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List of works by Geert Molenberghs

A Bayesian, generalized frailty model for comet assays

scientific article published in May 2013

A Flexible Method to Measure Synchrony in Neuronal Firing

A bivariate pseudolikelihood for incomplete longitudinal binary data with nonignorable nonmonotone missingness

scientific article

A closed-form estimator for meta-analysis and surrogate markers evaluation

scientific article published on 26 October 2018

A clustering algorithm for multivariate longitudinal data

scientific article

A comparison of doubly hierarchical discriminant analyses for multiple class longitudinal data from EEG experiments

scientific article

A generalized Poisson-gamma model for spatially overdispersed data

scientific article

A hierarchical Binomial-Poisson model for the analysis of a crossover design for correlated binary data when the number of trials is dose-dependent

scientific article

A hierarchical modeling approach for risk assessment in developmental toxicity studies

article

A high-dimensional joint model for longitudinal outcomes of different nature

scientific article published in September 2008

A joint model for hierarchical continuous and zero-inflated overdispersed count data

A joint model for longitudinal continuous and time-to-event outcomes with direct marginal interpretation

scientific article

A latent pharmacokinetic time profile to model dose-response survival data

scientific article

A latent-class mixture model for incomplete longitudinal Gaussian data

scientific article

A local influence approach applied to binary data from a psychiatric study

scientific article

A local influence approach to sensitivity analysis of incomplete longitudinal ordinal data

A local influence sensitivity analysis for incomplete longitudinal depression data

scientific article published in May 2006

A maximum entropy approach for the evaluation of surrogate endpoints based on causal inference

scientific article published on 23 August 2018

A modeling approach to the analysis of nerve regenerative experiments

scientific article published in January 2006

A multilevel model for hierarchical, repeated, and overdispersed time-to-event outcomes and its estimation strategies

scientific article

A multiple-imputation-based approach to sensitivity analyses and effectiveness assessments in longitudinal clinical trials

scientific article published in January 2014

A new modeling approach for quantifying expert opinion in the drug discovery process

scientific article published on 23 February 2015

A nonparametric approach to weighted estimating equations for regression analysis with missing covariates

article

A perspective on surrogate endpoints in controlled clinical trials

scientific article published on June 2004

A portfolio-based approach to optimize proof-of-concept clinical trials

scientific article published in January 2012

A reflection on the causal interpretation of individual-level surrogacy

scientific article published on 16 February 2019

A reflection on the possibility of finding a good surrogate

scientific article published on 26 January 2019

A sensitivity analysis for shared-parameter models for incomplete longitudinal outcomes

scientific article published on February 2010

A structured approach to choosing estimands and estimators in longitudinal clinical trials ⬇️

scientific article published on September 10, 2012

A unified framework for the evaluation of surrogate endpoints in mental-health clinical trials

scientific article published on 16 July 2009

A unifying approach for surrogate marker validation based on Prentice's criteria

scientific article

A weighted combination of pseudo-likelihood estimators for longitudinal binary data subject to non-ignorable non-monotone missingness

scientific article

A zero-inflated overdispersed hierarchical Poisson model

Accounting for variability in individual hierarchical clinical trial data

scientific article

Adaptive change-point mixed models applied to data on outpatient tetracycline use in Europe

Alternative methods to evaluate trial level surrogacy

scientific article published in January 2008

An efficient algorithm to assess multivariate surrogate endpoints in a causal inference framework

scientific article published in 2022

An equivalence test for comparing DNA sequences

An evaluation of the trimmed mean approach in clinical trials with dropout

scientific article published on 6 April 2018

An extended random-effects approach to modeling repeated, overdispersed count data

scientific article

An information-theoretic approach for the evaluation of surrogate endpoints based on causal inference

scientific article

An information-theoretic approach to surrogate-marker evaluation with failure time endpoints ⬇️

scientific article published on September 28, 2010

An information‐theoretic approach for the assessment of a continuous outcome as a surrogate for a binary true endpoint based on causal inference: Application to vaccine evaluation

scientific article published in 2024

Analysing the composition of outpatient antibiotic use: a tutorial on compositional data analysis

scientific article

Analysis of an incomplete binary outcome derived from frequently recorded longitudinal continuous data: application to daily pain evaluation ⬇️

scientific article published on February 23, 2012

Analysis of non-ignorable missing and left-censored longitudinal data using a weighted random effects tobit model

