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List of works by Thomas Efferth

2'-O-Galloylhyperin Isolated From Pyrola incarnata Fisch. Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo

scientific article published on 27 June 2018

2'O-galloylhyperin attenuates LPS-induced acute lung injury via up-regulation antioxidation and inhibition of inflammatory responses in vivo

scientific article published on 06 March 2019

2α-Hydroxyalantolactone from Pulicaria undulata: activity against multidrug-resistant tumor cells and modes of action

scientific article published on 17 November 2020

5-Azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs.

scientific article published in May 2001

8,8-bis-(Dihydroconiferyl)-diferulate displayed impressive cytotoxicity towards a panel of human and animal cancer cells

scientific article published on 20 April 2020

A Five-year Survey of Cancer Prevalence in Sudan

scientific article published on January 2016

A Machine Learning-Based Prediction Platform for P-Glycoprotein Modulators and Its Validation by Molecular Docking

scientific article published on 21 October 2019

A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer

scientific article

A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care

scientific article

A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death

scientific article published on 19 March 2018

A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo.

scientific article published on 15 November 2006

A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner

scientific article published on 11 March 2010

A phenolic ester from Aglaia loheri leaves reveals cytotoxicity towards sensitive and multidrug-resistant cancer cells.

scientific article

A promising fusion: Traditional Chinese medicine and probiotics in the quest to overcome osteoporosis

scientific article published on 6 March 2025

A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin

scientific article published on 3 May 2012

A selective inhibitor of the Polo-box domain of Polo-like kinase 1 identified by virtual screening

scientific article published on 31 October 2018

A survey of chinese medicinal herbal treatment for chemotherapy-induced oral mucositis.

scientific article published on 28 October 2013

ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia

scientific article published in July 2006

AMG900 as novel inhibitor of the translationally controlled tumor protein

scientific article published on 28 November 2020

Abstract 1993: Fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells

article published in 2012

Abstract 3805: Artesunate reduces tumor growth in sunitinb-resistant renal cell carcinoma cells

scholarly article

Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin

scientific article published on 24 May 2018

Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel

scientific article

Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells.

scientific article published on 30 April 2010

Activity investigation of pinostrobin towards herpes simplex virus-1 as determined by atomic force microscopy.

scientific article published on 23 August 2010

Activity of Artemisia annua and artemisinin derivatives, in prostate carcinoma

scientific article published on 10 November 2015

Activity of Cordycepin From <i>Cordyceps sinensis</i> Against Drug-Resistant Tumor Cells as Determined by Gene Expression and Drug Sensitivity Profiling

scientific article published in 2021

Activity of ascaridol from the anthelmintic herb Chenopodium anthelminticum L. against sensitive and multidrug-resistant tumor cells.

scientific article

Activity of drugs from traditional Chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells.

scientific article

Activity of novel plant extracts against medullary thyroid carcinoma cells

scientific article published on March 2004

Activity of the antiestrogenic cajanin stilbene acid towards breast cancer

scientific article published on 22 July 2015

Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking

scientific article

Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking

Activity of three cytotoxic isoflavonoids from Erythrina excelsa and Erythrina senegalensis (neobavaisoflavone, sigmoidin H and isoneorautenol) toward multi-factorial drug resistant cancer cells

scientific article

Activity-guided isolation of scopoletin and isoscopoletin, the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells, from Artemisia argyi

scientific article published on July 2006

Acupuncture and herbal medicine for cancer patients 2014.

scientific article published on 28 August 2014

Acupuncture and herbal medicine for cancer patients.

scientific article

Adaptogens in chemobrain (Part I): Plant extracts attenuate cancer chemotherapy-induced cognitive impairment - Transcriptome-wide microarray profiles of neuroglia cells

scientific article published on 19 October 2018

Adaptogens in chemobrain (Part II): Effect of plant extracts on chemotherapy-induced cytotoxicity in neuroglia cells

scientific article published on 06 November 2018

Adaptogens in chemobrain (Part III): Antitoxic effects of plant extracts towards cancer chemotherapy-induced toxicity - transcriptome-wide microarray analysis of neuroglia cells

scientific article published on 09 November 2018

Adenosine triphosphate-binding cassette transporter genes in ageing and age-related diseases.

scientific article

Advances in antitumor activity and mechanism of natural steroidal saponins: A review of advances, challenges, and future prospects

scholarly article

African flora has the potential to fight multidrug resistance of cancer

scientific article published on 15 April 2015

Agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis

scientific article published on 05 December 2018

Alkamides from Echinacea angustifolia Interact with P-glycoprotein of primary brain capillary endothelial cells isolated from porcine brain blood vessels

scientific article

Aloe-emodin as drug candidate for cancer therapy

scientific article published on 3 April 2018

An effective negative pressure cavitation-microwave assisted extraction for determination of phenolic compounds in P. calliantha H. Andr

scientific article

Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia.

scientific article

Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8'- and 7,1'-linked metabolites from the Chinese liana Ancistrocladus tectorius.

scientific article published on 16 September 2016

Ancistrocyclinones A and B, unprecedented pentacyclic N,C-coupled naphthylisoquinoline alkaloids, from the Chinese liana Ancistrocladus tectorius.

scientific article published on 14 February 2018

Ancistrolikokine I and further 5,8'-coupled naphthylisoquinoline alkaloids from the Congolese liana Ancistrocladus likoko and their cytotoxic activities against drug-sensitive and multidrug resistant human leukemia cells

scientific article published on 22 June 2018

Animal plant warfare and secondary metabolite evolution

scientific article

Answer to the comment of Hai Lu et al. regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report and review of the literature. Arch Toxicol (2016)".

scientific article

Anti-Fas/Apo-1 Monoclonal Antibody CH-11 Depletes Glutathione and Kills Multidrug-Resistant Human Leukemic Cells

scientific article published on 01 January 1996

Anti-Infective and Antiproliferative Potential of African Medicinal Plants ⬇️

scientific article published on June 21, 2012

Anti-Inflammatory and Anti-Cancer Activity of Boswellic Acids from Frankincense (Boswellia serrata Roxb. et Colebr, B. carterii Birdw.)

Anti-Proliferative and Apoptosis-Inducing Effect of Theabrownin against Non-small Cell Lung Adenocarcinoma A549 Cells.

scientific article published on 02 December 2016

Anti-cancer natural product library from traditional chinese medicine

scientific article

Anti-infectious bronchitis virus (IBV) activity of 1,8-cineole: effect on nucleocapsid (N) protein

scientific article published on December 2010

Anti-inflammatory Effects of Herbal Preparations STW5 and STW5-II in Cytokine-Challenged Normal Human Colon Cells

scientific article published on 26 October 2016

Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities

scientific article published on 04 February 2020

Anti-leukemia activity of semi-synthetic phenolic derivatives from Polygonum limbatum Meisn

scientific article published on 24 June 2015

Anti-poliovirus activity of Nerium oleander aqueous extract

scientific article published on 25 March 2019

Antiangiogenic activity and pharmacogenomics of medicinal plants from traditional korean medicine.

scientific article published on 22 July 2013

Antibacterial activities and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes

scientific article published on 27 June 2016

Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components.

scientific article

Antibacterial activity and cytotoxicity of selected Egyptian medicinal plants

scientific article published on 4 November 2011

Antibody-directed therapy of multidrug-resistant tumor cells

scientific article published on January 1, 1992

Anticancer activities of six selected natural compounds of some Cameroonian medicinal plants

scientific article

Anticancer activity of cryptotanshinone on acute lymphoblastic leukemia cells.

scientific article

Antileukemic ancistrobenomine B and related 5,1'-coupled naphthylisoquinoline alkaloids from the Chinese liana Ancistrocladus tectorius.

scientific article

Antimicrobial activity and cytotoxicity towards cancer cells of Melaleuca alternifolia (tea tree) oil

article by Xia Liu et al published 25 March 2009 in European Food Research and Technology

Antimicrobial activity of clove and rosemary essential oils alone and in combination

scientific article published in October 2007

Antimicrobial and Antioxidant Activities of Natural Compounds.

scientific article

Antioxidant activities and xanthine oxidase inhibitory effects of extracts and main polyphenolic compounds obtained from Geranium sibiricum L.

scientific article published in April 2010

Antioxidant properties, superoxide dismutase and glutathione reductase activities in HepG2 cells with a fungal endophyte producing apigenin from pigeon pea [Cajanus cajan (L.) Millsp.]

Antiproliferative Properties of a Few Auranofin-Related Gold(I) and Silver(I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System

scientific article published on 28 September 2020

Antiproliferative activity against leukemia cells of sesquiterpene lactones from the Turkish endemic plant Centaurea drabifolia subsp. detonsa.

scientific article

Antiproliferative and erythroid differentiation of piperazine and triphenyl derivatives against k-562 human chronic myelogenous leukemia

scientific article published in August 2013

Antischistosomal activity of artemisinin derivatives in vivo and in patients

scientific article

Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study

scientific article published on 30 May 2019

Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses.

scientific article published on 8 December 2001

Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV).

scientific article published on 10 August 2006

Apoptosis and resistance to daunorubicin in human leukemic cells.

scientific article published in July 1997

Application of integrative cloud point extraction and concentration for the analysis of polyphenols and alkaloids in mulberry leaves

scientific article published on 10 February 2019

Aptamers as a novel tool for diagnostics and therapy.

scientific article published on February 2015

Aqueous enzymatic process assisted by microwave extraction of oil from yellow horn (Xanthoceras sorbifolia Bunge.) seed kernels and its quality evaluation.

scientific article

Artemisia herba-alba essential oil from Buseirah (South Jordan): Chemical characterization and assessment of safe antifungal and anti-inflammatory doses.

scientific article

Artemisinin Derivatives Target Topoisomerase 1 and Cause DNA Damage in Silico and in Vitro

scientific article published on 9 October 2017

Artemisinin derivative FO-ARS-123 as a novel VEGFR2 inhibitor suppresses angiogenesis, cell migration, and invasion

scientific article published in 2022

Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells.

scientific article published on 18 August 2015

Artemisinin und seine Derivate – eine neue Option für die Krebstherapie?

Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction

scientific article published on 09 December 2020

Artesunate Inhibits Growth of Sunitinib-Resistant Renal Cell Carcinoma Cells through Cell Cycle Arrest and Induction of Ferroptosis

scientific article published on 27 October 2020

Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production

scientific article

Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation

scientific article published in May 2008

Artesunate derived from traditional Chinese medicine induces DNA damage and repair.

scientific article

Artesunate in the treatment of metastatic uveal melanoma--first experiences

scientific article published on December 2005

Artesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cells

scientific article

Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells

scientific article published on 13 October 2011

Aspidin PB, a phloroglucinol derivative, induces apoptosis in human hepatocarcinoma HepG2 cells by modulating PI3K/Akt/GSK3β pathway.

scientific article published on 21 November 2012

Bacteria-Derived Compatible Solutes Ectoine and 5α-Hydroxyectoine Act as Intestinal Barrier Stabilizers to Ameliorate Experimental Inflammatory Bowel Disease

scientific article published on 28 May 2015

Berberine inhibits cell growth and mediates caspase-independent cell death in human pancreatic cancer cells.

scientific article

Best practice in research - Overcoming common challenges in phytopharmacological research

scientific article published on 14 September 2019

Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR).

scientific article published on 15 May 2018

Beyond malaria: The inhibition of viruses by artemisinin-type compounds

scientific article published on 3 January 2018

Bioinformatic and experimental fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells.

scientific article published on 6 February 2012

Biopiracy of medicinal plants: Finding fair solutions for the use of natural resources

article

Biopiracy of natural products and good bioprospecting practice

scientific article published on 9 January 2016

Biopiracy versus One-World Medicine-From colonial relicts to global collaborative concepts

scientific article published on 11 June 2018

Biotechnology Applications of Plant Callus Cultures

scholarly article

Bisphenolic compounds alter gene expression in MCF-7 cells through interaction with estrogen receptor α

scientific article published on 06 May 2020

Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells

scientific article

Breaking the spores of the fungus Ganoderma lucidum by supercritical CO2

Broad-spectrum Cross-resistance to Anticancer Drugs Mediated by Epidermal Growth Factor Receptor

scientific article published on 01 July 2019

Broken heart, tako-tsubo or stress cardiomyopathy? Metaphors, meanings and their medical impact

scientific article published on 22 December 2016

COMMENTARY. Biochemistry and Gene regulation of YY1

article

Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats

scientific article published on 04 July 2019

Cajaninstilbene acid (CSA) exerts cytoprotective effects against oxidative stress through the Nrf2-dependent antioxidant pathway

scientific article published on 25 March 2013

Cajanol inhibits the growth of Escherichia coli and Staphylococcus aureus by acting on membrane and DNA damage

scientific article published on 27 August 2010

Cajanol, a novel anticancer agent from Pigeonpea [Cajanus cajan (L.) Millsp.] roots, induces apoptosis in human breast cancer cells through a ROS-mediated mitochondrial pathway.

scientific article published on 16 July 2010

Cameroonian Medicinal Plants: Pharmacology and Derived Natural Products ⬇️

scientific article published on October 25, 2010

Can eastern wisdom resolve western epidemics? Traditional Chinese medicine therapies and the opioid crisis

scientific article published on 19 March 2021

Can heat and cold be parameterized? Clinical data of a preliminary study

scientific article

Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy?

scientific article published on 31 July 2013

Cancer Therapy with Natural Products and Medicinal Plants ⬇️

scientific article published on July 27, 2010

Cancer combination therapies with artemisinin-type drugs

scientific article

Cancer combination therapy of the sesquiterpenoid artesunate and the selective EGFR-tyrosine kinase inhibitor erlotinib

scientific article published on 10 November 2017

Cardenolides: Insights from chemical structure and pharmacological utility

scientific article published on 21 December 2018

Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish

scientific article published on 13 January 2020

Catalytic synthesis of α-oxoketene S,S-acetals in a wet ionic liquid [Bmim]Cl/H₂O homogeneous system.

scientific article published on 27 May 2011

Catalytic transesterification of Pistacia chinensis seed oil using HPW immobilized on magnetic composite graphene oxide/cellulose microspheres

scholarly article published in November 2018

Cell Harvesting Methods Affect Cellular Integrity of Adherent Cells During Apoptosis Detection

scientific article published on 01 December 2018

Cell cycle arrest and induction of apoptosis by cajanin stilbene acid from Cajanus cajan in breast cancer cells

scientific article published on 11 March 2015

Characterization of five fungal endophytes producing Cajaninstilbene acid isolated from pigeon pea [Cajanus cajan (L.) Millsp]

scientific article

Chemical Composition and antiproliferative activity of essential oil from the leaves of a medicinal herb, Levisticum officinale, against UMSCC1 head and neck squamous carcinoma cells.

scientific article published on January 2011

Chemical composition and biological activities of Artemisia judaica essential oil from southern desert of Jordan

scientific article

Chemical composition and biological activity of the essential oil obtained from Bupleurum marginatum (Apiaceae)

article

Chemical composition and biological activity of the essential oil obtained from Bupleurum marginatum (Apiaceae).

scientific article

Chemical-Biology of Natural Products from Medicinal Plants for Cancer Therapy

article

Chemistry and pharmacology of neglected helminthic diseases

scientific article published on January 2011

Chemometric and Transcriptomic Profiling, Microtubule Disruption and Cell Death Induction by Secalonic Acid in Tumor Cells

scientific article published on 15 July 2020

Chemopreventive Property of Sencha Tea Extracts towards Sensitive and Multidrug-Resistant Leukemia and Multiple Myeloma Cells

scientific article published on 04 July 2020

Chemoresistance and chemosensitization in cholangiocarcinoma.

scientific article

Chemotherapeutic efficacy of curcumin and resveratrol against cancer: Chemoprevention, chemoprotection, drug synergism and clinical pharmacokinetics

scientific article published on 02 November 2020

Chemotherapy-induced resistance by ATP-binding cassette transporter genes.

scientific article published on 6 June 2007

Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-ĸB pathway in chondrocytes.

scientific article published in May 2019

Collateral Sensitivity of Parthenolide via NF-κB and HIF-α Inhibition and Epigenetic Changes in Drug-Resistant Cancer Cell Lines.

scientific article published on 21 May 2019

Collateral sensitivity of drug-resistant ABCB5- and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expression

scientific article published on 14 March 2019

Collateral sensitivity of natural products in drug-resistant cancer cells

scientific article published on 29 January 2019

Combination treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774.

scientific article published on May 2004

Combination treatment of malignant B cells using the anti-CD20 antibody rituximab and the anti-malarial artesunate

scientific article

Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences

scientific article published on 29 August 2019

Comparative M-FISH and CGH analyses in sensitive and drug-resistant human T-cell acute leukemia cell lines.

scientific article published in January 2002

Comparison between tumors in plants and human beings: Mechanisms of tumor development and therapy with secondary plant metabolites

scientific article published on 03 September 2019

Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy

scientific article published on January 2011

Comprehensive Overview on Multiple Strategies Fighting COVID-19

scientific article published on 11 August 2020

Contributions from emerging transcriptomics technologies and computational strategies for drug discovery.

scientific article published on 16 March 2014

Coptis chinensis Franch. exhibits neuroprotective properties against oxidative stress in human neuroblastoma cells.

scientific article

Coronaviral Ion Channels as Target for Chinese Herbal Medicine

article

Coronavirus Inhibitors Targeting nsp16

scientific article published on 18 January 2023

Correction: Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1

Correlation of cultivation time of Panax ginseng with metabolic profiles of nine ginsenosides and mRNA expression of genes encoding major biosynthetic enzymes

article

Correlations between natural resistance to doxorubicin, proliferative activity, and expression of P-glycoprotein 170 in human kidney tumor cell lines

scientific article published in January 1990

Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 macrophages

scientific article published on 29 March 2020

Cryptotanshinone deregulates unfolded protein response and eukaryotic initiation factor signaling in acute lymphoblastic leukemia cells.

scientific article published on 04 January 2016

Curcumin downregulates expression of opioid-related nociceptin receptor gene (OPRL1) in isolated neuroglia cells

scientific article published on 20 September 2018

Cytochrome P450 reaction phenotyping and inhibition and induction studies of pinostrobin in human liver microsomes and hepatocytes.

scientific article

Cytotoxic Benzophenanthridine and Furoquinoline Alkaloids from Zanthoxylum buesgenii (Rutaceae).

scientific article

Cytotoxic Bufadienolides from the Leaves of Melianthus major

scientific article published on 14 July 2020

Cytotoxic activity of curcumin towards CCRF-CEM leukemia cells and its effect on DNA damage

scientific article published on 17 December 2009

Cytotoxic activity of isoliquiritigenin towards CCRF-CEM leukemia cells and its effect on DNA damage.

scientific article published on 16 March 2009

Cytotoxic activity of medicinal plants of the Kakamega County (Kenya) against drug-sensitive and multidrug-resistant cancer cells

scientific article published on 5 January 2018

Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin

scientific article published on 9 August 2011

Cytotoxic and new tetralone derivatives from Berchemia floribunda (Wall.) Brongn. ⬇️

scientific article published on June 2006

Cytotoxic benzylbenzofuran derivatives from Dorstenia kameruniana

scientific article published on 30 April 2018

Cytotoxic bufadienolides from the leaves of a medicinal plant Melianthus comosus collected in South Africa

scientific article published on 15 July 2020

Cytotoxic compounds from the fruits of Uapaca togoensis towards multifactorial drug-resistant cancer cells

scientific article

Cytotoxic flavonoids and isoflavonoids from Erythrina sigmoidea towards multi-factorial drug resistant cancer cells.

scientific article

Cytotoxic flavonoids from two Lonchocarpus species

scientific article published on 16 April 2018

Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells

scientific article published on 27 November 2020

Cytotoxicity and Modes of Action of the Methanol Extracts of Six Cameroonian Medicinal Plants against Multidrug-Resistant Tumor Cells

scientific article published on 23 September 2013

Cytotoxicity and antimitotic activity of Rhinella schneideri and Rhinella marina venoms

scientific article published on 29 June 2019

Cytotoxicity and apoptosis induction by Fumaria officinalis extracts in leukemia and multiple myeloma cell lines

scientific article published on 09 October 2020

Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand

scientific article

Cytotoxicity and mode of action of a naturally occurring naphthoquinone, 2-acetyl-7-methoxynaphtho[2,3-b]furan-4,9-quinone towards multi-factorial drug-resistant cancer cells

scientific article

Cytotoxicity and mode of action of four naturally occuring flavonoids from the genus Dorstenia: gancaonin Q, 4-hydroxylonchocarpin, 6-prenylapigenin, and 6,8-diprenyleriodictyol.

