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List of works by Colin R. Goding

A phosphatidylinositol 3-kinase-Pax3 axis regulates Brn-2 expression in melanoma

scientific article

ABCB5 is activated by MITF and β-catenin and is associated with melanoma differentiation

scientific article published on 28 October 2019

Afamelanotide for Erythropoietic Protoporphyria

scientific article published on July 2015

Alpha-MSH regulates intergenic splicing of MC1R and TUBB3 in human melanocytes

scientific article published on 11 November 2010

Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion

scientific article published on 4 November 2015

Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development

scientific article published on July 2013

BRN2 is a non-canonical melanoma tumor-suppressor

scientific article published on 17 June 2021

Beta-catenin in the melanocyte lineage

scientific article

Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development

scientific article

Biological and mathematical modeling of melanocyte development

scientific article published in September 2011

Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter.

scientific article

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

scientific article published on 01 October 2008

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin

scientific article

Browsing issues

scientific article published on 01 February 2009

CBP/p300 as a co-factor for the Microphthalmia transcription factor ⬇️

article by S Sato et al published 26 June 1997 in Oncogene

Cancer stem cells versus phenotype-switching in melanoma

scientific article

Cancer: pathological nuclear reprogramming?

scientific article published on 17 July 2014

Cell and molecular biology: a new section joins the fight against cancer

scientific article published on 12 December 2017

Cell cycle regulation of the T-box transcription factor tbx2.

scientific article

Chromatin barcodes as biomarkers for melanoma

scientific article

Cloning and functional analysis of ascidian Mitf in vivo: insights into the origin of vertebrate pigment cells

scientific article published in December 2003

Correction: The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression

scientific article published on 01 December 2020

Dicing with death: Mitf regulates DICER

scientific article published on 16 June 2010

Directed phenotype switching as an effective antimelanoma strategy.

scientific article

E pluribus unum

scholarly article by Colin R. Goding published 21 April 2008 in Pigment Cell & Melanoma Research

EDITORIAL: Its all in the name

scientific article published on 01 February 2008

ERK-regulated differential expression of the Mitf 6a/b splicing isoforms in melanoma

scientific article

Editorial

Editorial: A colourful first 20 years

Editorial: A model, MIA and Sox

scientific article published on 01 April 2005

Editorial: Beyond the pale

scientific article published on 01 December 2006

Editorial: Black to the future - the next 5 years

scientific article published on 01 February 2005

Editorial: Colour and form

Editorial: For support and illumination*

Editorial: History and all that

scientific article published on 01 June 2006

Editorial: It's back -http://www.pigment.org

Editorial: It's good to talk

scientific article published on 01 December 2005

Editorial: Melanosomes, light and transposable elements

scientific article published on 01 October 2005

Editorial: Vigour, vitiligo and the RPE

scientific article published on 01 October 2006

Editorial: melanomas and Wnts.

scientific article published in June 2005

Environmental issues

scholarly article by Colin R. Goding published June 2008 in Pigment Cell & Melanoma Research

Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells

scientific article published on 03 June 2021

Finding a niche

Fishful thinking: the rise and fall of MITF in melanoma

scientific article

From mechanistic insights to therapeutic applications

scientific article published in April 2009

Genesis and Nemesis

scientific article published on 01 December 2008

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 mice

scientific article published on 02 April 2019

Interaction between p53 mutation and a somatic HDMX biomarker better defines metastatic potential in breast cancer.

scientific article

Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination

scientific article

KITD816V Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma

scientific article published on 5 June 2017

Let’s stick together

Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers

scientific article

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

scientific article published on 15 December 2014

MC1R is a potent regulator of PTEN after UV exposure in melanocytes

scientific article published on August 2013

MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment

scientific article

MITF controls the TCA cycle to modulate the melanoma hypoxia response

scientific article published on 08 July 2019

MITF is a critical regulator of the carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in malignant melanoma

scientific article published on 24 August 2015

Macrophage Cytoplasmic Transfer in Melanoma Invasion

scientific article published in December 2017

Many are called, few are chosen

scientific article published on 01 June 2011

Melanocyte-specific expression of the human tyrosinase promoter: activation by the microphthalmia gene product and role of the initiator.

scientific article

Melanocytes: the new Black

scientific article published on 7 October 2006

Melanoma senescence: HDAC1 in focus

scientific article published on 01 October 2007

Melanoma, making a difference

scientific article published on 01 December 2007

Melanoma: markers and epigenetics

Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL expression

scientific article published on 11 April 2014

Microphthalmic-Associated Transcription Factor Integrates Melanocyte Biology and Melanoma Progression

scientific article published on 01 February 2006

Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1.

scientific article

Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

scientific article

Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin

scientific article published on December 2016

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.

