List of works - Alasdair Ivens

'Oming in on schistosomes: prospects and limitations for post-genomics

scientific article published on 13 November 2006

11p15.5-specific libraries for identification of potential gene sequences involved in Beckwith-Wiedemann syndrome and tumorigenesis.

scientific article

A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation

scientific article published on 21 March 2011

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

scientific article published on 24 April 2015

A gene expression atlas of the domestic pig

scientific article

A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development

scientific article published on 11 October 2018

A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation

scientific article published on 21 September 2020

A new Dictyostelium prestalk cell sub-type

scientific article

A re-annotation of the Saccharomyces cerevisiae genome.

scientific article

A software framework for microarray and gene expression object model (MAGE-OM) array design annotation

scientific article

Advances in schistosome genomics.

scientific article published on April 2004

Altered patterns of gene expression underlying the enhanced immunogenicity of radiation-attenuated schistosomes

scientific article

Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa

scientific article published on January 2007

An integrated physical map of 210 markers assigned to the short arm of human chromosome 11.

scientific article published on June 1994

Analysis of the hypervariable region of the Salmonella enterica genome associated with tRNA(leuX).

scientific article published on April 2005

Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses

scientific article

Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology.

scientific article published on 22 November 2016

Boudicca, a retrovirus-like long terminal repeat retrotransposon from the genome of the human blood fluke Schistosoma mansoni.

scientific article published in June 2003

Characterization of the genomes of a diverse collection of Salmonella enterica serovar Typhimurium definitive phage type 104

scientific article published on 10 October 2008

Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites.

scientific article published on December 2010

Choice of bacterial growth medium alters the transcriptome and phenotype of Salmonella enterica Serovar Typhimurium

scientific article

Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of Klebsiella pneumoniae Carbapenemase-Carrying Plasmids.

scientific article published on 24 April 2018

Clinically relevant mutant DNA gyrase alters supercoiling, changes the transcriptome, and confers multidrug resistance.

scientific article published on 23 July 2013

Combinatorial communication in bacteria: implications for the origins of linguistic generativity

scientific article

Combinatorial quorum sensing allows bacteria to resolve their social and physical environment

scientific article published on 04 March 2014

Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds

scientific article published on 7 July 2009

Comparative genomic analysis of three Leishmania species that cause diverse human disease

scientific article

Comparative genomics of trypanosomatid parasitic protozoa

scientific article (publication date: 15 July 2005)

Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection.

scientific article published on 26 June 2003

Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase.

scientific article published on 15 February 2006

Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains.

scientific article

Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children

scientific article

Differentially expressed Leishmania major gp63 genes encode cell surface leishmanolysin with distinct signals for glycosylphosphatidylinositol attachment.

scientific article published in May 1998

Ectopic recombination of a malaria var gene during mitosis associated with an altered var switch rate.

scientific article published on 21 April 2009

Epigenetic silencing of Plasmodium falciparum genes linked to erythrocyte invasion ⬇️

scientific article

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

scientific article

Exposure of Escherichia coli and Salmonella enterica serovar Typhimurium to triclosan induces a species-specific response, including drug detoxification.

scientific article published on 16 September 2009

Expression profiling of the Leishmania life cycle: cDNA arrays identify developmentally regulated genes present but not annotated in the genome

scientific article published in July 2004

Extracellular Onchocerca-derived small RNAs in host nodules and blood

scientific article

Fasciola hepatica expresses multiple alpha- and beta-tubulin isotypes.

scientific article published on 14 February 2008

From genomes to vaccines: Leishmania as a model

scientific article

Functional Websites for Parasite Genome Projects

scientific article published on 01 March 2000

Gene copy number variation throughout the Plasmodium falciparum genome

scientific article

Gene synteny and evolution of genome architecture in trypanosomatids

article

Genetic diversity amongst isolates of Neospora caninum, and the development of a multiplex assay for the detection of distinct strains.

scientific article published on June 2009

Genetic nomenclature for Trypanosoma and Leishmania.

scientific article

Genome and phylogenetic analyses of trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty

scientific article published in January 2015

Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes

scientific article published on 22 May 2007

Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum

scientific article

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei.

scientific article

Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei

scientific article

Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium

scientific article

Genomic analysis of the causative agents of coccidiosis in domestic chickens

scientific article

Genomic and phenotypic variation in epidemic-spanning Salmonella enterica serovar Enteritidis isolates

scientific article

High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.

scientific article published on 17 January 2014

Hurrah for genome projects!

scientific article published on 01 August 2000

Identification of a human neonatal immune-metabolic network associated with bacterial infection

scientific article

Identification of core and variable components of the Salmonella enterica subspecies I genome by microarray.

scientific article published on December 2005

Identification of genetic and phenotypic differences associated with prevalent and non-prevalent Salmonella Enteritidis phage types: analysis of variation in amino acid transport.

