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List of works by Houcemeddine Othman

AaHIV a sodium channel scorpion toxin inhibits the proliferation of DU145 prostate cancer cells

scientific article published on 24 October 2019

An Integrative Computational Approach for the Prediction of Human-<i>Plasmodium</i> Protein-Protein Interactions

scientific article published on 19 December 2020

Anti-tumoral effect of scorpion peptides: Emerging new cellular targets and signaling pathways

scientific article published on 11 May 2019

Biochemical and monolayer characterization of Tunisian snake venom phospholipases.

scientific article

CDH1 Germline Variants in a Tunisian Cohort with Hereditary Diffuse Gastric Carcinoma

scientific article published on 23 February 2022

Characterization of Kbot21 Reveals Novel Side Chain Interactions of Scorpion Toxins Inhibiting Voltage-Gated Potassium Channels.

scientific article published on 23 September 2015

Functional and Structural Characterization of a Thermostable Phospholipase A2 from a Sparidae Fish (Diplodus annularis).

scientific article

Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides

scientific article published on 2 February 2018

G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19

scientific article published on 02 June 2020

Helix aspersa maxima mucus exhibits antimelanogenic and antitumoral effects against melanoma cells.

scientific article published on 22 March 2018

In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion.

scientific article published on 28 September 2016

Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: Similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism

scientific article published on 14 May 2020

Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism

scientific article (preprint)

Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression.

scientific article published on 29 January 2016

Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity to cisplatin.

scientific article published on 28 November 2017

N-glycosylation and homodimeric folding significantly enhance the immunoreactivity of Mycobacterium tuberculosis virulence factor CFP32 when produced in the yeast Pichia pastoris

scientific article published on 29 June 2019

PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells

scientific article

RK, the first scorpion peptide with dual disintegrin activity on αβ and αβ integrins

scientific article published on 01 October 2018

Targeting α1 inserted domain (I) of α1β1 integrin by Lebetin 2 from M. lebetina transmediterranea venom decreased tumorigenesis and angiogenesis

scientific article published on 02 June 2018

The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells

scientific article published in Scientific Reports

The galactolipase activity of Fusarium solani (phospho)lipase.

scientific article

Two distinct conformational states of Mycobacterium tuberculosis virulent factor early secreted antigenic target 6 kDa are behind the discrepancy around its biological functions.

scientific article

[Snake venom Kunitz/BPTI family: Structure, classification and pharmacological potential]

scientific article published on 01 January 2014