List of works by Peter Andersen

13 ESAT-6 and the Mycobacterial ESX Secretion Systems

A Liposome-Based Adjuvant Containing Two Delivery Systems with the Ability to Induce Mucosal Immunoglobulin A Following a Parenteral Immunization

scientific article published on 18 January 2019

A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10)

scientific journal article

A New Experimental Infection Model in Ferrets Based on Aerosolised Mycobacterium bovis

scientific article published on 12 April 2011

A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo

article

A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog

A comparative study of cationic liposome and niosome-based adjuvant systems for protein subunit vaccines: characterisation, environmental scanning electron microscopy and immunisation studies in mice

scientific article published on 01 June 2006

A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells

scientific article

A multi-subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN-γ⁺ CMI responses protects against a genital infection in minipigs

scientific article published on 13 August 2015

A multistage tuberculosis vaccine that confers efficient protection before and after exposure.

scientific article

A novel TB vaccine; strategies to combat a complex pathogen

scientific article

A novel TB vaccine; towards a strategy based on our understanding of BCG failure.

scientific article

A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis-specific T-cell responses in human

scientific article published on 30 October 2014

A novel liposome-based adjuvant CAF01 for induction of CD8(+) cytotoxic T-lymphocytes (CTL) to HIV-1 minimal CTL peptides in HLA-A*0201 transgenic mice

scientific article

A simple mycobacterial monomycolated glycerol lipid has potent immunostimulatory activity

scientific article

A stable nanoparticulate DDA/MMG formulation acts synergistically with CpG ODN 1826 to enhance the CD4⁺ T-cell response

scientific article published on December 2014

A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion antigen CTH522.

scientific article

A structurally informed autotransporter platform for efficient heterologous protein secretion and display

scientific article published on 18 June 2012

Adaptive Immunity against Streptococcus pyogenes in Adults Involves Increased IFN-γ and IgG3 Responses Compared with Children

scientific article published on 10 July 2015

Adjuvant modulation of the cytokine balance in Mycobacterium tuberculosis subunit vaccines; immunity, pathology and protection

scholarly article by Else Marie Agger et al published June 2008 in Immunology

Adjuvant properties of a simplified C32 monomycolyl glycerol analogue

scientific article published on 11 February 2009

Adjuvanted HLA-supertype restricted subdominant peptides induce new T-cell immunity during untreated HIV-1-infection.

scientific article published on 21 December 2012

Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation

scientific article

Adjuvants induce distinct immunological phenotypes in a bovine tuberculosis vaccine model

scientific article published on 29 July 2009

Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant

scientific article

Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers

scientific article published on 11 March 2010

Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization.

scientific article published on 28 October 2016

Alteration of epitope recognition pattern in Ag85B and ESAT-6 has a profound influence on vaccine-induced protection against Mycobacterium tuberculosis

scientific article published on December 2006

Aluminium hydroxide potentiates a protective Th1 biased immune response against polio virus that allows for dose sparing in mice and rats

scientific article published on 17 February 2015

An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology

scientific article

An autotransporter display platform for the development of multivalent recombinant bacterial vector vaccines

scientific article

Analysis of protein species differentiation among mycobacterial low-Mr-secreted proteins by narrow pH range Immobiline gel 2-DE-MALDI-MS.

scientific article

Anti-tumoral effect of active immunotherapy in C57BL/6 mice using a recombinant human VEGF protein as antigen and three chemically unrelated adjuvants

scientific article

Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis

scientific article

Antibody responses in reindeer (Rangifer tarandus) infected with Mycobacterium bovis

scientific article

Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis

scientific article published on June 2017

Antigen Discovery and Tuberculosis Vaccine Development in the Post-genomic Era

article

Antigen recognition by serum antibodies in white-tailed deer (Odocoileus virginianus) experimentally infected with Mycobacterium bovis.

scientific article published on September 2004

Antigenic equivalence of human T-cell responses to Mycobacterium tuberculosis-specific RD1-encoded protein antigens ESAT-6 and culture filtrate protein 10 and to mixtures of synthetic peptides

scientific article

Antiviral Innate Immune Activation in HIV-Infected Adults Negatively Affects H1/IC31-Induced Vaccine-Specific Memory CD4+ T Cells

scientific article published on 29 April 2015

Assessing the serodiagnostic potential of 35 Mycobacterium tuberculosis proteins and identification of four novel serological antigens

scientific article

Assessment of defined antigens for the diagnosis of bovine tuberculosis in skin test-reactor cattle

scientific article published on 01 June 2000

Association of tuberculin-boosted antibody responses with pathology and cell-mediated immunity in cattle vaccinated with Mycobacterium bovis BCG and infected with M. bovis

scientific article

Authors' Reply

scientific article published in 2002

Bettering BCG: a tough task for a TB vaccine?

scientific article published in April 2013

Broadening CD4+ and CD8+ T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes

scientific article published on 26 April 2017

Broadening of the T-cell repertoire to HIV-1 Gag p24 by vaccination of HLA-A2/DR transgenic mice with overlapping peptides in the CAF05 adjuvant

scientific article

C-Tb skin test to diagnose Mycobacterium tuberculosis infection in children and HIV-infected adults: A phase 3 trial

scientific article published in PLoS ONE

CAF01 liposomes as a mucosal vaccine adjuvant: In vitro and in vivo investigations

scientific article published on 29 October 2009

CAF01 potentiates immune responses and efficacy of an inactivated influenza vaccine in ferrets

scientific article (publication date: 2011)

