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List of works by Ikuo Hirono

A Hint of Primitive Mucosal Immunity in Shrimp through Marsupenaeus japonicus Gill C-Type Lectin

scientific article published on 13 September 2019

A cDNA microarray approach for analyzing transcriptional changes in Penaeus monodon after infection by pathogens ⬇️

scientific article published on October 29, 2010

A novel immune-related gene, microtubule aggregate protein homologue, is up-regulated during IFN-γ-related immune responses in Japanese flounder, Paralichthys olivaceus.

scientific article published on 30 July 2011

A novel viral responsive protein (MjVRP) from Marsupenaeus japonicus haemocytes is involved in white spot syndrome virus infection.

scientific article published on 18 September 2017

A novel white spot syndrome virus protein WSSV164 controls prophenoloxidases, PmproPOs in shrimp melanization cascade

scientific article published on 04 May 2018

A novel white spot syndrome virus-induced gene (MjVIG1) from Marsupenaeus japonicus hemocytes.

scientific article published on 19 March 2018

A peroxiredoxin from kuruma shrimp, Marsupenaeus japonicus, inhibited by peptidoglycan.

scientific article published on 13 August 2007

A rapid method for simultaneously diagnosing four shrimp diseases using PCR-DNA chromatography method.

scientific article published on 24 October 2017

A soluble nonglycosylated recombinant infectious hematopoietic necrosis virus (IHNV) G-protein induces IFNs in rainbow trout (Oncorhynchus mykiss).

scientific article

A transferable 20-kilobase multiple drug resistance-conferring R plasmid (pKL0018) from a fish pathogen (Lactococcus garvieae) is highly homologous to a conjugative multiple drug resistance-conferring enterococcal plasmid.

scientific article published on 13 February 2009

Activation of PmRelish from Penaeus monodon by yellow head virus.

scientific article published on 21 November 2014

Adjuvant effects on protection and immune response of Japanese flounder immunized by the formalin-killed cells of Edwardsiella tarda

scientific article published on 27 September 2018

Anti-PirA-like toxin immunoglobulin (IgY) in feeds passively immunizes shrimp against acute hepatopancreatic necrosis disease

scientific article published on 21 May 2019

Anti-lipopolysaccharide factor isoform 3 from Penaeus monodon (ALFPm3) exhibits antiviral activity by interacting with WSSV structural proteins.

scientific article

BCG vaccine confers adaptive immunity against Mycobacterium sp. infection in fish

scientific article published on 11 September 2009

Bacterial classification of fish-pathogenic Mycobacterium species by multigene phylogenetic analyses and MALDI Biotyper identification system.

scientific article

Biological characterisation of a recombinant Atlantic salmon type I interferon synthesized in Escherichia coli.

scientific article published on 25 October 2007

CD4 and CD8 homologues in Japanese flounder, Paralichthys olivaceus: Differences in the expressions and localizations of CD4-1, CD4-2, CD8α and CD8β.

scientific article published on 23 October 2012

Characterization and antiviral function of a cytosolic sensor gene, MDA5, in Japanese flounder, Paralichthys olivaceus

scientific article published on 24 December 2010

Characterization and gene expression of transcription factors, PU.1 and C/EBPα driving transcription from the tumor necrosis factor α promoter in Japanese flounder, Paralichthys olivaceus

scientific article

Characterization of a Kunitz-type protease inhibitor (MjKuPI) reveals the involvement of MjKuPI positive hemocytes in the immune responses of kuruma shrimp Marsupenaeus japonicus.

scientific article published on 30 May 2016

Characterization of crustin antimicrobial proteins from Japanese spiny lobster Panulirus japonicus

scientific article

Characterization of polyclonal antibodies against Japanese flounder IgM derived from recombinant IgM constant region proteins.

scientific article published on 28 March 2009

Characterization of two isoforms of Japanese spiny lobster Panulirus japonicus defensin cDNA.

scientific article

Class B CpG-ODN2006 is highly associated with IgM and antimicrobial peptide gene expression through TLR9 pathway in yellowtail Seriola lalandi.

scientific article

Cloning and characterization of the IkappaBalpha gene from Japanese flounder, Paralichthys olivaceus.