scientific article published on 2 July 2009

Integration of tools and resources for display and analysis of genomic data for protozoan parasites

scientific article

Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium.

scientific article

Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite.

scientific article published in August 2002

Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes

scientific article

Leishmania major chromosome 3 contains two long convergent polycistronic gene clusters separated by a tRNA gene

scientific article

Leishmania major: histone H1 gene expression from the sw3 locus.

scientific article

Linkage of an X-chromosome cleft palate gene

scientific article published in Nature

Microarray analyses of mouse responses to infection by Neospora caninum identifies disease associated cellular pathways in the host response ⬇️

scientific article published on September 15, 2010

Microarray analysis identifies genes preferentially expressed in the lung schistosomulum of Schistosoma mansoni

scientific article published on 15 November 2005

Microarray-based comparative genomic analyses of the human malaria parasite Plasmodium falciparum using Affymetrix arrays

scientific article published on 8 September 2005

Molecular cloning and characterization of two new isoforms of the protein kinase A catalytic subunit from the human parasite Leishmania.

scientific article published on April 2002

Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome rearrangement breakpoints and subchromosomal transferable fragments

scientific article

NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway.

scientific article published on 14 April 2015

Parasite-derived microRNAs in host serum as novel biomarkers of helminth infection

scientific article published on 20 February 2014

Polymorphic dinucleotide repeat at the DXS3 locus

scientific article published on September 1991

Prophage sequences defining hot spots of genome variation in Salmonella enterica serovar Typhimurium can be used to discriminate between field isolates

scientific article published on 23 May 2007

Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts

scientific article

Quantitative Analysis of MicroRNAs in Vaccinia virus Infection Reveals Diversity in Their Susceptibility to Modification and Suppression.

scientific article published on 10 July 2015

RamA, a member of the AraC/XylS family, influences both virulence and efflux in Salmonella enterica serovar Typhimurium.

scientific article

Regulation of Trypanosoma brucei Total and Polysomal mRNA during Development within Its Mammalian Host.

scientific article

Reports from the Cutting Edge of Parasitic Genome Analysis

scientific article published on 01 November 1999

Salmonella Typhi sense host neuroendocrine stress hormones and release the toxin haemolysin E

scientific article

Secondary DNA structure analysis of the coding strand switch regions of five Leishmania major Friedlin chromosomes

scientific article published on 01 October 2001

Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity.

scientific article

Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization

scientific article

Sex determination in the social amoeba Dictyostelium discoideum

scientific article

Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum

scientific article (publication date: 14 April 2009)

SrfB, a member of the Serum Response Factor family of transcription factors, regulates starvation response and early development in Dictyostelium.

scientific article published on 31 January 2008

Structure and sequence of the human homeobox gene HOX7.

scientific article published in November 1991

Targets downstream of Cdk8 in Dictyostelium development

scientific article

The Complete Chromosomal Organization of the Reference Strain of the Leishmania Genome Project, L. major `Friedlin'

scientific article published in August 1998

The Eimeria genome projects: a sequence of events.

scientific article published on May 2004

The Leishmania genome comes of Age.

scientific article

The TCA cycle is not required for selection or survival of multidrug-resistant Salmonella

scientific article published on 20 December 2011

The amoebal MAP kinase response to Legionella pneumophila is regulated by DupA

scientific article published on September 2009

The generation of ordered sets of cosmid DNA clones from human chromosome region 11p

scientific article published on 01 May 1992

The genome of the blood fluke Schistosoma mansoni

scientific article

The genome of the kinetoplastid parasite, Leishmania major

scientific article

The genome of the simian and human malaria parasite Plasmodium knowlesi

scientific article

The global consequence of disruption of the AcrAB-TolC efflux pump in Salmonella enterica includes reduced expression of SPI-1 and other attributes required to infect the host.

scientific article published on May 2009

The human homeobox gene HOX7 maps to chromosome 4p16.1 and may be implicated in Wolf-Hirschhorn syndrome.

scientific article

The role of prophage-like elements in the diversity of Salmonella enterica serovars

scientific article published in May 2004

The transcriptional response of Caenorhabditis elegans to Ivermectin exposure identifies novel genes involved in the response to reduced food intake

scientific article

Two novel Src homology 2 domain proteins interact to regulate dictyostelium gene expression during growth and early development

scientific article

Two novel Src homology 2 domain proteins interact to regulateDictyosteliumgene expression during growth and early development

scientific article published in Journal of Biological Chemistry

Unravelling the Leishmania genome.

scientific article published on December 1996

Whole blood gene expression profiling of neonates with confirmed bacterial sepsis

scientific article

Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum

scientific article published on 22 April 2008

X-linked cleft palate: the gene is localized between polymorphic DNA markers DXYS12 and DXS17

scientific article published on 01 April 1988

tRNAs in Trypanosoma brucei: genomic organization, expression, and mitochondrial import

scientific article

List of works by Alasdair Ivens

'Oming in on schistosomes: prospects and limitations for post-genomics

11p15.5-specific libraries for identification of potential gene sequences involved in Beckwith-Wiedemann syndrome and tumorigenesis.

