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List of works by Philip R. Holland

A translational in vivo model of trigeminal autonomic cephalalgias: therapeutic characterization

scientific article

Acid-sensing ion channel 1: a novel therapeutic target for migraine with aura.

scientific article published in October 2012

Acid-sensing ion channel 3 blockade inhibits durovascular and nitric oxide-mediated trigeminal pain

scientific article published on 23 January 2020

An Update: Pathophysiology of Migraine

scientific article published on 01 November 2019

Animal models of migraine and experimental techniques used to examine trigeminal sensory processing

scientific article published on 29 August 2019

Animal models of migraine: looking at the component parts of a complex disorder.

scientific article published on September 2006

Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice

scientific article published on 30 June 2017

Cluster headache, hypothalamus, and orexin.

scientific article published on April 2009

Controlled hypertension induces cerebrovascular and gene alterations in Cyp1a1-Ren2 transgenic rats.

scientific article published on 8 October 2013

Cortical spreading depression-associated cerebral blood flow changes induced by mechanical stimulation are modulated by AMPA and GABA receptors.

scientific article published in May 2010

Current and novel insights into the neurophysiology of migraine and its implications for therapeutics.

scientific article published on 2 December 2016

Diencephalic and brainstem mechanisms in migraine

scientific article

Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators.

scientific article

Divergent influences of the locus coeruleus on migraine pathophysiology

scientific article published on 01 February 2019

Foreword: The CGRP Pathway and Migraine Prevention: Reducing the Burden of Disease

scientific article published on 01 May 2018

Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease

scientific article

Headache and sleep: shared pathophysiological mechanisms.

scientific article

Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats

scientific article published on 19 November 2014

Involvement of corticotrophin-releasing factor and orexin-A in chronic migraine and medication overuse headache: findings from cerebrospinal fluid.

scientific article published on 13 May 2008

MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice

scientific article published on 30 December 2010

Mechanically-induced cortical spreading depression associated regional cerebral blood flow changes are blocked by Na+ ion channel blockade

scientific article

Migraine Therapy: Current Approaches and New Horizons.

scientific article published on 17 April 2018

Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

scientific article

Modulation of nociceptive dural input to the trigeminal nucleus caudalis via activation of the orexin 1 receptor in the rat.

scientific article published in November 2006

Modulation of nociceptive dural input to the trigeminocervical complex through GluK1 kainate receptors

scientific article published on March 2015

Modulation of trigeminovascular processing: novel insights into primary headache disorders.

scientific article published on December 2009

Neurobiology of migraine

scientific article published on 19 March 2009

Neuroendocrine signaling modulates specific neural networks relevant to migraine

scientific article

Neurons of the dopaminergic/calcitonin gene-related peptide A11 cell group modulate neuronal firing in the trigeminocervical complex: an electrophysiological and immunohistochemical study

scientific article published in October 2009

Nitroglycerine triggers triptan-responsive cranial allodynia and trigeminal neuronal hypersensitivity

scientific article published on 01 January 2019

Occipital afferent activation of second order neurons in the trigeminocervical complex in rat.

scientific article published on 24 May 2006

Orexin 1 receptor activation attenuates neurogenic dural vasodilation in an animal model of trigeminovascular nociception.

scientific article

PACAP in hypothalamic regulation of sleep and circadian rhythm: importance for headache.

scientific article

Pathophysiology of Migraine: A Disorder of Sensory Processing

scientific article published on April 2017

Pearls and pitfalls in experimental in vivo models of migraine: Dural trigeminovascular nociception ⬇️

scientific article published on June 1, 2013

Rapid uptake of sumatriptan into the brain: An ongoing question of blood-brain barrier permeability

scientific article published on 30 January 2020

Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion

scientific article (publication date: 2014)

Subjective Sleep Quality and Sleep Architecture in Patients With Migraine: A Meta-analysis

scientific article published on 22 September 2021

The hypothalamic orexinergic system: pain and primary headaches.

scientific article published on June 2007

The role of the brainstem in migraine: Potential brainstem effects of CGRP and CGRP receptor activation in animal models

scientific article published in January 2018

Transcranial magnetic stimulation and potential cortical and trigeminothalamic mechanisms in migraine

scientific article

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