scientific article published on 14 March 2007

Cloning and expression analysis of three novel CC chemokine genes from Japanese flounder (Paralichthys olivaceus).

scientific article published on 12 August 2014

Comparative analysis and distribution of pP9014, a novel drug resistance IncP-1 plasmid from Photobacterium damselae subsp. piscicida.

scientific article published on 18 April 2013

Comparative analysis of two types of CXCL8 from Japanese flounder (Paralichthys olivaceus).

scientific article published on 23 April 2015

Comparative genome analysis of fish and human isolates of Mycobacterium marinum.

scientific article

Comparative genome analysis of fish pathogen Flavobacterium columnare reveals extensive sequence diversity within the species.

scientific article

Comparative genomic characterization of three Streptococcus parauberis strains in fish pathogen, as assessed by wide-genome analyses

scientific article (publication date: 2013)

Comparative genomics inferred two distinct populations of piscine pathogenic Streptococcus agalactiae, serotype Ia ST7 and serotype III ST283, in Thailand and Vietnam

scientific article published on 17 November 2018

Comparative sequence analysis of a multidrug-resistant plasmid from Aeromonas hydrophila.

scientific article published on 15 October 2012

Comparative sequence analysis of crustin isoform MjCRS7 and MjWFDC-like gene from kuruma shrimp Marsupenaeus japonicus shows variant of the WFDC domain

article

Complete Genome Sequence of Ichthyobacterium seriolicida JBKA-6T, Isolated from Yellowtail (Seriola quinqueradiata) Affected by Bacterial Hemolytic Jaundice.

scientific article published on 9 February 2017

Complete Genome Sequence of the Lytic Giant Bacteriophage pT24 Infecting Tenacibaculum spp., Isolated from a Shrimp Culture Pond

scientific article published on 6 July 2017

Complete genome sequence and immunoproteomic analyses of the bacterial fish pathogen Streptococcus parauberis

scientific article

Comprehensive gene expression profiling in Japanese flounder kidney after injection with two different formalin-killed pathogenic bacteria

scientific article published on 07 October 2014

Crustacean Genome Exploration Reveals the Evolutionary Origin of White Spot Syndrome Virus

scientific article published on 17 January 2019

Cytotoxicity of Streptococcus agalactiae secretory protein on tilapia cultured cells

scientific article published on 10 August 2020

DNA microarray analysis on gene candidates possibly related to tetrodotoxin accumulation in pufferfish.

scientific article published on 7 November 2013

Deep sequencing of ESTs from nacreous and prismatic layer producing tissues and a screen for novel shell formation-related genes in the pearl oyster

scientific article (publication date: 2011)

Detection of acute hepatopancreatic necrosis disease strain of Vibrio parahaemolyticus using loop-mediated isothermal amplification.

scientific article published on 19 May 2015

Development and evaluation of polyclonal antisera for detection of the IgM heavy chain of multiple fish species.

scientific article published on 23 June 2017

Differences in lipid distribution and expression of peroxisome proliferator-activated receptor gamma and lipoprotein lipase genes in torafugu and red seabream.

scientific article published on 19 January 2013

Differential gene expression in black tiger shrimp, Penaeus monodon, following administration of oxytetracycline and oxolinic acid.

scientific article published on 12 June 2009

Differential gene expression profiles in Japanese flounder (Paralichthys olivaceus) with different susceptibilities to edwardsiellosis

scientific article published on 14 July 2010

Disinfection of an EMS/AHPND strain of Vibrio parahaemolyticus using ozone nanobubbles

scientific article

Diversity of Lipid Distribution in Fish Skeletal Muscle.

scientific article published in April 2016

Draft Genome Sequence of Non-Vibrio parahaemolyticus Acute Hepatopancreatic Necrosis Disease Strain KC13.17.5, Isolated from Diseased Shrimp in Vietnam

scientific article

Draft Genome Sequence of Vibrio penaeicida Strain TUMSAT-NU1, Isolated from Diseased Shrimp in Japan.

scientific article published on 15 March 2018

Draft Genome Sequences of Six Strains of Vibrio parahaemolyticus Isolated from Early Mortality Syndrome/Acute Hepatopancreatic Necrosis Disease Shrimp in Thailand

scientific article

Draft Genome Sequences of Streptococcus agalactiae Serotype Ia and III Isolates from Tilapia Farms in Thailand.

scientific article

Draft Genome Sequences of Streptococcus agalactiae Strains Isolated from Nile Tilapia (Oreochromis niloticus) Farms in Thailand.

scientific article

Draft Genome Sequences of Vibrio atypicus Strains DSM 25292T and TUMSAT1

scientific article published on 06 February 2020

Drug resistance mechanism of the fish-pathogenic bacterium Lactococcus garvieae.

scientific article published in June 2008

EST analysis on adipose tissue of rainbow trout Oncorhynchus mykiss and tissue distribution of adiponectin

scientific article published on 25 June 2011

Edible mushroom (Flammulina velutipes) extract inhibits melanosis in Kuruma shrimp (Marsupenaeus japonicus)

scientific article published on 10 November 2010

Effects of 5-Aminolevulinic Acid on Gene Expression, Immunity, and ATP Levels in Pacific White Shrimp, Litopenaeus vannamei

scientific article published on 25 August 2018

Effects of ergothioneine from mushrooms (Flammulina velutipes) on melanosis and lipid oxidation of kuruma shrimp (Marsupenaeus japonicus).

scientific article published in February 2010

Engineered virus-encoded pre-microRNA (pre-miRNA) induces sequence-specific antiviral response in addition to nonspecific immunity in a fish cell line: convergence of RNAi-related pathways and IFN-related pathways in antiviral response.

scientific article

Enhanced survival of shrimp, Penaeus (Marsupenaeus) japonicus from white spot syndrome disease after oral administration of recombinant VP28 expressed in Brevibacillus brevis.

scientific article published on 2 May 2008

Essential function of transglutaminase and clotting protein in shrimp immunity

scientific article published on 30 October 2007

Evaluation of ToxA and Vibrio parahaemolyticus lysate on humoral immune response and immune-related genes in Pacific red snapper.

scientific article published on 11 July 2016

Evolutional conservation of molecular structure and antiviral function of a viral RNA receptor, LGP2, in Japanese flounder, Paralichthys olivaceus.

scientific article published on 22 November 2010

Extracellular trap formation in kuruma shrimp (Marsupenaeus japonicus) hemocytes is coupled with c-type lysozyme.

scientific article

Fosmid library end sequencing reveals a rarely known genome structure of marine shrimp Penaeus monodon

scientific article

Functional analysis of C-type lysozyme in penaeid shrimp.

scientific article published on 8 November 2011

Gene Expression Profile of Hemocytes of Kuruma Shrimp, Marsupenaeus japonicus Following Peptidoglycan Stimulation

article

Gene expression analysis of common carp (Cyprinus carpio L.) lines during Cyprinid herpesvirus 3 infection yields insights into differential immune responses.

scientific article published on 24 December 2011

Gene silencing of VP9 gene impairs WSSV infectivity on Macrobrachium rosenbergii.

scientific article published on 23 January 2016

Gene silencing of a prophenoloxidase activating enzyme in the shrimp, Penaeus monodon, increases susceptibility to Vibrio harveyi infection.

scientific article published on 12 February 2009

Genome characterization of piscine 'Scale drop and Muscle Necrosis syndrome'-associated strain of Vibrio harveyi focusing on bacterial virulence determinants

scientific article published on 27 December 2017

Genomic comparison between pathogenic Streptococcus agalactiae isolated from Nile tilapia in Thailand and fish-derived ST7 strains.

scientific article published on 8 October 2015

Gills specific type 2 crustin isoforms: Its molecular cloning and characterization from kuruma shrimp Marsupenaeus japonicus.

scientific article published on 26 March 2018

Growth differentiation factor 15, a novel acute phase response gene in Japanese flounder, Paralichthys olivaceus.

scientific article

Hematopoietic tissue of Macrobrachium rosenbergii plays dual roles as a source of hemocyte hematopoiesis and as a defensive mechanism against Macrobrachium rosenbergii nodavirus infection

scientific article published on 13 December 2018

Homology modeling and virtual screening for antagonists of protease from yellow head virus.

scientific article published on 22 February 2014

Hyper-expansion of large DNA segments in the genome of kuruma shrimp, Marsupenaeus japonicus

scientific article

Ichthyobacterium seriolicida gen. nov., sp. nov., a member of the phylum 'Bacteroidetes', isolated from yellowtail fish (Seriola quinqueradiata) affected by bacterial haemolytic jaundice, and proposal of a new family, Ichthyobacteriaceae fam. nov.

scientific article

Identification and characterization of Japanese flounder, Paralichthys olivaceus interferon-stimulated gene 15 (Jf-ISG15).

scientific article

Identification and expression analysis of Fc receptor-like proteins in Japanese flounder (Paralichthys olivaceus)

scientific article published on 04 January 2019

Identification and expression analysis of suppressors of cytokine signaling (SOCS) of Japanese flounder Paralichthys olivaceus.

scientific article published on 14 September 2016

Identification of 2 novel type I IFN genes in Japanese flounder, Paralichthys olivaceus

scientific article published on 22 May 2017

Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus.

scientific article published on 18 May 2007

Identification of an anti-lipopolysaccharide factor AV-R isoform (LvALF AV-R) related to Vp_PirAB-like toxin resistance in Litopenaeus vannamei

scientific article published on 04 October 2018

Identification of endonuclease domain-containing 1 gene in Japanese flounder Paralichthys olivaceus

scientific article

Identification of novel copper/zinc superoxide dismutase (Cu/ZnSOD) genes in kuruma shrimp Marsupenaeus japonicus

scientific article published on 8 August 2014

Identification of novel genes in Japanese flounder (Paralichthys olivaceus) head kidney up-regulated after vaccination with Streptococcus iniae formalin-killed cells

scientific article published on 01 April 2008

Identification of novel interleukin 1 beta family genes in Japanese flounder Paralichthys olivaceus.

scientific article published on 13 October 2012

Identification of two distinct types of beta-2 microglobulin in marine fish, Pagrus major and Seriola quinqueradiata.

scientific article published on 23 September 2009

Identification, characterization, and expression of the genes TektinA1 and Axonemal protein 66.0 in the tropical abalone Haliotis asinina.

scientific article published on June 2009

Immune-related gene expression profiling of yellowtail (Seriola quinqueradiata) kidney cells stimulated with ConA and LPS using microarray analysis.

scientific article published on 5 October 2007

In vivo and in vitro studies using larval and adult antigens from Neobenedenia melleni on immune response in yellowtail (Seriola lalandi).

scientific article published on 19 April 2017

Increasing of temperature induces pathogenicity of Streptococcus agalactiae and the up-regulation of inflammatory related genes in infected Nile tilapia (Oreochromis niloticus).

scientific article published on 30 April 2014

Influence of temperature on Mx gene expression profiles and the protection of sevenband grouper, Epinephelus septemfasciatus, against red-spotted grouper nervous necrosis virus (RGNNV) infection after poly (I:C) injection.

scientific article published on 7 August 2014

Inhibition of Hirame rhabdovirus growth by RNA aptamers.

scientific article published on 3 September 2012

Innate immunomodulation with recombinant interferon-alpha enhances resistance of rainbow trout (Oncorhynchus mykiss) to infectious hematopoietic necrosis virus.

scientific article published on 8 May 2008

Interaction between type I interferon and Cyprinid herpesvirus 3 in two genetic lines of common carp Cyprinus carpio.

scientific article published on September 2014

Involvement of WSSV–shrimp homologs in WSSV infectivity in kuruma shrimp: Marsupenaeus japonicus ⬇️

scientific article published on September 6, 2010

Isolation and characterization of testis-specific DMRT1 in the tropical abalone (Haliotis asinina).

scientific article published on 10 December 2008

Isolation and molecular characterization of hemocyte sub-populations in kuruma shrimp Marsupenaeus japonicus

scientific article published on 30 March 2019

LAMP-1-chimeric DNA vaccines enhance the antibody response in Japanese flounder, Paralichthys olivaceus.

scientific article published on 17 June 2017

Linkage mapping of toll-like receptors (TLRs) in Japanese flounder, Paralichthys olivaceus.

