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List of works by Radek Pohl

13C GIAO DFT calculation as a tool for configuration prediction of N-O group in saturated heterocyclic N-oxides.

scientific article published on 27 April 2012

2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove.

scientific article published on 23 November 2016

4'-Alkoxy oligodeoxynucleotides: a novel class of RNA mimics

scientific article published on 03 November 2011

6-Aryl-4-amino-pyrimido[4,5-b]indole 2'-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study.

scientific article

A chiral dicationic [8]circulenoid: photochemical origin and facile thermal conversion into a helicene congener

scientific article published on 28 September 2012

A facile and efficient synthesis of (Purin-6-yl)alanines

scientific article published in November 2004

A general approach to optically pure [5]-, [6]-, and [7]heterohelicenes

scientific article published on 04 May 2012

Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2'-Deoxyadenosine, dATP and DNA

scientific article published on 14 October 2016

Additive Effects of Omega-3 Fatty Acids and Thiazolidinediones in Mice Fed a High-Fat Diet: Triacylglycerol/Fatty Acid Cycling in Adipose Tissue

scientific article published on 04 December 2020

Alkylsulfanylphenyl derivatives of cytosine and 7-deazaadenine nucleosides, nucleotides and nucleoside triphosphates: synthesis, polymerase incorporation to DNA and electrochemical study.

scientific article

Aminophenyl- and nitrophenyl-labeled nucleoside triphosphates: synthesis, enzymatic incorporation, and electrochemical detection

scientific article published in January 2008

An efficient method for the construction of functionalized DNA bearing amino acid groups through cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR

scientific article published on 01 January 2007

Anthraquinone as a redox label for DNA: synthesis, enzymatic incorporation, and electrochemistry of anthraquinone-modified nucleosides, nucleotides, and DNA.

scientific article

Aqueous Heck cross-coupling preparation of acrylate-modified nucleotides and nucleoside triphosphates for polymerase synthesis of acrylate-labeled DNA.

scientific article

Asymmetric domino aza-Michael addition/[3 + 2] cycloaddition reactions as a versatile approach to α,β,γ-triamino acid derivatives

scientific article published on 07 February 2014

Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA-protein interactions.

scientific article published on 16 September 2014

Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA-Protein Cross-Linking

scientific article published on 17 September 2015

Base-modified DNA labeled by [Ru(bpy)(3)](2+) and [Os(bpy)(3)](2+) complexes: construction by polymerase incorporation of modified nucleoside triphosphates, electrochemical and luminescent properties, and applications.

scientific article published in January 2009

Benzofurazane as a new redox label for electrochemical detection of DNA: towards multipotential redox coding of DNA bases

scientific article published on 9 August 2013

Bodipy-labeled nucleoside triphosphates for polymerase synthesis of fluorescent DNA.

scientific article

Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins

scientific article published in August 2016

Cleavage of functionalized DNA containing 5-modified pyrimidines by type II restriction endonucleases.

scientific article published on 14 January 2011

Conjugate addition of diethyl 1-fluoro-1-phenylsulfonylmethanephosphonate to α,β-unsaturated compounds

scientific article published on 22 April 2013

Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides

scientific article published in October 2016

Correction to "Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides"

scientific article published on 25 January 2019

Cross-coupling reaction of saccharide-based alkenyl boronic acids with aryl halides: the synthesis of bergenin

scientific article published on 3 March 2014

Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl)- and (purin-6-yl)phenylalanines

scientific article published in 2006

Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA

scientific article

Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides

scientific article published on September 2005

Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics.

scientific article published on 21 November 2017

Determination of the Nucleic Acid Adducts Structure at the Nucleoside/Nucleotide Level by NMR Spectroscopy

scientific article published on 13 January 2015

Diethyl fluoronitromethylphosphonate: synthesis and application in nucleophilic fluoroalkyl additions

scientific article published on 01 January 2014

Direct C-H arylation of purines: development of methodology and its use in regioselective synthesis of 2,6,8-trisubstituted purines

scientific article published on 01 November 2006

Direct C-H borylation and C-H arylation of pyrrolo[2,3-d]pyrimidines: synthesis of 6,8-disubstituted 7-deazapurines

