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List of works by Huub Hoefsloot

A classification model for the Leiden proteomics competition

scientific article

A critical assessment of SELDI-TOF-MS for biomarker discovery in serum and tissue of patients with an ovarian mass.

scientific article

A critical assessment of feature selection methods for biomarker discovery in clinical proteomics

scientific article published on 31 October 2012

ANOVA-simultaneous component analysis (ASCA): a new tool for analyzing designed metabolomics data

scientific article

Analysis of longitudinal metabolomics data

scientific article

Assessing the statistical validity of proteomics based biomarkers

scientific article published on 27 April 2007

Between Metabolite Relationships: an essential aspect of metabolic change

scientific article published on May 24, 2011

Biomarkers for lysosomal storage disorders: identification and application as exemplified by chitotriosidase in Gaucher disease

scientific article

Capturing Arabidopsis root architecture dynamics with ROOT-FIT reveals diversity in responses to salinity.

scientific article

Centering, scaling, and transformations: improving the biological information content of metabolomics data

scientific article

Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression

scientific article published on August 2017

Classification-based comparison of pre-processing methods for interpretation of mass spectrometry generated clinical datasets.

scientific article

Computational modeling of the human serum proteome response to colon resection surgery

scientific article

Correlated measurement error hampers association network inference.

scientific article published on 2 May 2014

Crossfit analysis: a novel method to characterize the dynamics of induced plant responses

scientific article

Culturing Synechocystis sp. Strain PCC 6803 with N2 and CO2 in a Diel Regime Reveals Multiphase Glycogen Dynamics with Low Maintenance Costs

scientific article

Detecting regulatory mechanisms in endocrine time series measurements

scientific article

Discovering gene expression patterns in time course microarray experiments by ANOVA-SCA.

scientific article published on 22 May 2007

Endocrine pulse identification using penalized methods and a minimum set of assumptions

scientific article published on 27 October 2009

Gaucher disease: a model disorder for biomarker discovery

scientific article published on August 2009

Genetic Components of Root Architecture Remodeling in Response to Salt Stress.

scientific article published on 7 November 2017

Genome-wide analysis of yeast stress survival and tolerance acquisition to analyze the central trade-off between growth rate and cellular robustness

scientific article published on 30 September 2011

Genome-wide mapping of transcriptional enhancer candidates using DNA and chromatin features in maize

scientific article published on 21 July 2017

Global test for metabolic pathway differences between conditions.

scientific article

How informative is your kinetic model?: using resampling methods for model invalidation

scientific article

How to distinguish healthy from diseased? Classification strategy for mass spectrometry-based clinical proteomics

scientific article

Identification of Analytical Factors Affecting Complex Proteomics Profiles Acquired in a Factorial Design Study with Analysis of Variance: Simultaneous Component Analysis

scientific article published on 9 March 2016

Improved cholesterol phenotype analysis by a model relating lipoprotein life cycle processes to particle size

scientific article published on 10 June 2009

Individual differences in metabolomics: individualised responses and between-metabolite relationships

scientific article published on March 15, 2012

Inferring differences in the distribution of reaction rates across conditions

scientific article published on 11 July 2012

Inferring protein-protein interaction complexes from immunoprecipitation data

scientific article

Integrative Analysis of Proteome and Transcriptome Dynamics during Bacillus subtilis Spore Revival

scientific article published on 05 August 2020

Inversion of peak elution order prevents uniform time alignment of complex liquid-chromatography coupled to mass spectrometry datasets

scientific article published on 13 November 2014

MetDFBA: incorporating time-resolved metabolomics measurements into dynamic flux balance analysis

scientific article

Multilevel data analysis of a crossover designed human nutritional intervention study

scientific article

Multivariate paired data analysis: multilevel PLSDA versus OPLSDA.

scientific article

Network identification of hormonal regulation

scientific article

Optimized time alignment algorithm for LC-MS data: correlation optimized warping using component detection algorithm-selected mass chromatograms

scientific article

Profiling of liquid crystal displays with Raman spectroscopy: preprocessing of spectra

scientific article published in March 2005

Quantitative proteomics analysis of an ethanol- and a lactate-producing mutant strain of Synechocystis sp. PCC6803

scientific article

Reverse engineering of metabolic networks, a critical assessment

scientific article

Scaling in ANOVA-simultaneous component analysis

scientific article published on 14 February 2015

Selection of optimal process analyzers for plant-wide monitoring.

scientific article

Simulation of the rate of transfer of antibiotic resistance between Escherichia coli strains cultured under well controlled environmental conditions

scientific article published on 18 April 2014

Statistical data processing in clinical proteomics

scientific article

Strategies for individual phenotyping of linoleic and arachidonic acid metabolism using an oral glucose tolerance test

scientific article published on 18 March 2015

The photographer and the greenhouse: how to analyse plant metabolomics data

scientific article

Time alignment algorithms based on selected mass traces for complex LC-MS data

scientific article

Time-series analysis of the transcriptome and proteome of Escherichia coli upon glucose repression

scientific article published on 3 June 2015

To aggregate or not to aggregate high-dimensional classifiers

scientific article

Toward Reliable Lipoprotein Particle Predictions from NMR Spectra of Human Blood: An Interlaboratory Ring Test

scientific article published on 10 July 2017

Towards a Hierarchical Strategy to Explore Multi-Scale IP/MS Data for Protein Complexes

scientific article

Validation and selection of ODE based systems biology models: how to arrive at more reliable decisions

scientific article published on 8 July 2015