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List of works by Eric J. Nestler

A Conversation with Eric Nestler

scientific article published in January 2014

A Diurnal Rhythm in Pineal Protein 1 Content Mediated by β-Adrenergic Neurotransmission ⬇️

scientific article published on July 23, 1982

A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq

scientific article

A Novel Role of the WNT-Dishevelled-GSK3 Signaling Cascade in the Mouse Nucleus Accumbens in a Social Defeat Model of Depression ⬇️

scientific article published on June 22, 2011

A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress

scientific article

A novel role for E2F3b in regulating cocaine action in the prefrontal cortex

scientific article published on 14 December 2018

A role for repressive histone methylation in cocaine-induced vulnerability to stress

scientific article

A role for ΔFosB in calorie restriction-induced metabolic changes

scientific article

A silent synapse-based mechanism for cocaine-induced locomotor sensitization

scientific article published on June 2011

ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior

scientific article

AMPA antagonist LY293558 blocks the development, without blocking the expression, of behavioral sensitization to morphine

scientific article

Acquisition and maintenance of intravenous cocaine self-administration in Lewis and Fischer inbred rat strains

scientific article published in December 1997

Activator Protein-1: redox switch controlling structure and DNA-binding

scientific article published on 7 September 2017

Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action

scientific article

Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior

scientific article published on 31 July 2008

Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance

scientific article

Advancing drug discovery for schizophrenia

scientific article

Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine

scientific article published on 18 October 2016

Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens

scientific article

An Essential Role for ΔFosB in the Median Preoptic Nucleus in the Sustained Hypertensive Effects of Chronic Intermittent Hypoxia ⬇️

scientific article published on June 11, 2012

An Overview of the Molecular Basis of Epigenetics

An essential role for DeltaFosB in the nucleus accumbens in morphine action

scientific article published on 15 January 2006

Animal models of depression: molecular perspectives

scientific article

Antidepressant action of HDAC inhibition in the prefrontal cortex

scientific article published on 20 April 2015

Antidepressant actions of histone deacetylase inhibitors

scientific article

Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex

scientific article

Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice

scientific article

BAZ1B in Nucleus Accumbens Regulates Reward-Related Behaviors in Response to Distinct Emotional Stimuli

scientific article published on April 2016

BDNF is a negative modulator of morphine action

scientific article

BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors

scientific article published on 14 August 2017

Behavioral and structural responses to chronic cocaine require a feedforward loop involving ΔFosB and calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell

scientific article published on March 2013

Behavioral epigenetics

scientific article

Bioinformatic Analysis for Profiling Drug-induced Chromatin Modification Landscapes in Mouse Brain Using ChlP-seq Data

scientific article

Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature

scientific article published in July 2016

Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons

scientific article published on 06 June 2019

Blockade of melanocortin transmission inhibits cocaine reward

scientific article published on April 2005

Brain region specific actions of regulator of G protein signaling 4 oppose morphine reward and dependence but promote analgesia

scientific article published on 14 November 2009

Brain-Derived Neurotrophic Factor in the Mesolimbic Reward Circuitry Mediates Nociception in Chronic Neuropathic Pain

scientific article published in March 2017

Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors

scientific article

Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability

scientific article published in March 2018

CRACKing the histone code: cocaine's effects on chromatin structure and function

scientific article

CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli

scientific article

CREB modulates excitability of nucleus accumbens neurons

scientific article published on 5 March 2006

CREB modulates the functional output of nucleus accumbens neurons: a critical role of N-methyl-D-aspartate glutamate receptor (NMDAR) receptors

scientific article published on 30 November 2007

CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits

scientific article published on 18 January 2009

Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward

scientific article

Cell-Type-Specific Epigenetic Editing at the Fosb Gene Controls Susceptibility to Social Defeat Stress

scientific article

Cell-Type-Specific Role of ΔFosB in Nucleus Accumbens In Modulating Intermale Aggression

scientific article published on 11 June 2018

Cell-type specific expression of p11 controls cocaine reward

scientific article

Cellular and subcellular localization of protein I in the peripheral nervous system

scientific article

Cellular basis of memory for addiction

scientific article

Characterization of the mouse adenylyl cyclase type VIII gene promoter: regulation by cAMP and CREB.

scientific article published in October 2002

Chromatin regulation in drug addiction and depression

scientific article

Chronic lithium regulates the expression of adenylate cyclase and Gi-protein alpha subunit in rat cerebral cortex

scientific article published on December 1991

Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons

scientific article published on October 1996

Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility

scientific article published on 11 May 2016

Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation

scientific article

Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens

scientific article

Cocaine regulates MEF2 to control synaptic and behavioral plasticity

scientific article

Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2.

scientific article published on 5 May 2017

Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5

scientific journal article

Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster

scientific article published on 12 October 2020

Common molecular and cellular substrates of addiction and memory

scientific article

Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research

scientific article published on July 2016

Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice

scientific article published on 11 March 2020

Correction: PSMC5, a 19S proteasomal ATPase, regulates cocaine action in the nucleus accumbens

scientific article published on 25 June 2015

Corrigendum: Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

scientific article published on 17 June 2015

Critical Role of Histone Turnover in Neuronal Transcription and Plasticity

scientific article published in July 2015

Cyclic Nucleotides in the Nervous System

DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218.

scientific article published on 18 August 2016

Dark Agouti and Fischer 344 rats: differential behavioral responses to morphine and biochemical differences in the ventral tegmental area

scientific article published in January 1999

Decoding the epigenetic language of neuronal plasticity

scientific article published on December 2008

Delta FosB and AP-1-mediated transcription modulate cannabinoid CB₁ receptor signaling and desensitization in striatal and limbic brain regions

scientific article

Delta FosB regulates wheel running.

scientific article published in September 2002

Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet

scientific article published on 26 July 2008

DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses

scientific article

DeltaFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine

scientific article published on 16 December 2008

DeltaFosB: a molecular switch for long-term adaptation in the brain

scientific article

Detection of epigenetic changes using ANOVA with spatially varying coefficients

scientific article published on 13 March 2013

Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats

scientific article

Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress

scientific article

Dimerization and DNA-binding properties of the transcription factor DeltaFosB.

scientific article published on 20 June 2007

Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity

scientific article published in July 2006

Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies

scientific article published on 28 January 2008

Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors

scientific article

Distinctive roles for amygdalar CREB in reconsolidation and extinction of fear memory

scientific article published on 13 April 2012

Distribution of protein I in mammalian brain as determined by a detergent-based radioimmunoassay

scientific article

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

scientific article

Dopamine and depolarizing agents regulate the state of phosphorylation of protein I in the mammalian superior cervical sympathetic ganglion ⬇️

scientific article published on December 1, 1980

Dopaminergic dynamics underlying sex-specific cocaine reward

scientific article published on 10 January 2017

Downregulation of the CCAAT-Enhancer Binding Protein β in ΔFosB Transgenic Mice and by Electroconvulsive Seizures ⬇️

scientific article published on January 1, 2004

Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need

scientific article published on 18 April 2024

Early life programming and neurodevelopmental disorders

scientific article

Early life stress alters transcriptomic patterning across reward circuitry in male and female mice

scientific article published on 08 November 2019

Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2.

scientific article published in June 2017

Early stress evokes age-dependent biphasic changes in hippocampal neurogenesis, BDNF expression, and cognition

scientific article

Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens ⬇️

scientific article published on September 3, 2011

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

scientific article

Effects of drugs of abuse on the brain during development. Foreword

scientific article published on 17 April 2009

Effects of gaboxadol on the expression of cocaine sensitization in rats

scientific article published on 22 February 2016

Effects of striatal ΔFosB overexpression and ketamine on social defeat stress-induced anhedonia in mice

scientific article

Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder

scholarly article by Aaron Tan et al published 1 November 2018 in Molecular Psychiatry

Elevated levels of GluR1 in the midbrain: a trigger for sensitization to drugs of abuse?

scientific article

Energy expenditure and bone formation share a common sensitivity to AP-1 transcription in the hypothalamus

scientific article

Environmental Programming of Susceptibility and Resilience to Stress in Adulthood in Male Mice