CAF05: cationic liposomes that incorporate synthetic cord factor and poly(I:C) induce CTL immunity and reduce tumor burden in mice

CD4 and CD8 T cell responses to the M. tuberculosis Ag85B-TB10.4 promoted by adjuvanted subunit, adenovector or heterologous prime boost vaccination

scientific article

CD4 and CD8 T-cell responses to mycobacterial antigens in African children

scientific article

CD4(+) T-cell subsets that mediate immunological memory to Mycobacterium tuberculosis infection in mice

scientific article

CFP10 discriminates between nonacetylated and acetylated ESAT-6 of Mycobacterium tuberculosis by differential interaction

scientific article

CFP10 discriminates between nonacetylated and acetylated ESAT-6 ofMycobacterium tuberculosis by differential interaction

scholarly article

Cationic liposomal vaccine adjuvants in animal challenge models: overview and current clinical status

scientific article published on May 2012

Cationic liposomes as vaccine adjuvants

scientific article published on October 2007

Cationic liposomes containing mycobacterial lipids: a new powerful Th1 adjuvant system

scientific article

Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements

scientific article

Cell-mediated and humoral immune responses after immunization of calves with a recombinant multiantigenic Mycobacterium avium subsp. paratuberculosis subunit vaccine at different ages

scientific article published on 6 February 2013

Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy

scientific article published on April 2016

Characterisation of a live Salmonella vaccine stably expressing the Mycobacterium tuberculosis Ag85B-ESAT6 fusion protein

scientific article published on 13 September 2009

Characterization of a Mycobacterium tuberculosis peptide that is recognized by human CD4+ and CD8+ T cells in the context of multiple HLA alleles

scientific article

Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6'-dibehenate)-a novel adjuvant inducing both strong CMI and antibody responses

scientific article published on 14 November 2005

Characterization of protective immune responses promoted by human antigen targets in a urogenital Chlamydia trachomatis mouse model

scientific article published on 21 December 2013

Characterization of the Antigen-Specific CD4(+) T Cell Response Induced by Prime-Boost Strategies with CAF01 and CpG Adjuvants Administered by the Intranasal and Subcutaneous Routes

scientific article

Chlamydia muridarum T cell antigens and adjuvants that induce protective immunity in mice

scientific article published on 30 January 2012

Co-Infection of cattle with Fasciola hepatica and Mycobacterium bovis- immunological consequences.

scientific article published in August 2009

Combination of the cationic surfactant dimethyl dioctadecyl ammonium bromide and synthetic mycobacterial cord factor as an efficient adjuvant for tuberculosis subunit vaccines

scientific article published on March 2004

Comparative Analysis of Different Vaccine Constructs Expressing Defined Antigens fromMycobacterium tuberculosis

article

Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants

scientific article published on 13 December 2016

Comparing adjuvanted H28 and modified vaccinia virus ankara expressingH28 in a mouse and a non-human primate tuberculosis model

scientific article

Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak

scientific article

Comparison of the Depot Effect and Immunogenicity of Liposomes Based on Dimethyldioctadecylammonium (DDA), 3β-[N-(N′,N′-Dimethylaminoethane)carbomyl] Cholesterol (DC-Chol), and 1,2-Dioleoyl-3-trimethylammonium Propane (DOTAP): Prolonged Liposome

Comparison of tuberculin skin test and new specific blood test in tuberculosis contacts

scientific article

Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration

article

Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques

scientific article published on 12 October 2018

Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques

scholarly article published 29 August 2018

Control of chronic mycobacterium tuberculosis infection by CD4 KLRG1- IL-2-secreting central memory cells

scientific article published on 15 May 2013

Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells

scholarly article by Laurens A.H. van Pinxteren et al published December 2000 in European Journal of Immunology

Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells

scientific article published on 01 December 2000

Correction: Difference in TB10.4 T-cell epitope recognition following immunization with recombinant TB10.4, BCG or infection with Mycobacterium tuberculosis

article

Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate

scientific article

Cyclooxygenase inhibitors impair CD4 T cell immunity and exacerbate Mycobacterium tuberculosis infection in aerosol-challenged mice

scientific article published on 05 August 2019

Cytokine profiles in tuberculosis patients and healthy subjects in response to complex and single antigens of Mycobacterium tuberculosis

article

Deciphering the proteome of the in vivo diagnostic reagent "purified protein derivative" from Mycobacterium tuberculosis

scientific article published on April 2012

Design of Gadoteridol-Loaded Cationic Liposomal Adjuvant CAF01 for MRI of Lung Deposition of Intrapulmonary Administered Particles

scientific article published on 03 October 2019

Designing CAF-adjuvanted dry powder vaccines: spray drying preserves the adjuvant activity of CAF01.