scientific article

Analyzing incomplete longitudinal clinical trial data

scientific article

Application of mixed-effects models to study the country-specific outpatient antibiotic use in Europe: a tutorial on longitudinal data analysis

scientific article

Application of penalized splines in analyzing neuronal data

scientific article

Application of semiparametric mixed models and simultaneous confidence bands in a cardiovascular safety experiment with longitudinal data

scientific article

Applying concepts of generalizability theory on clinical trial data to investigate sources of variation and their impact on reliability

scientific article

Applying linear mixed models to estimate reliability in clinical trial data with repeated measurements

scientific article

Assessing and interpreting treatment effects in longitudinal clinical trials with missing data ⬇️

scientific article published on April 15, 2003

Assessment of type I error rate associated with dose-group switching in a longitudinal Alzheimer trial

scientific article

Attitudes and stigma in relation to help-seeking intentions for psychological problems in low and high suicide rate regions ⬇️

scientific article published on July 30, 2013

Bayesian testing for trend in a power model for clustered binary data

scientific article published in 2004

Behavioral testing of antidepressant compounds: an analysis of crossover design for correlated binary data

scientific article published in June 2005

Biometry, biometrics, biostatistics, bioinformatics,..., bio-X.

scientific article published in March 2005

Characteristics of heart, arteries, and veins in low and high cardiac output preeclampsia ⬇️

scientific article published on April 20, 2013

Choice of units of analysis and modeling strategies in multilevel hierarchical models

Choosing estimands in clinical trials with missing data

scientific article

Cluster analysis for repeated data with dropout: Sensitivity analysis using a distal event.

scientific article

Clustering multiply imputed multivariate high-dimensional longitudinal profiles

scientific article published on 24 April 2017

Combined models for data from in vitro-in vivo correlation experiments

scientific article

Comment on "Sexual maturation in relation to polychlorinated aromatic hydrocarbons: Sharpe and Skakkebaek's hypothesis revisited"

scientific article

Comparison of methods for the selection of genomic biomarkers

scientific article

Comparison of risks of cardiovascular events in the elderly using standard survival analysis and multiple-events and recurrent-events methods

scientific article

Comparison of the guaranteed analysis with the measured nutrient composition of commercial pet foods

scientific article

Conditional mixed models with crossed random effects

scientific article published in November 2007

Conflicts of interest and independent data analysis in industry-funded studies

scientific article

Correction for model selection bias using a modified model averaging approach for supervised learning methods applied to EEG experiments

scientific article

Cross nearest-spike interval based method to measure synchrony dynamics

scientific article

Detecting influential observations in a model-based cluster analysis

scientific article

Direct likelihood analysis versus simple forms of imputation for missing data in randomized clinical trials

scientific article

Diurnal and position-induced variability of impedance cardiography measurements in healthy subjects

scientific article published on 25 November 2010

Do inter-hospital comparisons of in-hospital, acute myocardial infarction case-fatality rates serve the purpose of fostering quality improvement? An evaluative study

scientific article

Doubly robust and multiple-imputation-based generalized estimating equations

scientific article published in March 2011

Dynamic manganese-enhanced MRI signal intensity processing based on nonlinear mixed modeling to study changes in neuronal activity

Dynamic predictions with time-dependent covariates in survival analysis using joint modeling and landmarking

scientific article published on 09 August 2017

Editorial "Joint modeling of longitudinal and time-to-event data and beyond".

scientific article

Efficacy of daily intake of Lactobacillus casei Shirota on respiratory symptoms and influenza vaccination immune response: a randomized, double-blind, placebo-controlled trial in healthy elderly nursing home residents

article

Empirical Bayes Estimates for Correlated Hierarchical Data with Overdispersion

scientific article

Establishing normative data for multi-trial memory tests: the multivariate regression-based approach

scientific article

Establishing normative data for repeated cognitive assessment: a comparison of different statistical methods

scientific article

Estimating reliability and generalizability from hierarchical biomedical data

scientific article

Estimating the causal effect of compliance on binary outcome in randomized controlled trials ⬇️

scientific article published on February 15, 1998

Estimation of the Force of Infection from Current Status Data Using Generalized Linear Mixed Models

article published in 2007

European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe (1997-2009).

scientific article

European Surveillance of Antimicrobial Consumption (ESAC): outpatient cephalosporin use in Europe (1997-2009).

scientific article

European Surveillance of Antimicrobial Consumption (ESAC): outpatient macrolide, lincosamide and streptogramin (MLS) use in Europe (1997-2009).

