List of works - Kevin J McElwee

A "hair-raising" history of alopecia areata

scientific article published on 05 February 2020

A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma

scientific article

Abnormal interactions between perifollicular mast cells and CD8+ T-cells may contribute to the pathogenesis of alopecia areata

scientific article

Allergy promotes alopecia areata in a subset of patients

scientific article published on 03 September 2019

Allergy to dust mites may contribute to early onset and severity of alopecia areata

scientific article published on 23 September 2014

Alopecia Areata Susceptibility in Rodent Models ⬇️

scientific article published on October 1, 2003

Alopecia Areata is Associated with Increased Expression of Heart Disease Biomarker Cardiac Troponin I

scientific article published on 01 August 2018

Alopecia areata

scientific article published on 01 January 2008

Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss.

scientific article published in November 2003

Alopecia areata in humans and other mammalian species.

scientific article published in May 1995

Alopecia areata update: part II. Treatment

scientific article

Alopecia areata versus juvenile alopecia in C3H/HeJ mice: tools to dissect the role of inflammation in focal alopecia

scientific article published on 01 August 1999

Alopecia areata-like hair loss in C3H/HeJ mice and DEBR rats can be reversed using topical diphencyprone

scientific article published on 01 December 1999

Alopecia areata: pathogenesis and potential for therapy

scientific article published on 20 June 2006

Animal Models for Alopecia Areata: What and Where?

scientific article

Apoptosis resistance in peripheral blood lymphocytes of alopecia areata patients.

scientific article published in November 2004

Assessment of hair density and caliber in Caucasian and Asian female subjects with female pattern hair loss by using the Folliscope.

scientific article published in January 2012

Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase-I Study

scientific article published on 11 September 2019

Benefit of different concentrations of intralesional triamcinolone acetonide in alopecia areata: An intrasubject pilot study

scientific article published on 01 August 2015

Biology of the hair follicle and mechanisms of nonscarring and scarring alopecia.

scientific article published on June 2015

CXCR3 ligands promote expression of functional indoleamine 2,3-dioxygenase in basal cell carcinoma keratinocytes.

scientific article

CXCR3/ligands are significantly involved in the tumorigenesis of basal cell carcinomas

scientific article

Changes in serum free testosterone, sleep patterns, and 5-alpha-reductase type I activity influence changes in sebum excretion in female subjects.

scientific article published on 28 August 2014

Chronic delayed-type hypersensitivity reaction as a means to treat alopecia areata.

scientific article published in March 2004

Comparison of alopecia areata in human and nonhuman mammalian species.

scientific article published in January 1998

Cultured peribulbar dermal sheath cells can induce hair follicle development and contribute to the dermal sheath and dermal papilla

scientific article published on 01 December 2003

Current and potential agents for the treatment of alopecia areata

scientific article

Deficiency in nucleotide excision repair family gene activity, especially ERCC3, is associated with non-pigmented hair fiber growth

scientific article

Development of autoimmune hair loss disease alopecia areata is associated with cardiac dysfunction in C3H/HeJ mice

scientific article

Diagnosis and management of primary cicatricial alopecia: part II.

scientific article published on March 2008

Dietary soy oil content and soy-derived phytoestrogen genistein increase resistance to alopecia areata onset in C3H/HeJ mice.

scientific article published in February 2003

Endogenous retinoids in the pathogenesis of alopecia areata

scientific article

Etiology of cicatricial alopecias: a basic science point of view.

scientific article published on July 2008

Etiopathogenesis of alopecia areata: Why do our patients get it?

scientific article published on 01 May 2011

Examining the relationship between alopecia areata, androgenetic alopecia, and emotional intelligence

scientific article published in January 2013

Experimental and early investigational drugs for androgenetic alopecia

scientific article

Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts

scientific article published on 01 November 1998

Fas-deficient C3.MRL-Tnfrsf6(lpr) mice and Fas ligand-deficient C3H/HeJ-Tnfsf6(gld) mice are relatively resistant to the induction of alopecia areata by grafting of alopecia areata-affected skin from C3H/HeJ mice.

scientific article

Fibroblast cell-based therapy prevents induction of alopecia areata in an experimental model

scientific article published on 05 June 2018

Frontal fibrosing alopecia: a retrospective clinical review of 62 patients with treatment outcome and long-term follow-up.

