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List of works by Andrew Kellett

A new class of prophylactic metallo-antibiotic possessing potent anti-cancer and anti-microbial properties

scientific article published on 04 April 2019

A phosphate-targeted dinuclear Cu(II) complex combining major groove binding and oxidative DNA cleavage

scientific article published on 01 November 2018

Anti-Pseudomonas aeruginosa activity of 1,10-phenanthroline-based drugs against both planktonic- and biofilm-growing cells

scientific article published on 27 September 2015

Assessment of DNA Topoisomerase I Unwinding Activity, Radical Scavenging Capacity, and Inhibition of Breast Cancer Cell Viability of N-alkyl-acridones and N,N'-dialkyl-9,9'-biacridylidenes

scientific article published on 08 May 2019

Biological activity and coordination modes of copper(II) complexes of Schiff base-derived coumarin ligands.

scientific article published on 15 October 2010

Bis-phenanthroline copper(ii) phthalate complexes are potent in vitro antitumour agents with ‘self-activating’ metallo-nuclease and DNA binding properties

scientific article published on 16 December 2010

C 3-symmetric opioid scaffolds are pH-responsive DNA condensation agents

scientific article

Click and Cut: a click chemistry approach to developing oxidative DNA damaging agents

scientific article published on 01 October 2021

Copper bis-Dipyridoquinoxaline Is a Potent DNA Intercalator that Induces Superoxide-Mediated Cleavage via the Minor Groove

scientific article published on 26 November 2019

Copper phenanthrene oxidative chemical nucleases.

scientific article published on 7 May 2014

Copper(II) complexes of coumarin-derived Schiff bases and their anti-Candida activity.

scientific article published on 11 June 2009

Copper(II) complexes of salicylic acid combining superoxide dismutase mimetic properties with DNA binding and cleaving capabilities display promising chemotherapeutic potential with fast acting in vitro cytotoxicity against cisplatin sensitive and r

scientific article published on 28 February 2012

Cu(ii) phenanthroline-phenazine complexes dysregulate mitochondrial function and stimulate apoptosis

scientific article published on 01 January 2020

DNA cleavage reactions of the dinuclear chemotherapeutic agent copper(II) bis-1,10- phenanthroline terephthalate

scientific article published on 01 January 2012

DNA oxidation profiles of copper phenanthrene chemical nucleases

scientific article published on 21 April 2015

Di-copper metallodrugs promote NCI-60 chemotherapy via singlet oxygen and superoxide production with tandem TA/TA and AT/AT oligonucleotide discrimination

scientific article published on 21 February 2018

Efficient DNA Condensation by a C3 -Symmetric Codeine Scaffold

scientific article published on 13 December 2018

Frontispiece: Polypyridyl‐Based Copper Phenanthrene Complexes: A New Type of Stabilized Artificial Chemical Nuclease

Hexakis(prop-2-enamide)copper(II) bis(perchlorate) and hexakis(prop-2-enamide)manganese(II) bis(perchlorate).

scientific article published on 30 October 2010

In-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexes

scientific article published on 01 June 2018

Innovative DNA-Targeted Metallo-prodrug Strategy Combining Histone Deacetylase Inhibition with Oxidative Stress

scholarly article by Tadhg J. P. McGivern et al published 7 September 2018 in Molecular Pharmaceutics

Molecular methods for assessment of non-covalent metallodrug-DNA interactions

scientific article published on 01 February 2019

Polypyridyl‐Based Copper Phenanthrene Complexes: A New Type of Stabilized Artificial Chemical Nuclease

scientific article published on 27 November 2018

Potent oxidative DNA cleavage by the di-copper cytotoxin: [Cu2(μ-terephthalate)(1,10-phen)4]2+.

scientific article

Process-relevant concentrations of the leachable bDtBPP impact negatively on CHO cell production characteristics.

scientific article published on 24 August 2016

Protein engineering with artificial chemical nucleases

scientific article published on July 2015

Radical-induced DNA damage by cytotoxic square-planar copper(II) complexes incorporating o-phthalate and 1,10-phenanthroline or 2,2'-dipyridyl.

scientific article

Radical-induced purine lesion formation is dependent on DNA helical topology.

scientific article

Regulating bioactivity of Cu2+ bis-1,10-phenanthroline artificial metallonucleases with sterically functionalized pendant carboxylates.

scientific article published on 6 November 2013

Silver(I) complexes of 9-anthracenecarboxylic acid and imidazoles: synthesis, structure and antimicrobial activity.

scientific article published on 5 April 2012

Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH(2)) and 3,3-Dimethylpentanedioic acid(3dmepdaH(2)): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)](2). 6H(2)O and [Cu(2dm

scientific article published on 20 March 2006

Synthesis, X-ray crystal structures and biomimetic and anticancer activities of novel copper(II)benzoate complexes incorporating 2-(4'-thiazolyl)benzimidazole (thiabendazole), 2-(2-pyridyl)benzimidazole and 1,10-phenanthroline as chelating nitrogen

scientific article published on 14 February 2007

The phosphate clamp: sequence selective nucleic acid binding profiles and conformational induction of endonuclease inhibition by cationic Triplatin complexes

scientific article

Triggering autophagic cell death with a di-manganese(II) developmental therapeutic

scientific article published on 04 February 2017

Water-soluble and photo-stable silver(I) dicarboxylate complexes containing 1,10-phenanthroline ligands: Antimicrobial and anticancer chemotherapeutic potential, DNA interactions and antioxidant activity

scientific article published on 2 March 2016

Water-soluble bis(1,10-phenanthroline) octanedioate Cu2+ and Mn2+ complexes with unprecedented nano and picomolar in vitro cytotoxicity: promising leads for chemotherapeutic drug development

article

[Cu(o-phthalate)(phenanthroline)] Exhibits Unique Superoxide-Mediated NCI-60 Chemotherapeutic Action through Genomic DNA Damage and Mitochondrial Dysfunction

scientific article published on 21 October 2015

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