scientific article published in December 2011

European Surveillance of Antimicrobial Consumption (ESAC): outpatient penicillin use in Europe (1997-2009).

scientific article published in December 2011

European Surveillance of Antimicrobial Consumption (ESAC): outpatient quinolone use in Europe (1997-2009).

scientific article published in December 2011

European Surveillance of Antimicrobial Consumption (ESAC): outpatient use of tetracyclines, sulphonamides and trimethoprim, and other antibacterials in Europe (1997-2009).

scientific article published in December 2011

Evaluation of biomarkers for pharmacological activity

scientific article published in January 2009

Evaluation of chromogenic media for detection of methicillin-resistant Staphylococcus aureus

scientific article

Evaluation of molecular assays for rapid detection of methicillin-resistant Staphylococcus aureus

scientific article published on 13 October 2010

Evaluation of six months sputum culture conversion as a surrogate endpoint in a multidrug resistant-tuberculosis trial

scientific article published in PLoS ONE

Exploring the relationship between the causal-inference and meta-analytic paradigms for the evaluation of surrogate endpoints

scientific article published on 26 November 2015

Fast and highly efficient pseudo-likelihood methodology for large and complex ordinal data

scientific article

Fast precision estimation in high-dimensional multivariate joint models

scientific article published on 16 June 2017

Flexible modelling of neuron firing rates across different experimental conditions: an application to neural activity in the prefrontal cortex during a discrimination task

Functionally Unidimensional Item Response Models for Multivariate Binary Data

scientific article

Generalizability in nongaussian longitudinal clinical trial data based on generalized linear mixed models

scientific article

Generalized pairwise comparison methods to analyze (non)prioritized composite endpoints

scientific article published on 28 October 2019

Generalized reliability estimation using repeated measurements

scientific article published in May 2006

Generalized shared-parameter models and missingness at random

Graphical exploration of gene expression data: a comparative study of three multivariate methods

scientific article

Handling of missing data in long-term clinical trials: a case study

scientific article

Help-seeking, stigma and attitudes of people with and without a suicidal past. A comparison between a low and a high suicide rate country

scientific article published on 21 February 2015

Heterogeneity of symptom pattern, psychosocial factors, and pathophysiological mechanisms in severe functional dyspepsia

scientific article

High dimensional surrogacy: computational aspects of an upscaled analysis

scientific article published on 28 August 2019

Ignoring overdispersion in hierarchical loglinear models: Possible problems and solutions

scientific article

Impact of selection bias on the evaluation of clusters of chemical compounds in the drug discovery process

scientific article published on 25 November 2014

Impedance cardiography in uncomplicated pregnancy and pre-eclampsia: A reliability study ⬇️

scientific article published on October 1, 2012

Including information on the therapeutic window in bioequivalence acceptance

scientific article published on 18 July 2008

Incomplete hierarchical data

scientific article

Inferential Implications of Over-Parametrization: A Case Study in Incomplete Categorical Data

Information-theory based surrogate marker evaluation from several randomized clinical trials with continuous true and binary surrogate endpoints

scientific article published on January 2007

Introducing the Multivariate Dale Model in Population-Based Genetic Association Studies

Investigating association between behavior, corticosterone, heart rate, and blood pressure in rats using surrogate marker evaluation methodology

scientific article published in January 2009

Investigating the criterion validity of psychiatric symptom scales using surrogate marker validation methodology

scientific article published on May 2002

Joint modeling of hierarchically clustered and overdispersed non-gaussian continuous outcomes for comet assay data

scientific article

Joint modeling of multiple ordinal adherence outcomes via generalized estimating equations with flexible correlation structure.

scientific article published on 13 December 2017

Kernel weighted influence measures

article published in 2005

Last observation carried forward: a crystal ball?

scientific article published on September 2009

Lessons learned from IDeAl - 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials.

scientific article

Likelihood Ratio, Score, and Wald Tests in a Constrained Parameter Space

article by Geert Molenberghs & Geert Verbeke published February 2007 in The American Statistician

Marginalized multilevel hurdle and zero-inflated models for overdispersed and correlated count data with excess zeros

scientific article

Maternal and peer attachment, identity formation, and non-suicidal self-injury: a longitudinal mediation study

Maternal venous hemodynamics in gestational hypertension and preeclampsia

scientific article

Measurement agreement of the self-administered questionnaire of the Belgian Health Interview Survey: Paper-and-pencil versus web-based mode.

