List of works - Jed F. Fisher

A Mechanistic Study of the Dihydroflavin Reductive Cleavage of the Dihydroflavin-Tetrahydronaphthalene Epoxide Adducts

scientific article published on 01 June 2000

A computational evaluation of the mechanism of penicillin-binding protein-catalyzed cross-linking of the bacterial cell wall

scientific article

A convenient synthesis of 7 alpha-hydroxycholest-4-en-3-one by the hydroxypropyl-beta-cyclodextrin-facilitated cholesterol oxidase oxidation of 3 beta,7 alpha-cholest-5-ene-3,7-diol

scientific article published on 01 March 1995

Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.

scientific article published in November 2005

Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa

scientific article

Appraisal of a glycopeptide cloaking strategy for a therapeutic oligopeptide: glycopeptide analogs of the renin inhibitor ditekiren

scientific article published on 01 December 1994

Bacterial cell-wall recycling.

scientific article

Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity

scientific article

Beta-lactam resistance in Staphylococcus aureus: the adaptive resistance of a plastic genome.

scientific article

Conformational analyses of thiirane-based gelatinase inhibitors

scientific article published on 5 December 2007

DFT studies of the ring-opening mechanism of SB-3CT, a potent inhibitor of matrix metalloproteinase 2.

scientific article

Elucidation of the structure of the membrane anchor of penicillin-binding protein 5 of Escherichia coli

scientific article

Endless Resistance. Endless Antibiotics?

scientific article (publication date: 2016)

Ensemble of Pinanones from the Permanganate Oxidation of Myrtenal

scientific article published on 23 June 2016

Epidemiological expansion, structural studies, and clinical challenges of new β-lactamases from gram-negative bacteria.

scientific article published on January 2011

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases

scientific article

Fluorescence Assessment of the AmpR-Signaling Network of Pseudomonas aeruginosa to Exposure to β-Lactam Antibiotics

scientific article published on 10 February 2020

Host-guest chemistry of the peptidoglycan

scientific article

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

scientific article

Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders.

scientific article published on January 2009

Inhibitors for Bacterial Cell-Wall Recycling ⬇️

scientific article published on January 19, 2012

Investigation of the mechanism of the cell wall DD-carboxypeptidase reaction of penicillin-binding protein 5 of Escherichia coli by quantum mechanics/molecular mechanics calculations.

scientific article published on 25 June 2008

Kinetics and inhibition of lipid exchange catalyzed by plasma cholesteryl ester transfer protein (lipid transfer protein)

scientific article published on 01 October 1995

Matrix metalloproteinase 2 (MMP2) inhibition: DFT and QM/MM studies of the deprotonation-initialized ring-opening reaction of the sulfoxide analogue of SB-3CT.

scientific article

Matrix metalloproteinase 2 inhibition: combined quantum mechanics and molecular mechanics studies of the inhibition mechanism of (4-phenoxyphenylsulfonyl)methylthiirane and its oxirane analogue.

scientific article

Mechanism-based profiling of MMPs.

scientific article published on January 2010

Messenger Functions of the Bacterial Cell Wall-derived Muropeptides ⬇️

scientific article published on March 27, 2012

Method for measuring the activities of cholesteryl ester transfer protein (lipid transfer protein)

scientific article published on 01 August 1995

Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.

scientific article published on 26 May 2009

Molecular structures and dynamics of the stepwise activation mechanism of a matrix metalloproteinase zymogen: challenging the cysteine switch dogma.

scientific article published on 12 October 2007

Noncovalent binding of a mitomycin C metabolite, 2,7-diaminomitosene, to duplex DNA

scientific article published on 01 April 1995

Peptide to glycopeptide: glycosylated oligopeptide renin inhibitors with attenuated in vivo clearance properties

scientific article published on 01 October 1991

Protonation states of active-site lysines of penicillin-binding protein 6 from Escherichia coli and the mechanistic implications.

scientific article published on 6 February 2014

QM/MM Studies of the Matrix Metalloproteinase 2 (MMP2) Inhibition Mechanism of (S)-SB-3CT and its Oxirane Analogue ⬇️

scientific article published on November 9, 2010

Reductive drug metabolism.

scientific article published on January 1983

Regioselective Control of the SNAr Amination of 5-Substituted-2,4-Dichloropyrimidines Using Tertiary Amine Nucleophiles

scientific article published on 17 July 2015

Structural Analysis of the Role of Pseudomonas aeruginosa Penicillin-Binding Protein 5 in -Lactam Resistance

scientific article

Synthesis and NMR characterization of (Z,Z,Z,Z,E,E,ω)-heptaprenol

scientific article

Synthesis and shift-reagent-assisted full NMR assignment of bacterial (Z8,E2,ω)-undecaprenol.

scientific article published on 15 November 2017

The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA).

scientific article

The future of the β-lactams.

scientific article published on 29 September 2010

The sentinel role of peptidoglycan recycling in the β-lactam resistance of the Gram-negative Enterobacteriaceae and Pseudomonas aeruginosa.

scientific article

Three decades of the class A beta-lactamase acyl-enzyme.

scientific article published on October 2009

Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics.

scientific article

β-Lactam Resistance Mechanisms: Gram-Positive Bacteria and Mycobacterium tuberculosis

scientific article published on 18 April 2016

β-Lactams against the Fortress of the Gram-Positive <i>Staphylococcus aureus</i> Bacterium

scientific article published on 29 December 2020

List of works by Jed F. Fisher

A Mechanistic Study of the Dihydroflavin Reductive Cleavage of the Dihydroflavin-Tetrahydronaphthalene Epoxide Adducts

A computational evaluation of the mechanism of penicillin-binding protein-catalyzed cross-linking of the bacterial cell wall

A convenient synthesis of 7 alpha-hydroxycholest-4-en-3-one by the hydroxypropyl-beta-cyclodextrin-facilitated cholesterol oxidase oxidation of 3 beta,7 alpha-cholest-5-ene-3,7-diol

Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.

Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa

Appraisal of a glycopeptide cloaking strategy for a therapeutic oligopeptide: glycopeptide analogs of the renin inhibitor ditekiren

Bacterial cell-wall recycling.

Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity

Beta-lactam resistance in Staphylococcus aureus: the adaptive resistance of a plastic genome.

Conformational analyses of thiirane-based gelatinase inhibitors

DFT studies of the ring-opening mechanism of SB-3CT, a potent inhibitor of matrix metalloproteinase 2.

Elucidation of the structure of the membrane anchor of penicillin-binding protein 5 of Escherichia coli

Endless Resistance. Endless Antibiotics?

Ensemble of Pinanones from the Permanganate Oxidation of Myrtenal

Epidemiological expansion, structural studies, and clinical challenges of new β-lactamases from gram-negative bacteria.

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases

Fluorescence Assessment of the AmpR-Signaling Network of Pseudomonas aeruginosa to Exposure to β-Lactam Antibiotics

Host-guest chemistry of the peptidoglycan

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders.

Inhibitors for Bacterial Cell-Wall Recycling ⬇️

Investigation of the mechanism of the cell wall DD-carboxypeptidase reaction of penicillin-binding protein 5 of Escherichia coli by quantum mechanics/molecular mechanics calculations.

Kinetics and inhibition of lipid exchange catalyzed by plasma cholesteryl ester transfer protein (lipid transfer protein)

Matrix metalloproteinase 2 (MMP2) inhibition: DFT and QM/MM studies of the deprotonation-initialized ring-opening reaction of the sulfoxide analogue of SB-3CT.

Matrix metalloproteinase 2 inhibition: combined quantum mechanics and molecular mechanics studies of the inhibition mechanism of (4-phenoxyphenylsulfonyl)methylthiirane and its oxirane analogue.

Mechanism-based profiling of MMPs.

Messenger Functions of the Bacterial Cell Wall-derived Muropeptides ⬇️

Method for measuring the activities of cholesteryl ester transfer protein (lipid transfer protein)

Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.

Molecular structures and dynamics of the stepwise activation mechanism of a matrix metalloproteinase zymogen: challenging the cysteine switch dogma.

Noncovalent binding of a mitomycin C metabolite, 2,7-diaminomitosene, to duplex DNA

Peptide to glycopeptide: glycosylated oligopeptide renin inhibitors with attenuated in vivo clearance properties

Protonation states of active-site lysines of penicillin-binding protein 6 from Escherichia coli and the mechanistic implications.

QM/MM Studies of the Matrix Metalloproteinase 2 (MMP2) Inhibition Mechanism of (S)-SB-3CT and its Oxirane Analogue ⬇️

Reductive drug metabolism.

Regioselective Control of the SNAr Amination of 5-Substituted-2,4-Dichloropyrimidines Using Tertiary Amine Nucleophiles

Structural Analysis of the Role of Pseudomonas aeruginosa Penicillin-Binding Protein 5 in -Lactam Resistance

Synthesis and NMR characterization of (Z,Z,Z,Z,E,E,ω)-heptaprenol

Synthesis and shift-reagent-assisted full NMR assignment of bacterial (Z8,E2,ω)-undecaprenol.

The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA).

The future of the β-lactams.

The sentinel role of peptidoglycan recycling in the β-lactam resistance of the Gram-negative Enterobacteriaceae and Pseudomonas aeruginosa.

Three decades of the class A beta-lactamase acyl-enzyme.

Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics.

β-Lactam Resistance Mechanisms: Gram-Positive Bacteria and Mycobacterium tuberculosis

β-Lactams against the Fortress of the Gram-Positive <i>Staphylococcus aureus</i> Bacterium