List of works - Stephen G Pyne

1,2-Addition versus homoconjugate addition reactions of indoles and electron-rich arenes to α-cyclopropyl N-acyliminium ions: synthetic and computational studies

scientific article published on 01 July 2019

A Pharmacological Strategy Using Stemofoline for more Efficacious Chemotherapeutic Treatments Against Human Multidrug Resistant Leukemic Cells

scientific article published on 25 December 2018

A mild and general method for the synthesis of 5-substituted and 5,5-disubstituted fulleroprolines

scientific article published on 21 February 2008

A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain

scientific article published on 9 October 2013

A new xanthone and a biphenyl from the flower and twig extracts of Garcinia mckeaniana

scientific article published on 16 December 2019

A tocotrienol quinone dimer and xanthones from the leaf extract of Garcinia nigrolineata

scientific article published on 13 May 2019

Alkaloids and styryllactones from Goniothalamus cheliensis

scientific article published on 20 October 2018

Alkaloids from the roots of Stichoneuron caudatum and their acetylcholinesterase inhibitory activities

scientific article published on 07 March 2014

Amides and Flavonoids from the Fruit and Leaf Extracts of Melodorum siamensis

scientific article published on 29 January 2019

An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins.

scientific article published on 21 September 2007

Antibacterial Prenylated Isoflavonoids from the Stems of Millettia extensa

scientific article published on 14 August 2018

Antibacterial and Inhibitory Activities against Nitric Oxide Production of Coumaronochromones and Prenylated Isoflavones from Millettia extensa

scientific article published on 12 August 2019

Antibacterial and cytotoxic activities of phenolic constituents from the stem extracts of Spatholobus parviflorus

scientific article published on 26 December 2018

Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa.

scientific article published on 8 August 2014

Antimalarial Oxoprotoberberine Alkaloids from the Leaves of Miliusa cuneata.

scientific article published on March 2016

Antimalarial and cytotoxic activities of pregnene-type steroidal alkaloids from Holarrhena pubescens roots

scientific article published on 24 November 2017

Antioxidant neolignans from the twigs and leaves of Mitrephora wangii HU

scientific article published on 10 September 2018

Asymmetric synthesis of anti-1,2-amino alcohols via the Borono-Mannich reaction: a formal synthesis of (-)-swainsonine

scientific article

Binaphthyl scaffolded peptoids via ring-closing metathesis reactions and their anti-bacterial activities.

scientific article published on 18 April 2009

Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria.

scientific article published on 22 April 2015

Binaphthyl-anchored antibacterial tripeptide derivatives with hydrophobic C-terminal amino acid variations.

scientific article

Binaphthyl-based dicationic peptoids with therapeutic potential.

scientific article published in January 2010

Bioactive compounds from the roots of Strophioblachia fimbricalyx.

scientific article published on 27 June 2013

Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles targeting Clostridioides (Clostridium) difficile: Synthesis, antibacterial evaluation and an in vivo C. difficile infection model

scientific article published on 01 March 2019

Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles: synthesis, antibacterial evaluation and preliminary mechanism of action studies

scientific article published on 13 February 2019

Chemical diversity and anti-acne inducing bacterial potentials of essential oils from selected Elsholtzia species.

scientific article published on 26 October 2017

Concise synthesis of (-)-steviamine and analogues and their glycosidase inhibitory activities

scientific article published on 01 June 2013

Concise synthesis of α-substituted 2-benzofuranmethamines and other 2-subsituted benzofurans via α-substituted 2-benzofuranmethyl carbocation intermediates.

scientific article published on 11 January 2013

Corrected Structure of Natural Hyacinthacine C1 via Total Synthesis

scientific article published on 04 February 2019

Correction to Corrected Structure of Natural Hyacinthacine C1 via Total Synthesis

scientific article published on 21 April 2020

Coumarins and flavones from the fruit and root extracts of Micromelum integerrimum

scientific article published on 06 November 2018

Current and Ongoing Developments in Targeting Clostridioides difficile Infection and Recurrence

scientific article published on 15 June 2024

Dasymaschalolactams A-E, Aristolactams from a Twig Extract of Dasymaschalon dasymaschalum

scientific article published on 29 October 2019

Diastereoselective Ritter reactions of chiral cyclic N-acyliminium ions: synthesis of pyrido- and pyrrolo[2,3-d]oxazoles and 4-Hydroxy-5-N-acylaminopyrrolidines and 5-hydroxy-6-N-acylaminopiperidines.

scientific article

Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis. ⬇️

scientific article published on 4 August 2015

Divergent Pd-catalyzed cross-coupling of allenyloxazolidinones to give chiral 1,3-dienes and vinyloxazolidinones

scientific article published on 09 August 2019

Dual Gold-Catalyzed Cycloaromatization of Unconjugated (E)-Enediynes

scientific article published on 17 January 2019

Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities.