scientific article published on 28 July 2011

Cytotoxicity and modes of action of 4'-hydroxy-2',6'-dimethoxychalcone and other flavonoids toward drug-sensitive and multidrug-resistant cancer cell lines

scientific article

Cytotoxicity and modes of action of five Cameroonian medicinal plants against multi-factorial drug resistance of tumor cells

scientific article published on 28 February 2014

Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense.

scientific article published on July 2013

Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol

scientific article

Cytotoxicity and modes of action of three naturally occurring xanthones (8-hydroxycudraxanthone G, morusignin I and cudraxanthone I) against sensitive and multidrug-resistant cancer cell lines

scientific article published on 24 September 2013

Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa.

scientific article published on 6 December 2007

Cytotoxicity and pharmacogenomics of medicinal plants from traditional korean medicine

scientific article published on 11 July 2013

Cytotoxicity of 15 Cameroonian medicinal plants against drug sensitive and multi-drug resistant cancer cells

scientific article published on 05 April 2016

Cytotoxicity of 18 Cameroonian medicinal plants against drug sensitive and multi-factorial drug resistant cancer cells

scientific article published on 27 April 2018

Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells

scientific article published on 9 July 2015

Cytotoxicity of 40 Egyptian plant extracts targeting mechanisms of drug-resistant cancer cells

scientific article published on 26 November 2018

Cytotoxicity of 91 Kenyan indigenous medicinal plants towards human CCRF-CEM leukemia cells

scientific article published on 22 December 2015

Cytotoxicity of Crude Extract and Isolated Constituents of the Dichrostachys cinerea Bark towards Multifactorial Drug-Resistant Cancer Cells

scientific article published on 08 July 2019

Cytotoxicity of Elaoephorbia drupifera and other Cameroonian medicinal plants against drug sensitive and multidrug resistant cancer cells.

scientific article

Cytotoxicity of Endoperoxides from the Caribbean Sponge Plakortis halichondrioides towards Sensitive and Multidrug-Resistant Leukemia Cells: Acids vs. Esters Activity Evaluation.

scientific article published on 03 March 2017

Cytotoxicity of Salvia miltiorrhiza Against Multidrug-Resistant Cancer Cells.

scientific article published on 24 May 2016

Cytotoxicity of South-African medicinal plants towards sensitive and multidrug-resistant cancer cells.

scientific article published on 04 April 2016

Cytotoxicity of Thymus vulgaris essential oil towards human oral cavity squamous cell carcinoma.

scientific article published on January 2011

Cytotoxicity of a naturally occuring spirostanol saponin, progenin III, towards a broad range of cancer cell lines by induction of apoptosis, autophagy and necroptosis

scientific article published on 23 May 2020

Cytotoxicity of a naturally occurring furoquinoline alkaloid and four acridone alkaloids towards multi-factorial drug-resistant cancer cells

scientific article published on 17 July 2015

Cytotoxicity of abietane diterpenoids from Salvia multicaulis towards multidrug-resistant cancer cells

scientific article published on 13 August 2018

Cytotoxicity of an unprecedented brominated oleanolide and a new furoceramide from the Cameroonian spice, Echinops giganteus.

scientific article published on 5 January 2016

Cytotoxicity of anthraquinones from the roots of Pentas schimperi towards multi-factorial drug-resistant cancer cells

scientific article

Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells

scientific article published on 08 October 2020

Cytotoxicity of artesunic acid homo- and heterodimer molecules toward sensitive and multidrug-resistant CCRF-CEM leukemia cells

scientific article

Cytotoxicity of botanicals and isolated phytochemicals from Araliopsis soyauxii Engl. (Rutaceae) towards a panel of human cancer cells

scientific article published on 06 November 2020

Cytotoxicity of cardiotonic steroids in sensitive and multidrug-resistant leukemia cells and the link with Na(+)/K(+)-ATPase

scientific article

Cytotoxicity of compounds from Xylopia aethiopica towards multi-factorial drug-resistant cancer cells

scientific article published on 31 October 2015

Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells

scientific article published on 02 May 2019

Cytotoxicity of epunctanone and four other phytochemicals isolated from the medicinal plants Garcinia epunctata and Ptycholobium contortum towards multi-factorial drug resistant cancer cells

scientific article published on 18 December 2017

Cytotoxicity of fagaramide derivative and canthin-6-one from Zanthoxylum (Rutaceae) species against multidrug resistant leukemia cells

scientific article published on 21 March 2019

Cytotoxicity of four Aframomum species (A. arundinaceum, A. alboviolaceum, A. kayserianum and A. polyanthum) towards multi-factorial drug resistant cancer cell lines

scientific article

Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer

scientific article published on 30 January 2019

Cytotoxicity of medicinal plants of the West-Canadian Gwich׳in Native Americans towards sensitive and multidrug-resistant cancer cells

scientific article

Cytotoxicity of methanol extracts of 10 Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines

scientific article

Cytotoxicity of methanol extracts of Annona muricata, Passiflora edulis and nine other Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines

scientific article

Cytotoxicity of natural products and derivatives toward MCF-7 cell monolayers and cancer stem-like mammospheres.

scientific article published on 21 February 2015

Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation

Cytotoxicity of novel sulfanilamides towards sensitive and multidrug-resistant leukemia cells.

scientific article published on January 2014

Cytotoxicity of selected Cameroonian medicinal plants and Nauclea pobeguinii towards multi-factorial drug-resistant cancer cells

scientific article published on 4 September 2015

Cytotoxicity of sesquiterpene alkaloids from Nuphar plants toward sensitive and drug-resistant cell lines

article

Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells

scientific article published on 27 April 2016

Cytotoxicity of some Cameroonian spices and selected medicinal plant extracts

scientific article published on February 2011

Cytotoxicity of the Sesquiterpene Lactones Neoambrosin and Damsin from Ambrosia maritima Against Multidrug-Resistant Cancer Cells

scientific article

Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by pharmacogenomics and molecular docking

scientific article published on 28 August 2014

Cytotoxicity of the crude extract and constituents of the bark of Fagara tessmannii towards multi-factorial drug resistant cancer cells

scientific article published on 29 January 2019

Cytotoxicity of the indole alkaloid reserpine from Rauwolfia serpentina against drug-resistant tumor cells

scientific article

Cytotoxicity of three naturally occurring flavonoid derived compounds (artocarpesin, cycloartocarpesin and isobavachalcone) towards multi-factorial drug-resistant cancer cells

scientific article published on 11 August 2015

Cytotoxicity of two naturally occurring flavonoids (dorsmanin F and poinsettifolin B) towards multi-factorial drug-resistant cancer cells

scientific article

Cytotoxicity of ungeremine towards multi-factorial drug resistant cancer cells and induction of apoptosis, ferroptosis, necroptosis and autophagy

scientific article published on 15 January 2019

Cytotoxicity, anti-angiogenic, apoptotic effects and transcript profiling of a naturally occurring naphthyl butenone, guieranone A.

scientific article published on 20 June 2012

Cytotoxicity, mode of action and antibacterial activities of selected Saudi Arabian medicinal plants

scientific article

DNA Polymorphisms Affecting Chemosensitivity Toward Drugs

Daedalea gibbosa substances inhibit LPS-induced expression of iNOS by suppression of NF-kappaB and MAPK activities in RAW 264.7 macrophage cells ⬇️

scientific article

Daphne striata Tratt. and D. mezereum L.: a study of anti-proliferative activity towards human cancer cells and antioxidant properties.

scientific article published on 12 February 2018

Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties

scientific article published on 12 July 2010

Detection of P-glycoprotein in human leukemias using monoclonal antibodies

scientific article

Detection of drug resistance in human ovarian carcinoma

scientific article

Detection of the multidrug resistant phenotype in human tumours by monoclonal antibodies and the streptavidin-biotinylated phycoerythrin complex method

scientific article published on 01 April 1989

Determination and quantification of astragalosides in Radix Astragali and its medicinal products using LC-MS.

scientific article published in February 2009

Determination of paclitaxel and its analogues in the needles of Taxus species by using negative pressure cavitation extraction followed by HPLC-MS-MS.

scientific article published in November 2009

Determination of paclitaxel and other six taxoids in Taxus species by high-performance liquid chromatography-tandem mass spectrometry.

scientific article published on 19 October 2008

Determination of vitexin and isovitexin in pigeonpea using ultrasonic extraction followed by LC-MS.

scientific article

Development of artemisinin resistance in malaria therapy

scientific article published on 14 May 2019

Development of drug resistance in Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Treatment of human African trypanosomiasis with natural products (Review).

scientific article published on October 2008

Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells

scientific article

Diabetes and Metabolism Disorders Medicinal Plants: A Glance at the Past and a Look to the Future 2018

article

Diagnosis and objective pain assessment of traditional Chinese medicine may be useful to demonstrate specific effects of acupuncture in low back pain: A prospective, randomized, controlled and single blinded pre-study

scientific article

Diagnosis and therapy of oral squamous cell carcinoma.

scientific article published on March 2007

Didactics of Molecular Ecology

Differential interactions of the broad spectrum drugs artemisinin, dihydroartemisinin and artesunate with serum albumin

scientific article published on 16 May 2013

Differentially Tolerized Mouse Antigen Presenting Cells Share a Common miRNA Signature Including Enhanced mmu-miR-223-3p Expression Which Is Sufficient to Imprint a Protolerogenic State

scholarly article by Matthias Bros et al published 2018 in Frontiers in Pharmacology

Dihydroquercetin (DHQ) induced HO-1 and NQO1 expression against oxidative stress through the Nrf2-dependent antioxidant pathway.

scientific article published on 5 March 2013

Dioncophyllines C2, D2, and F and Related Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ileboensis with Potent Activities against Plasmodium falciparum and against Multiple Myeloma and Leukemia Cell Lines.

scientific article published on 25 January 2017

Dis-organizing centrosomal clusters: specific cancer therapy for a generic spread?

scientific article

Diversity of Pharmacological Properties in Chinese and European Medicinal Plants: Cytotoxicity, Antiviral and Antitrypanosomal Screening of 82 Herbal Drugs

article

Drug Repurposing of the Anthelmintic Niclosamide to Treat Multidrug-Resistant Leukemia.

scientific article published on 10 March 2017

Drug Resistance in Plasmodium: Natural Products in the Fight Against Malaria

scientific article published in February 2009

Drug targets and resistance mechanisms in multiple myeloma

scholarly article published on 20 May 2018

Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway.

scientific article

EGFR but not PDGFR-beta expression correlates to the antiproliferative effect of growth factor withdrawal in glioblastoma multiforme cell lines.

scientific article published on May 2003

Editorial [Hot Topic: SMALL MOLECULES OF NATURAL ORIGIN FOR CANCER THERAPY AND CHEMOPREVENTION Part I: Pharmacognosy and Molecular Pharmacology of Small Molecules of Natural Origin for Cancer Therapy and Chemoprevention (Guest Editor: Thomas Efferth

scientific article published on 01 March 2006

Editorial [Hot Topic: Small Molecules of Natural Origin for Cancer Therapy and Chemoprevention Part II: Pharmacogenomics and Biotechnological Applications of Small Molecules of Natural Origin for Cancer Therapy and Chemoprevention]

article published in 2006

Editorial [Hot Topic:Molecular Mechanisms of and Clinical Evidence for Interactions Between Natural Products and Drugs (Guest Editor: Thomas Efferth)]

article

Editorial: Chemoprevention of cancer by natural products

scientific article published on 27 May 2019

Effect of ABC transporter expression and mutational status on survival rates of cancer patients

scientific article published on 12 September 2020

Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system.

scientific article published on 10 August 2005

Effect of artemisinins and other endoperoxides on nitric oxide-related signaling pathway in RAW 264.7 mouse macrophage cells

scientific article

Effect of artesunate on immune cells in ret-transgenic mouse melanoma model

scientific article

Effect of cantharidin, cephalotaxine and homoharringtonine on "in vitro" models of hepatitis B virus (HBV) and bovine viral diarrhoea virus (BVDV) replication

scientific article published on 26 April 2007

Effects of Scrophularia ningpoensis Hemsl. on Inhibition of Proliferation, Apoptosis Induction and NF-κB Signaling of Immortalized and Cancer Cell Lines

scientific article published on 14 February 2012

Effects of acupuncture on leucopenia, neutropenia, NK, and B cells in cancer patients: a randomized pilot study

scientific article

Effects of anti-inflammatory and adaptogenic herbal extracts on gene expression of eicosanoids signaling pathways in isolated brain cells

scientific article published on 10 March 2019

Effects of artesunate on cytokinesis and G₂/M cell cycle progression of tumour cells and budding yeast.

scientific article

Effects of qigong on performance-related anxiety and physiological stress functions in transverse flute music schoolchildren: a feasibility study

scientific article

Efficient Lewis acid ionic liquid-catalyzed synthesis of the key intermediate of coenzyme Q10 under microwave irradiation

scientific article published on 22 December 2010

Efficient extraction and preparative separation of four main isoflavonoids from Dalbergia odorifera T. Chen leaves by deep eutectic solvents-based negative pressure cavitation extraction followed by macroporous resin column chromatography.

scientific article published on 3 August 2016

Efficient production of isoflavonoids by Astragalus membranaceus hairy root cultures and evaluation of antioxidant activities of extracts

scientific article published on 17 December 2014

Elatumic acid: a new ursolic acid congener from Omphalocarpum elatum Miers (Sapotaceae).

scientific article published on July 2014

Enhanced extraction of astragalosides from Radix Astragali by negative pressure cavitation-accelerated enzyme pretreatment.

scientific article published on 26 May 2010

Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity

Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron

scientific article

Enzymatic water extraction of taxifolin from wood sawdust of Larix gmelini (Rupr.) Rupr. and evaluation of its antioxidant activity

Enzyme assisted extraction of luteolin and apigenin from pigeonpea [Cajanuscajan (L.) Millsp.] leaves.

scientific article published on 7 April 2008

Enzyme pretreatment and negative pressure cavitation extraction of genistein and apigenin from the roots of pigeon pea [Cajanus cajan (L.) Millsp.] and the evaluation of antioxidant activity

scholarly article in Industrial Crops and Products, vol. 37 no. 1, May 2012

Epimagnolin A, a tetrahydrofurofuranoid lignan from Magnolia fargesii, reverses ABCB1-mediated drug resistance

scientific article published on 20 June 2018

Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue.

scientific article published on January 2012

Ethnobotanical survey and cytotoxicity testing of plants of South-western Nigeria used to treat cancer, with isolation of cytotoxic constituents from Cajanus cajan Millsp. leaves

scientific article

Ethnopharmacology, phytochemistry, chemical ecology and invasion biology of Acanthus mollis L.

scientific article published on 14 November 2021

Ethylene increases accumulation of compatible solutes and decreases oxidative stress to improve plant tolerance to water stress in Arabidopsis

article

Euphosantianane A⁻D: Antiproliferative Premyrsinane Diterpenoids from the Endemic Egyptian Plant

article

Evaluating ancient Egyptian prescriptions today: Anti-inflammatory activity of Ziziphus spina-christi.

scientific article published on 02 February 2016

Evaluation of Long-Time Decoction-Detoxicated Hei-Shun-Pian (Processed Aconitum carmichaeli Debeaux Lateral Root With Peel) for Its Acute Toxicity and Therapeutic Effect on Mono-Iodoacetate Induced Osteoarthritis

scientific article published on 24 July 2020

Evaluation of drug transporters' significance for multidrug resistance in head and neck squamous cell carcinoma

scientific article published on 24 August 2010

Evidence-based Chinese medicine for cancer therapy.

scientific article

Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases

scientific article published on 25 October 2020

Exploring Natural Product-Based Cancer Therapeutics Derived from Egyptian Flora

scientific article published on 25 November 2020

Expression Profiling of ABC-Transporters in Childhood AML Reveals ABCA3 as a Potential Cause of Drug Resistance. ⬇️

scholarly article

Expression of apoptosis-related oncoproteins and modulation of apoptosis by caffeine in human leukemic cells

scientific article published in January 1995

Expression profile of genes in non-small cell lung carcinomas from long-term surviving patients

scientific article published on 01 June 2002

Expression profile of proteins involved in the xenotransplantability of non-small cell lung cancers into athymic nude mice

scientific article published on 01 February 2002

Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia

scientific article published on 01 August 2006

Extract of Caragana sinica as a potential therapeutic option for increasing alpha-secretase gene expression.

scientific article published on 14 August 2015

FISH studies on the telomeric regions of the T-cell acute lymphoblastic leukemia cell line CCRF-CEM.

scientific article published in January 2005

Factors determining sensitivity and resistance of tumor cells to arsenic trioxide

scientific article

Factors determining sensitivity or resistance of tumor cell lines towards artesunate.

scientific article

Fatal Liver and Bone Marrow Toxicity by Combination Treatment of Dichloroacetate and Artesunate in a Glioblastoma Multiforme Patient: Case Report and Review of the Literature

scientific article

Fighting cancer with red wine? Molecular mechanisms of resveratrol.

scientific article published on October 2009

Fighting mycobacterial infections by antibiotics, phytochemicals and vaccines

scientific article published on 09 September 2010

First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases

scientific article published in September 2010

First study of oral Artenimol-R in advanced cervical cancer: clinical benefit, tolerability and tumor markers.

scientific article

Free radical scavenging capability, antioxidant activity and chemical constituents of Pyrola incarnata Fisch. leaves

scholarly article in Industrial Crops and Products, vol. 49, August 2013

From Molecular Tumor Diagnostics to Individualized Treatment with Phytochemicals Derived from Chinese Herbs

article

From ancient herb to versatile, modern drug: Artemisia annua and artemisinin for cancer therapy

scientific article published on 27 February 2017

From traditional Chinese medicine to rational cancer therapy.

scientific article published on 17 July 2007

Furoquinolines and dihydrooxazole alkaloids with cytotoxic activity from the stem bark of Araliopsis soyauxii

scientific article published on 14 January 2019

GPR84 and TREM-1 signaling contribute to the pathogenesis of reflux esophagitis.

scientific article published on 24 November 2015

Gems from traditional north-African medicine: medicinal and aromatic plants from Sudan

scientific article published on 17 April 2012

Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells.

scientific article published on 22 April 2009

Genetic Mouse Models with Intestinal-Specific Tight Junction Deletion Resemble an Ulcerative Colitis Phenotype.

scientific article published on 27 May 2017

Genomic and transcriptomic profiling of resistant CEM/ADR-5000 and sensitive CCRF-CEM leukaemia cells for unravelling the full complexity of multi-factorial multidrug resistance

scientific article published on 8 November 2016

Genomic gain of the epidermal growth factor receptor harboring band 7p12 is part of a complex pattern of genomic imbalances in oral squamous cell carcinomas.

scientific article published in September 2004

Genomic imbalances in T-cell acute lymphoblastic leukemia cell lines.

scientific article published on October 2002

Genomic imbalances in drug-resistant T-cell acute lymphoblastic CEM leukemia cell lines.

scientific article published on July 2002

Genomic landscape analyses in cervical carcinoma and consequences for treatment

scientific article published on 06 November 2020

Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity

scientific article

Glucose-6-phosphate dehydrogenase (G6PD) deficiency-type Zurich: a splice site mutation as an uncommon mechanism producing enzyme deficiency.

scientific article published in October 2004

Glutathione-related enzymes contribute to resistance of tumor cells and low toxicity in normal organs to artesunate

scientific article

Glycyrrhizic acid nanoparticles inhibit LPS-induced inflammatory mediators in 264.7 mouse macrophages compared with unprocessed glycyrrhizic acid

scientific article published on 12 April 2013

Growth factors-based beneficial effects of platelet lysate on umbilical cord-derived stem cells and their synergistic use in osteoarthritis treatment

scientific article published on 14 October 2020

Growth inhibition of human acute lymphoblastic CCRF-CEM leukemia cells by medicinal plants of the West-Canadian Gwich’in Native Americans

scientific article published on 24 February 2012

Growth-dependent release of carbohydrate metabolism-related and antioxidant enzymes from Staphylococcus aureus strain 6 as determined by proteomic analysis.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Hepatoprotective and anti-inflammatory effects of total flavonoids of Qu Zhi Ke (peel of Citrus changshan-huyou) on non-alcoholic fatty liver disease in rats via modulation of NF-κB and MAPKs

scientific article published on 03 September 2019

Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature.

scientific article published on 12 August 2016

Herpes simplex virus: Drug resistance and new treatment options using natural products (Review).

scientific article published on September 2008

Heterocycles 44. Synthesis, characterization and anticancer activity of new thiazole ortho-hydroxychalcones

