientific article (publication date: June 2011)

MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.

scientific article published on April 2004

Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis

scientific article

Microcirculation in the murine liver: a computational fluid dynamic model based on 3D reconstruction from in vivo microscopy.

scientific article published on 2 September 2017

Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes

scientific article published on January 2010

Mouse Models of Hepatitis B Virus Pathogenesis

scientific article published on 20 August 2015

Mouse genetics at work: A new model of chronic hepadnavirus infection ⬇️

scientific article published on July 1, 1998

Natural killer T cell activation inhibits hepatitis B virus replication in vivo.

scientific article

Nitric oxide inhibits hepatitis B virus replication in the livers of transgenic mice.

scientific article

Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity

scientific article published on April 2013

Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte.

scientific article

On the role of platelets in the pathogenesis of viral hepatitis

scientific article published on 21 May 2009

Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens

scientific article published on 12 September 2017

Pathogenetic and antiviral immune responses against hepatitis B virus

article

Platelets mediate cytotoxic T lymphocyte-induced liver damage

scientific article

Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.

scientific article

Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes

scientific article

Reduced severity of liver ischemia/reperfusion injury following hepatic resection in humans is associated with enhanced intrahepatic expression of Th2 cytokines

scientific article published on 10 July 2006

Relative sensitivity of hepatitis B virus and other hepatotropic viruses to the antiviral effects of cytokines.

scientific article

Role of CCL2/MCP-1 in islet transplantation

scientific article published on 11 June 2010

Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes

scientific article

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus.

scientific article published on June 2010

TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb ⬇️

scientific article published on 07 May 2013

The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver

article

To kill or to cure: options in host defense against viral infection.

scientific article published on August 1996

Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice

scientific article

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis

scientific article published on October 2008

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

scientific article

List of works by Luca G. Guidotti

A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen

Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma ⬇️

Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus

Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.

Bisphosphonates target B cells to enhance humoral immune responses

Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes.

Bone marrow as an alternative site for islet transplantation.

Characterization of nuclear RNases that cleave hepatitis B virus RNA near the La protein binding site

Cytokine-induced viral purging--role in viral pathogenesis.

Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes

Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming

Editorial overview: Viral pathogenesis

Effector CD8 T cell trafficking within the liver

Effector CD8+ T cell-derived interleukin-10 enhances acute liver immunopathology.

Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation

Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4+ T Cell Help ⬇️

Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice

Group 1 ILCs regulate T cell–mediated liver immunopathology by controlling local IL-2 availability

HBV pathogenesis in animal models: recent advances on the role of platelets

High-performance liquid chromatographic determination of d-amino acid oxidase activity ⬇️

Host-virus interactions in hepatitis B virus infection.

IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment

Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

Immune pathogenesis of hepatocellular carcinoma.

Immune tolerance split between hepatitis B virus precore and core proteins

Immunobiology and pathogenesis of viral hepatitis

Immunological insights in the treatment of chronic hepatitis B

Immunosurveillance of the liver by intravascular effector CD8(+) T cells.

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance.

In vivo flow mapping in complex vessel networks by single image correlation.

Inflammatory monocytes hinder antiviral B cell responses.

Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice.

Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis

MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.

Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis

Microcirculation in the murine liver: a computational fluid dynamic model based on 3D reconstruction from in vivo microscopy.

Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes

Mouse Models of Hepatitis B Virus Pathogenesis

Mouse genetics at work: A new model of chronic hepadnavirus infection ⬇️

Natural killer T cell activation inhibits hepatitis B virus replication in vivo.

Nitric oxide inhibits hepatitis B virus replication in the livers of transgenic mice.

Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity

Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte.

On the role of platelets in the pathogenesis of viral hepatitis

Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens

Pathogenetic and antiviral immune responses against hepatitis B virus

Platelets mediate cytotoxic T lymphocyte-induced liver damage

Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.

Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes

Reduced severity of liver ischemia/reperfusion injury following hepatic resection in humans is associated with enhanced intrahepatic expression of Th2 cytokines

Relative sensitivity of hepatitis B virus and other hepatotropic viruses to the antiviral effects of cytokines.

Role of CCL2/MCP-1 in islet transplantation

Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus.

TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb ⬇️

The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver

To kill or to cure: options in host defense against viral infection.

Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection