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List of works by Nikos S Hatzakis

A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories

scientific article published in 2022

A large size-selective DNA nanopore with sensing applications

scientific article published on 11 December 2019

A unifying mechanism accounts for sensing of membrane curvature by BAR domains, amphipathic helices and membrane-anchored proteins.

scientific article published on 16 December 2009

Asymmetric transesterification of secondary alcohols catalyzed by feruloyl esterase from Humicola insolens

scientific article published in August 2005

Beta-cyclodextrin-appended giant amphiphile: aggregation to vesicle polymersomes and immobilisation of enzymes

scientific article

Bionanoconjugation via Click Chemistry: The Creation of Functional Hybrids of Lipases and Gold Nanoparticles

scientific article published on 01 November 2006

Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum.

scientific article

Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity

scientific article published on 29 November 2018

Deep learning assisted single particle tracking for automated correlation between diffusion and function

DeepFRET, a software for rapid and automated single-molecule FRET data classification using deep learning

scientific article published on 03 November 2020

Direct Observation of Sophorolipid Micelle Docking in Model Membranes and Cells by Single Particle Studies Reveals Optimal Fusion Conditions

scientific article published on 07 September 2020

Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition

scientific article published on 07 November 2019

Direct observation of multiple conformational states in Cytochrome P450 oxidoreductase and their modulation by membrane environment and ionic strength

scientific article published in Scientific Reports

Direct observation of proton pumping by a eukaryotic P-type ATPase.

scientific article published on March 2016

Do enzymes sleep and work?

scientific article

Effects of membrane curvature and pH on proton pumping activity of single cytochrome bo3 enzymes ⬇️

scientific article published on 17 June 2017

Half-Life Extending Modifications of Peptide YY3-36 Direct Receptor-Mediated Internalization

scientific article published on 25 July 2019

How curved membranes recruit amphipathic helices and protein anchoring motifs

scientific article published on 13 September 2009

Influence of lipid heterogeneity and phase behavior on phospholipase A2 action at the single molecule level

scientific article published on May 2010

Influence of the preparation route on the supramolecular organization of lipids in a vesicular system.

scientific article

Membrane Curvature and Lipid Composition Synergize To Regulate N-Ras Anchor Recruitment

scientific article

Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases

scientific article published on 26 January 2015

Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells.

scientific article published on 8 May 2017

Mixing subattolitre volumes in a quantitative and highly parallel manner with soft matter nanofluidics

scientific article published on 30 October 2011

Monitoring shifts in the conformation equilibrium of the membrane protein cytochrome P450 reductase (POR) in nanodiscs

scientific article

Observation of Inhomogeneity in the Lipid Composition of Individual Nanoscale Liposomes ⬇️

scientific article published on June 28, 2011

Optically induced linking of protein and nanoparticles to gold surfaces.

scientific article published in June 2010

Oxidation of benzyl alcohols by dimethyldioxirane. The question of concerted versus stepwise mechanisms probed by kinetic isotope effects

article published in 2001

Positional Assembly of Enzymes in Polymersome Nanoreactors for Cascade Reactions

scientific article published on 01 January 2007

Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3 + 2] dipolar cycloaddition reaction

scientific article

Quantification of Functional Dynamics of Membrane Proteins Reconstituted in Nanodiscs Membranes by Single Turnover Functional Readout.

scientific article published on 18 October 2016

Shedding light on protein folding, structural and functional dynamics by single molecule studies

scientific article

Single Enzyme Experiments Reveal a Long-Lifetime Proton Leak State in a Heme-Copper Oxidase ⬇️

scientific article

Single Liposome Measurements for the Study of Proton-Pumping Membrane Enzymes Using Electrochemistry and Fluorescent Microscopy

scientific article published on 21 February 2019

Single enzyme studies reveal the existence of discrete functional states for monomeric enzymes and how they are "selected" upon allosteric regulation.

scientific article published on 21 May 2012

Single molecule activity measurements of cytochrome P450 oxidoreductase reveal the existence of two discrete functional states

scientific article

Single molecule insights on conformational selection and induced fit mechanism

scientific article

Synthesis and single enzyme activity of a clicked lipase–BSA hetero-dimer

scientific article published on 09 February 2006

The enzyme mechanism of nitrite reductase studied at single-molecule level

scholarly article

Ultrasmall TPGS-PLGA Hybrid Nanoparticles for Site-Specific Delivery of Antibiotics into Pseudomonas aeruginosa Biofilms in Lungs

scientific article published on 17 December 2019

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