scientific article published on 16 April 2014

Genetic susceptibility and severity of alopecia areata in human and animal models.

scientific article

Growth factor concentrations in platelet-rich plasma for androgenetic alopecia: An intra-subject, randomized, blinded, placebo-controlled, pilot study

scientific article published on 07 February 2020

Hair follicle autoantibodies in DEBR rat sera.

scientific article published in May 1995

Hair follicle dermal sheath derived cells improve islet allograft survival without systemic immunosuppression.

scientific article published on 27 April 2015

Hair follicle immune privilege and its collapse in alopecia areata

scientific article published on 18 July 2020

Hair follicle mesenchyme-associated PD-L1 regulates T-cell activation induced apoptosis: a potential mechanism of immune privilege.

scientific article published on 4 September 2013

Hair follicles from alopecia areata patients exhibit alterations in immune privilege-associated gene expression in advance of hair loss

scientific article published on 08 July 2010

High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma

scientific article

Identification of Autoantigen Epitopes in Alopecia Areata.

scientific article

Immunotherapy of melanoma: present options and future promises.

scientific article

In vivo depletion of CD8+ T cells restores hair growth in the DEBR model for alopecia areata

scientific article published on 01 August 1996

Increased expression of TLR7 and TLR9 in alopecia areata

scientific article published on 14 October 2019

Increased expression of neuropilin 1 in melanoma progression and its prognostic significance in patients with melanoma.

scientific article published on 7 May 2015

Integrin β6-deficient mice show enhanced keratinocyte proliferation and retarded hair follicle regression after depilation

scientific article published on 24 November 2011

Interferon-gamma-deficient mice are resistant to the development of alopecia areata.

scientific article

Interleukin-10-deficient mice are less susceptible to the induction of alopecia areata

scientific article published on 01 October 2002

Interleukin-6 cytokine family member oncostatin M is a hair-follicle-expressed factor with hair growth inhibitory properties

scientific article published on 02 November 2007

Label-free identification and characterization of murine hair follicle stem cells located in thin tissue sections with Raman micro-spectroscopy.

scientific article

Lichen planopilaris and pseudopelade of Brocq involve distinct disease associated gene expression patterns by microarray

scientific article published on 22 November 2009

Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis.

scientific article

Macrophage-stimulating protein promotes hair growth ex vivo and induces anagen from telogen stage hair follicles in vivo.

scientific article published in July 2004

Major locus on mouse chromosome 17 and minor locus on chromosome 9 are linked with alopecia areata in C3H/HeJ mice

scientific article published on 01 May 2003

Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata.

scientific article published in December 2001

Murine cytomegalovirus is not associated with alopecia areata in C3H/HeJ mice

scientific article published on 01 June 1998

New developments in hair research

scientific article published on 01 March 2020

Non-scarring patchy alopecia in patients with systemic lupus erythematosus differs from that of alopecia areata

scientific article published on 16 October 2013

Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis.

scientific article published on 02 February 2017

Partial restoration of hair growth in the DEBR model for Alopecia areata after in vivo depletion of CD4+ T cells

scientific article published on 01 March 1999

Prognostic Significance of Nuclear Phospho-ATM Expression in Melanoma

scientific article published on 14 August 2015

Promising therapies for treating and/or preventing androgenic alopecia

scientific article published on June 1, 2012

Ratite oils promote keratinocyte cell growth and inhibit leukocyte activation

scientific article published on 27 July 2015

Reduced Expression of Interleukin-2 Decreases the Frequency of Alopecia Areata Onset in C3H/HeJ Mice

article

Reduced expression of SRY-box containing gene 17 correlates with an unfavorable melanoma patient survival.

scientific article published on 8 October 2014

Regulatory T cells in autoimmune diseases and their potential.

scientific article published in December 2005

Resistance to alopecia areata in C3H/HeJ mice is associated with increased expression of regulatory cytokines and a failure to recruit CD4+ and CD8+ cells.

scientific article

Sequential cyclic changes of hair roots revealed by dermoscopy demonstrate a progressive mechanism of diffuse alopecia areata over time

article

Serum level of IL-4 predicts response to topical immunotherapy with diphenylcyclopropenone in alopecia areata

scientific article published on 29 August 2018

Somatostatin expression in human hair follicles and its potential role in immune privilege

scientific article published on 31 January 2013

Spontaneous alopecia areata-like hair loss in one congenic and seven inbred laboratory mouse strains

scientific article published on 01 December 1999

Stage-specific prognostic biomarkers in melanoma

scientific article published on February 2015

Successful treatment of alopecia areata-like hair loss with the contact sensitizer squaric acid dibutylester (SADBE) in C3H/HeJ mice

scientific article published on 01 July 1999

The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results.