scientific article published on 14 January 2009

Direct C-H sulfenylation of purines and deazapurines

scientific article published on 2 July 2013

Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose

scientific article published on 10 September 2015

Direct polymerase synthesis of reactive aldehyde-functionalized DNA and its conjugation and staining with hydrazines

scientific article published on 01 February 2010

Electrospray Ionization Mass Spectrometry Reveals an Unexpected Coupling Product in the Copper-Promoted Synthesis of Pyrazoles

article published in 2013

Emission color tuning in AlQ3 complexes with extended conjugated chromophores

scientific article published on 01 August 2003

Erratum: Structural revisions of small molecules reported to cross-link G-quadruplex DNA in vivo reveal a repetitive assignment error in the literature.

scientific article

Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity

scientific article published on 19 October 2007

Facile and efficient synthesis of 6-(hydroxymethyl)purines

scientific article published on 01 September 2004

Ferrocenyl helquats: unusual chiral organometallic nonlinear optical chromophores.

scientific article

Ferrocenylethynyl derivatives of nucleoside triphosphates: synthesis, incorporation, electrochemistry, and bioanalytical applications

scientific article published on 01 January 2007

Flexible double-headed cytosine-linked 2'-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases.

scientific article

Functional helquats: helical cationic dyes with marked, switchable chiroptical properties in the visible region

scientific article published on 01 January 2015

GFP-like fluorophores as DNA labels for studying DNA-protein interactions.

scientific article

Helquat Dyes: Helicene-like Push-Pull Systems with Large Second-Order Nonlinear Optical Responses.

scientific article published on 4 February 2016

Helquats: a facile, modular, scalable route to novel helical dications

scientific article published on 01 January 2009

Highly Functionalized Cyclopentane Derivatives by Tandem Michael Addition/Radical Cyclization/Oxygenation Reactions.

scientific article published on 26 May 2015

Highly functionalized and potent antiviral cyclopentane derivatives formed by a tandem process consisting of organometallic, transition-metal-catalyzed, and radical reaction steps.

scientific article published on 10 July 2014

Insights into the Mechanism of Action of Bactericidal Lipophosphonoxins

scientific article

Intramolecular direct C-H arylation approach to fused purines. Synthesis of purino[8,9-f]phenanthridines and 5,6-dihydropurino[8,9-a]isoquinolines

scientific article published in April 2010

Limitations in the description of conformational preferences of C-disaccharides: The (1 → 3)-C-mannobiose case

scientific article

Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents

scientific article published on 27 June 2017

Lipophosphonoxins: new modular molecular structures with significant antibacterial properties

scientific article published on 01 November 2011

Lithium salts of [1,12-dialkyl-CB11Me10]- anions.

scientific article published on 8 October 2010

Mekabu fucoidan: structural complexity and defensive effects against avian influenza A viruses

scientific article published on 23 May 2014

Microwave-assisted alkylation of [CB11H12]- and related anions

scientific article published on 11 October 2010

Modular Stereoselective Synthesis of (1→2)-C-Glycosides based on the sp(2) -sp(3) Suzuki-Miyaura Reaction.

scientific article

Modular and practical synthesis of 6-substituted pyridin-3-yl C-nucleosides

scientific article published on 01 August 2007

Modular synthesis of 5-substituted thiophen-2-yl C-2'-deoxyribonucleosides

scientific article published on 17 April 2008

Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor

scientific article

N(4)-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: chemistry and antiviral activity

scientific article published on 26 March 2014

N-Branched acyclic nucleoside phosphonates as monomers for the synthesis of modified oligonucleotides.

scientific article

N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase.

scientific article published on 13 February 2012

Observed and calculated 1H and 13C chemical shifts induced by the in situ oxidation of model sulfides to sulfoxides and sulfones.

scientific article published on September 2010

Oxidative catalysis using the stoichiometric oxidant as a reagent: an efficient strategy for single-electron-transfer-induced tandem anion-radical reactions.

scientific article published on 28 July 2014

Oxidative radical cyclizations of diketopiperazines bearing an amidomalonate unit. Heterointermediate reaction sequences toward the asperparalines and stephacidins

scientific article published on 02 November 2016

Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA.

scientific article published on 9 August 2017

Phosphonoxins: rational design and discovery of a potent nucleotide anti-Giardia agent

scientific article published on 25 February 2007

Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides.

