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List of works by Pablo Huertas

A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.

scientific article

ALC1/eIF4A1-mediated regulation of CtIP mRNA stability controls DNA end resection

scientific article published on 11 May 2020

An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.

scientific article

BRCA1 accelerates CtIP-mediated DNA-end resection

scientific article published on 9 October 2014

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis

scientific article published in 2024

CDK targets Sae2 to control DNA-end resection and homologous recombination

scientific article

Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.

scientific article

Controlling the balance between chromosome break repair pathways

Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination ⬇️

scientific article published on September 1, 2003

CtIP -mediated alternative mRNA splicing finetunes the DNA damage response

scientific article published on 09 December 2020

CtIP Mutations Cause Seckel and Jawad Syndromes

scientific article

CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells

scientific article

DNA end resection requires constitutive sumoylation of CtIP by CBX4.

scientific article published on 24 July 2017

DNA resection in eukaryotes: deciding how to fix the break

scientific article

Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1.

scientific article published on 6 March 2018

Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity

scientific article

EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks

scientific article published on 13 May 2019

Human CtIP mediates cell cycle control of DNA end resection and double strand break repair

scientific journal article

Importance of hydrophobic interactions in the single-chained cationic surfactant-DNA complexation

scientific article published on 15 March 2018

Interdependence between Transcription and mRNP Processing and Export, and Its Impact on Genetic Stability

scientific article published on 01 June 2005

MRGBP, a member of the NuA4 complex, inhibits DNA double strand break repair

scientific article published on 22 December 2020

Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material

scientific article published on 25 May 2020

Mitotic recombination in Saccharomyces cerevisiae

scientific article

Multiple roles of the splicing complex SF3B in DNA end resection and homologous recombination

Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice

scientific article

New tools to study DNA double-strand break repair pathway choice

scientific article

Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair

scientific article published on 14 December 2017

PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks

scientific article published on 30 March 2020

Preparation of a radiobiology beam line at the 18 MeV proton cyclotron facility at CNA

scientific article published on 07 May 2020

Prognostic value of CtIP/RBBP8 expression in breast cancer

scientific article published on 03 October 2013

Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae. New insights into transcription-associated recombination.

scientific article published on October 2003

Single Molecule Analysis of Resection Tracks.

scientific article published in January 2018

Speed matters: How subtle changes in DNA end resection rate affect repair.

scientific article published on 6 May 2015

Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox

scientific article published on 21 February 2020

Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer

scientific article

The COP9 signalosome is vital for timely repair of DNA double-strand breaks

scientific article published on 8 April 2015

The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures

The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures

scientific article published on 01 December 2018

The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.

scientific article

The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.

scientific article published in March 2018

The role of RNA and RNA-related proteins in the regulation of DNA double strand break repair pathway choice

scientific article published on 08 July 2019

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

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