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List of works by Robert K. Andrews

14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

scientific article published on 27 September 2016

A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway.

scientific article published in June 2007

A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene

scientific article

A-Disintegrin-And-Metalloproteinase (ADAM) 10 Activity on Resting and Activated Platelets

scientific article published on 3 February 2016

ARQ 092, an orally-available, selective AKT inhibitor, attenuates neutrophil-platelet interactions in sickle cell disease

scientific article published on 06 October 2016

Activated platelets rescue apoptotic cells via paracrine activation of EGFR and DNA-dependent protein kinase.

scientific article

Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein Ibα.

scientific article

An acquired defect associated with abnormal signaling of the platelet collagen receptor glycoprotein VI.

scientific article

An atypical IgM class platelet cold agglutinin induces GPVI-dependent aggregation of human platelets.

scientific article

An event of shear importance

scientific article published on 01 January 2011

Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V

scientific article published on 01 August 2006

Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding.

scientific article published in March 2009

Autoregulation of von Willebrand factor function by a disulfide bond switch.

scientific article published on 28 February 2018

Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

scientific article

Bone Marrow Defects and Platelet Function: A Focus on MDS and CLL.

scientific article

CLEC-2 expression is maintained on activated platelets and on platelet microparticles.

scientific article

Calmodulin interacts with the platelet ADP receptor P2Y1

scientific article published on September 2006

Circulating levels of soluble EMMPRIN (CD147) correlate with levels of soluble glycoprotein VI in human plasma.

scientific article

Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets.

scientific article published on 06 January 2017

Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa

scientific article published on 20 January 2011

Conotoxin engineering: dual pharmacophoric noradrenaline transport inhibitor/integrin binding peptide with improved stability

scientific article published on 11 May 2012

Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases.

scientific article published on 18 April 2007

Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function.

scientific article published on 30 August 2017

Current state and novel approaches of antiplatelet therapy

scientific article

Decreased levels of platelet-derived soluble glycoprotein VI detected prior to the first diagnosis of coronary artery disease in HIV-positive individuals.

scientific article published on 16 November 2016

DiagnoSTic assays for heparin-induced thrombocytopenia

scientific article

Dimeric FcγR ectodomains detect pathogenic anti-platelet factor 4-heparin antibodies in heparin-induced thromobocytopenia

scientific article published on 20 November 2018

Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: de-ITAM-izing FcgammaRIIa

scientific article

Editorial: ADAMs control inflammation from afar

scientific article published on March 2015

Effects of abacavir administration on structural and functional markers of platelet activation.

scientific article

Exacerbation of glycoprotein VI-dependent platelet responses in a rhesus monkey model of Type 1 diabetes

scientific article published on 06 June 2013

Extracorporeal membrane oxygenation-hemostatic complications.

scientific article

Focusing on plasma glycoprotein VI.

scientific article

FoxO function PAR excellence...

scientific article published on 25 May 2012

Functional association of phosphoinositide-3-kinase with platelet glycoprotein Ibalpha, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex.

scientific article published on 30 October 2009

GPIbalpha-selective activation of platelets induces platelet signaling events comparable to GPVI activation events

scientific article published in January 2010

Glycoprotein Ib-IX-V.

scientific article

Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism

scientific article published on 2 September 2009

High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction

scientific article

ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways.

scientific article

Inhibition of protease-activated receptor 4 impairs platelet procoagulant activity during thrombus formation in human blood

scientific article published on 15 February 2016

Inside platelets..

scientific article published on 01 January 2012

Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor.

scientific article published on 14 June 2006

Liver-mediated shedding of platelet GPVI.

scientific article

Longitudinal changes in hemostatic parameters and reduced pulsatility contribute to non-surgical bleeding in patients with centrifugal continuous-flow left ventricular assist devices

scientific article published on 7 January 2016

Low adhesion receptor levels on circulating platelets in patients with lymphoproliferative diseases before receiving Navitoclax (ABT-263).

scientific article published in February 2013

Lymphomania

scientific article published on 01 May 2014

M1761K mutation in the von Willebrand factor A3 domain associated with impaired collagen binding and without platelet dysfunction

scientific article published on 28 June 2016

Measuring soluble platelet glycoprotein VI in human plasma by ELISA.

scientific article

Mechanical circulatory support is associated with loss of platelet receptors glycoprotein Ibα and glycoprotein VI.

scientific article published on 7 September 2016

Mechanisms of Platelet Dysfunction in Patients with Implantable Devices

scientific article published on 12 September 2017

Mechanisms of receptor shedding in platelets

article

Methods to Determine the Lagrangian Shear Experienced by Platelets during Thrombus Growth

scientific article published on 14 December 2015

Monitoring the pulse of thrombus formation

scientific article published on 24 July 2018

NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis

article

NOX2 is critical for heterotypic neutrophil-platelet interactions during vascular inflammation

scientific article

Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI

scientific article

Neutrophil extracellular traps (NETs) and infection-related vascular dysfunction

scientific article published on 26 September 2012

Neutrophil extracellular traps (NETs) and the role of platelets in infection

article

New insights into the haemostatic function of platelets.

scientific article

Novel Stenotic Microchannels to Study Thrombus Formation in Shear Gradients: Influence of Shear Forces and Human Platelet-Related Factors

scientific article published on 18 June 2019

Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels

scientific article published on 19 March 2012

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators

scientific article

Plasma sGPVI: Changing levels in human disease.

scientific article published on 22 December 2013

Platelet Ubiquitylation-It's Everywhere

scientific article published on 31 December 2018

Platelet hem-immunoreceptor tyrosine-based activation motif receptors: at least one required.

scientific article published in May 2013

Platelet interactions in thrombosis

scientific article published on January 2004

Platelet physiology and thrombosis.

scientific article published in January 2004

Platelet physiology: in cold blood.

scientific article

Platelet receptor expression and shedding: glycoprotein Ib-IX-V and glycoprotein VI.

scientific article

Platelet receptor shedding

scientific article published on January 2012

Platelets: envoys at the infection frontline

scientific article

Primary haemostasis: newer insights.

scientific article published on May 2014

Primary platelet adhesion receptors

scientific article

Programmed autologous cleavage of platelet receptors.

scientific article published on July 2007

Protein tyrosine phosphatase PTPN22 negatively modulates platelet function and thrombus formation

scientific article published in 2022

Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase

scientific article

Role of calmodulin in platelet receptor function

scientific article

Short and sweet science

scientific article published on 23 June 2019

Snake venom probes of platelet adhesion receptors and their ligands

scientific article

Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI

article

Soluble Glycoprotein VI Is Raised in the Plasma of Patients With Acute Ischemic Stroke

article

Soluble glycoprotein VI, a specific marker of platelet activation is increased in the plasma of subjects with seropositive rheumatoid arthritis

scientific article published on 15 November 2017

Structure and function of platelet receptors initiating blood clotting

scientific article

TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets.

scientific article

Targeting GPVI as a novel antithrombotic strategy

scientific article

Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides: comment.

scientific article published on 20 October 2017

The 14-3-3zeta-GPIb-IX-V complex as an antiplatelet target.

scientific article published on June 2007

The NET effect of clot formation

scientific article published on 01 January 2012

The cutting edge of platelets

scientific article published in June 2017

The identification of a calmodulin-binding domain within the cytoplasmic tail of angiotensin-converting enzyme-2.

scientific article

The platelet Fc receptor, FcγRIIa

scientific article

Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα.

scientific article published on 28 October 2015

Thrombotic thrombocytopenic purpura: reducing the risk?

scientific article

Transmembrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibalpha.

scientific article

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