High rate of expression of multidrug resistance-associated P-glycoprotein in human endometrial carcinoma and normal endometrial tissue

scientific article

Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities

scientific article published on 29 July 2015

Hildebert Wagner Award Laureate announcement December 2015.

scientific article published in January 2016

Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines.

scientific article

Hormesis: Decoding Two Sides of the Same Coin

scientific article

Human ABCB1 confers cells resistance to cytotoxic guanidine alkaloids from Pterogyne nitens

scientific article

Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation.

scientific article published on 3 April 2011

Human cytomegalovirus: Drug resistance and new treatment options using natural products

scientific article published on 01 November 2008

Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma

scientific article published on 25 September 2020

Identification by high-throughput in silico screening of radio-protecting compounds targeting the DNA-binding domain of the tumor suppressor p53.

scientific article published on January 2013

Identification of NF-κB as Determinant of Posttraumatic Stress Disorder and Its Inhibition by the Chinese Herbal Remedy Free and Easy Wanderer.

scientific article published on 06 April 2017

Identification of Novel Rare ABCC1 Transporter Mutations in Tumor Biopsies of Cancer Patients

scientific article published on 26 January 2020

Identification of Phlogacantholide C as a Novel ADAM10 Enhancer from Traditional Chinese Medicinal Plants.

scientific article published on 5 December 2016

Identification of cellular and molecular factors determining the response of cancer cells to six ergot alkaloids.

scientific article

Identification of fatal outcome in a childhood nasopharyngeal carcinoma patient by protein expression profiling

scientific article published on 19 July 2018

Identification of gene expression profiles predicting tumor cell response to L-alanosine.

scientific article published in August 2003

Identification of inhibitors of the polo-box domain of polo-like kinase 1 from natural and semisynthetic compounds

scientific article published on 15 March 2019

Identification of metastasis-related genes by genomic and transcriptomic studies in murine melanoma

scientific article published on 21 December 2020

Identification of new P-glycoprotein inhibitors derived from cardiotonic steroids

scientific article

Identification of potential inhibitors targeting BRAF-V600E mutant melanoma cells

scientific article published on 21 July 2020

Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1.

scientific article published on 27 May 2016

Immunohistochemical Detection of P Glycoprotein, Glutathione S Transferase and DNATopoisomerase II in Human Tumors

scientific article published on 01 January 1992

Immunohistochemical detection of the multi-drug-resistance marker P-glycoprotein in uterine cervical carcinomas and normal cervical tissue

scientific article published in March 1992

Immunotoxicity of Therapeutic Antibodies and Nanoparticles

scientific article published on 01 January 2020

In Silico Analysis of Microarray-Based Gene Expression Profiles Predicts Tumor Cell Response to Withanolides

scientific article published on 22 May 2012

In Vitro Antioxidant and Cytotoxic Activities of 18 Plants from the Erkowit Region, Eastern Sudan

scientific article published on 16 February 2018

In Vitro Study of the Cytotoxic, Cytostatic, and Antigenotoxic Profile of Hemidesmus indicus (L.) R.Br. (Apocynaceae) Crude Drug Extract on T Lymphoblastic Cells.

scientific article published on 6 February 2018

In Vivo Cardiotoxicity Induced by Sodium Aescinate in Zebrafish Larvae

scientific article published on 23 February 2016

In silico drug discovery of major metabolites from spices as SARS-CoV-2 main protease inhibitors

scientific article published on 08 October 2020

In vitro antioxidant and antimicrobial activity of extracts from Morus alba L. leaves, stems and fruits.

scientific article published in January 2012

In vitro antioxidant properties, DNA damage protective activity, and xanthine oxidase inhibitory effect of cajaninstilbene acid, a stilbene compound derived from pigeon pea [Cajanus cajan (L.) Millsp.] leaves.

scientific article published on 3 December 2010

In vitro cytotoxicity and P-glycoprotein modulating effects of geranylated furocoumarins from Tetradium daniellii.

scientific article published on 8 November 2007

In vivo acute toxicity of detoxified Fuzi (lateral root of Aconitum carmichaeli) after a traditional detoxification process

Increased induction of apoptosis in mononuclear cells of a glucose-6-phosphate dehydrogenase deficient patient

scientific article published on 01 January 1995

Indeno[1,2,3-cd]pyrene and picene mediate actions via estrogen receptor α signaling pathway in in vitro cell systems, altering gene expression

scientific article published on 03 April 2020

Individualized Tumor Therapy: Biomarkers and Possibilities for Targeted Therapy with Natural Products

Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities.

scientific article

Induced multidrug resistance in murine leukemia L1210 and associated changes in a surface-membrane glycoprotein

scientific article published in January 1989

Induction of Apoptosis, Autophagy and Ferroptosis by Thymus vulgaris and Arctium lappa Extract in Leukemia and Multiple Myeloma Cell Lines

scientific article published on 29 October 2020

Induction of apoptosis, depletion of glutathione, and DNA damage by extracorporeal photochemotherapy and psoralen with exposure to UV light in vitro

scientific article published on July 1, 2001

Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells.

scientific article

Induction of p-glycoprotein, glutathione-s-transferase-pi, catalase, C-fos and C-erbb1 in rodent cell-lines after exposure to Doxorubicin, ethanol and caffeine ⬇️

scientific article published on January 1, 1995

Inhibition in vivo of the activity of botulinum neurotoxin A by small molecules selected by virtual screening

scientific article

Inhibition of P-glycoprotein at the blood-brain barrier by phytochemicals derived from traditional Chinese medicine.

scientific article published on July 2010

Inhibition of P-glycoprotein by two artemisinin derivatives.

scientific article published on 8 March 2012

Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate

scientific article published in December 2004

Inhibition of c-MYC with involvement of ERK/JNK/MAPK and AKT pathways as a novel mechanism for shikonin and its derivatives in killing leukemia cells

scientific article published on 9 October 2015

Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344

scientific article published on 10 July 2020

Inhibition of epidermal growth factor receptor over-expressing cancer cells by the aphorphine-type isoquinoline alkaloid, dicentrine

scientific article

Inhibition of epidermal growth factor receptor-overexpressing cancer cells by camptothecin, 20-(N,N-diethyl) glycinate

scientific article

Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants.

scientific article published on 27 December 2017

Inhibition of inducible nitric oxide synthase by bis(helenalinyl)glutarate in RAW264.7 macrophages

scientific article

Inhibition of tumor angiogenesis by antibodies, synthetic small molecules and natural products.

scientific article

Insights into apoptotic proteins in chemotherapy: quantification techniques and informing therapy choice

scientific article published on 23 April 2018

Integration of Different "-omics" Technologies Identifies Inhibition of the IGF1R-Akt-mTOR Signaling Cascade Involved in the Cytotoxic Effect of Shikonin against Leukemia Cells

scientific article published on 19 June 2013

Integration of phytochemicals and phytotherapy into cancer precision medicine.

scientific article published on 27 April 2017

Interaction of antihistaminic drugs with human translationally controlled tumor protein (TCTP) as novel approach for differentiation therapy

scientific article

Interactions between artemisinin derivatives and P-glycoprotein

scientific article published on 27 June 2019

Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses

scientific article published on 22 January 2016

Interleukin-6 affects melphalan-induced DNA damage and repair in human multiple myeloma cells.

scientific article

Intra-Articular Injection of Extract Attenuates Pain Behavior and Cartilage Degeneration in Mono-Iodoacetate Induced Osteoarthritic Rats

Intrinsic Overexpression of Two Different Mechanisms of Resistance to Chemotherapy (P-Glycoprotein and GST-π) in Human Endometrial Carcinoma

scientific article published on 01 July 1994

Introduction: Novel hybrid combinations containing synthetic or antibiotic drugs with plant-derived phenolic or terpenoid compounds

scientific article published on 2 November 2017

Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines

scientific article published on March 2004

Investigation of antibacterial activity of rosemary essential oil against Propionibacterium acnes with atomic force microscopy.

scientific article published on 24 September 2007

Investigation of cancer drug resistance mechanisms by phosphoproteomics

scientific article published on 23 July 2020

Is There a Realistic Chance for the Clinical Modulation of Multidrug Resistance?

Isopetasin and S-isopetasin as novel P-glycoprotein inhibitors against multidrug-resistant cancer cells

scientific article published on 10 March 2020

Journal Club

Kaempferol Is an Anti-Inflammatory Compound with Activity towards NF-κB Pathway Proteins

scientific article published on May 2015

Kaempferol derivatives as antiviral drugs against the 3a channel protein of coronavirus.

scientific article published on 23 January 2014

Krebshemmende Wirkung des ätherischen Salbei-Öls auf eine Plattenepithelzellkarzinom-Zelllinie der Mundhöhle (UMSCC1)

scientific article published on 01 December 2011

Laurus nobilis L. Seed Extract Reveals Collateral Sensitivity in Multidrug-Resistant P-Glycoprotein-Expressing Tumor Cells.

scientific article

Lawsone derivatives target the Wnt/β-catenin signaling pathway in multidrug-resistant acute lymphoblastic leukemia cells

scientific article published on 20 October 2017

Leishmaniasis: drug resistance and natural products (review).

scientific article published on September 2008

Long-term add-on therapy (compassionate use) with oral artesunate in patients with metastatic breast cancer after participating in a phase I study (ARTIC M33/2)

scientific article published on 17 September 2018

Lung Cancer Protein Expression Profiles of Smokers and Non-Smokers

scientific article published on 01 May 2004

MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate

scientific article published on 10 February 2019

Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities.

scientific article published on 21 March 2018

Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data.

scientific article

Mechanisms of herb-induced nephrotoxicity.

scientific article published on January 2013

Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy.

scientific article

Medicinal Plants from Near East for Cancer Therapy.

scientific article published on 31 January 2018

Medicinal chemistry of paclitaxel and its analogues

scientific article published on January 2009

Methylthioadenosine phosphorylase as target for chemoselective treatment of T-cell acute lymphoblastic leukemic cells

scientific article published in January 2002

MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60.

scientific article published on September 2010

MicroRNA targeting by quercetin in cancer treatment and chemoprotection

scientific article published on 08 July 2019

Microarray Expression Profiling of ABC Transporters in Human Breast Cancer

scientific article published on 01 March 2006

Microarray analysis of gene expression in medicinal plant research

scientific article published on October 1, 2009

Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins.

scientific article published on 24 January 2006

Microarray-Based Determination of Response of Tumor Cells to Cycloshikonin

Microarray-based Prediction of Cytotoxicity of Tumor Cells to Arsenic Trioxide

scientific article published on 01 September 2004

Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes

scientific article

Microarray-based expression of DNA repair genes does not correlate with growth inhibition of cancer cells by natural products derived from traditional Chinese medicine.

scientific article

Microarray-based mRNA expression profiling of leukemia cells treated with the flavonoid, casticin.

scientific article published on May 2012

Microarray-based prediction of cytotoxicity of tumor cells to cantharidin

scientific article published in March 2005

Microwave-assisted synthesis of new selenazole derivatives with antiproliferative activity.

scientific article published on 19 April 2013

Miltirone Induces G2/M Cell Cycle Arrest and Apoptosis in CCRF-CEM Acute Lymphoblastic Leukemia Cells.

scientific article published on 2 June 2015

Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells.

scientific article published on 5 May 2017

Mode of cell death induction by pharmacological vacuolar H+-ATPase (V-ATPase) inhibition

scientific article published on 20 November 2012

Modulation of P-glycoprotein activity by novel synthetic curcumin derivatives in sensitive and multidrug-resistant T-cell acute lymphoblastic leukemia cell lines.

scientific article published on 15 June 2016

Modulation of P-glycoprotein-mediated multidrug resistance by monoclonal antibodies, immunotoxins or antisense oligodeoxynucleotides in kidney carcinoma and normal kidney cells

scientific article

Modulation of human BCRP (ABCG2) activity by anti-HIV drugs

scientific article published on 3 January 2007

Modulation of the pharmacokinetics, therapeutic and adverse effects of NSAIDs by Chinese herbal medicines

scientific article

Molecular Characterization of a German Variant of Glucose-6-phosphate Dehydrogenase Deficiency (G6PD Aachen)

article

Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine.

scientific article published on 26 February 2018

Molecular Determinants of the Response of Tumor Cells to Boswellic Acids

scientific article (publication date: 19 August 2011)

Molecular Docking Analysis of Steroid-based Copper Transporter 1 Inhibitors

scientific article published on December 2015

Molecular Mechanism of Opioid Analgesia

Molecular Target-Guided Tumor Therapy with Natural Products Derived from Traditional Chinese Medicine

scientific article (publication date: August 2007)

Molecular bases of the poor response of liver cancer to chemotherapy

scientific article published on 12 March 2018

Molecular biology of cantharidin in cancer cells

scientific article (publication date: 4 July 2007)

Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine

scientific article published on 8 January 2011

Molecular docking-based virtual drug screening revealing an oxofluorenyl benzamide and a bromonaphthalene sulfonamido hydroxybenzoic acid as HDAC6 inhibitors with cytotoxicity against leukemia cells

scientific article published on 01 July 2020

Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum

scientific article

Molecular mechanisms of rosmarinic acid from Salvia miltiorrhiza in acute lymphoblastic leukemia cells.

scientific article published on 14 October 2015

Molecular mechanisms underlying St. John's wort drug interactions

scientific article

Molecular modeling of O6-methylguanine-DNA methyltransferase mutant proteins encoded by single nucleotide polymorphisms

scientific article published in October 2005

Molecular modes of action of artesunate in tumor cell lines.

scientific article published in August 2003

Molecular modes of action of cantharidin in tumor cells.

scientific article published on 21 January 2005

Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines

scientific article

Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells

scientific article

Molecular principles of cancer invasion and metastasis (review).

scientific article published on April 2009

Multidrug-Resistenz von Tumoren

Multifactorial Modes of Action of Arsenic Trioxide in Cancer Cells as Analyzed by Classical and Network Pharmacology

scientific article

Multiple modes of cell death in neuroendocrine tumors induced by artesunate

scientific article published on 03 September 2020

Multiple resistance to carcinogens and xenobiotics: P-glycoproteins as universal detoxifiers

scientific article published on 7 February 2017

N-acetylglycoside of oleanolic acid (aridanin) displays promising cytotoxicity towards human and animal cancer cells, inducing apoptotic, ferroptotic and necroptotic cell death

scientific article published on 08 June 2020

Natural Products as Inhibitors of Epidermal Growth Factor Receptor

Natural Products as a Source for New Leads in Cancer Research and Treatment

scientific article published on 15 July 2018

Natural products as promising drug candidates for the treatment of hepatitis B and C.

scientific article

Natural products derived from traditional chinese medicine as novel inhibitors of the epidermal growth factor receptor

scientific article published on December 2010

Natural products in structure-assisted design of molecular cancer therapeutics.

scientific article published on May 2010

Natural products pave their way in cancer therapy

scientific article published on 01 October 2009

Negative pressure cavitation accelerated processing for extraction of main bioactive flavonoids from Radix Scutellariae

Negative pressure cavitation extraction and antioxidant activity of genistein and genistin from the roots of pigeon pea [Cajanus cajan (L.) Millsp.]

Negative pressure cavitation-microwave assisted preparation of extract of Pyrola incarnata Fisch. rich in hyperin, 2'-O-galloylhyperin and chimaphilin and evaluation of its antioxidant activity.

scientific article published on 5 August 2014

Negative-pressure cavitation coupled with aqueous two-phase extraction and enrichment of flavonoids and stilbenes from the pigeon pea leaves and the evaluation of antioxidant activities

scholarly article by Xi-Qing Wang et al published December 2015 in Separation and Purification Technology

Negative-pressure cavitation extraction for the determination of flavonoids in pigeon pea leaves by liquid chromatography-tandem mass spectrometry.

scientific article published on 3 March 2009

Negative-pressure cavitation extraction of cajaninstilbene acid and pinostrobin from pigeon pea [Cajanus cajan (L.) Millsp.] leaves and evaluation of antioxidant activity

Neglected diseases caused by bacterial infections.

scientific article published on January 2010

Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature.

scientific article published on 18 June 2016

Neuroprotection and antioxidative effects of Sijunzi Tang Decoction in the nematode Caenorhabditis elegans

New artesunic acid homodimers: Potent reversal agents of multidrug resistance in leukemia cells

scientific article published on 22 July 2012

New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids

scientific article published on 28 April 2015

New glycosides from Tetracentron sinense and their cytotoxic activity.

scientific article published on September 2006

New phenolics, cytotoxicity and chemosystematic significance of Atriplex semibaccata ⬇️

scholarly article

Nitensidine A, a guanidine alkaloid from Pterogyne nitens, induces osteoclastic cell death

scientific article published on 27 July 2013

Nitensidine A, a guanidine alkaloid from Pterogyne nitens, is a novel substrate for human ABC transporter ABCB1.

scientific article published on 14 October 2013

Nobel Prize for artemisinin brings phytotherapy into the spotlight.

scientific article published on 16 October 2015

North African Medicinal Plants Traditionally Used in Cancer Therapy.

scientific article

Novel artemisinin derivatives with potential usefulness against liver/colon cancer and viral hepatitis.

scientific article published on 29 April 2013

Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology

scientific article published on 20 September 2018

Novel sequential stress model for functional dyspepsia: Efficacy of the herbal preparation STW5.

scientific article

Obituary: Phytomedicine's Associate Editor Professor Dr. David Yue-Wei Lee has passed away

scholarly article

Objectifying acupuncture effects by lung function and numeric rating scale in patients undergoing heart surgery.

scientific article

Optimization of luteolin separation from pigeonpea [Cajanus cajan (L.) Millsp.] leaves by macroporous resins.

scientific article published on 28 November 2006

Organoids of human airways to study infectivity and cytopathy of SARS-CoV-2

scientific article published on 21 May 2020

Organophosphate ester tri-o-cresyl phosphate interacts with estrogen receptor α in MCF-7 breast cancer cells promoting cancer growth

scientific article published on 28 March 2020

Oridonin Targets Multiple Drug-Resistant Tumor Cells as Determined by in Silico and in Vitro Analyses

scientific article published on 16 April 2018

Overcoming drug-resistant cancer by a newly developed copper chelate through host-protective cytokine-mediated apoptosis.

scientific article published on July 2006

Overcoming of P-glycoprotein-mediated multidrug resistance of tumors in vivo by drug combinations

scholarly article by Mohamed Saeed published in September 2014

Overexpression of C-fos and C-erbb1 encoded proteins in squamous-cell carcinomas of the lung of smokers ⬇️

scientific article published on June 1, 1992

Overexpression of P-glycoprotein in human lung carcinoma xenografts after fractionated irradiation in vivo

scientific article

Oxidative stress response of tumor cells: microarray-based comparison between artemisinins and anthracyclines.

scientific article

P-glycoprotein and its inhibition in tumors by phytochemicals derived from Chinese herbs

scientific article published on 21 September 2011

Peptide aptamer identified by molecular docking targeting translationally controlled tumor protein in leukemia cells

scientific article published on 14 March 2016

Personalized cancer medicine: from molecular diagnostics to targeted therapy with natural products.

scientific article published on 19 May 2010

Perspectives for Globalized Natural Medicines

Pharmaceutical care as narrative practice? Rethinking patient-centered care through a pharmacist's perspective.

scientific article published on 20 October 2016

Pharmacogenetic prediction of individual variability in drug response based on CYP2D6, CYP2C9 and CYP2C19 genetic polymorphisms

scientific article

Pharmacogenetics and Pharmacotherapy of Military Personnel Suffering from Post-traumatic Stress Disorder.

scientific article published on 11 November 2016

Pharmacogenetics for individualized cancer chemotherapy.

scientific article

Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in Cancer Cells.

scientific article published on 02 February 2017

Pharmacogenomic Characterization of Cytotoxic Compounds from Salvia officinalis in Cancer Cells

scientific article published on 25 February 2015

Pharmacogenomic and molecular docking studies on the cytotoxicity of the natural steroid wortmannin against multidrug-resistant tumor cells

scientific article published on 26 November 2014

Pharmacogenomic determination of genes associated with sensitivity or resistance of tumor cells to curcumin and curcumin derivatives.

scientific article

Pharmacogenomic identification of c-Myc/Max-regulated genes associated with cytotoxicity of artesunate towards human colon, ovarian and lung cancer cell lines.

scientific article published on 22 April 2010

Pharmacogenomics of Cameroonian traditional herbal medicine for cancer therapy

scientific article

Pharmacogenomics of Scopoletin in Tumor Cells.

scientific article published on 15 April 2016

Pharmacogenomics of a traditional Japanese herbal medicine (Kampo) for cancer therapy.

