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List of works by Nicolas Grégoire

A Population WB-PBPK Model of Colistin and its Prodrug CMS in Pigs: Focus on the Renal Distribution and Excretion

scientific article published on 12 March 2018

A Whole-Body Physiologically Based Pharmacokinetic Model for Colistin and Colistin methanesulfonate (CMS) in Rat.

scientific article published on 17 April 2018

A preclinical pharmacokinetic modeling approach to the biopharmaceutical characterization of immediate and microsphere-based sustained release pulmonary formulations of rifampicin.

scientific article published on 16 November 2012

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats. 4. Aztreonam.

scientific article

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 3. Tobramycin.

scientific article published on 3 August 2015

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 6. Aminoglycosides

scientific article published on 24 September 2018

Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 1. Ciprofloxacin, moxifloxacin, and grepafloxacin.

scientific article

Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 2. Colistin

scientific article

Clinical Pharmacokinetics and Pharmacodynamics of Colistin.

scientific article

Colistin Pharmacokinetics in Pediatrics

scientific article published on 4 December 2017

Colistin distribution in the peritoneal fluid of a patient with severe peritonitis.

scientific article published on 30 April 2012

Colistin in critically ill patients

scientific article published on December 17, 2012

Colistin pharmacokinetics: the fog is lifting

scientific article published on 11 October 2011

Comparison of intrapulmonary and systemic pharmacokinetics of colistin methanesulfonate (CMS) and colistin after aerosol delivery and intravenous administration of CMS in critically ill patients.

scientific article

Convulsions and apnoea in a patient infected with New Delhi metallo-β-lactamase-1 Escherichia coli treated with colistin.

scientific article

Distinguishing Antimicrobial Models with Different Resistance Mechanisms via Population Pharmacodynamic Modeling

scientific article

Lack of effect of extracorporeal membrane oxygenation on tigecycline pharmacokinetics

scientific article published on 29 December 2011

Lack of experimental evidence to support mcr-1-positive Escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets.

scientific article

Microdialysis study of cefotaxime cerebral distribution in patients with acute brain injury.

scientific article published on 09 April 2013

Modeling Approach To Characterize Intraocular Doripenem Pharmacokinetics after Intravenous Administration to Rabbits, with Tentative Extrapolation to Humans ⬇️

scientific article published on April 23, 2012

Nefopam pharmacokinetics in patients with end-stage renal disease.

scientific article published on November 2010

New colistin population pharmacokinetic data in critically ill patients suggesting an alternative loading dose rationale.

scientific article

Pharmacodynamic modelling of β-lactam/β-lactamase inhibitor checkerboard data: illustration with aztreonam-avibactam

scientific article published on 10 December 2018

Pharmacokinetics of Colistin Methansulphonate (CMS) and Colistin after CMS Nebulisation in Baboon Monkeys

scientific article published on 4 June 2015

Pharmacokinetics of Colistin and Colistimethate Sodium After a Single 80-mg Intravenous Dose of CMS in Young Healthy Volunteers

scientific article published on May 4, 2011

Pharmacokinetics of Polymyxins in Animals

scientific article published on 01 January 2019

Pharmacokinetics of colistin after nebulization or intravenous administration of colistin methanesulphonate (Colimycin®) to cystic fibrosis patients

scientific article published on 06 September 2019

Pharmacokinetics of colistin in a 8-year-old child with acute bone infection

scientific article published on 30 April 2018

Pharmacokinetics of intravenous and nebulized gentamicin in critically ill patients

scientific article published on 01 October 2018

Pharmacokinetics of nebulized colistin methanesulfonate in critically ill patients

scientific article published on 01 September 2017

Pharmacokinetics of tedizolid in obese patient after bariatric surgery: a case report

scientific article published on 29 January 2018

Population Pharmacokinetics of Amitriptyline After Intrathecal, Epidural, and Intravenous Administration in Sheep

scientific article

Population Pharmacokinetics of Colistin Methanesulfonate and Colistin in Critically Ill Patients with Acute Renal Failure Requiring Intermittent Hemodialysis.

scientific article published on 4 January 2016

Population pharmacokinetic analysis of Ibuprofen enantiomers in preterm newborn infants.

scientific article

Population pharmacokinetics of daptomycin in critically ill patients with various degrees of renal impairment

scientific article published on 01 January 2019

Population pharmacokinetics of ibuprofen enantiomers in very premature neonates.

scientific article published in October 2004

Preclinical Pharmacokinetic and Pharmacodynamic Data To Support Cefoxitin Nebulization for the Treatment of Mycobacterium abscessus

scientific article published on 24 June 2019

Pulmonary delivery of pyrazinamide-loaded large porous particles.

scientific article published on 30 May 2015

Pulmonary pharmacokinetics of levofloxacin in rats after aerosolization of immediate-release chitosan or sustained-release PLGA microspheres

scientific article published on 13 August 2016

Reassessing the dosing of cefoxitin prophylaxis during major abdominal surgery: insights from microdialysis and population pharmacokinetic modelling

scientific article published on 01 July 2019

Safety and pharmacokinetics of paracetamol following intravenous administration of 5 g during the first 24 h with a 2-g starting dose

scientific article published on 01 March 2007

Semi-mechanistic PK/PD modelling of combined polymyxin B and minocycline against a polymyxin-resistant strain of Acinetobacter baumannii

scientific article published on 30 January 2020

Semimechanistic Pharmacodynamic Modeling of Aztreonam-Avibactam Combination to Understand Its Antimicrobial Activity Against Multidrug-Resistant Gram-Negative Bacteria

scientific article published on 16 August 2019

The inoculum effect of Escherichia coli expressing mcr-1 or not on colistin activity in a murine model of peritonitis

scientific article published on 05 September 2019

[Anticancer drugs pharmacokinetics update]

scientific article published on 01 January 1999

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