A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

A gene expression atlas of the domestic pig

A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development

A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation

A new Dictyostelium prestalk cell sub-type

A re-annotation of the Saccharomyces cerevisiae genome.

A software framework for microarray and gene expression object model (MAGE-OM) array design annotation

Advances in schistosome genomics.

Altered patterns of gene expression underlying the enhanced immunogenicity of radiation-attenuated schistosomes

Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa

An integrated physical map of 210 markers assigned to the short arm of human chromosome 11.

Analysis of the hypervariable region of the Salmonella enterica genome associated with tRNA(leuX).

Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses

Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology.

Boudicca, a retrovirus-like long terminal repeat retrotransposon from the genome of the human blood fluke Schistosoma mansoni.

Characterization of the genomes of a diverse collection of Salmonella enterica serovar Typhimurium definitive phage type 104

Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites.

Choice of bacterial growth medium alters the transcriptome and phenotype of Salmonella enterica Serovar Typhimurium

Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of Klebsiella pneumoniae Carbapenemase-Carrying Plasmids.

Clinically relevant mutant DNA gyrase alters supercoiling, changes the transcriptome, and confers multidrug resistance.

Combinatorial communication in bacteria: implications for the origins of linguistic generativity

Combinatorial quorum sensing allows bacteria to resolve their social and physical environment

Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds

Comparative genomic analysis of three Leishmania species that cause diverse human disease

Comparative genomics of trypanosomatid parasitic protozoa

Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection.

Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase.

Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains.

Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children

Differentially expressed Leishmania major gp63 genes encode cell surface leishmanolysin with distinct signals for glycosylphosphatidylinositol attachment.

Ectopic recombination of a malaria var gene during mitosis associated with an altered var switch rate.

Epigenetic silencing of Plasmodium falciparum genes linked to erythrocyte invasion ⬇️

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

Exposure of Escherichia coli and Salmonella enterica serovar Typhimurium to triclosan induces a species-specific response, including drug detoxification.

Expression profiling of the Leishmania life cycle: cDNA arrays identify developmentally regulated genes present but not annotated in the genome

Extracellular Onchocerca-derived small RNAs in host nodules and blood

Fasciola hepatica expresses multiple alpha- and beta-tubulin isotypes.

From genomes to vaccines: Leishmania as a model

Functional Websites for Parasite Genome Projects

Gene copy number variation throughout the Plasmodium falciparum genome

Gene synteny and evolution of genome architecture in trypanosomatids

Genetic diversity amongst isolates of Neospora caninum, and the development of a multiplex assay for the detection of distinct strains.

Genetic nomenclature for Trypanosoma and Leishmania.

Genome and phylogenetic analyses of trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty

Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes

Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei.

Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei

Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium

Genomic analysis of the causative agents of coccidiosis in domestic chickens

Genomic and phenotypic variation in epidemic-spanning Salmonella enterica serovar Enteritidis isolates

High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.

Hurrah for genome projects!

Identification of a human neonatal immune-metabolic network associated with bacterial infection

Identification of core and variable components of the Salmonella enterica subspecies I genome by microarray.

Identification of genetic and phenotypic differences associated with prevalent and non-prevalent Salmonella Enteritidis phage types: analysis of variation in amino acid transport.

Integration of tools and resources for display and analysis of genomic data for protozoan parasites

Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium.

Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite.

Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes

Leishmania major chromosome 3 contains two long convergent polycistronic gene clusters separated by a tRNA gene

Leishmania major: histone H1 gene expression from the sw3 locus.

Linkage of an X-chromosome cleft palate gene

Microarray analyses of mouse responses to infection by Neospora caninum identifies disease associated cellular pathways in the host response ⬇️

Microarray analysis identifies genes preferentially expressed in the lung schistosomulum of Schistosoma mansoni

Microarray-based comparative genomic analyses of the human malaria parasite Plasmodium falciparum using Affymetrix arrays

Molecular cloning and characterization of two new isoforms of the protein kinase A catalytic subunit from the human parasite Leishmania.

Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome rearrangement breakpoints and subchromosomal transferable fragments

NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway.

Parasite-derived microRNAs in host serum as novel biomarkers of helminth infection

Polymorphic dinucleotide repeat at the DXS3 locus

Prophage sequences defining hot spots of genome variation in Salmonella enterica serovar Typhimurium can be used to discriminate between field isolates

Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts

Quantitative Analysis of MicroRNAs in Vaccinia virus Infection Reveals Diversity in Their Susceptibility to Modification and Suppression.

RamA, a member of the AraC/XylS family, influences both virulence and efflux in Salmonella enterica serovar Typhimurium.

Regulation of Trypanosoma brucei Total and Polysomal mRNA during Development within Its Mammalian Host.