scientific article published on 8 February 2013

Detecting a low prevalence of latent tuberculosis among health care workers in Denmark detected by M. tuberculosis specific IFN-gamma whole-blood test

scientific article published in January 2007

Detection of Active Tuberculosis Infection by T Cell Responses to Early‐Secreted Antigenic Target 6‐kDa Protein and Culture Filtrate Protein 10

article

Detection of bovine tuberculosis in herds with different disease prevalence and influence of paratuberculosis infection on PPDB and ESAT-6/CFP10 specificity

scientific article published on 14 July 2010

Detection of proliferative responses to ESAT-6 and CFP-10 by FASCIA assay for diagnosis of Mycobacterium tuberculosis infection

scientific article published on 30 May 2011

Determining Adjuvant Activity on T-Cell Function In Vivo: Th Cells

article published in 2009

Developing solid particulate vaccine adjuvants: surface bound antigen favours a humoural response, whereas entrapped antigen shows a tendency for cell mediated immunity

scientific article published in June 2013

Development and preclinical safety evaluation of a new therapeutic HIV-1 vaccine based on 18 T-cell minimal epitope peptides applying a novel cationic adjuvant CAF01.

scientific article published on 19 July 2011

Development of a proof of concept immunochromatographic lateral flow assay for point of care diagnosis of Mycobacterium tuberculosis

scientific article

Diagnosis of latent Mycobacterium tuberculosis infection: is the demise of the Mantoux test imminent?

scientific article

Diagnosis of tuberculosis based on the two specific antigens ESAT-6 and CFP10.

scientific article

Diagnostic Performance of Tuberculosis-Specific IgG Antibody Profiles in Patients with Presumptive Tuberculosis from Two Continents.

scientific article published on April 2017

Diagnostic accuracy of ESAT-6 free IGRA compared to QuantiFERON-TB Gold In-tube

scientific article published on 01 October 2019

Difference in TB10.4 T-cell epitope recognition following immunization with recombinant TB10.4, BCG or infection with Mycobacterium tuberculosis

article

Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

scientific article published on 21 January 2016

Differential influence of nutrient-starved Mycobacterium tuberculosis on adaptive immunity results in progressive tuberculosis disease and pathology

scientific article

Direct contact with endoderm-like cells efficiently induces cardiac progenitors from mouse and human pluripotent stem cells

scientific article (publication date: 2012)

Distinct differences in the expansion and phenotype of TB10.4 specific CD8 and CD4 T cells after infection with Mycobacterium tuberculosis

scientific article

Dose Optimization of H56:IC31 Vaccine for TB Endemic Populations: A Double-Blind, Placebo-Controlled, Dose-Selection Trial

scientific article published on 01 January 2019

Double-blind randomized Phase I study comparing rdESAT-6 to tuberculin as skin test reagent in the diagnosis of tuberculosis infection

scientific article published on 26 December 2007

Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization

article

Duchenne muscular dystrophy hiPSC-derived myoblast drug screen identifies compounds that ameliorate disease in mdx mice

scientific article published on 28 April 2020

ESAT-6 (EsxA) and TB10.4 (EsxH) based vaccines for pre- and post-exposure tuberculosis vaccination

scientific article

ESAT-6 and CFP-10 in clinical versus environmental isolates of Mycobacterium kansasii

scientific article published on 15 March 2005

ESAT-6 proteins: protective antigens and virulence factors?

scientific article

ESAT-6 subunit vaccination against Mycobacterium tuberculosis

scientific article

ESAT-6/CFP10 skin test predicts disease in M. tuberculosis-infected guinea pigs

scientific article

Early antibody responses to experimental Mycobacterium bovis infection of cattle

scientific article

Effect of different adjuvants on the immune responses of cattle vaccinated with Mycobacterium tuberculosis culture filtrate proteins.

scientific article

Effect of sample handling on analysis of cytokine responses to Mycobacterium tuberculosis in clinical samples using ELISA, ELISPOT and quantitative PCR.

scientific article published in March 2005

Efficient protection against Mycobacterium tuberculosis by vaccination with a single subdominant epitope from the ESAT-6 antigen

article

Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

scientific article published on 06 May 2015

Enhanced humoral and cell-mediated immune responses after immunization with trivalent influenza vaccine adjuvanted with cationic liposomes

scientific article

Epitope mapping of the immunodominant antigen TB10.4 and the two homologous proteins TB10.3 and TB12.9, which constitute a subfamily of the esat-6 gene family

scientific article

Evaluation of Mycobacterium tuberculosis--specific antibody responses in populations with different levels of exposure from Tanzania, Ethiopia, Brazil, and Denmark

scientific article published on 16 July 2007

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis

scientific article published on 20 January 2005

Ex Vivo Culture of Pharyngeal Arches to Study Heart and Muscle Progenitors and Their Niche

scientific article

Ex vivo cytokine mRNA levels correlate with changing clinical status of ethiopian TB patients and their contacts over time

scientific article

Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy

scientific article published on May 2005

Expression of apoptosis-related genes in an Ethiopian cohort study correlates with tuberculosis clinical status

scientific article published in January 2010

Failure of the Mycobacterium bovis BCG vaccine: some species of environmental mycobacteria block multiplication of BCG and induction of protective immunity to tuberculosis

scientific article

Failure to induce enhanced protection against tuberculosis by increasing T-cell-dependent interferon-gamma generation

scientific article

Fibronectin mediates mesendodermal cell fate decisions.

scientific article

First in humans: a new molecularly defined vaccine shows excellent safety and strong induction of long-lived Mycobacterium tuberculosis-specific Th1-cell like responses

scientific article published on December 2010

First-in-man open clinical trial of a combined rdESAT-6 and rCFP-10 tuberculosis specific skin test reagent

scientific article (publication date: 25 June 2010)