scientific article published on October 2008

The DEBR rat, alopecia areata and autoantibodies to the hair follicle

scientific article published on 01 January 1996

The basic science of hair biology: what are the causal mechanisms for the disordered hair follicle?

scientific article published on 24 September 2012

The functional relevance of the type 1 cytokines IFN-gamma and IL-2 in alopecia areata of C3H/HeJ mice

scientific article published on 01 December 2005

The pathogenesis of alopecia areata in rodent models.

scientific article

The progressive state, in contrast to the stable or regressive state of alopecia areata, is reflected in peripheral blood mononuclear cells.

scientific article

The role of lymphocytes in the development and treatment of alopecia areata

scientific article published on 07 September 2015

Third International Research Workshop on Alopecia Areata

scientific article published on 01 May 1999

Topical FK506: a potent immunotherapy for alopecia areata? Studies using the Dundee experimental bald rat model

scientific article published on 01 October 1997

Transfer of Alopecia Areata to C3H/HeJ Mice Using Cultured Lymph Node-Derived Cells

scientific article published on 06 May 2015

Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)/CD25(-) cells promote systemic alopecia areata and CD4(+)/CD25(+) cells blockade disease onset in the C3H/HeJ mouse model

scientific article published on 01 May 2005

Treatment of alopecia areata in C3H/HeJ mice with the topical immunosuppressant FK506 (Tacrolimus).

scientific article published in September 2001

Treatment of alopecia areata in the DEBR model using Cyclosporin A lipid vesicles.

scientific article published in September 2004

Two sisters, two different hair shaft abnormalities

scientific article published on 26 May 2009

What can we learn from animal models of Alopecia areata?

scientific article

eIF4E is an adverse prognostic marker of melanoma patient survival by increasing melanoma cell invasion

scientific article

List of works by Kevin J McElwee

A "hair-raising" history of alopecia areata

A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma

Abnormal interactions between perifollicular mast cells and CD8+ T-cells may contribute to the pathogenesis of alopecia areata

Allergy promotes alopecia areata in a subset of patients

Allergy to dust mites may contribute to early onset and severity of alopecia areata

Alopecia Areata Susceptibility in Rodent Models ⬇️

Alopecia Areata is Associated with Increased Expression of Heart Disease Biomarker Cardiac Troponin I

Alopecia areata

Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss.

Alopecia areata in humans and other mammalian species.

Alopecia areata update: part II. Treatment

Alopecia areata versus juvenile alopecia in C3H/HeJ mice: tools to dissect the role of inflammation in focal alopecia

Alopecia areata-like hair loss in C3H/HeJ mice and DEBR rats can be reversed using topical diphencyprone

Alopecia areata: pathogenesis and potential for therapy

Animal Models for Alopecia Areata: What and Where?

Apoptosis resistance in peripheral blood lymphocytes of alopecia areata patients.

Assessment of hair density and caliber in Caucasian and Asian female subjects with female pattern hair loss by using the Folliscope.

Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase-I Study

Benefit of different concentrations of intralesional triamcinolone acetonide in alopecia areata: An intrasubject pilot study

Biology of the hair follicle and mechanisms of nonscarring and scarring alopecia.

CXCR3 ligands promote expression of functional indoleamine 2,3-dioxygenase in basal cell carcinoma keratinocytes.

CXCR3/ligands are significantly involved in the tumorigenesis of basal cell carcinomas

Changes in serum free testosterone, sleep patterns, and 5-alpha-reductase type I activity influence changes in sebum excretion in female subjects.

Chronic delayed-type hypersensitivity reaction as a means to treat alopecia areata.

Comparison of alopecia areata in human and nonhuman mammalian species.

Cultured peribulbar dermal sheath cells can induce hair follicle development and contribute to the dermal sheath and dermal papilla

Current and potential agents for the treatment of alopecia areata

Deficiency in nucleotide excision repair family gene activity, especially ERCC3, is associated with non-pigmented hair fiber growth

Development of autoimmune hair loss disease alopecia areata is associated with cardiac dysfunction in C3H/HeJ mice

Diagnosis and management of primary cicatricial alopecia: part II.