scientific article published on 4 December 2010

Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins.

scientific article

Polymerase synthesis of DNAs bearing vinyl groups in the major groove and their cleavage by restriction endonucleases

scientific article published in September 2014

Preparation of highly substituted 6-arylpurine ribonucleosides by Ni-catalyzed cyclotrimerization. Scope of the reaction

scientific article published on 01 November 2006

Proton transfer in guanine-cytosine base pair analogues studied by NMR spectroscopy and PIMD simulations

scientific article published on 01 December 2018

Purines Bearing Phenanthroline or Bipyridine Ligands and Their RuII Complexes in Position 8 as Model Compounds for Electrochemical DNA Labeling – Synthesis, Crystal Structure, Electrochemistry, Quantum Chemical Calculations, Cytostatic and Antivira

article

Pyrrolidine nucleotide analogs with a tunable conformation.

scientific article published on 22 August 2014

Regioselective direct C-H arylations of protected uracils. Synthesis of 5- and 6-aryluracil bases

scientific article published on 26 May 2011

Resolving Electronic Transitions in Synthetic Fluorescent Protein Chromophores by Magnetic Circular Dichroism

scientific article published on 28 April 2016

Sequential Oxidative and Reductive Radical Cyclization Approach toward Asperparaline C and Synthesis of Its 8-Oxo Analogue

scientific article published on 16 February 2017

Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions.

scientific article

Stepwise triple-click functionalization of synthetic peptides

scientific article published on 01 August 2018

Structural Features and Anti-coagulant Activity of the Sulphated Polysaccharide SPS-CF from a Green Alga Capsosiphon fulvescens.

scientific article

Structural analysis and anti-obesity effect of a pectic polysaccharide isolated from Korean mulberry fruit Oddi (Morus alba L.).

scientific article

Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides

scientific article

Structural revisions of small molecules reported to cross-link G-quadruplex DNA in vivo reveal a repetitive assignment error in the literature

scientific article published on 23 March 2016

Sugar modified pyrimido[4,5-]indole nucleosides: synthesis and antiviral activity

scientific article published on 25 August 2017

Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2'-C-methylribonucleosides, 2'-deoxy-2'-fluoroarabinonucleosides, arabinonucleosides and 2'-deoxyribonucleosides

scientific article

Syntheses of 1-[2-(Phosphonomethoxy)Alkyl]Thymine Monophosphates and an Evaluation of their Inhibitory Activity Toward Human Thymidine Phosphorylase ⬇️

scientific article published on January 1, 2012

Syntheses of N3-substituted thymine acyclic nucleoside phosphonates and a comparison of their inhibitory effect towards thymidine phosphorylase

scientific article published on 8 January 2008

Syntheses of pyrimidine acyclic nucleoside phosphonates as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma

scientific article published on January 2007

Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.

scientific article published on 21 February 2017

Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides

scientific article published on 10 April 2020

Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides

scientific article published on 3 October 2018

Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides

scientific article

Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides.

scientific article published on 17 June 2013

Synthesis and biological evaluation of acyclic nucleotide analogues with a furo[2,3-d]pyrimidin-2(3H)-one base

Synthesis and photophysical properties of 7-deaza-2'-deoxyadenosines bearing bipyridine ligands and their Ru(II)-complexes in position 7.

scientific article

Synthesis and photophysical properties of biaryl-substituted nucleos(t)ides. Polymerase synthesis of DNA probes bearing solvatochromic and pH-sensitive dual fluorescent and 19F NMR labels.

scientific article

Synthesis of 2'-deoxyadenosine nucleosides bearing bipyridine-type ligands and their Ru-complexes in position 8 through cross-coupling reactions.

scientific article published on 31 July 2007

Synthesis of 6,8,9-tri- and 2,6,8,9-tetrasubstituted purines by a combination of the Suzuki cross-coupling, N-arylation, and direct C-H arylation reactions

scientific article

Synthesis of 8-bromo-, 8-methyl- and 8-phenyl-dATP and their polymerase incorporation into DNA.