scientific article

Pharmacogenomics of cantharidin in tumor cells.

scientific article

Pharmacological and chemical features of Nepeta L. genus: Its importance as a therapeutic agent.

scientific article published on 18 October 2017

Phytochemical Analysis and Cytotoxicity Towards Multidrug-Resistant Leukemia Cells of Essential Oils Derived from Lebanese Medicinal Plants

article

Phytochemical and pharmacological properties of essential oils from Cedrus species

scientific article published on 3 July 2017

Phytochemical constituents and chemosystematic significance of Pulicaria jaubertii E.Gamal-Eldin (Asteraceae)

Phytochemical profile and bioactivity of traditional ayurvedic decoctions and hydro-alcoholic macerations of Boerhaavia diffusa L. and Curculigo orchioides Gaertn.

scientific article

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease

scientific article published on 24 November 2017

Phytochemicals for the treatment of inflammatory bowel diseases

Phytochemistry and pharmacogenomics of natural products derived from traditional Chinese medicine and Chinese materia medica with activity against tumor cells

scientific article

Phytochemistry, structural diversity, biological activities and pharmacokinetics of iridoids isolated from various genera of the family Scrophulariaceae Juss.

scientific article published in 2022

Phytomedicine in otorhinolaryngology and pulmonology: clinical trials with herbal remedies.

scientific article published on 20 August 2012

Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cells

scientific article published on 17 August 2019

Plants mentioned in the Islamic Scriptures (Holy Qur'ân and Ahadith): Traditional uses and medicinal importance in contemporary times

scientific article published on 04 June 2019

Plasma pharmacokinetics and tissue distribution study of cajaninstilbene acid in rats by liquid chromatography with tandem mass spectrometry

scientific article published on 15 January 2010

Polo-like kinase 1 as target for cancer therapy

scientific article published on 10 December 2012

Polyacanthoside A, a new oleanane-type triterpenoid saponin with cytotoxic effects from the leaves of Acacia polyacantha (Fabaceae)

scientific article published on 25 June 2018

Polyhydroxylated Steroidal Glycosides from Paris polyphylla

scientific article published on 04 June 2012

Posttraumatic stress disorder among earthquake survivors of the Wenchuan area (Sichuan, China).

scientific article published on 9 December 2014

Potential of Central, Eastern and Western Africa Medicinal Plants for Cancer Therapy: Spotlight on Resistant Cells and Molecular Targets

scientific article

Potential of ‘Omics’ Technologies for Implementation in Research on Phytotherapeutical Toxicology

scientific article published in 2012

Prediction of Cancer Drug Resistance and Implications for Personalized Medicine

scientific article

Prediction of Drug Sensitivity and Resistance of Cancer by Protein Expression Profiling

scientific article published on 01 March 2004

Prediction of broad spectrum resistance of tumors towards anticancer drugs

scientific article

Preface: Approaches of Chinese Medicine to Oncology

article

Preface: Molecular Approaches of Chinese Medicine

article

Preparation and antioxidant activity of Radix Astragali residues extracts rich in calycosin and formononetin

Prevention from radiation damage by natural products

scientific article published on 13 November 2017

Prevention of carcinogenesis and metastasis by Artemisinin-type drugs

Production of rosmarinic acid and salvianolic acid B from callus culture of Salvia miltiorrhiza with cytotoxicity towards acute lymphoblastic leukemia cells

article

Professor Hildebert Wagner celebrates his 90th birthday

scientific article published on 20 July 2019

Prognostic impacts of cytogenetic findings in clear cell renal cell carcinoma: gain of 5q31-qter predicts a distinct clinical phenotype with favorable prognosis ⬇️

scientific article published on 01 November 2001

Prospecting for cytotoxic and antiprotozoal 4-aryl-4H-chromenes and 10-aryldihydropyrano[2,3-f]chromenes

scientific article published on 23 August 2018

Prospective open uncontrolled phase I study to define a well-tolerated dose of oral artesunate as add-on therapy in patients with metastatic breast cancer (ARTIC M33/2).

scientific article published on 24 April 2017

Protein Expression Profiles Indicative for Drug Resistance of Kidney Carcinoma

scientific article published on 01 January 2004

Protein expression profile of primary human squamous cell lung carcinomas indicative of the incidence of metastases

scientific article published on 01 January 2002

Protein expression profiles indicative for drug resistance of non-small cell lung cancer

scientific article published on July 2002

Protein expression profiles of non-small cell lung carcinomas: correlation with histological subtype

scientific article published on 01 July 2002

Putative molecular determinants mediating sensitivity or resistance towards carnosic acid tumor cell responses

scientific article published on 29 June 2020

Qigong therapy for physiotherapists suffering from burnout: a preliminary study

scientific article published in November 2012

Quantitative structure-activity relationship and molecular docking of artemisinin derivatives to vascular endothelial growth factor receptor 1.

scientific article published in April 2015

Rapid microwave-assisted transesterification for the preparation of fatty acid methyl esters from the oil of yellow horn (Xanthoceras sorbifolia Bunge.)

article by Yuangang Zu et al published 18 February 2009 in European Food Research and Technology

Rapid microwave-assisted transesterification of yellow horn oil to biodiesel using a heteropolyacid solid catalyst.

scientific article published on 29 September 2009

Regulation of endoplasmic reticulum stress by hesperetin: Focus on antitumor and cytoprotective effects

scientific article published in 2022

Relationship between EGFR expression and subcellular localization with cancer development and clinical outcome

Relationship between molecular variants and clinical manifestions in twelve glucose-6-phosphate dehydrogenase-deficient patients in Jordan.

scientific article published in January 2005

Repurposing of Bromocriptine for Cancer Therapy

scholarly article by Ean-Jeong Seo et al published 2018 in Frontiers in Pharmacology

Repurposing of artemisinin-type drugs for the treatment of acute leukemia

scientific article published on 30 May 2020

Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicology

scientific article published on 26 December 2019

Repurposing old drugs to fight multidrug resistant cancers

scientific article published on 25 June 2020

Research Highlights: Broken dreams or time to test? Chemoselective treatment of MTAP-deficient tumors with L-alanosine

scientific article published on 01 July 2009

Resin adsorption as a means to enrich rare stilbenes and coumarin from pigeon pea leaves extracts

Resistance mechanisms of cancer cells to the novel vacuolar H(+)-ATPase inhibitor archazolid B.

scientific article

Resistance to Doxorubicin in Tumor Cells in vitro and in vivo after Pretreatment with Verapamil

scientific article published on 01 January 1991

Resveratrol mediated cancer cell apoptosis, and modulation of multidrug resistance proteins and metabolic enzymes

scientific article published on 28 June 2018

Retrospective study of small pet tumors treated with Artemisia annua and iron

scientific article published on 25 November 2019

Reversal of doxorubicin-resistance in sarcoma 180 tumor cells by inhibition of different resistance mechanisms

scientific article

Reversal of drug resistance in P-glycoprotein-expressing T-cell acute lymphoblastic CEM leukemia cells by copper N-(2-hydroxy acetophenone) glycinate and oxalyl bis (N-phenyl) hydroxamic acid.

scientific article published on 10 January 2006

Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes

scientific article published on 28 March 2017

Review of current and "omics" methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms

scientific article published on 22 February 2012

Review. Drug resistance of human immunodeficiency virus and overcoming it by natural products

scientific article published on January 2009

Role of TCTP for Cellular Differentiation and Cancer Therapy.

scientific article published in January 2017

Role of antioxidant genes for the activity of artesunate against tumor cells.

scientific article published on October 2003

Role of glucose-6-phosphate dehydrogenase for oxidative stress and apoptosis.

scientific article published in March 2006

Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate

scientific article

Role of transporter genes in cisplatin resistance.

scientific article

Ruthenium(ii) and palladium(ii) homo- and heterobimetallic complexes: synthesis, crystal structures, theoretical calculations and biological studies

scientific article published on 16 October 2019

SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells

scientific article published on 23 January 2020

Safety and efficacy field study of artesunate for dogs with non-resectable tumours

scientific article published on May 2013

Salvia ceratophylla L. from South of Jordan: new insights on chemical composition and biological activities

scientific article published on 27 August 2020

Screening for natural and derived bio-active compounds in preclinical and clinical studies: One of the frontlines of fighting the coronaviruses pandemic

scientific article published on 29 August 2020

Screening of potent phytochemical inhibitors against SARS-CoV-2 protease and its two Asian mutants

scientific article published on 16 April 2021

Selective growth-inhibition of multidrug-resistant CHO-cells by the monoclonal antibody 265/F4 ⬇️

scientific article published on July 1, 1991

Selective inhibition of P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy

scientific article published on 31 July 2018

Self-medication with nutritional supplements and herbal over-thecounter products

scientific article published in October 2011

Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics

scientific article published on 29 July 2010

Separation of 7-xylosyl-10-deacetyl paclitaxel and 10-deacetylbaccatin III from the remainder extracts free of paclitaxel using macroporous resins

scientific article published on 17 November 2007

Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib

scientific article

Shikonin derivatives for cancer prevention and therapy

scientific article published on 24 May 2019

Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cells.

scientific article

Signal transduction pathways of the epidermal growth factor receptor in colorectal cancer and their inhibition by small molecules

scientific article

Simultaneous determination of main taxoids in Taxus needles extracts by solid-phase extraction-high-performance liquid chromatography with pentafluorophenyl column

scientific article

Sister chromatid exchange-inducing DNA lesions and depression of activation markers on the surface of cultured peripheral blood mononuclear cells after the addition of streptococcal pyrogenic exotoxins A and C

article

Small molecule inhibitors and stimulators of inducible nitric oxide synthase in cancer cells from natural origin (phytochemicals, marine compounds, antibiotics)

scientific article published on 09 January 2020

Specific patterns of DNA copy number gains and losses in eight new glioblastoma multiforme cell lines.

scientific article published on August 2003

Stem Cells, Cancer Stem-Like Cells, and Natural Products ⬇️

scientific article published on 09 May 2012

Steroidal saponins from Raphia vinifera and their Cytotoxic Activity

scientific article published on 01 September 2020

Strategies for overcoming chemotherapy resistance in enterohepatic tumours.