scientific article published on 28 June 2011

Five-membered cyclic sulfamidate imines: versatile scaffolds for organic synthesis

scientific article published on 15 September 2020

Four new C-benzyl flavonoids from the fruit of Uvaria cherrevensis

scientific article published on 27 August 2018

Fullerene Van der Waals Oligomers as Electron Traps

scientific article published on 24 July 2014

Highly diastereoselective synthesis of enantioenriched anti-α-allyl-β-fluoroamines

scientific article published on 08 May 2019

In vitro cytotoxicity evaluation of some substituted isatin derivatives.

scientific article published on 20 October 2006

Inhibition of TNF-α production in LPS-activated THP-1 monocytic cells by the crude extracts of seven Bhutanese medicinal plants.

scientific article published on 12 June 2013

Mallopenins A-E, Antibacterial Phenolic Derivatives from the Fruits of Mallotus philippensis

scientific article published on 18 July 2019

Metal-catalyzed cycloisomerization reactions of cis-4-hydroxy-5-alkynylpyrrolidinones and cis-5-hydroxy-6-alkynylpiperidinones: synthesis of furo[3,2-b]pyrroles and furo[3,2-b]pyridines.

scientific article published in August 2009

Modulation of P-glycoprotein by Stemona alkaloids in human multidrug resistance leukemic cells and structural relationships.

scientific article published on 3 August 2017

N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents.

scientific article published on 7 January 2008

Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio.

scientific article

Oxazolidinones and 2,5-Dihydrofurans via Zinc-Catalyzed Regioselective Allenylation Reactions of l-α-Amino Aldehydes.

scientific article published on 30 May 2017

Parviflorals A-F, trinorcadalenes and bis-trinorcadalenes from the roots of Decaschistia parviflora.

scientific article published on 10 August 2013

Phloroglucinol Benzophenones and Xanthones from the Leaves of Garcinia cowa and Their Nitric Oxide Production and α-Glucosidase Inhibitory Activities

scientific article published on 20 December 2019

Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids.

scientific article published on 4 November 2010

Phytochemical studies on Stemona aphylla: isolation of a new stemofoline alkaloid and six new stemofurans.

scientific article published on 2 December 2010

Phytochemical studies on Stemona plants: isolation of stemofoline alkaloids

scientific article published on 01 December 2005

Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis

scientific article published on 04 January 2019

Potent α-glucosidase inhibitory activity of compounds isolated from the leaf extracts of Uvaria hamiltonii

scientific article published on 23 December 2018

Regioselective and diastereoselective borono-Mannich reactions with pinacol allenylboronate

scientific article published on 05 February 2015

Resolution and identification of scalemic caged xanthones from the leaf extract of Garcinia propinqua having potent cytotoxicities against colon cancer cells

scientific article published on 12 October 2017

Reversal of human multi-drug resistance leukaemic cells by stemofoline derivatives via inhibition of P-glycoprotein function.

scientific article published on 24 October 2014

Scalemic Caged Xanthones Isolated from the Stem Bark Extract of Garcinia propinqua.

scientific article

Selective targeting of 2'-deoxy-5-fluorouridine to urokinase positive malignant cells in vitro.

scientific article published on 9 March 2010

Semisynthesis and acetylcholinesterase inhibitory activity of stemofoline alkaloids and analogues.

scientific article published in May 2010

Semisynthesis and biological activity of stemofoline alkaloids

scientific article published on 01 April 2009

Sequential 1,4- and 1,2-addition reactions to α,β-unsaturated N-acyliminium ions: a new strategy for the synthesis of spiro and bridged heterocycles.

scientific article published on 7 November 2013

Structural reassignment of the mono- and bis-addition products from the addition reactions of N-(Diphenylmethylene)glycinate esters to [60]fullerene under Bingel conditions

scientific article

Structural revision of stemoburkilline from an E-alkene to a Z-alkene

scientific article published on 01 February 2009

Synthesis and antibacterial activity of C2-symmetric binaphthyl scaffolded amino acid derivatives

scientific article published on 25 June 2011

Synthesis and antibacterial activity of some binaphthyl-supported macrocycles containing a cationic amino acid

scientific article published on 14 April 2011

Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 1.

scientific article published on 23 February 2010

Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 2.

scientific article published on 2 June 2010

Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics

scientific article published on 9 September 2015

Synthesis of (+)-uniflorine a: a structural reassignment and a configurational assignment

scientific article published on 03 June 2008

Synthesis of Bridged Heterocycles via Sequential 1,4- and 1,2-Addition Reactions to α,β-Unsaturated N-Acyliminium Ions: Mechanistic and Computational Studies.