Gamma interferon responses induced by a panel of recombinant and purified mycobacterial antigens in healthy, non-mycobacterium bovis BCG-vaccinated Malawian young adults

scientific article

Genital tract lesions in sexually mature Göttingen minipigs during the initial stages of experimental vaginal infection with Chlamydia trachomatis serovar D.

scientific article

Genomic approach to identification of Mycobacterium bovis diagnostic antigens in cattle

scientific article

H1:IC31 vaccination is safe and induces long-lived TNF-α(+)IL-2(+)CD4 T cell responses in M. tuberculosis infected and uninfected adolescents: A randomized trial

scientific article

HCV p7 as a novel vaccine-target inducing multifunctional CD4+ and CD8+ T-cells targeting liver cells expressing the viral antigen

scientific article published on 01 October 2019

Healthy individuals that control a latent infection with Mycobacterium tuberculosis express high levels of Th1 cytokines and the IL-4 antagonist IL-4delta2.

scientific article published in June 2004

Heterologous Prime-Boost Combinations Highlight the Crucial Role of Adjuvant in Priming the Immune System.

scientific article

High Antigen Dose Is Detrimental to Post-Exposure Vaccine Protection against Tuberculosis

scientific article published in January 2017

High resolution electroelution of polyacrylamide gels for the purification of single proteins from Mycobacterium tuberculosis culture filtrate.

scientific article published on January 2000

High-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protection

scientific article

Higher human CD4 T cell response to novel Mycobacterium tuberculosis latency associated antigens Rv2660 and Rv2659 in latent infection compared with tuberculosis disease

scientific article

Host immunity to Mycobacterium tuberculosis and risk of tuberculosis: A longitudinal study among Greenlanders.

scientific article published on 27 October 2016

Host responses and antigens involved in protective immunity to Mycobacterium tuberculosis.

scientific article published on February 1997

Human B cells produce chemokine CXCL10 in the presence of Mycobacterium tuberculosis specific T cells

scientific article published on 22 October 2014

Human T cell responses to the ESAT-6 antigen from Mycobacterium tuberculosis.

scientific article

Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis

scientific article published on 13 June 2006

Human T-cell responses to the RD1-encoded protein TB27.4 (Rv3878) from Mycobacterium tuberculosis

scientific article published on December 2003

Human Th1 Cell Lines Recognize the Mycobacterium tuberculosis ESAT-6 Antigen and its Peptides in Association with Frequently Expressed HLA Class II Molecules

article

Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis

scientific article published on January 1998

Hypoxic response of Mycobacterium tuberculosis studied by metabolic labeling and proteome analysis of cellular and extracellular proteins

scientific journal article

Identification of CT521 as a frequent target of Th1 cells in patients with urogenital Chlamydia trachomatis infection

scientific article published on 22 September 2006

Identification of Rv0222 from RD4 as a novel serodiagnostic target for tuberculosis

scientific article published on 19 February 2008

Identifying protective Streptococcus pyogenes vaccine antigens recognized by both B and T cells in human adults and children

scientific article published on 25 February 2016

Immune Intervention Strategies against Tuberculosis

scholarly article

Immune responses to ESAT-6 and CFP-10 by FASCIA and multiplex technology for diagnosis of M. tuberculosis infection; IP-10 is a promising marker

scientific article

Immune responses to defined antigens of Mycobacterium bovis in cattle experimentally infected with Mycobacterium kansasii.

scientific article

Immune responses to the Mycobacterium tuberculosis-specific antigen ESAT-6 signal subclinical infection among contacts of tuberculosis patients

scientific article

Immunity by formulation design: induction of high CD8+ T-cell responses by poly(I:C) incorporated into the CAF01 adjuvant via a double emulsion method

scientific article

Immunity to mycobacteria with emphasis on tuberculosis: implications for rational design of an effective tuberculosis vaccine

scientific article published on January 1998

Immunocorrelates of CAF family adjuvants

scholarly article by Gabriel Kristian Pedersen et al published October 2018 in Seminars in Immunology

Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder

scientific article published on 24 April 2018

Immunological evaluation of novel Mycobacterium tuberculosis culture filtrate proteins

scientific article published on 01 February 1999

Immunological memory transferred with CD4 T cells specific for tuberculosis antigens Ag85B-TB10.4: persisting antigen enhances protection

scientific article

Improved long-term protection against Mycobacterium tuberculosis Beijing/W in mice after intra-dermal inoculation of recombinant BCG expressing latency associated antigens.

scientific article published on 24 August 2011

Improved response by co-targeting EGFR/EGFRvIII and Src family kinases in human cancer cells.

scientific article

Improved serodetection of Mycobacterium bovis infection in badgers (Meles meles) using multiantigen test formats

article

Incorporation of the TLR4 Agonist Monophosphoryl Lipid A Into the Bilayer of DDA/TDB Liposomes: Physico-Chemical Characterization and Induction of CD8+ T-Cell Responses In Vivo

article

Increased immunogenicity and protective efficacy of influenza M2e fused to a tetramerizing protein

scientific article

Inducing dose sparing with inactivated polio virus formulated in adjuvant CAF01.

scientific article

Induction of CD8 T Cells against a Novel Epitope in TB10.4: Correlation with Mycobacterial Virulence and the Presence of a Functional Region of Difference-1

scientific article published on 01 September 2007

Induction of CD8+ T-cell responses against subunit antigens by the novel cationic liposomal CAF09 adjuvant

scientific article published on 28 May 2014

Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C).

