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List of works by Isabel Marzo

A Cytofluorometric Assay of Nuclear Apoptosis Induced in a Cell-Free System: Application to Ceramide-Induced Apoptosis

A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

scientific article published in August 2001

Alternative route for the biosynthesis of polyunsaturated fatty acids in K562 cells.

scientific article published on May 1993

Apoptosis by IL-2 deprivation in human CD8+ T cell blasts predominates over death receptor ligation, requires Bim expression and is associated with Mcl-1 loss

article

Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

scientific article published on 01 June 1999

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

scientific article

Bcl-2 family members as molecular targets in cancer therapy.

scientific article published on 28 June 2008

Bcl-2 family of proteins as drug targets for cancer chemotherapy: the long way of BH3 mimetics from bench to bedside.

scientific article published on 14 June 2015

Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells.

scientific article

Bioactive and luminescent indole and isatin based gold(i) derivatives

scientific article published on 01 February 2019

Biological evaluation of water soluble arene Ru(II) enantiomers with amino-oxime ligands

scientific article published on 06 March 2018

Biosynthesis of docosahexaenoic acid in human cells: evidence that two different delta 6-desaturase activities may exist

scientific article published on 01 June 1996

Biosynthesis of unsaturated fatty acids in the main cell lineages of human leukemia and lymphoma.

scientific article published on July 1995

Bortezomib resistance in a myeloma cell line is associated to PSMβ5 overexpression and polyploidy

scientific article published on 5 October 2011

CPP32 inhibition prevents Fas-induced ceramide generation and apoptosis in human cells.

scientific article published on July 1996

Caspases disrupt mitochondrial membrane barrier function.

scientific article published in May 1998

Cell fate after mitotic arrest in different tumor cells is determined by the balance between slippage and apoptotic threshold ⬇️

scientific article published on December 9, 2011

Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria ⬇️

scientific article published on November 1, 2001

Cooperation between Apo2L/TRAIL and bortezomib in multiple myeloma apoptosis.

scientific article

Cyclometalated Iminophosphorane Gold(III) and Platinum(II) Complexes. A Highly Permeable Cationic Platinum(II) Compound with Promising Anticancer Properties

scientific article

Cytotoxic hydrophilic iminophosphorane coordination compounds of d8 metals. Studies of their interactions with DNA and HSA ⬇️

scientific article published on July 6, 2012

Cytotoxicity and biodistribution studies of luminescent Au(i) and Ag(i) N-heterocyclic carbenes. Searching for new biological targets

scientific article published on 25 August 2016

Different contribution of BH3-only proteins and caspases to doxorubicin-induced apoptosis in p53-deficient leukemia cells.

scientific article

Direct interaction of Bax and Bak proteins with Bcl-2 homology domain 3 (BH3)-only proteins in living cells revealed by fluorescence complementation.

scientific article published on 2 January 2013

Down-regulation of normal human T cell blast activation: roles of APO2L/TRAIL, FasL, and c- FLIP, Bim, or Bcl-x isoform expression.

scientific article published on 14 January 2005

Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells.

scientific article published in October 2004

Farnesyltransferase inhibitor BMS-214662 induces apoptosis in myeloma cells through PUMA up-regulation, Bax and Bak activation, and Mcl-1 elimination.

scientific article published on 28 February 2005

Gold(I) thiolates containing amino acid moieties. Cytotoxicity and structure-activity relationship studies.

scientific article published on December 2014

Granulysin induces apoptotic cell death and cleavage of the autophagy regulator Atg5 in human hematological tumors.

scientific article

High-order TRAIL oligomer formation in TRAIL-coated lipid nanoparticles enhances DR5 cross-linking and increases antitumour effect against colon cancer

scientific article published on 8 October 2016

Highly active group 11 metal complexes with α-hydrazidophosphonate ligands

scientific article

Highly cytotoxic bioconjugated gold(I) complexes with cysteine-containing dipeptides.

scientific article

Human CD8+ T cell blasts are more sensitive than CD4+ T cell blasts to regulation by APO2L/TRAIL

scientific article published on 01 June 2005

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

scientific article published on 9 January 2015

Iminophosphorane-organogold(III) complexes induce cell death through mitochondrial ROS production ⬇️

scientific article published on June 24, 2011

Immunogenic Cell Death and Immunotherapy of Multiple Myeloma

scientific article published on 16 April 2019

Immunotherapy with liposome-bound TRAIL overcomes partial protection to soluble TRAIL-induced apoptosis offered by down-regulation of Bim in leukemic cells

scientific article published on 13 May 2015

In vitro and in vivo evaluation of water-soluble iminophosphorane ruthenium(II) compounds. A potential chemotherapeutic agent for triple negative breast cancer

scientific article

Individual variation of scavenger receptor expression in human macrophages with oxidized low-density lipoprotein is associated with a differential inflammatory response

scientific article published on 01 September 2007

Inhibition of autophagy with chloroquine potentiates carfilzomib-induced apoptosis in myeloma cells in vitro and in vivo

scientific article published on 24 August 2016

Liposomes Decorated with Apo2L/TRAIL Overcome Chemoresistance of Human Hematologic Tumor Cells ⬇️

scientific article published on February 6, 2013

Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore

article

Luminescent Bimetallic IrIII /AuI Peptide Bioconjugates as Potential Theranostic Agents

scientific article published on 31 August 2020

Luminescent Re(i) and Re(i)/Au(i) complexes as cooperative partners in cell imaging and cancer therapy

Mechanism of apoptosis induced by IFN-alpha in human myeloma cells: role of Jak1 and Bim and potentiation by rapamycin.

scientific article

Mitochondrial release of caspase-2 and -9 during the apoptotic process

scientific article

Molecular characterization of mitochondrial apoptosis-inducing factor

scientific article

Multifaceted anticancer activity of BH3 mimetics: Current evidence and future prospects.

scientific article published on 10 March 2017

Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.

scientific article published in June 1997

Organometallic Palladium Complexes with a Water-Soluble Iminophosphorane Ligand as Potential Anticancer Agents.

scientific article

Self-staining of polyunsaturated fatty acids in argentation thin-layer chromatography

scientific article published on 01 July 1994

Synthesis of luminescent squaramide monoesters: cytotoxicity and cell imaging studies in HeLa cells

scholarly article in RSC Advances, vol. 6 no. 17, 2016

Targeting the Apo2L/TRAIL system for the therapy of autoimmune diseases and cancer.

scientific article published on 02 January 2012

The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins ⬇️

scientific article published on April 20, 1998

The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes ⬇️

scientific article published on January 1, 1998

Trackable Metallodrugs Combining Luminescent Re(I) and Bioactive Au(I) Fragments

scientific article

Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis.

scientific article

Ylide Ligands as Building Blocks for Bioactive Group 11 Metal Complexes

scientific article published on 13 July 2018

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