List of works - Karen I Hirsch-Ernst

A natural CYP2B6 TATA box polymorphism (-82T--> C) leading to enhanced transcription and relocation of the transcriptional start site.

scientific article

A two-faced vitamin : Folic acid - prevention or promotion of colon cancer?

scientific article published on 3 January 2017

Analysis of Acorus calamus chloroplast genome and its phylogenetic implications.

scientific article

Analysis of the Amborella trichopoda chloroplast genome sequence suggests that amborella is not a basal angiosperm.

scientific article published on 27 June 2003

Answer to the Letter to the Editor of Dr. Clouatre and Dr. Preuss

scientific article published in September 2017

Assessment of three approaches for regulatory decision making on pesticides with endocrine disrupting properties

scientific article published on 17 September 2014

Assessment strategies and decision criteria for pesticides with endocrine disrupting properties relevant to humans ⬇️

scientific article published on February 19, 2011

Cloning of human and rat ABCA5/Abca5 and detection of a human splice variant

scientific article

Combination effects of (tri)azole fungicides on hormone production and xenobiotic metabolism in a human placental cell line

scientific article

Contribution of mdr1b-type P-glycoprotein to okadaic acid resistance in rat pituitary GH3 cells

scientific article

Creatine and creatine forms intended for sports nutrition

scientific article published on 25 December 2016

Differential activation of the c-Ki-ras-2 proto-oncogene in human colorectal carcinoma

scientific article published on July 1, 1998

Differential induction of mRNA expression of cytochromes P450 (CYP2B1 and CYP1A1/2) by metyrapone in primary rat hepatocyte cultures

scientific article published on 01 October 1996

Expression and functional activity of P-glycoprotein in cultured hepatocytes from Oncorhynchus mykiss.

scientific article

Expression of c-fos and c-myc protooncogenes in an immortalized hepatocyte line harbouring SV40 T antigen and hGH as transgenes.

scientific article published on March 1993

Functional characterization of a -100_-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene

scientific article

High-performance liquid chromatographic method for simultaneous determination of [1-methyl-14C]caffeine and its eight major metabolites in rat urine

scientific article published on 01 April 1999

Increased expression of alpha6-integrin receptors and of mRNA encoding the putative 37 kDa laminin receptor precursor in pancreatic carcinoma

scientific article published on 01 September 1997

Induction of cytochrome P-4502B1-related mouse cytochrome P-450 and regulation of its expression by epidermal growth factor/transforming growth factor alpha in primary hepatocyte culture

scientific article published on 01 September 1995

Induction of mdr1b mRNA and P-glycoprotein expression by tumor necrosis factor alpha in primary rat hepatocyte cultures ⬇️

scientific article published on September 1, 1998

Inhibitors of mdr1-dependent transport activity delay accumulation of the mdr1 substrate rhodamine 123 in primary rat hepatocyte cultures.

scientific article

Low-level self-tolerance to arsenite in human HepG2 cells is associated with a depressed induction of micronuclei.

scientific article published on February 2002

Metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in primary cultures of rat alveolar type II cells.

scientific article published on February 2000

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver

scientific article published on 01 March 1998

Mimicry in primary rat hepatocyte cultures of the in vivo perivenous induction by phenobarbital of cytochrome P-450 2B1 mRNA: role of epidermal growth factor and perivenous oxygen tension.

scientific article published in July 1999

Mixture effects of azole fungicides on the adrenal gland in a broad dose range.

scientific article published on 25 April 2017

Modulation of P-glycoprotein and mdr1b mRNA expression by growth factors in primary rat hepatocyte culture.

scientific article

Molecular cDNA cloning and tissue distribution of mRNA encoding a novel ATP-binding cassette (ABC) half-transporter.

scientific article

Monitoring of cytochrome P-450 1A activity by determination of the urinary pattern of caffeine metabolites in Wistar and hyperbilirubinemic Gunn rats

scientific article published on 01 April 2000

PPARalpha-dependent induction of the energy homeostasis-regulating nuclear receptor NR1i3 (CAR) in rat hepatocytes: potential role in starvation adaptation

scientific article published on 20 November 2007

Phytochemical compounds in sport nutrition: Synephrine and hydroxycitric acid (HCA) as examples for evaluation of possible health risks

scientific article

Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures.

scientific article

Repression of phenobarbital-dependent CYP2B1 mRNA induction by reactive oxygen species in primary rat hepatocyte cultures.

scientific article

Risk assessment of synephrine in dietary supplements

scientific article published on 5 January 2017

Safety Aspects of the Use of Quercetin as a Dietary Supplement.

scientific article

Subcellular localization of rat Abca5, a rat ATP-binding-cassette transporter expressed in Leydig cells, and characterization of its splice variant apparently encoding a half-transporter

scientific journal article

Synergistic acceleration of thyroid hormone degradation by phenobarbital and the PPAR alpha agonist WY14643 in rat hepatocytes.

scientific article published on 22 July 2009

The Chloroplast Genome of Nymphaea alba: Whole-Genome Analyses and the Problem of Identifying the Most Basal Angiosperm

scientific article

The cyclooxygenase system participates in functional mdr1b overexpression in primary rat hepatocyte cultures

scientific article

The role of prostaglandin E receptor-dependent signaling via cAMP in Mdr1b gene activation in primary rat hepatocyte cultures

scientific article published on 13 January 2006

Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine.

scientific article

Transcriptional regulation of CYP2B1 induction in primary rat hepatocyte cultures: repression by epidermal growth factor is mediated via a distal enhancer region.

scientific article

Vesicular localization of the rat ATP-binding cassette half-transporter rAbcb6.

scientific article published on 26 December 2007

[Food Supplements - Considerations in Medical Practice]

scientific article published on 04 May 2018

List of works by Karen I Hirsch-Ernst

A natural CYP2B6 TATA box polymorphism (-82T--> C) leading to enhanced transcription and relocation of the transcriptional start site.