Dietary soy oil content and soy-derived phytoestrogen genistein increase resistance to alopecia areata onset in C3H/HeJ mice.

Endogenous retinoids in the pathogenesis of alopecia areata

Etiology of cicatricial alopecias: a basic science point of view.

Etiopathogenesis of alopecia areata: Why do our patients get it?

Examining the relationship between alopecia areata, androgenetic alopecia, and emotional intelligence

Experimental and early investigational drugs for androgenetic alopecia

Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts

Fas-deficient C3.MRL-Tnfrsf6(lpr) mice and Fas ligand-deficient C3H/HeJ-Tnfsf6(gld) mice are relatively resistant to the induction of alopecia areata by grafting of alopecia areata-affected skin from C3H/HeJ mice.

Fibroblast cell-based therapy prevents induction of alopecia areata in an experimental model

Frontal fibrosing alopecia: a retrospective clinical review of 62 patients with treatment outcome and long-term follow-up.

Genetic susceptibility and severity of alopecia areata in human and animal models.

Growth factor concentrations in platelet-rich plasma for androgenetic alopecia: An intra-subject, randomized, blinded, placebo-controlled, pilot study

Hair follicle autoantibodies in DEBR rat sera.

Hair follicle dermal sheath derived cells improve islet allograft survival without systemic immunosuppression.

Hair follicle immune privilege and its collapse in alopecia areata

Hair follicle mesenchyme-associated PD-L1 regulates T-cell activation induced apoptosis: a potential mechanism of immune privilege.

Hair follicles from alopecia areata patients exhibit alterations in immune privilege-associated gene expression in advance of hair loss

High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma

Identification of Autoantigen Epitopes in Alopecia Areata.

Immunotherapy of melanoma: present options and future promises.

In vivo depletion of CD8+ T cells restores hair growth in the DEBR model for alopecia areata

Increased expression of TLR7 and TLR9 in alopecia areata

Increased expression of neuropilin 1 in melanoma progression and its prognostic significance in patients with melanoma.

Integrin β6-deficient mice show enhanced keratinocyte proliferation and retarded hair follicle regression after depilation

Interferon-gamma-deficient mice are resistant to the development of alopecia areata.

Interleukin-10-deficient mice are less susceptible to the induction of alopecia areata

Interleukin-6 cytokine family member oncostatin M is a hair-follicle-expressed factor with hair growth inhibitory properties

Label-free identification and characterization of murine hair follicle stem cells located in thin tissue sections with Raman micro-spectroscopy.

Lichen planopilaris and pseudopelade of Brocq involve distinct disease associated gene expression patterns by microarray

Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis.

Macrophage-stimulating protein promotes hair growth ex vivo and induces anagen from telogen stage hair follicles in vivo.

Major locus on mouse chromosome 17 and minor locus on chromosome 9 are linked with alopecia areata in C3H/HeJ mice

Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata.

Murine cytomegalovirus is not associated with alopecia areata in C3H/HeJ mice

New developments in hair research

Non-scarring patchy alopecia in patients with systemic lupus erythematosus differs from that of alopecia areata

Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis.

Partial restoration of hair growth in the DEBR model for Alopecia areata after in vivo depletion of CD4+ T cells

Prognostic Significance of Nuclear Phospho-ATM Expression in Melanoma

Promising therapies for treating and/or preventing androgenic alopecia

Ratite oils promote keratinocyte cell growth and inhibit leukocyte activation

Reduced Expression of Interleukin-2 Decreases the Frequency of Alopecia Areata Onset in C3H/HeJ Mice

Reduced expression of SRY-box containing gene 17 correlates with an unfavorable melanoma patient survival.

Regulatory T cells in autoimmune diseases and their potential.

Resistance to alopecia areata in C3H/HeJ mice is associated with increased expression of regulatory cytokines and a failure to recruit CD4+ and CD8+ cells.

Sequential cyclic changes of hair roots revealed by dermoscopy demonstrate a progressive mechanism of diffuse alopecia areata over time

Serum level of IL-4 predicts response to topical immunotherapy with diphenylcyclopropenone in alopecia areata

Somatostatin expression in human hair follicles and its potential role in immune privilege

Spontaneous alopecia areata-like hair loss in one congenic and seven inbred laboratory mouse strains