scientific article

Interaction between C-Tb and PPD given concomitantly in a split-body randomised controlled trial

scientific article published on 20 December 2018

Interleukin-6 regulates the phenotype of the immune response to a tuberculosis subunit vaccine

scientific article

Intramuscular Priming and Intranasal Boosting Induce Strong Genital Immunity Through Secretory IgA in Minipigs Infected with Chlamydia trachomatis

scientific article

Intrauterine inoculation of minipigs with Chlamydia trachomatis during diestrus establishes a longer lasting infection compared to vaginal inoculation during estrus.

scientific article published on 09 February 2017

Introducing the ESAT-6 free IGRA, a companion diagnostic for TB vaccines based on ESAT-6.

scientific article published on 07 April 2017

Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4 T cells from intestinal biopsies of Crohn's disease patients

scientific article

Large Particle Fluorescence-Activated Cell Sorting Enables High-Quality Single-Cell RNA Sequencing and Functional Analysis of Adult Cardiomyocytes

scientific article published on 15 August 2019

Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response

article

Liposomal vaccine delivery systems

scientific article published on 18 March 2011

Liposome delivery of Chlamydia muridarum major outer membrane protein primes a Th1 response that protects against genital chlamydial infection in a mouse model

scientific article published on September 2008

Liposome-based cationic adjuvant formulations (CAF): past, present, and future

scientific article published on January 2009

Liposomes act as stronger sub-unit vaccine adjuvants when compared to microspheres

scientific article published in August 2008

Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen

scientific article published on 26 October 2009

Local Th17/IgA immunity correlate with protection against intranasal infection with Streptococcus pyogenes

scientific article

Long-lived immune response to early secretory antigenic target 6 in individuals who had recovered from tuberculosis.

scientific article

Low Antigen Dose in Adjuvant-Based Vaccination Selectively Induces CD4 T Cells with Enhanced Functional Avidity and Protective Efficacy.

scientific article

MHC class II tetramer guided detection of Mycobacterium tuberculosis-specific CD4+ T cells in peripheral blood from patients with pulmonary tuberculosis.

scientific article published on May 2007

Mapping and identification ofMycobacterium tuberculosis proteins by two-dimensional gel electrophoresis, microsequencing and immunodetection

scholarly article by Ida Rosenkrands et al published 1 March 2000 in Electrophoresis

Mapping immune reactivity toward Rv2653 and Rv2654: two novel low-molecular-mass antigens found specifically in the Mycobacterium tuberculosis complex

scientific article published on 13 February 2004

Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers

scientific article published on 01 August 2019

Metabolic Profiling and Compound-Class Identification Reveal Alterations in Serum Triglyceride Levels in Mice Immunized with Human Vaccine Adjuvant Alum

scientific article published on 01 November 2019

Modulation of Primary Immune Response by Different Vaccine Adjuvants

scientific article published on 17 October 2016

Modulation of cell death by M. tuberculosis as a strategy for pathogen survival

scientific article published on 04 January 2011

Moving tuberculosis vaccines from theory to practice

scientific article published on 01 September 2019

Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity.

scientific article

Mucosal boosting of H56:CAF01 immunization promotes lung-localized T cells and an accelerated pulmonary response to Mycobacterium tuberculosis infection without enhancing vaccine protection

scientific article published on 13 February 2019

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

scientific article (publication date: July 2007)

Multiple epitopes from the Mycobacterium tuberculosis ESAT-6 antigen are recognized by antigen-specific human T cell lines.

scientific article published on June 2000

Mutations in Alström protein impair terminal differentiation of cardiomyocytes

scientific article published on 4 March 2014

NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01.

scientific article published on 23 July 2008

Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy ⬇️

scientific article published in January 2017

New tests for detection of Mycobacterium tuberculosis infection: sufficient to meet the WHO 2035 targets?

scientific article published on 22 August 2016

Non-canonical Notch signaling: emerging role and mechanism

scientific article published in May 2012

Non-clinical efficacy and safety of HyVac4:IC31 vaccine administered in a BCG prime-boost regimen

article published in 2010

Novel Vaccination Strategies Against Tuberculosis

scholarly article published 18 September 2017

Novel generation mycobacterial adjuvant based on liposome-encapsulated monomycoloyl glycerol from Mycobacterium bovis bacillus Calmette-Guérin.

scientific article published on 20 July 2009

Novel overlapping coding sequences in Chlamydia trachomatis

scientific article published on 13 October 2006

Novel vaccination strategies against tuberculosis.

scientific article

Oral vaccination with subunit vaccines protects animals against aerosol infection with Mycobacterium tuberculosis

scientific article

Overcoming the Neonatal Limitations of Inducing Germinal Centers through Liposome-Based Adjuvants Including C-Type Lectin Agonists Trehalose Dibehenate or Curdlan.

scientific article published on 28 February 2018

PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis

scientific article (publication date: July 2016)