scientific article

Synthesis of C-aryldeoxyribosides by [2 + 2 + 2]-cyclotrimerization catalyzed by Rh, Ni, Co, and Ru complexes

scientific article published on 01 May 2006

Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism

scientific article published on 23 January 2017

Synthesis of acetylene linked double-nucleobase nucleos(t)ide building blocks and polymerase construction of DNA containing cytosines in the major groove

scientific article published on 22 March 2011

Synthesis of aldehyde-linked nucleotides and DNA and their bioconjugations with lysine and peptides through reductive amination.

scientific article published on 15 February 2012

Synthesis of alkylcarbonate analogs of O-acetyl-ADP-ribose.

scientific article published in September 2013

Synthesis of bridged diketopiperazines by using the persistent radical effect and a formal synthesis of bicyclomycin

scientific article published on 25 August 2015

Synthesis of enantiomerically pure (purin-6-yl)phenylalanines and their nucleosides, a novel type of purine-amino acid conjugates

scientific article published in September 2005

Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents

scientific article published on October 2010

Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA.

scientific article published on 15 January 2010

Synthesis of nucleoside mono- and triphosphates bearing oligopyridine ligands, their incorporation into DNA and complexation with transition metals

scientific article published on 09 November 2011

Synthesis of nucleosides and dNTPs bearing oligopyridine ligands linked through an octadiyne tether, their incorporation into DNA and complexation with transition metal cations

Synthesis of oligoribonucleotides with phosphonate-modified linkages

scientific article published on 18 July 2011

Synthesis of racemic and enantiomeric 3-pyrrolidinyl derivatives of purine and pyrimidine nucleobases.

scientific article

Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations

scientific article

Synthesis, Photophysical Properties and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides

scientific article published on 20 May 2020

Synthesis, conformational studies, and biological properties of phosphonomethoxyethyl derivatives of nucleobases with a locked conformation via a pyrrolidine ring.

scientific article

Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides

scientific article published on 29 November 2007

Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides

scientific article published on 23 October 2007

Tetrathiafulvalene-oligo(para-phenyleneethynylene) conjugates: formation of multiple mixed-valence complexes upon electrochemical oxidation.

scientific article published on 13 March 2013

The 16 CB11(CH3)n(CD3)(12-n)• radicals with 5-fold substitution symmetry: spin density distribution in CB11Me12(•)

scientific article published on 20 September 2012

The determination of sulfoxide configuration in five-membered rings using NMR spectroscopy and DFT calculations

The discovery of pyridinium 1,2,4-triazines with enhanced performance in bioconjugation reactions

scientific article published on 01 March 2017

The first direct C-H arylation of purine nucleosides

scientific article published on 25 October 2007

The first synthesis and cytostatic activity of novel 6-(fluoromethyl)purine bases and nucleosides

scientific article published on 4 July 2005

The observed and calculated 1H and 13C chemical shifts of tertiary amines and their N-oxides.

scientific article published on 31 March 2011

The use of cobalt-mediated cycloisomerisation of ynedinitriles in the synthesis of pyridazinohelicenes.

scientific article published on 30 May 2014

Total syntheses of all tri-oxygenated 16-phytoprostane classes via a common precursor constructed by oxidative cyclization and alkyl-alkyl coupling reactions as the key steps.

scientific article published on 2 November 2017

Transient and switchable (triethylsilyl)ethynyl protection of DNA against cleavage by restriction endonucleases

scientific article published on 29 July 2011

Tricyclic etheno analogs of PMEG and PMEDAP: Synthesis and biological activity

scientific article published in 2006

Trifluoroacetophenone-Linked Nucleotides and DNA for Studying of DNA-Protein Interactions by 19F NMR Spectroscopy

scientific article

Tunable Chiral Second-Order Nonlinear Optical Chromophores Based on Helquat Dications.

scientific article published on 13 July 2017

Utilization of 1,3-Dioxolanes in the Synthesis of α-branched Alkyl and Aryl 9-[2-(Phosphonomethoxy)Ethyl]Purines and Study of the Influence of α-branched Substitution for Potential Biological Activity

scientific article published on 07 December 2018

Vinylsulfonamide and acrylamide modification of DNA for cross-linking with proteins

scientific article published on 12 August 2013

[2+2+2] Cycloisomerisation of Aromatic Cyanodiynes in the Synthesis of Pyridohelicenes and Their Analogues.

scientific article

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