Epigenetic Basis of Mental Illness

scientific article published on 08 October 2015

Epigenetic Mechanisms in Psychiatry ⬇️

scientific article published on January 1, 2013

Epigenetic Mechanisms of Depression and Antidepressant Action ⬇️

scientific article published on September 27, 2012

Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area

scientific article

Epigenetic mechanisms in drug addiction

scientific article

Epigenetic mechanisms in psychiatry

scientific article published in February 2009

Epigenetic mechanisms of chronic pain

scientific article

Epigenetic mechanisms of depression

scientific article

Epigenetic mechanisms of drug addiction

scientific article

Epigenetic mechanisms of drug addiction

scientific article published on 29 January 2013

Epigenetic signaling in psychiatric disorders.

scientific article

Epigenetic signaling in psychiatric disorders: stress and depression.

scientific article

Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits

scientific article

Epigenetics

scholarly article

Epigenetics of Psychiatric Diseases

Epigenetics of the depressed brain: role of histone acetylation and methylation

scientific article

Epigenetics: Stress makes its molecular mark

scientific article published on October 2012

Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress-Induced Depressive Behaviors

scientific article published on 15 December 2015

Essential role for RGS9 in opiate action ⬇️

scientific article published on October 31, 2003

Essential role of brain-derived neurotrophic factor in adult hippocampal function

scientific article

Essential role of poly(ADP-ribosyl)ation in cocaine action

scientific journal article

Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons

scientific article

Essential role of the histone methyltransferase G9a in cocaine-induced plasticity

scientific article

Establishment of a repeated social defeat stress model in female mice

scientific article published on 9 October 2017

Extracellular signal-regulated kinase-2 within the ventral tegmental area regulates responses to stress

scientific article

FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics

scientific article

Fluoxetine epigenetically alters the CaMKIIα promoter in nucleus accumbens to regulate ΔFosB binding and antidepressant effects

scientific article

Fluoxetine exposure during adolescence alters responses to aversive stimuli in adulthood

scientific article published on January 2014

Fos B mutant mice: Loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine’s psychomotor and rewarding effects ⬇️

scientific article published on September 16, 1997

FosB Is Essential for the Enhancement of Stress Tolerance and Antagonizes Locomotor Sensitization by ΔFosB ⬇️

scientific article published on June 15, 2011

From Father to Offspring: Paternal Transmission of Depressive-Like Behaviors ⬇️

scientific article published on January 1, 2012

From neurobiology to treatment: progress against addiction

scientific article

From synapse to nucleus: novel targets for treating depression

scientific article

Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: viral transfections, subacute and chronic treatments with 5-HT4 agonists

scientific article published in April 2005

Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission

journal article published in 2015

Functional role of the N-terminal domain of ΔFosB in response to stress and drugs of abuse

scientific article

G9a influences neuronal subtype specification in striatum

scientific journal article

Gadd45b mediates depressive-like role through DNA demethylation

article published in 2019

Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder

scientific article

Genetic analysis of behavioral, neuroendocrine, and biochemical parameters in inbred rodents: initial studies in Lewis and Fischer 344 rats and in A/J and C57BL/6J mice

scientific article published in September 1998

Genome-wide transcriptional profiling of central amygdala and orbitofrontal cortex during incubation of methamphetamine craving

scientific article published on 20 July 2018

Genomic regions controlling corticosterone levels in rats

scientific article published in March 2004

Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine

scientific article published on 16 January 2018

Hcrtr1 and 2 signaling differentially regulates depression-like behaviors ⬇️

scientific article published on March 4, 2011

Hidden Switches in the Mind ⬇️

scientific article published on December 1, 2011

Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition ⬇️

scientific article published on February 16, 2011

Histone acetylation in drug addiction

scientific article published on 22 January 2009

Histone arginine methylation in cocaine action in the nucleus accumbens

scientific article published on 09 August 2016

Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures.

scientific article

Historical review: Molecular and cellular mechanisms of opiate and cocaine addiction

scientific article published on April 2004

Homeostatic and hedonic signals interact in the regulation of food intake

scientific article published on 28 January 2009

Human Transcriptome and Chromatin Modifications: An ENCODE Perspective

scientific article (publication date: June 2013)

Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models

scientific article published on June 2009

Impaired adult myelination in the prefrontal cortex of socially isolated mice

scientific article

In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens

scientific article published on 07 June 2017

In need of high-throughput behavioral systems

scientific article

In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward

scientific article

In vivo locus-specific editing of the neuroepigenome

scientific article published on 23 July 2020

Increased cyclic GMP levels associated with contraction in muscle fibres of the giant barnacle ⬇️

scientific article published on June 9, 1977

Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex

scientific article published on 06 June 2008

Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor

scientific article published on May 1998

Inducible and brain region-specific CREB transgenic mice

scientific article published in June 2002

Inducible, reversible hair loss in transgenic mice

scientific article

Induction in Nucleus Accumbens by Cocaine Is Regulated by E2F3a

scientific article published on 01 March 2019

Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses

scientific article

Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine

scholarly article

Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect.

scientific article

Integration of evidence across human and model organism studies: A meeting report

scientific article published on 24 April 2021

Involvement of the Lateral Hypothalamic Peptide Orexin in Morphine Dependence and Withdrawal ⬇️

scientific article published on April 15, 2003

Is there a common molecular pathway for addiction?

scientific article

It is time to take a stand for medical research and against terrorism targeting medical scientists

scientific article

Kappa opioid receptor signaling in the basolateral amygdala regulates conditioned fear and anxiety in rats

scientific article

Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles

scientific article published on 18 June 2016

Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety

scientific article published on 26 December 2018

Lateral hypothalamic neuropeptides in reward and drug addiction

scientific article

Linking Molecules to Mood: New Insight Into the Biology of Depression ⬇️

scientific article published on September 15, 2010

Long-Term Behavioral Effects of Post-weaning Social Isolation in Males and Females

Long-term haloperidol administration enhances and short-term administration attenuates the behavioral effects of cocaine in a place conditioning procedure

scientific article

Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition

scientific article

Maintaining a Steady Course

Mania-like behavior induced by disruption of CLOCK

scientific article

Mapping Brain Metabolic Connectivity in Awake Rats with μPET and Optogenetic Stimulation ⬇️

scientific article published on April 10, 2013

Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving

scientific article

MeCP2 and drug addiction ⬇️

scientific article published on September 1, 2010

Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action

scientific article

Methylation in OTX2 and related genes, maltreatment, and depression in children

scientific article published on 21 July 2018

Methylphenidate treatment during pre- and periadolescence alters behavioral responses to emotional stimuli at adulthood

scientific article published in December 2003

MiR-218: a molecular switch and potential biomarker of susceptibility to stress

scientific article published on 12 April 2019

Molecular mechanisms of drug addiction

scientific article published on 01 January 2004

Molecular neurobiology of drug addiction

scientific article

Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons.

scientific article

Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area

scientific article

Morphine epigenomically regulates behavior through alterations in histone H3 lysine 9 dimethylation in the nucleus accumbens

scientific article published on November 2012

Multiple actions of spinophilin regulate mu opioid receptor function

scientific journal article

NEURAL MECHANISMS OF ADDICTION: The Role of Reward-Related Learning and Memory

scientific article

Nerve impulses increase the phosphorylation state of protein I in rabbit superior cervical ganglion ⬇️

scientific article published on April 1, 1982

Nerve injury-induced epigenetic silencing of opioid receptors controlled by DNMT3a in primary afferent neurons

scientific article

Neural Substrates of Depression and Resilience

scientific article published on 10 April 2017

Neuroanatomic Differences Associated With Stress Susceptibility and Resilience

scientific article published on 18 August 2015

Neurobehavioral assessment in the information age.