scientific article published on July 2010

Su1582 – Anti-Inflammatory and Epithelial Protective Effects of Herbal Preparation Stw5-Ii on Mouse Intestinal Organoids

scholarly article

Substituted steroidal compounds containing amino and amido groups reverse multidrug resistance of mouse T-lymphoma and two human prostate cancer cell lines in vitro

scientific article

Substrate Specificity of Aglaia loheri Active Isolate towards P-glycoprotein in Multidrug-Resistant Cancer Cells

scientific article published on 01 November 2016

Supercritical carbon dioxide extraction of seed oil from yellow horn (Xanthoceras sorbifolia Bunge.) and its anti-oxidant activity.

scientific article published on 22 December 2009

Synergism between rViscumin and cisplatin is not dependent on ERCC-1 expression.

scientific article published in December 2002

Synergistic inhibition of angiogenesis by artesunate and captopril in vitro and in vivo

scientific article published on 8 October 2013

Synergy and Antagonism of Active Constituents of ADAPT-232 on Transcriptional Level of Metabolic Regulation of Isolated Neuroglial Cells

scientific article (publication date: 2013)

Synergy assessment of fixed combinations of Herba Andrographidis and Radix Eleutherococci extracts by transcriptome-wide microarray profiling.

scientific article published on 20 August 2015

Synergy assessments of plant extracts used in the treatment of stress and aging-related disorders

scholarly article

Synthesis and Cytotoxicity of 1,4-Dihydropyridines and an Unexpected 1,3-Oxazin-6-one

Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF‐CEM and Multidrug‐Resistant CEM/ADR5000 Leukemia Cells

scientific article published in 2021

Synthesis and anti-tumor activity of novel aminomethylated derivatives of isoliquiritigenin.

scientific article

Synthesis and biological evaluation of a D-ring-contracted analogue of lamellarin D.

scientific article published on 9 February 2017

Synthesis and cytotoxic activity of new artemisinin hybrid molecules against human leukemia cells

scientific article published on 20 April 2017

Synthesis and in vitro biological evaluation of novel diaminothiophene scaffolds as antitumor and anti-influenza virus agents. Part 2

scholarly article in RSC Advances, vol. 7 no. 50, 2017

Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells.

scientific article

Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells.

scientific article published in June 2017

Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents

scientific article published on 21 December 2017

Synthesis, Antibacterial and Cytotoxic Activities of Cyanoenonebenzenesulfonamide, Acetamide and Pyridine-3-carbonitrile Derivatives

Synthetic cajanin stilbene acid derivatives inhibit c-MYC in breast cancer cells

scientific article published on 26 February 2015

Systematic Review on Post-Traumatic Stress Disorder Among Survivors of the Wenchuan Earthquake.

scientific article published on 31 May 2015

Target Identification of Active Constituents of Shen Qi Wan to Treat Kidney Yang Deficiency Using Computational Target Fishing and Network Pharmacology

scientific article published on 07 June 2019

Targeting epidermal growth factor receptors and downstream signaling pathways in cancer by phytochemicals

scientific article

Targeting epigenetics in cancer: therapeutic potential of flavonoids

scientific article published on 01 June 2020

Targeting the mitochondrial pathway to induce apoptosis/necrosis through ROS by a newly developed Schiff's base to overcome MDR in cancer.

scientific article

Terpenoid bio-transformations and applications via cell/organ cultures: a systematic review

scientific article published on 30 October 2019

Testing for tumor drug resistance in the age of molecular medicine. A contribution to the Debate Round-Table on Phenotypic and Genotypic Analyses of Multidrug Resistance (MDR) in Clinical Hospital Practice

scientific article published in October 1999

The Antimalarial Activity of Artemisinin is not Stereospecific.

scientific article published on 3 May 2018

The Chinese herbal formula Free and Easy Wanderer ameliorates oxidative stress through KEAP1-NRF2/HO-1 pathway

scientific article

The Combined Effects of Ethylene and MeJA on Metabolic Profiling of Phenolic Compounds in Catharanthus roseus Revealed by Metabolomics Analysis

scientific article published on 07 June 2016

The European directive on traditional herbal medicinal products: friend or foe for plant-based therapies?

scientific article published on 01 April 2012

The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

scientific article published in January 2023

The ability of molecular docking to unravel the controversy and challenges related to P-glycoprotein--a well-known, yet poorly understood drug transporter

scientific article published on 22 April 2014

The activity of Artemisia spp. and their constituents against Trypanosomiasis

scientific article published on 09 June 2018

The alkaloid, soyauxinium chloride, displays remarkable cytotoxic effects towards a panel of cancer cells, inducing apoptosis, ferroptosis and necroptosis

scientific article published on 24 November 2020

The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo.

scientific article published on 21 November 2005

The antibacterial activity of clove essential oil against Propionibacterium acnes and its mechanism of action.

scientific article

The antioxidant 2,3-dichloro,5,8-dihydroxy,1,4-naphthoquinone inhibits acetyl-cholinesterase activity and amyloid β42 aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease

scientific article published on 09 December 2019

The antiviral activities of artemisinin and artesunate.

scientific article published on September 2008

The broad-spectrum antiinfective drug artesunate interferes with the canonical nuclear factor kappa B (NF-κB) pathway by targeting RelA/p65.

scientific article

The emergence of drug resistance to targeted cancer therapies: Clinical evidence

scientific article published on 26 September 2019

The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells.

scientific article published on 17 January 2012

The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage

scientific article

The human ATP-binding cassette transporter genes: from the bench to the bedside

scientific article

The hydrolysis of 6-phosphogluconolactone in the second step of pentose phosphate pathway occurs via a two-water mechanism

scientific article published on 12 June 2018

The lignan, (-)-sesamin reveals cytotoxicity toward cancer cells: pharmacogenomic determination of genes associated with sensitivity or resistance

scientific article published on 18 February 2014

The new journal Phytomedicine Plus to meet the increasing demand for publishing in the fields of phytotherapy and phytopharmacology

scientific article published on 12 September 2020

The pharmacology of the genus Sophora (Fabaceae): An updated review

scientific article published on 21 August 2019

The prophylactic effect of a Eugenia aquea extract against oxidative stress and inflammation associated with the development of arthritis in an adjuvant-induced arthritis rat model

scientific article published on 01 December 2018

The protective role of Ocimum basilicum L. (Basil) against aspirin-induced gastric ulcer in mice: Impact on oxidative stress, inflammation, motor deficits and anxiety-like behavior

scientific article published on 01 August 2018

The road in front of us: Phytomedical research for the years to come

scientific article published on 01 February 2017

The role of copper in drug-resistant murine and human tumors.

scientific article published on 28 October 2008

The role of downstream signaling pathways of the epidermal growth factor receptor for Artesunate's activity in cancer cells.

scientific article

The role of p53 in cancer drug resistance and targeted chemotherapy

scientific article

Theabrownin Inhibits Cell Cycle Progression and Tumor Growth of Lung Carcinoma through c-myc-Related Mechanism

scientific article published on 27 February 2017

Theabrownin triggers DNA damage to suppress human osteosarcoma U2OS cells by activating p53 signalling pathway

scientific article published on 11 July 2018

Therapeutic and diagnostic applications of nanoparticles

scientific article published on March 2011

Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway

scientific article published on 02 January 2020

Threats to human health by great ocean garbage patches

scientific article published on 09 November 2017

Three-dimensional modeling of glucose-6-phosphate dehydrogenase-deficient variants from German ancestry

scientific article

Total coumarins of Hedyotis diffusa induces apoptosis of myelodysplastic syndrome SKM-1 cells by activation of caspases and inhibition of PI3K/Akt pathway proteins

scientific article

Total ginsenosides of Chinese ginseng induces cell cycle arrest and apoptosis in colorectal carcinoma HT-29 cells

scientific article published on 23 July 2018

Toxicities by herbal medicines with emphasis to traditional Chinese medicine

scientific article

Toxicity of the antimalarial artemisinin and its dervatives.

scientific article published on May 2010

Toxicogenomics for the prediction of toxicity related to herbs from traditional Chinese medicine.

scientific article published on 18 October 2010

Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis

scientific article published on 28 September 2020

Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities

scientific article published on 23 February 2012

Traditional Chinese medicines (TCMs) for molecular targeted therapies of tumours.

scientific article published on March 2010

Traditionally used Thai medicinal plants: in vitro anti-inflammatory, anticancer and antioxidant activities

scientific article

Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells.

scientific article published on 20 October 2010

Transport processes of radiopharmaceuticals and -modulators.

scientific article published on 06 June 2011

Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua

scientific article published on 12 April 2014

Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds.

scientific article published on 6 April 2018

Trypanosomatid parasites causing neglected diseases.

scientific article published on January 2010

Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance

scientific article

Tumor microenvironment and epithelial mesenchymal transition as targets to overcome tumor multidrug resistance

scientific article published on 20 June 2020

UV-induced changes of active components and antioxidant activity in postharvest pigeon pea [Cajanus cajan (L.) Millsp.] leaves

scientific article

Unprecedented new nonadecyl para-hydroperoxycinnamate isolated from Erythrina excelsa and its cytotoxic activity

scientific article published on 15 September 2014

Unraveling the role of Globularia species in modern medicine based on evidence from photochemistry, traditional uses and biological activities

scientific article published in April 2025

Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B.

scientific article published on 11 September 2014

Ursolic acid ameliorates stress and reactive oxygen species in C. elegans knockout mutants by the dopamine Dop1 and Dop3 receptors

scientific article published on 11 December 2020

Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation

scientific article published on 01 June 2002

Utilizing inherent fluorescence of therapeutics to analyze real-time uptake and multi-parametric effector kinetics

scientific article published on 3 February 2012

Vaccination and antiviral treatment of neglected diseases caused by flaviviral infections.

scientific article published on January 2011

Variation in contents of main active components and antioxidant activity in leaves of different pigeon pea cultivars during growth.

scientific article

Vitamin K3 chloroderivative (VKT-2) inhibits HDAC6, activates autophagy and apoptosis and inhibits aggresome formation in hepatocellular carcinoma cells

scientific article published on 25 July 2020

Vitamin K3 thio-derivative: a novel specific apoptotic inducer in the doxorubicin-sensitive and -resistant cancer cells

scientific article published on 29 June 2019

Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin--from bench to bedside

scientific article published on 12 March 2007

Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1.

scientific article published on 21 July 2011

Ziziphora tenuior L. essential oil from Dana Biosphere Reserve (Southern Jordan); Chemical characterization and assessment of biological activities

scientific article published on November 2016

mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether.

scientific article published on August 2002

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