PLGA microspheres for the delivery of a novel subunit TB vaccine

scientific article published on 01 May 2008

PO and ID BCG vaccination in humans induce distinct mucosal and systemic immune responses and CD4(+) T cell transcriptomal molecular signatures

scientific article published on 30 August 2017

PPE protein (Rv3873) from DNA segment RD1 of Mycobacterium tuberculosis: strong recognition of both specific T-cell epitopes and epitopes conserved within the PPE family

scientific article

Parasitic infection may be associated with discordant responses to QuantiFERON and tuberculin skin test in apparently healthy children and adolescents in a tuberculosis endemic setting, Ethiopia

scientific article

Parenteral Vaccination With a Tuberculosis Subunit Vaccine in Presence of Retinoic Acid Provides Early but Transient Protection to M. Tuberculosis Infection

scientific article published on 03 May 2019

Parenteral vaccination protects against transcervical infection with Chlamydia trachomatis and generate tissue-resident T cells post-challenge

scientific article published on 23 January 2020

Peptide-specific T helper cells identified by MHC class II tetramers differentiate into several subtypes upon immunization with CAF01 adjuvanted H56 tuberculosis vaccine formulation

scientific article published on 20 October 2015

Potential role for ESAT6 in dissemination of M. tuberculosis via human lung epithelial cells.

scientific article

Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors

scientific article

Precardiac organoids form two heart fields via Bmp/Wnt signaling

scientific article published in Nature Communications

Preparation of Culture Filtrate Proteins from Mycobacterium tuberculosis

scientific article

Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination.

scientific article published in July 2018

PrimaTB STAT-PAK assay, a novel, rapid lateral-flow test for tuberculosis in nonhuman primates

scientific article

Primary activation of antigen-specific naive CD4+ and CD8+ T cells following intranasal vaccination with recombinant bacteria

scientific article published on 06 October 2008

Proliferative responses to purified and fractionated Bordetella pertussis antigens in mice immunized with whole-cell pertussis vaccine

article

Prospective evaluation of a whole-blood test using Mycobacterium tuberculosis-specific antigens ESAT-6 and CFP-10 for diagnosis of active tuberculosis

scientific article

Prospects for a novel vaccine against tuberculosis

scientific article published in December 2005

Protection Against Chlamydia trachomatis Infection and Upper Genital Tract Pathological Changes by Vaccine-Promoted Neutralizing Antibodies Directed to the VD4 of the Major Outer Membrane Protein

scientific article published on 06 March 2015

Protection against Chlamydia promoted by a subunit vaccine (CTH1) compared with a primary intranasal infection in a mouse genital challenge model

scientific article

Protection and polyfunctional T cells induced by Ag85B-TB10.4/IC31 against Mycobacterium tuberculosis is highly dependent on the antigen dose

scientific article

Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6

scientific article published on 01 April 2005

Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of antigen 85b and esat-6.

scientific article

Protective CD4 T cells targeting cryptic epitopes of Mycobacterium tuberculosis resist infection-driven terminal differentiation

scientific article published on 26 February 2014

Protective Effect of Vaccine Promoted Neutralizing Antibodies against the Intracellular Pathogen Chlamydia trachomatis

scientific article published on 11 December 2017

Protective anti-mycobacterial T cell responses through exquisitein vivo activation of vaccine-targeted dendritic cells

article

Protective effect of a tuberculosis subunit vaccine based on a fusion of antigen 85B and ESAT-6 in the aerosol guinea pig model

scientific article published on October 2004

Protective efficacy against tuberculosis of ESAT-6 secreted by a live Salmonella typhimurium vaccine carrier strain and expressed by naked DNA.

scientific article published in July 2001

Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31.

scientific article published on 17 April 2006

Protein energy malnutrition during vaccination has limited influence on vaccine efficacy but abolishes immunity if administered during Mycobacterium tuberculosis infection

scientific article

Protein-protein interactions of proteins from the ESAT-6 family of Mycobacterium tuberculosis

scientific journal article

Proteomic profiling of Mycobacterium tuberculosis identifies nutrient-starvation-responsive toxin-antitoxin systems

scientific article published on 23 January 2013

Quality and Vaccine Efficacy of CD4+ T Cell Responses Directed to Dominant and Subdominant Epitopes in ESAT-6 from Mycobacterium tuberculosis

article

Quantitative Protein Profiling of Chlamydia trachomatis Growth Forms Reveals Defense Strategies Against Tryptophan Starvation

scientific article published on 26 October 2016

Randomised clinical trial investigating the specificity of a novel skin test (C-Tb) for diagnosis of M. tuberculosis infection

scientific article

Reactivation of tuberculosis during immunosuppressive treatment in a patient with a positive QuantiFERON-RD1 test.

scientific article published in January 2004

Recognition of ESAT-6 sequences by antibodies in sera of tuberculous nonhuman primates

scientific article published on January 2004

Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis

scientific article

Reprogramming the T Cell Response to Tuberculosis

scientific article

Responses of bovine WC1(+) gammadelta T cells to protein and nonprotein antigens of Mycobacterium bovis

scientific article published on November 2002

Restoration of mycobacterial antigen-induced proliferation and interferon-γ responses in peripheral blood mononuclear cells of tuberculosis patients upon effective chemotherapy

article

Risk of sensitization in healthy adults following repeated administration of rdESAT-6 skin test reagent by the Mantoux injection technique.

scientific article published on 8 February 2009

Robust antibody and CD8+ T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection.

scientific article published on 10 April 2017

Safety and efficacy of the C-Tb skin test to diagnose Mycobacterium tuberculosis infection, compared with an interferon γ release assay and the tuberculin skin test: a phase 3, double-blind, randomised, controlled trial.