scientific article published on May 2004

Neurobiological Sequelae of Witnessing Stressful Events in Adult Mice ⬇️

scientific article published on July 12, 2012

Neurobiology of resilience

scientific article

Neurodegenerative dementias: connecting psychiatry and neurology through a shared neurobiology

scientific article

Neuroepigenetic Editing

scientific article published in January 2018

Neuroepigenetics and addiction

scientific article published in January 2018

Neuron-specific phosphoproteins in mammalian brain

scientific article published on January 1, 1984

Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice

scientific article

Neuronal phosphoproteins: physiological and clinical implications

scientific article published on September 1984

Neuroplasticity mediated by altered gene expression

scientific article published on 29 August 2007

Neurotrophic factors and structural plasticity in addiction

scientific article published on 04 July 2008

Neurotrophic mechanisms in drug addiction

scientific article published on January 2004

Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawal

scientific article published in September 2001

New approaches to antidepressant drug discovery: beyond monoamines

scientific article

Nicotinic cholinergic stimulation increases cyclic GMP levels in vertebrate skeletal muscle ⬇️

scientific article published on October 5, 1978

Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling

scientific article

Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior

scientific article

Nucleus accumbens feedforward inhibition circuit promotes cocaine self-administration

scientific article published on 25 September 2017

Obituary: Patricia S. Goldman-Rakic (1937-2003).

scientific article

Opiate-Induced Molecular and Cellular Plasticity of Ventral Tegmental Area and Locus Coeruleus Catecholamine Neurons ⬇️

scientific article published on July 1, 2012

Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice

scientific article published on 13 April 2020

Overexpression of CREB in the Nucleus Accumbens Shell Increases Cocaine Reinforcement in Self-Administering Rats ⬇️

scientific article published on November 9, 2011

Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment

scientific article

Overexpression of the histone dimethyltransferase G9a in nucleus accumbens shell increases cocaine self-administration, stress-induced reinstatement, and anxiety.

scientific article published on 7 December 2017

P.1.05 Involvement of DARPP-32, FosB, and dynorphin in voluntary wheel running

PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens

scientific article published on 11 May 2015

Pamela Sklar (1959–2017)

Pathological gambling: focusing on the addiction, not the activity

scientific article published in February 2006

Personal reflections on a mentor extraordinaire: Paul Greengard, Ph.D. (1925-2019)

scientific article published on 13 June 2019

Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice

scientific article

Phospholipase C gamma in distinct regions of the ventral tegmental area differentially regulates morphine-induced locomotor activity

scientific article

Phospholipase Cgamma in distinct regions of the ventral tegmental area differentially modulates mood-related behaviors.

scientific article published in August 2003

Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action

scientific article

Phylogenetic survey of proteins related to synapsin I and biochemical analysis of four such proteins from fish brain

scientific article published in July 1985

Planning the New National Institute on Substance Use and Addiction Disorders ⬇️

scientific article published on June 8, 2012

Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b.

scientific article published on July 2017

Potential Utility of Optogenetics in the Study of Depression ⬇️

scientific article published on 08 February 2012

Preclinical models: status of basic research in depression

scientific article

Preface

Principles of Signal Transduction

Proenkephalin Mediates the Enduring Effects of Adolescent Cannabis Exposure Associated with Adult Opiate Vulnerability ⬇️

scientific article published on June 8, 2012

Proteasome-dependent and -independent mechanisms for FosB destabilization: identification of FosB degron domains and implications for DeltaFosB stability

scientific article

Protein phosphorylation in the brain

scientific article published on October 1983

Psychobiology and molecular genetics of resilience

scientific article

Quantitative trait locus analysis identifies rat genomic regions related to amphetamine-induced locomotion and Galpha(i3) levels in nucleus accumbens

scientific article

RGS9 modulates dopamine signaling in the basal ganglia

scientific article published on June 2003

Rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons

scientific article published on June 2012

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

scientific article

Re-silencing of silent synapses unmasks anti-relapse effects of environmental enrichment

scientific article published on 18 April 2016

Reflections on: "A general role for adaptations in G-Proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function".

scientific article

Regional and cellular mapping of cAMP response element-mediated transcription during naltrexone-precipitated morphine withdrawal.

scientific article published in May 2002

Regulation of BAZ1A and nucleosome positioning in the nucleus accumbens in response to cocaine

scientific article published on 12 April 2017

Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo

scientific article

Regulation of CRE-mediated transcription in mouse brain by amphetamine

scientific article

Regulation of DeltaFosB stability by phosphorylation.