scientific article published on 27 January 2016

Synthesis of hyacinthacine B3 and purported hyacinthacine B7.

scientific article published in December 2009

Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials.

scientific article published on 9 July 2008

Synthesis of spirocyclic heterocycles from α,β-unsaturated N-acyliminium ions

scientific article published on 16 November 2020

The Roots of Neorautanenia mitis (A. Rich) Verdcourt: Further Evidence of Its Antidiarrhoeal Activity

scientific article published on 9 January 2023

The discovery of allyltyrosine based tripeptides as selective inhibitors of the HIV-1 integrase strand-transfer reaction.

scientific article

The isolation of bioactive flavonoids from Jacaranda obtusifolia H. B. K. ssp. rhombifolia (G. F. W. Meijer) Gentry.

scientific article

Total Synthesis of Natural Hyacinthacine C5 and Six Related Hyacinthacine C5 Epimers.

scientific article

Total synthesis of hyacinthacines B₃, B₄, and B₅ and purported hyacinthacine B₇, 7-epi-hyacinthacine B₇, and 7a-epi-hyacinthacine B₃ from a common precursor

scientific article published on 05 May 2014

Two new bioactive iridoids from Rothmannia wittii.

scientific article published on 15 July 2016

Utilization of electrocoagulation for the isolation of alkaloids from the aerial parts of Stemona aphylla and their mosquitocidal activities against Aedes aegypti

scientific article published on 26 July 2019

Uvarialuridols A-C, three new polyoxygenated cyclohexenes from the twig and leaf extracts of Uvaria lurida

scientific article published on 26 August 2019

α-Glucosidase Inhibitory Flavonoids and Oxepinones from the Leaf and Twig Extracts of Desmos cochinchinensis

scientific article published on 05 March 2019

List of works by Stephen G Pyne

1,2-Addition versus homoconjugate addition reactions of indoles and electron-rich arenes to α-cyclopropyl N-acyliminium ions: synthetic and computational studies

A Pharmacological Strategy Using Stemofoline for more Efficacious Chemotherapeutic Treatments Against Human Multidrug Resistant Leukemic Cells

A mild and general method for the synthesis of 5-substituted and 5,5-disubstituted fulleroprolines

A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain

A new xanthone and a biphenyl from the flower and twig extracts of Garcinia mckeaniana

A tocotrienol quinone dimer and xanthones from the leaf extract of Garcinia nigrolineata

Alkaloids and styryllactones from Goniothalamus cheliensis

Alkaloids from the roots of Stichoneuron caudatum and their acetylcholinesterase inhibitory activities

Amides and Flavonoids from the Fruit and Leaf Extracts of Melodorum siamensis

An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins.

Antibacterial Prenylated Isoflavonoids from the Stems of Millettia extensa

Antibacterial and Inhibitory Activities against Nitric Oxide Production of Coumaronochromones and Prenylated Isoflavones from Millettia extensa

Antibacterial and cytotoxic activities of phenolic constituents from the stem extracts of Spatholobus parviflorus

Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa.

Antimalarial Oxoprotoberberine Alkaloids from the Leaves of Miliusa cuneata.

Antimalarial and cytotoxic activities of pregnene-type steroidal alkaloids from Holarrhena pubescens roots

Antioxidant neolignans from the twigs and leaves of Mitrephora wangii HU

Asymmetric synthesis of anti-1,2-amino alcohols via the Borono-Mannich reaction: a formal synthesis of (-)-swainsonine

Binaphthyl scaffolded peptoids via ring-closing metathesis reactions and their anti-bacterial activities.

Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria.

Binaphthyl-anchored antibacterial tripeptide derivatives with hydrophobic C-terminal amino acid variations.

Binaphthyl-based dicationic peptoids with therapeutic potential.

Bioactive compounds from the roots of Strophioblachia fimbricalyx.

Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles targeting Clostridioides (Clostridium) difficile: Synthesis, antibacterial evaluation and an in vivo C. difficile infection model

Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles: synthesis, antibacterial evaluation and preliminary mechanism of action studies

Chemical diversity and anti-acne inducing bacterial potentials of essential oils from selected Elsholtzia species.

Concise synthesis of (-)-steviamine and analogues and their glycosidase inhibitory activities

Concise synthesis of α-substituted 2-benzofuranmethamines and other 2-subsituted benzofurans via α-substituted 2-benzofuranmethyl carbocation intermediates.