scientific article

Measuring trends of outpatient antibiotic use in Europe: jointly modelling longitudinal data in defined daily doses and packages

scientific article

Microbial Performance of Food Safety Control and Assurance Activities in a Fresh Produce Processing Sector Measured Using a Microbial Assessment Scheme and Statistical Modeling

scientific article

Missing data methods in longitudinal studies: a review

scientific article (publication date: May 2009)

Mixed models approaches for joint modeling of different types of responses

scientific article published on 22 June 2015

Model-based estimates of long-term persistence of induced HPV antibodies: a flexible subject-specific approach

scientific article published on January 2013

Modeling actor and partner effects in dyadic data when outcomes are categorical

scientific article

Modeling anti-KLH ELISA data using two-stage and mixed effects models in support of immunotoxicological studies

scientific article

Modeling combined continuous and ordinal outcomes in a clustered setting

Modelling associations between time-to-event responses in pilot cancer clinical trials using a Plackett-Dale model

scientific article published in July 2004

Modelling forces of infection by using monotone local polynomials

Multicollinearity in prognostic factor analyses using the EORTC QLQ-C30: identification and impact on model selection

scientific article published in December 2002

Multinomial additive hazard model to assess the disability burden using cross-sectional data

scientific article

Multiple-imputation-based residuals and diagnostic plots for joint models of longitudinal and survival outcomes

scientific article published on 18 May 2009

Non-linear Models for Longitudinal Data

scientific article

Norman Breslow's leadership for the international biometric society

scientific article

Occurrence of both bladder and prostate cancer in five cancer registries in Belgium, The Netherlands and the United Kingdom

scientific article published on 24 May 2007

On random sample size, ignorability, ancillarity, completeness, separability, and degeneracy: sequential trials, random sample sizes, and missing data

scientific article

On the relationship between association and surrogacy when both the surrogate and true endpoint are binary outcomes

scientific article published on 01 September 2020

On the relationship between the causal-inference and meta-analytic paradigms for the validation of surrogate endpoints

scientific article

On using multiple imputation for exploratory factor analysis of incomplete data

scientific article published on 31 January 2018

PP070. Maternal cardiovascular profiling in the first trimester ofpregnancies complicated with gestation induced hypertension or fetal growth restriction

scientific article

PP078. The influence of maternal position on gestational hemodynamics

scientific article

Parametric overdispersed frailty models for current status data

scientific article

Perinatal outcome of 12,021 singleton and 3108 twin births after non-IVF-assisted reproduction: a cohort study

scientific article published on 8 December 2005

Perinatal outcome of ICSI pregnancies compared with a matched group of natural conception pregnancies in Flanders (Belgium): a cohort study

scientific article published in August 2005

Predicting pregnancy rate and live birth rate in the IVF clinic by analysing patient profiles.

scientific article published on 17 September 2015

Prediction of survival and opportunistic infections in HIV-infected patients: a comparison of imputation methods of incomplete CD4 counts

scientific article published on May 2002

Predictors of oligoamenorrhea at 1-year follow-up in premenopausal women using a levonorgestrel-releasing intrauterine system

scientific article published on 22 June 2007

Premature discontinuation during the UPLIFT study

scientific article

Properties of Estimators in Exponential Family Settings with Observation-based Stopping Rules

scientific article

Pseudo-likelihood estimation for a marginal multivariate survival model

scientific article published in March 2004

Random effects models for estimation of the probability and time to progression of a continuous biomarker

scientific article published on 15 July 2019

Reliability measures in item response theory: manifest versus latent correlation functions

scientific article published on 3 February 2014

Remote Monitoring of Hypertension Diseases in Pregnancy: A Pilot Study

scientific article published on 09 March 2017

Response to comments on "Marginalized multilevel hurdle and zero-inflated models for overdispersed and correlated count data with excess zeros".

scientific article published in May 2018

Sample substitution can be an acceptable data-collection strategy: the case of the Belgian Health Interview Survey

scientific article published on 3 May 2017

Screening for inter-hospital differences in cesarean section rates in low-risk deliveries using administrative data: an initiative to improve the quality of care

scientific article

Secondary stroke prevention: misguided by guidelines? ⬇️

scientific article published on August 1, 2012

Selection models and pattern-mixture models to analyse longitudinal quality of life data subject to drop-out

scientific article

Semi-parametric Bayesian analysis of binary responses with a continuous covariate subject to non-random missingness

article

Sensitivity analysis for incomplete continuous data

article published in 2010

Sensitivity analysis for pattern mixture models

scientific article

Serial correlation structures in latent linear mixed models for analysis of multivariate longitudinal ordinal responses

scientific article published on 28 October 2020

Simplified hierarchical linear models for the evaluation of surrogate endpoints

Spatial analysis of breast and cervical cancer incidence in small geographical areas in Cuba, 1999-2003.