scientific article

Safety and immunogenicity of H1/IC31®, an adjuvanted TB subunit vaccine, in HIV-infected adults with CD4+ lymphocyte counts greater than 350 cells/mm3: a phase II, multi-centre, double-blind, randomized, placebo-controlled trial

scientific article

Safety and immunogenicity of the chlamydia vaccine candidate CTH522 adjuvanted with CAF01 liposomes or aluminium hydroxide: a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial

scientific article published on 12 August 2019

Safety and immunogenicity of the novel H4:IC31 tuberculosis vaccine candidate in BCG-vaccinated adults: Two phase I dose escalation trials

scientific article

Sall1 transiently marks undifferentiated heart precursors and regulates their fate

scientific article published on 11 February 2016

Seasonal Influenza Split Vaccines Confer Partial Cross-Protection against Heterologous Influenza Virus in Ferrets When Combined with the CAF01 Adjuvant

scientific article published in January 2017

Secreted Antigens and Immune Responses to Mycobacterium tuberculosi s

article

Selecting the components for a safe and efficient tuberculosis subunit vaccine--recent progress and post-genomic insights

scientific article

Sensitivity of C-Tb: a novel RD-1-specific skin test for the diagnosis of tuberculosis infection

scientific article published on 17 December 2015

Signal regulatory protein alpha (SIRPalpha) cells in the adaptive response to ESAT-6/CFP-10 protein of tuberculous mycobacteria.

scientific article

Simultaneous Subcutaneous and Intranasal Administration of a CAF01-Adjuvanted Chlamydia Vaccine Elicits Elevated IgA and Protective Th1/Th17 Responses in the Genital Tract

scientific article

Simultaneous electroelution of whole SDS-polyacrylamide gels for the direct cellular analysis of complex protein mixtures

article

Site-Specific DC Surface Signatures Influence CD4+ T Cell Co-stimulation and Lung-Homing

scientific article published on 18 July 2019

Specific Delayed-Type Hypersensitivity Responses to ESAT-6 Identify Tuberculosis-Infected Cattle ⬇️

scientific article published on May 1, 2003

Specific T-cell epitopes for immunoassay-based diagnosis of Mycobacterium tuberculosis infection

scientific article

Specific immune-based diagnosis of tuberculosis

scientific article

Strategies to enhance immunogenicity of cDNA vaccine encoded antigens by modulation of antigen processing

scientific article published on September 2016

Subunit Vaccines: Distearoylphosphatidylcholine-Based Liposomes Entrapping Antigen Offer a Neutral Alternative to Dimethyldioctadecylammonium-Based Cationic Liposomes as an Adjuvant Delivery System

scientific article published on 10 December 2010

Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung

scientific article published on 24 August 2016

Synchronization of dendritic cell activation and antigen exposure is required for the induction of Th1/Th17 responses

scientific article

Synergistic Effect of Bacillus Calmette Guerin and a Tuberculosis Subunit Vaccine in Cationic Liposomes: Increased Immunogenicity and Protection

scientific article published on 01 March 2007

Syringe free vaccination with CAF01 Adjuvated Ag85B-ESAT-6 in Bioneedles provides strong and prolonged protection against tuberculosis

scientific article

Systematic Investigation of the Role of Surfactant Composition and Choice of oil: Design of a Nanoemulsion-Based Adjuvant Inducing Concomitant Humoral and CD4+ T-Cell Responses.

scientific article published on 17 May 2017

T Cells Primed by Live Mycobacteria Versus a Tuberculosis Subunit Vaccine Exhibit Distinct Functional Properties

scientific article published on 7 December 2017

T cell response to Mycobacterium tuberculosis.

scientific article

T-helper 1 and T-helper 2 adjuvants induce distinct differences in the magnitude, quality and kinetics of the early inflammatory response at the site of injection

scientific article

TB diagnosis in non-human primates: comparison of two interferon-gamma assays and the skin test for identification of Mycobacterium tuberculosis infection

scientific article published in July 2004

TB subunit vaccines--putting the pieces together

scientific article

TB vaccine strategies--what is needed to solve a complex problem?

scientific article

TB vaccines: current status and future perspectives

scientific article published on 07 April 2009

TB vaccines: progress and problems.

scientific article

TB vaccines; promoting rapid and durable protection in the lung

scientific article

Targeting the Mincle and TLR3 receptor using the dual agonist cationic adjuvant formulation 9 (CAF09) induces humoral and polyfunctional memory T cell responses in calves

scientific article published in PLoS ONE

Tbx6 Induces Nascent Mesoderm from Pluripotent Stem Cells and Temporally Controls Cardiac versus Somite Lineage Diversification

scientific article published on 6 September 2018

Testing the H56 Vaccine Delivered in 4 Different Adjuvants as a BCG-Booster in a Non-Human Primate Model of Tuberculosis

scientific article

The 6-kilodalton early secreted antigenic target-responsive, asymptomatic contacts of tuberculosis patients express elevated levels of interleukin-4 and reduced levels of gamma interferon

scientific article

The HyVac4 subunit vaccine efficiently boosts BCG-primed anti-mycobacterial protective immunity

scientific article (publication date: 2012)