Corrected Structure of Natural Hyacinthacine C1 via Total Synthesis

Correction to Corrected Structure of Natural Hyacinthacine C1 via Total Synthesis

Coumarins and flavones from the fruit and root extracts of Micromelum integerrimum

Current and Ongoing Developments in Targeting Clostridioides difficile Infection and Recurrence

Dasymaschalolactams A-E, Aristolactams from a Twig Extract of Dasymaschalon dasymaschalum

Diastereoselective Ritter reactions of chiral cyclic N-acyliminium ions: synthesis of pyrido- and pyrrolo[2,3-d]oxazoles and 4-Hydroxy-5-N-acylaminopyrrolidines and 5-hydroxy-6-N-acylaminopiperidines.

Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis. ⬇️

Divergent Pd-catalyzed cross-coupling of allenyloxazolidinones to give chiral 1,3-dienes and vinyloxazolidinones

Dual Gold-Catalyzed Cycloaromatization of Unconjugated (E)-Enediynes

Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities.

Five-membered cyclic sulfamidate imines: versatile scaffolds for organic synthesis

Four new C-benzyl flavonoids from the fruit of Uvaria cherrevensis

Fullerene Van der Waals Oligomers as Electron Traps

Highly diastereoselective synthesis of enantioenriched anti-α-allyl-β-fluoroamines

In vitro cytotoxicity evaluation of some substituted isatin derivatives.

Inhibition of TNF-α production in LPS-activated THP-1 monocytic cells by the crude extracts of seven Bhutanese medicinal plants.

Mallopenins A-E, Antibacterial Phenolic Derivatives from the Fruits of Mallotus philippensis

Metal-catalyzed cycloisomerization reactions of cis-4-hydroxy-5-alkynylpyrrolidinones and cis-5-hydroxy-6-alkynylpiperidinones: synthesis of furo[3,2-b]pyrroles and furo[3,2-b]pyridines.

Modulation of P-glycoprotein by Stemona alkaloids in human multidrug resistance leukemic cells and structural relationships.

N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents.

Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio.

Oxazolidinones and 2,5-Dihydrofurans via Zinc-Catalyzed Regioselective Allenylation Reactions of l-α-Amino Aldehydes.

Parviflorals A-F, trinorcadalenes and bis-trinorcadalenes from the roots of Decaschistia parviflora.

Phloroglucinol Benzophenones and Xanthones from the Leaves of Garcinia cowa and Their Nitric Oxide Production and α-Glucosidase Inhibitory Activities

Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids.

Phytochemical studies on Stemona aphylla: isolation of a new stemofoline alkaloid and six new stemofurans.

Phytochemical studies on Stemona plants: isolation of stemofoline alkaloids

Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis

Potent α-glucosidase inhibitory activity of compounds isolated from the leaf extracts of Uvaria hamiltonii

Regioselective and diastereoselective borono-Mannich reactions with pinacol allenylboronate

Resolution and identification of scalemic caged xanthones from the leaf extract of Garcinia propinqua having potent cytotoxicities against colon cancer cells

Reversal of human multi-drug resistance leukaemic cells by stemofoline derivatives via inhibition of P-glycoprotein function.

Scalemic Caged Xanthones Isolated from the Stem Bark Extract of Garcinia propinqua.

Selective targeting of 2'-deoxy-5-fluorouridine to urokinase positive malignant cells in vitro.

Semisynthesis and acetylcholinesterase inhibitory activity of stemofoline alkaloids and analogues.

Semisynthesis and biological activity of stemofoline alkaloids

Sequential 1,4- and 1,2-addition reactions to α,β-unsaturated N-acyliminium ions: a new strategy for the synthesis of spiro and bridged heterocycles.

Structural reassignment of the mono- and bis-addition products from the addition reactions of N-(Diphenylmethylene)glycinate esters to [60]fullerene under Bingel conditions

Structural revision of stemoburkilline from an E-alkene to a Z-alkene

Synthesis and antibacterial activity of C2-symmetric binaphthyl scaffolded amino acid derivatives

Synthesis and antibacterial activity of some binaphthyl-supported macrocycles containing a cationic amino acid

Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 1.

Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 2.

Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics

Synthesis of (+)-uniflorine a: a structural reassignment and a configurational assignment

Synthesis of Bridged Heterocycles via Sequential 1,4- and 1,2-Addition Reactions to α,β-Unsaturated N-Acyliminium Ions: Mechanistic and Computational Studies.

Synthesis of hyacinthacine B3 and purported hyacinthacine B7.

Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials.

Synthesis of spirocyclic heterocycles from α,β-unsaturated N-acyliminium ions

The Roots of Neorautanenia mitis (A. Rich) Verdcourt: Further Evidence of Its Antidiarrhoeal Activity

The discovery of allyltyrosine based tripeptides as selective inhibitors of the HIV-1 integrase strand-transfer reaction.