scientific article

Microarray Analysis of Immunity Against WSSV in Response to Injection of Non-specific Long dsRNA in Kuruma Shrimp, Marsupenaeus japonicus.

scientific article published on 8 May 2015

Microarray analyses of shrimp immune responses.

scientific article published on August 2011

Microarray analysis of hepatic gene expression in juvenile Japanese flounder Paralichthys olivaceus fed diets supplemented with fish or vegetable oils.

scientific article

Microarray technology is an effective tool for identifying genes related to the aquacultural improvement of Japanese flounder, Paralichthys olivaceus.

scientific article

Molecular characterization and expression analysis of a c-type and two novel muramidase-deficient i-type lysozymes from Penaeus monodon

scientific article published on 15 January 2010

Molecular characterization and gene expression of a CXC chemokine gene from Japanese flounder Paralichthys olivaceus.

scientific article published on 20 July 2007

Molecular characterization and virulence gene profiling of pathogenic Streptococcus agalactiae populations from tilapia ( Oreochromis sp.) farms in Thailand.

scientific article published on 19 May 2014

Molecular characterization of Galectin-8 from Nile tilapia (Oreochromis niloticus Linn.) and its response to bacterial infection

scientific article published on 23 October 2015

Molecular characterization, expression and functional analysis of a nuclear oligomerization domain proteins subfamily C (NLRC) in Japanese flounder (Paralichthys olivaceus).

scientific article published on 27 May 2011

Molecular cloning and antiviral activity of IFN-β promoter stimulator-1 (IPS-1) gene in Japanese flounder, Paralichthys olivaceus.

scientific article published on 26 August 2010

Molecular cloning and characterization of Mj-mov-10, a putative RNA helicase involved in RNAi of kuruma shrimp.

scientific article published on 24 February 2015

Molecular cloning and characterization of Toll-like receptor 14 in Japanese flounder, Paralichthys olivaceus.

scientific article

Molecular cloning and characterization of Toll-like receptor 3 in Japanese flounder, Paralichthys olivaceus.

scientific article published on 19 December 2011

Molecular cloning and comparative responses of Toll-like receptor 22 following ligands stimulation and parasitic infection in yellowtail (Seriola lalandi).

scientific article published on 20 June 2015

Molecular cloning and expression analysis of NOD-like receptor 5 in Japanese flounder (Paralichthys olivaceus) after injection with two different formalin-killed pathogenic bacteria and poly (I:C).

scientific article published on 31 August 2016

Molecular cloning and expression analysis of interferon regulatory factor 10 (IRF10) in Japanese flounder, Paralichthys olivaceus.

scientific article published on 29 September 2010

Molecular cloning and functional analysis of nucleotide-binding oligomerization domain 1 (NOD1) in olive flounder, Paralichthys olivaceus.

scientific article published on 26 November 2011

Molecular cloning, characterization and gene expression analysis of aminolevulinic acid synthase in Litopenaeus vannamei

scientific article published on 01 February 2020

Molecular cloning, genomic organization and recombinant expression of a crustin-like antimicrobial peptide from black tiger shrimp Penaeus monodon.

scientific article published on 11 September 2007

Molecular mechanisms of the shrimp clotting system.

scientific article published on 05 October 2012

Molecular serotyping, virulence gene profiling and pathogenicity of Streptococcus agalactiae isolated from tilapia farms in Thailand by multiplex PCR.

scientific article published on 13 March 2017

Mycobacterium bovis BCG vaccine induces non-specific immune responses in Japanese flounder against Nocardia seriolae

scientific article published on 15 May 2012

Novel Chimeric Multiepitope Vaccine for Streptococcosis Disease in Nile Tilapia (Oreochromis niloticus Linn.).

scientific article published on 17 January 2020

Pathogen recognition of a novel C-type lectin from Marsupenaeus japonicus reveals the divergent sugar-binding specificity of QAP motif.

scientific article

Pathogenic potential of a collagenase gene from Aeromonas veronii.

scientific article

PmPPAE2, a new class of crustacean prophenoloxidase (proPO)-activating enzyme and its role in PO activation.