scientific article

Regulation of DeltaFosB transcriptional activity by Ser27 phosphorylation

scientific article

Regulation of RGS proteins by chronic morphine in rat locus coeruleus

scientific article published in March 2003

Regulation of anxiety and initiation of sexual behavior by CREB in the nucleus accumbens

scientific article

Regulation of chromatin states by drugs of abuse

scientific article

Regulation of cocaine reward by CREB.

scientific article

Regulation of dopaminergic transmission and cocaine reward by the Clock gene

scientific article

Regulation of fosB and DeltafosB mRNA expression: in vivo and in vitro studies

scientific article published on 27 January 2007

Regulation of gene expression and cocaine reward by CREB and ΔFosB ⬇️

scientific article published on October 19, 2003

Regulation of gene expression by chronic morphine and morphine withdrawal in the locus ceruleus and ventral tegmental area.

scientific article

Regulation of impulsive and aggressive behaviours by a novel lncRNA

scientific article published on 06 January 2020

Regulation of morphine reward and feeding by CREB in the lateral hypothalamus

scientific article published in February 2007

Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein.

scientific article published in May 2002

Regulation of neuronal PLCgamma by chronic morphine

scientific journal article

Regulation of regulators of G protein signaling mRNA expression in rat brain by acute and chronic electroconvulsive seizures

scientific article published in August 2002

Reinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine

scientific article

Repressive Epigenetic Changes at the mGlu2 Promoter in Frontal Cortex of 5-HT2A Knockout Mice ⬇️

scientific article published on March 18, 2013

Review. Transcriptional mechanisms of addiction: role of DeltaFosB

scientific article

Role of Tet1 and 5-hydroxymethylcytosine in cocaine action

scientific article

Role of cAMP response element-binding protein in the rat locus ceruleus: regulation of neuronal activity and opiate withdrawal behaviors.

scientific article published in April 2006

Role of the Brain's Reward Circuitry in Depression: Transcriptional Mechanisms

scientific article

Ronald S. Duman, Ph.D. (1954-2020)

scientific article published on 19 February 2020

SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens.

scientific article published on August 2016

Self-administration of ethanol, cocaine, or nicotine does not decrease the soma size of ventral tegmental area dopamine neurons

scientific article (publication date: 2014)

Sensitization to Morphine Induced by Viral-Mediated Gene Transfer ⬇️

scientific article published on August 8, 1997

Serum response factor and cAMP response element binding protein are both required for cocaine induction of ΔFosB.

scientific article

Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress.

scientific article

Sex-specific transcriptional signatures in human depression

scientific article published on 21 August 2017

Silent synapses dictate cocaine memory destabilization and reconsolidation

scientific article published on 02 December 2019

Small molecule screening identifies regulators of the transcription factor ΔFosB

scientific article published on 29 March 2012

Stereotaxic Surgery and Viral Delivery of Zinc-Finger Epigenetic Editing Tools in Rodent Brain

scientific article published on 01 January 2018

Stimulation of protein kinase a activity in the rat amygdala enhances reward-related learning

scientific article

Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway

scientific article published on 24 November 2013

Stress and Cocaine Trigger Divergent and Cell Type-Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens

scientific article published on 6 June 2015

Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex

scientific article published on 19 August 2019

Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine

scientific article

Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease

scientific article

Striatal regulation of ΔFosB, FosB, and cFos during cocaine self-administration and withdrawal

scientific article

Subregional, Dendritic Compartment, and Spine Subtype Specificity in Cocaine Regulation of Dendritic Spines in the Nucleus Accumbens ⬇️

scientific article published on May 16, 2012

Susceptibility to chronic social stress increases plaque progression, vulnerability and platelet activation.

scientific article

Synapsin I: a review of its distribution and biological regulation

scientific article published on January 1986

Synaptic Microtubule-Associated Protein EB3 and SRC Phosphorylation Mediate Structural and Behavioral Adaptations During Withdrawal From Cocaine Self-Administration

scientific article published on 15 May 2019

Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior

scientific article

Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

scientific article published on 11 January 2017

The Striatal Balancing Act in Drug Addiction: Distinct Roles of Direct and Indirect Pathway Medium Spiny Neurons ⬇️

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