The Influence of Remaining Live BCG Organisms in Vaccinated Mice on the Maintenance of Immunity to Tuberculosis

scientific article published on 01 September 2004

The Potential of the ESAT-6 Antigen Secreted by Virulent Mycobacteria for Specific Diagnosis of Tuberculosis

article

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

scientific article published on 29 February 2016

The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes

scientific article

The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile

scientific article published on 26 August 2016

The cationic liposomal adjuvants CAF01 and CAF09 formulated with the major outer membrane protein elicit robust protection in mice against a Chlamydia muridarum respiratory challenge

scientific article published on 23 February 2017

The combined CTA1-DD/ISCOMs vector is an effective intranasal adjuvant for boosting prior Mycobacterium bovis BCG immunity to Mycobacterium tuberculosis

scientific article published on 30 October 2006

The hunt for a global killer

scientific article

The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection

scientific article published on December 2011

The potential of recombinant antigens ESAT-6, MPT63 and mig for specific discrimination of Mycobacterium tuberculosis and M. avium infection

scientific article published on 25 April 2003

The prognosis of latent tuberculosis: can disease be predicted?

scientific article published on 5 April 2007

The success and failure of BCG - implications for a novel tuberculosis vaccine

scientific article

The supramolecular structure is decisive for the immunostimulatory properties of synthetic analogues of a mycobacterial lipid in vitro

The tuberculosis vaccine H4:IC31 is safe and induces a persistent polyfunctional CD4 T cell response in South African adults: A randomized controlled trial

scientific article published on 3 June 2015

Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy

scientific article published on 19 September 2019

Therapeutic vaccination using cationic liposome-adjuvanted HIV type 1 peptides representing HLA-supertype-restricted subdominant T cell epitopes: safety, immunogenicity, and feasibility in Guinea-Bissau

scientific article

Towards more accurate diagnosis of bovine tuberculosis using defined antigens.

scientific article

Towards the proteome of Mycobacterium tuberculosis

scholarly article by Ida Rosenkrands et al published November 2000 in Electrophoresis

Towards the proteome of Mycobacterium tuberculosis

scientific article published on 01 November 2000

Transcriptomics of the Vaccine Immune Response: Priming With Adjuvant Modulates Recall Innate Responses After Boosting.

scientific article published on 5 June 2018

Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin

scientific article

Trehalose preserves DDA/TDB liposomes and their adjuvant effect during freeze-drying

scientific article published on 13 May 2007

Tuberculin skin testing compared with T-cell responses to Mycobacterium tuberculosis-specific and nonspecific antigens for detection of latent infection in persons with recent tuberculosis contact

scientific article

Tuberculosis

Tuberculosis contacts but not patients have higher gamma interferon responses to ESAT-6 than do community controls in The Gambia.

scientific article

Tuberculosis in elephants: antibody responses to defined antigens of Mycobacterium tuberculosis, potential for early diagnosis, and monitoring of treatment

scientific article (publication date: July 2006)

Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells

scientific article published in June 2009

Tuberculosis subunit vaccine development: on the role of interferon-γ

article

Tuberculosis vaccine development

scientific article

Tuberculosis vaccine with high predicted population coverage and compatibility with modern diagnostics

scientific article published on 06 January 2014

Tuberculosis vaccines - an update.

scientific article

Tuberculosis vaccines--rethinking the current paradigm

scientific article

Tuberculosis vaccines: developmental work and the future.

scientific article

Type I IFN signalling is required for cationic adjuvant formulation (CAF)01-induced cellular immunity and mucosal priming

scientific article published on 11 November 2019

Unusual Self-Assembly of the Recombinant Chlamydia trachomatis Major Outer Membrane Protein (MOMP)-based Fusion Antigen CTH522 into Protein Nanoparticles

scientific article published on 13 February 2018

Use of ESAT-6 in the interferon-gamma test for diagnosis of bovine tuberculosis following skin testing.

scientific article

Use of ESAT‐6 and CFP‐10 Antigens for Diagnosis of Extrapulmonary Tuberculosis

scientific article published on 01 January 2001

Use of a neonatal rat system as a bioincubator to generate adult-like mature cardiomyocytes from human and mouse pluripotent stem cells.

scientific article published on 7 September 2017

Use of enzyme-linked immunospot assay with Mycobacterium tuberculosis-specific peptides for diagnosis of recent infection with M. tuberculosis after accidental laboratory exposure

scientific article published on March 2006

Use of mycobacterial peptides and recombinant proteins for the diagnosis of bovine tuberculosis in skin test-positive cattle

scientific article published on 01 November 2003

Vaccine strategies against latent tuberculosis infection

scientific article

Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responses

scientific article

Vaccine-induced th17 cells are maintained long-term postvaccination as a distinct and phenotypically stable memory subset

scientific article

Vaccines for tuberculosis: novel concepts and recent progress

scientific article

Vaccinia expression of Mycobacterium tuberculosis-secreted proteins: tissue plasminogen activator signal sequence enhances expression and immunogenicity of M. tuberculosis Ag85.

scientific article published on November 2000

Validation of the ALS assay in adult patients with culture confirmed pulmonary tuberculosis

scientific article

alpha,alpha'-trehalose 6,6'-dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying

scientific article published on 26 January 2008

β1-integrin is a cell-autonomous factor mediating the Numb pathway for cardiac progenitor maintenance.

scientific article published on 10 April 2018

Paulina is supported by:

About Paulina

Help