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List of works by David Tulasne

A novel viper venom metalloproteinase, alborhagin, is an agonist at the platelet collagen receptor GPVI.

scientific article published on 8 May 2001

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

scientific article published on 02 June 2016

Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling

scientific article (publication date: 14 June 2002)

Caspase Cleavages of the Lymphocyte-oriented Kinase Prevent Ezrin, Radixin, and Moesin Phosphorylation during Apoptosis.

scientific article published on 4 March 2016

Caspase cleavage of Ets-1 p51 generates fragments with transcriptional dominant-negative function

scientific article

Caspase cleavage of viral proteins, another way for viruses to make the best of apoptosis

scientific article published on 8 March 2012

Caspase-generated fragment of the Met receptor favors apoptosis via the intrinsic pathway independently of its tyrosine kinase activity.

scientific article published on 17 October 2013

Caspases shutdown nonsense-mediated mRNA decay during apoptosis

scientific article

Control of cell death/survival balance by the MET dependence receptor

scientific article published on 24 February 2020

Delineation of the region in the glycoprotein VI tail required for association with the Fc receptor gamma-chain

scientific article published on 7 July 2003

Exon 14 Deleted MET Receptor as a New Biomarker and Target in Cancers.

scientific article published on May 2017

Expression of GD3 synthase modifies ganglioside profile and increases migration of MCF-7 breast cancer cells

Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer

scientific article published on 29 March 2019

GD₃ synthase expression enhances proliferation and tumor growth of MDA-MB-231 breast cancer cells through c-Met activation

scientific article published on October 2010

HGF/SF regulates expression of apoptotic genes in MCF-10A human mammary epithelial cells.

scientific article published on December 2006

Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway

scientific article (publication date: 4 April 2002)

High-MET status in non-small cell lung tumors correlates with receptor phosphorylation but not with the serum level of soluble form.

scientific article published on 14 September 2016

How does met regulate the survival/apoptosis balance?

scientific article

Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI

scientific article (publication date: June 2002)

Involvement of RAS-ERK signaling in multiple biological responses to HGF/SF

scientific article published on 01 November 2002

Loss of a negative feedback loop involving pea3 and cyclin d2 is required for pea3-induced migration in transformed mammary epithelial cells

scientific article published on 29 August 2013

MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering

scientific article published on 04 January 2017

Necrosis- and apoptosis-related Met cleavages have divergent functional consequences

scientific article

Optimized approach for the identification of highly efficient correctors of nonsense mutations in human diseases

scientific article

Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection.

scientific article published on 11 January 2018

Outcome of EGFR-mutated NSCLC patients with MET-driven resistance to EGFR tyrosine kinase inhibitors.

scientific article published on 9 October 2017

PEA3 transcription factors are downstream effectors of Met signaling involved in migration and invasiveness of Met-addicted tumor cells.

scientific article published on 15 July 2015

Phosphorylation of the MET receptor on juxtamembrane tyrosine residue 1001 inhibits its caspase-dependent cleavage.

scientific article

Preferential Localization of MET Expression at the Invasion Front and in Spreading Cells Through Air Spaces in Non-Small Cell Lung Carcinomas

scientific article published on 16 January 2017

Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins

scientific article

Preparation and characterization of Zonyl-coated nanodiamonds with antifouling properties

scientific article published on 14 March 2011

Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage

scientific article

Proteolytic cleavages give receptor tyrosine kinases the gift of ubiquity.

scientific article published on June 2009

Regulation of RAS in human platelets

scientific article published on 01 March 2002

Regulation of the Ets-1 transcription factor by sumoylation and ubiquitinylation.

scientific article published on 24 July 2006

Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist.

scientific article published on 29 January 2015

Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells.

scientific article published on 9 June 2014

Tensin-4-dependent MET stabilization is essential for survival and proliferation in carcinoma cells

scientific article

The ETS1 transcription factor is expressed during epithelial-mesenchymal transitions in the chick embryo and is activated in scatter factor-stimulated MDCK epithelial cells.

scientific article published on June 1997

The Fc receptor gamma-chain is necessary and sufficient to initiate signalling through glycoprotein VI in transfected cells by the snake C-type lectin, convulxin

scientific article published on June 2002

The caspase-generated cleavage product of Ets-1 p51 and Ets-1 p27, Cp17, induces apoptosis

scientific article published on 10 October 2016

The dependence receptor TrkC triggers mitochondria-dependent apoptosis upon Cobra-1 recruitment

scientific article published on 01 September 2013

The ganglioside G(D2) induces the constitutive activation of c-Met in MDA-MB-231 breast cancer cells expressing the G(D3) synthase.

scientific article published in February 2012

The multiple paths towards MET receptor addiction in cancer.

scientific article published on 19 March 2018

The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering.

scientific article published on March 1999

The role of ITAM- and ITIM-coupled receptors in platelet activation by collagen

scientific article published on 01 July 2001

Thirty years of research on met receptor to move a biomarker from bench to bedside

scientific article

[MET receptor inhibition: Hope against resistance to targeted therapies?]

scientific article

[Thirty years of Met receptor research: from the discovery of an oncogene to the development of targeted therapies].

scientific article published on 14 October 2014