A two-faced vitamin : Folic acid - prevention or promotion of colon cancer?

Analysis of Acorus calamus chloroplast genome and its phylogenetic implications.

Analysis of the Amborella trichopoda chloroplast genome sequence suggests that amborella is not a basal angiosperm.

Answer to the Letter to the Editor of Dr. Clouatre and Dr. Preuss

Assessment of three approaches for regulatory decision making on pesticides with endocrine disrupting properties

Assessment strategies and decision criteria for pesticides with endocrine disrupting properties relevant to humans ⬇️

Cloning of human and rat ABCA5/Abca5 and detection of a human splice variant

Combination effects of (tri)azole fungicides on hormone production and xenobiotic metabolism in a human placental cell line

Contribution of mdr1b-type P-glycoprotein to okadaic acid resistance in rat pituitary GH3 cells

Creatine and creatine forms intended for sports nutrition

Differential activation of the c-Ki-ras-2 proto-oncogene in human colorectal carcinoma

Differential induction of mRNA expression of cytochromes P450 (CYP2B1 and CYP1A1/2) by metyrapone in primary rat hepatocyte cultures

Expression and functional activity of P-glycoprotein in cultured hepatocytes from Oncorhynchus mykiss.

Expression of c-fos and c-myc protooncogenes in an immortalized hepatocyte line harbouring SV40 T antigen and hGH as transgenes.

Functional characterization of a -100_-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene

High-performance liquid chromatographic method for simultaneous determination of [1-methyl-14C]caffeine and its eight major metabolites in rat urine

Increased expression of alpha6-integrin receptors and of mRNA encoding the putative 37 kDa laminin receptor precursor in pancreatic carcinoma

Induction of cytochrome P-4502B1-related mouse cytochrome P-450 and regulation of its expression by epidermal growth factor/transforming growth factor alpha in primary hepatocyte culture

Induction of mdr1b mRNA and P-glycoprotein expression by tumor necrosis factor alpha in primary rat hepatocyte cultures ⬇️

Inhibitors of mdr1-dependent transport activity delay accumulation of the mdr1 substrate rhodamine 123 in primary rat hepatocyte cultures.

Low-level self-tolerance to arsenite in human HepG2 cells is associated with a depressed induction of micronuclei.

Metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in primary cultures of rat alveolar type II cells.

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver

Mimicry in primary rat hepatocyte cultures of the in vivo perivenous induction by phenobarbital of cytochrome P-450 2B1 mRNA: role of epidermal growth factor and perivenous oxygen tension.

Mixture effects of azole fungicides on the adrenal gland in a broad dose range.

Modulation of P-glycoprotein and mdr1b mRNA expression by growth factors in primary rat hepatocyte culture.

Molecular cDNA cloning and tissue distribution of mRNA encoding a novel ATP-binding cassette (ABC) half-transporter.

Monitoring of cytochrome P-450 1A activity by determination of the urinary pattern of caffeine metabolites in Wistar and hyperbilirubinemic Gunn rats

PPARalpha-dependent induction of the energy homeostasis-regulating nuclear receptor NR1i3 (CAR) in rat hepatocytes: potential role in starvation adaptation

Phytochemical compounds in sport nutrition: Synephrine and hydroxycitric acid (HCA) as examples for evaluation of possible health risks

Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures.

Repression of phenobarbital-dependent CYP2B1 mRNA induction by reactive oxygen species in primary rat hepatocyte cultures.

Risk assessment of synephrine in dietary supplements

Safety Aspects of the Use of Quercetin as a Dietary Supplement.

Subcellular localization of rat Abca5, a rat ATP-binding-cassette transporter expressed in Leydig cells, and characterization of its splice variant apparently encoding a half-transporter

Synergistic acceleration of thyroid hormone degradation by phenobarbital and the PPAR alpha agonist WY14643 in rat hepatocytes.

The Chloroplast Genome of Nymphaea alba: Whole-Genome Analyses and the Problem of Identifying the Most Basal Angiosperm

The cyclooxygenase system participates in functional mdr1b overexpression in primary rat hepatocyte cultures

The role of prostaglandin E receptor-dependent signaling via cAMP in Mdr1b gene activation in primary rat hepatocyte cultures

Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine.

Transcriptional regulation of CYP2B1 induction in primary rat hepatocyte cultures: repression by epidermal growth factor is mediated via a distal enhancer region.

Vesicular localization of the rat ATP-binding cassette half-transporter rAbcb6.

[Food Supplements - Considerations in Medical Practice]