List of works - Paul F. O'Reilly

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A new method for identifying causal genes of schizophrenia and anti-tuberculosis drug-induced hepatotoxicity

scientific article published on September 2016

Admixture provides new insights into recombination ⬇️

scientific article published on August 29, 2011

An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis

scientific article

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

scientific article published on 08 October 2018

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression

scientific article

Association of Polygenic Risk for Attention-Deficit/Hyperactivity Disorder With Co-occurring Traits and Disorders

scientific article published on 14 December 2017

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Assortative Mating-A Missing Piece in the Jigsaw of Psychiatric Genetics

scientific article published on 24 February 2016

Body composition in anorexia nervosa: Meta-analysis and meta-regression of cross-sectional and longitudinal studies

scientific article published on 12 September 2019

Cannabis use, depression and self-harm: phenotypic and genetic relationships

scientific article published on 12 December 2019

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

scientific article published on 05 August 2019

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Common genetic variants regulating ADD3 gene expression alter biliary atresia risk.

scientific article published on 19 July 2013

Common variants at 12q15 and 12q24 are associated with infant head circumference

scientific article published on 15 April 2012

Common variation near ROBO2 is associated with expressive vocabulary in infancy.

scientific article

Confounding between recombination and selection, and the Ped/Pop method for detecting selection

scientific article published on 10 July 2008

Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

scientific article published on 18 May 2020

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci

scientific article

Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference

scholarly article published in Nature Genetics

Evolutionary and functional impact of common polymorphic inversions in the human genome

scientific article published on 17 September 2019

Fine-scale estimation of location of birth from genome-wide single-nucleotide polymorphism data

scientific article

Fregene: simulation of realistic sequence-level data in populations and ascertained samples

scientific article

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

scientific article published on 04 September 2019

Genetic Effects, Categorical Disorders, and Quantitative Traits

scientific article published in September 2015

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

scientific article published on 18 December 2019

Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

scientific article published on 30 January 2017

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

scientific article published on 17 January 2018

Genome-wide association study reveals multiple loci associated with primary tooth development during infancy

scientific article

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

article

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

scientific article published on 23 January 2020

Genomics of body fat percentage may contribute to sex bias in anorexia nervosa

article

Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trial

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

Investigating the effects of genetic risk of schizophrenia on behavioural traits

scientific article published in 2021

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

scientific article

Knee pain and disability in the Nottingham community: association with poor health status and psychological distress

scientific article published in August 1998

Long-term leisure-time physical activity and serum metabolome

scientific article published on 20 December 2012

Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant.

scientific article

Multi-polygenic score approach to trait prediction ⬇️

scientific article

MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS.

scientific article

Multiple measures of adiposity are associated with mean leukocyte telomere length in the northern Finland birth cohort 1966.

scientific article

Multivariate simulation framework reveals performance of multi-trait GWAS methods

scientific article published on 13 March 2017

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

PRSice: Polygenic Risk Score software

scientific article published on 29 December 2014

Phenome-wide analysis of genome-wide polygenic scores.

scientific article published on 25 August 2015

Predicting educational achievement from DNA

scientific article published on 26 September 2017

Predicting educational achievement from DNA.

scientific article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Rsu1 regulates ethanol consumption in Drosophila and humans

scientific article published on 13 July 2015

Screening for hand osteoarthritis (OA) using a postal survey

scientific article published in September 1999

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

The South Asian genome.

scientific article

The effect of genomic inversions on estimation of population genetic parameters from SNP data

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

Translating genome-wide association findings into new therapeutics for psychiatry

scientific article

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

scientific article

Widespread covariation of early environmental exposures and trait-associated polygenic variation.

scientific article published on 16 October 2017

invertFREGENE: software for simulating inversions in population genetic data.

scientific article

List of works by Paul F. O'Reilly

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

A new method for identifying causal genes of schizophrenia and anti-tuberculosis drug-induced hepatotoxicity

Admixture provides new insights into recombination ⬇️

An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression

Association of Polygenic Risk for Attention-Deficit/Hyperactivity Disorder With Co-occurring Traits and Disorders

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Assortative Mating-A Missing Piece in the Jigsaw of Psychiatric Genetics

Body composition in anorexia nervosa: Meta-analysis and meta-regression of cross-sectional and longitudinal studies

Cannabis use, depression and self-harm: phenotypic and genetic relationships

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

Common genetic variants regulating ADD3 gene expression alter biliary atresia risk.

Common variants at 12q15 and 12q24 are associated with infant head circumference

Common variation near ROBO2 is associated with expressive vocabulary in infancy.

Confounding between recombination and selection, and the Ped/Pop method for detecting selection

Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci

Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference

Evolutionary and functional impact of common polymorphic inversions in the human genome

Fine-scale estimation of location of birth from genome-wide single-nucleotide polymorphism data

Fregene: simulation of realistic sequence-level data in populations and ascertained samples

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

Genetic Effects, Categorical Disorders, and Quantitative Traits

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

Genome-wide association study identifies eight loci associated with blood pressure

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

Genome-wide association study reveals multiple loci associated with primary tooth development during infancy

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Genomics of body fat percentage may contribute to sex bias in anorexia nervosa

Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trial

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Identification of seven loci affecting mean telomere length and their association with disease

Investigating the effects of genetic risk of schizophrenia on behavioural traits

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Knee pain and disability in the Nottingham community: association with poor health status and psychological distress

Long-term leisure-time physical activity and serum metabolome

Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant.

Multi-polygenic score approach to trait prediction ⬇️

MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS.

Multiple measures of adiposity are associated with mean leukocyte telomere length in the northern Finland birth cohort 1966.

Multivariate simulation framework reveals performance of multi-trait GWAS methods

New gene functions in megakaryopoiesis and platelet formation

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

PRSice: Polygenic Risk Score software

Phenome-wide analysis of genome-wide polygenic scores.

Predicting educational achievement from DNA

Predicting educational achievement from DNA.

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Rsu1 regulates ethanol consumption in Drosophila and humans

Screening for hand osteoarthritis (OA) using a postal survey

Seventy-five genetic loci influencing the human red blood cell

The South Asian genome.

The effect of genomic inversions on estimation of population genetic parameters from SNP data

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Translating genome-wide association findings into new therapeutics for psychiatry

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

Widespread covariation of early environmental exposures and trait-associated polygenic variation.

invertFREGENE: software for simulating inversions in population genetic data.