scientific article published in September 2009

Statistical Validation of Surrogate Endpoints: Problems and Proposals

Statistical Validation of Surrogate Markers in Clinical Trials

Statistical challenges in the evaluation of surrogate endpoints in randomized trials

scientific article

Statistical evaluation of surrogate endpoints with examples from cancer clinical trials

scientific article

Statistical models for analyzing repeated quality measurements of horticultural products. Model evaluations and practical example

scientific article published in October 2003

Statistical software for calculating properly weighted estimates from Health Interview Survey Data

scientific article

Stigma, Attitudes, and Help-Seeking Intentions for Psychological Problems in Relation to Regional Suicide Rates

scientific article published on 24 July 2015

Surrogate end points: hopes and perils

scientific article published on June 2008

Teaching statistical thinking to life scientists a case-based approach

scientific article published in January 2006

Testing for misspecification in generalized linear mixed models

scientific article published on 20 April 2010

Tests for Homogeneity of the Risk Difference when Data are Sparse

scientific article published on March 1, 1998

The Effect of Transborder Mobility on COVID-19 Incidences in Belgium

scientific article published on 12 August 2022

The Effective Sample Size and an Alternative Small-Sample Degrees-of-Freedom Method

The Relation Between Aggression and the Living Group Climate in a Forensic Treatment Unit for Adolescents: A Pilot Study

scientific article published on June 2017

The Shape of Correlation Matrices

The analysis of multivariate longitudinal data: A review

scientific article

The analysis of multivariate longitudinal data: a review

scientific article published on 20 April 2012

The effect of correlation structure on treatment contrasts estimated from incomplete clinical trial data with likelihood-based repeated measures compared with last observation carried forward ANOVA.

scientific article

The gradient function as an exploratory goodness-of-fit assessment of the random-effects distribution in mixed models

scientific article published on 31 January 2013

The impact of missing data on clinical trials: a re-analysis of a placebo controlled trial of Hypericum perforatum (St Johns wort) and sertraline in major depressive disorder

scientific article

The meta-analytic framework for the evaluation of surrogate endpoints in clinical trials

The nature of sensitivity in monotone missing not at random models

article

The prevention and treatment of missing data in clinical trials

scientific article

The use of health care services and psychotropic medication in a community sample of 9-year-old schoolchildren with ADHD.

scientific article published on 16 July 2007

The use of score tests for inference on variance components

scientific article published in June 2003

The validation of surrogate end points by using data from randomized clinical trials: a case-study in advanced colorectal cancer

Thyroid Cancer Incidence around the Belgian Nuclear Sites, 2000-2014.

scientific article published on 31 August 2017

Thyroid cancer incidence near nuclear sites in Belgium: An ecological study at small geographical level

scientific article published on 10 December 2019

Titrating Theileria parva: single stocks against combination of stocks

scientific article

To adjust or not to adjust for baseline when analyzing repeated binary responses? The case of complete data when treatment comparison at study end is of interest

scientific article published on 10 April 2015

Type I and Type II error under random-effects misspecification in generalized linear mixed models

scientific article published on 9 April 2007

Type I error rates from likelihood-based repeated measures analyses of incomplete longitudinal data

article

Type-specific orthostatic hemodynamic response of hypertensive diseases in pregnancy

scientific article

Use of fractional polynomials for dose-response modelling and quantitative risk assessment in developmental toxicity studies

article

Using longitudinal data from a clinical trial in depression to assess the reliability of its outcome scales

scientific article

Validation of Surrogate Endpoints in Multiple Randomized Clinical Trials with Discrete Outcomes

Validation of a longitudinally measured surrogate marker for a time-to-event endpoint

Validation of surrogate end points in multiple randomized clinical trials with failure time end points

Validation of surrogate markers in multiple randomized clinical trials with repeated measurements: canonical correlation approach

scientific article published in December 2004

Venous Pulse Transit Time in Normal Pregnancy and Preeclampsia ⬇️

scientific article published on February 28, 2012

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