scientific article published on 20 September 2010

Production and efficacy of an Aeromonas hydrophila recombinant S-layer protein vaccine for fish

scientific article published on 20 March 2010

Protective efficacy and immune responses induced by a DNA vaccine encoding codon-optimized PPA1 against Photobacterium damselae subsp. piscicida in Japanese flounder.

scientific article published on 14 January 2015

RNA aptamers inhibit the growth of the fish pathogen viral hemorrhagic septicemia virus (VHSV).

scientific article

RNA-seq identifies integrin alpha of kuruma shrimp Marsupenaeus japonicus as a candidate molecular marker for phagocytic hemocytes

scientific article published on 16 December 2017

Rapid diagnosis of three shrimp RNA viruses using RT-PCR-DNA chromatography

scientific article published on 28 May 2018

Recombinant PirA-like toxin protects shrimp against challenge with Vibrio parahaemolyticus, the aetiological agent of acute hepatopancreatic necrosis disease.

scientific article

Role of Marsupenaeus japonicus crustin-like peptide against Vibrio penaeicida and white spot syndrome virus infection

scientific article published on 11 June 2014

Shrimp miRNAs regulate innate immune response against white spot syndrome virus infection.

scientific article

TLR21's agonists in combination with Aeromonas antigens synergistically up-regulate functional TLR21 and cytokine gene expression in yellowtail leucocytes.

scientific article

Teleostean IL11b exhibits complementing function to IL11a and expansive involvement in antibacterial and antiviral responses.

scientific article published on 6 June 2008

Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus kidney after Edwardsiella tarda formalin-killed cells

scientific article published in November 2016

Temperature-dependent regulation of gene expression in poly (I:C)-treated Japanese flounder, Paralichthys olivaceus.

scientific article

The effect of liposome-coated recombinant protein VP28 against white spot syndrome virus in kuruma shrimp, Marsupenaeus japonicus.

scientific article published on 4 September 2009

The immune functions of sessile hemocytes in three organs of kuruma shrimp Marsupenaeus japonicus differ from those of circulating hemocytes

scientific article published on 21 April 2018

Transcriptional profile of red seabream iridovirus in a fish model as revealed by viral DNA microarrays.

scientific article published on 29 March 2007

Transcriptional regulation of type I interferon gene expression by interferon regulatory factor-3 in Japanese flounder, Paralichthys olivaceus.

scientific article

Two hemocyte sub-populations of kuruma shrimp Marsupenaeus japonicus.

scientific article published on 3 February 2017

Uncovering the mechanisms of shrimp innate immune response by RNA interference.

scientific article published on 16 April 2010

Vaccine efficacy of Mycobacterium bovis BCG against Mycobacterium sp. infection in amberjack Seriola dumerili

scientific article published on 24 November 2010

Variable domain antibodies specific for viral hemorrhagic septicemia virus (VHSV) selected from a randomized IgNAR phage display library.

scientific article

Virulence of acute hepatopancreatic necrosis disease PirAB-like relies on secreted proteins not on gene copy number

scientific article published on 13 August 2016

WSV399, a viral tegument protein, interacts with the shrimp protein PmVRP15 to facilitate viral trafficking and assembly.

scientific article published on 29 January 2016

White spot syndrome virus (WSSV) suppresses penaeidin expression in Marsupenaeus japonicus hemocytes

scientific article published on 22 April 2018

White spot syndrome virus induces metabolic changes resembling the warburg effect in shrimp hemocytes in the early stage of infection

scientific article published on 5 October 2011

Whole genome analyses of marine fish pathogenic isolate, Mycobacterium sp. 012931.

scientific article published on 31 May 2014

Whole-Genome Sequence of Fish-Pathogenic Mycobacterium sp. Strain 012931, Isolated from Yellowtail (Seriola quinqueradiata).

scientific article published on 08 August 2013

Whole‐genome analysis of red sea bream iridovirus spread in 2021 in Japan provided epidemiological and viral traits insight

scientific article published on 21 July 2022

YHV-responsive gene expression under the influence of PmRelish regulation.

scientific article published on October 2015

cDNA cloning of the immunoglobulin heavy chain genes in banded houndshark Triakis scyllium

scientific article published on 3 August 2010

gyrA and parC associated with quinolone resistance in Vibrio anguillarum.

scientific article published in May 2008

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