scientific article

Oncogenic B-RAF(V600E) signaling induces the T-Box3 transcriptional repressor to repress E-cadherin and enhance melanoma cell invasion

scientific article

PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration

scientific article published on January 2011

Palmitoylation-dependent activation of MC1R prevents melanomagenesis

scientific article published on 6 September 2017

Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer

scientific article published on 30 June 2020

Pax3 and Regulation of the Melanocyte-specific Tyrosinase-related Protein-1 Promoter

scientific article published on 01 September 1999

Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation

scientific article published on 30 January 2012

Positive and negative elements regulate a melanocyte-specific promoter

scientific article

Precise nucleosome positioning and the TATA box dictate requirements for the histone H4 tail and the bromodomain factor Bdf1.

scientific article

Reciprocal Regulation of BRN2 and NOTCH1/2 Signaling Synergistically Drives Melanoma Cell Migration and Invasion

scientific article published in 2022

Regulated displacement of TBP from the PHO8 promoter in vivo requires Cbf1 and the Isw1 chromatin remodeling complex

scientific article

Regulation of melanoblast and retinal pigment epithelium development by Xenopus laevis Mitf

scientific article published in November 2005

Requirements for Chromatin Modulation and Transcription Activation by the Pho4 Acidic Activation Domain ⬇️

scientific article published on October 1, 1998

Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP.

scientific article

Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP

scientific article

S1 sensitive sites in adenovirus DNA.

scientific article published on January 1983

Saccharomyces cerevisiae C1D is implicated in both non-homologous DNA end joining and homologous recombination

scientific article published in November 2002

Sensitivity to anti-BRAF therapy: lost in translation.

scientific article published on 30 September 2014

So long, and thanks for all the…

scholarly article by Colin R. Goding published December 2009 in Pigment Cell & Melanoma Research

Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma.

scientific article published on 28 November 2017

T-box factors: targeting to chromatin and interaction with the histone H3 N-terminal tail.

scientific article

T-box transcription factors in cancer biology

scientific article

TBX2 controls a proproliferative gene expression program in melanoma

scientific article published on 24 November 2021

TBX2 expression is regulated by PAX3 in the melanocyte lineage

scientific article

TBX3 and its splice variant TBX3 + exon 2a are functionally similar.

scientific article published on 26 April 2008

Tanning, p53 and PCMR

scientific article published on 01 October 2008

Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation.

scientific article published on 23 April 2009

Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads

scientific article published on 20 February 2019

Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells

scientific article published on 17 October 2016

Targeting the lncRNA SAMMSON Reveals Metabolic Vulnerability in Melanoma.

scientific article

Targeting the microphthalmia basic helix-loop-helix-leucine zipper transcription factor to a subset of E-box elements in vitro and in vivo

scientific article

Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor

scientific article

Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas

scientific article

Tbx3 represses E-cadherin expression and enhances melanoma invasiveness.

scientific article

The Brn-2 transcription factor links activated BRAF to melanoma proliferation

scientific article

The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth

scientific article published on September 2015

The ISWI and CHD1 chromatin remodelling activities influence ADH2 expression and chromatin organization

scientific article

The RING domain of RAG1 ubiquitylates histone H3: a novel activity in chromatin-mediated regulation of V(D)J joining

scientific journal article

The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression.

scientific article

The adenovirus-2 EIIa early gene promoter: sequences required for efficient in vitro and in vivo transcription

scientific article

The anti-proliferative function of the TGF-β1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3

scientific article

The eyes have it

scientific article published on 01 October 2009

The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes

scientific article (publication date: 21 July 2000)

The impact of PCMR

scientific article published on 01 August 2008

The importance of p53 pathway genetics in inherited and somatic cancer genomes.

scientific article published on March 2016

The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma

scientific article published on September 2003

The microphthalmia-associated transcription factor Mitf interacts with beta-catenin to determine target gene expression

scientific article published on 25 September 2006

The new black

scientific article published on 01 June 2009

The path of least resistance: enhancing the effectiveness of BRAF inhibitors

scientific article published on 07 March 2013

The protective role of DOT1L in UV-induced melanomagenesis

scientific article published on 17 January 2018

The retinoblastoma protein modulates Tbx2 functional specificity

scientific article published on 9 June 2010

The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression

scientific article published on 25 September 2020

The transcription network regulating melanocyte development and melanoma

scientific article published in August 2004

Three BRNs are better than two.

scientific article

Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma

scientific article

Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.

scientific article published on 17 January 2017

UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1)

scientific journal article

UV-mediated regulation of the anti-senescence factor Tbx2.

scientific article published on 19 November 2007

Upwards and onwards

scholarly article by Colin R. Goding published August 2009 in Pigment Cell & Melanoma Research

Viral mutations enhance the Max binding properties of the vMyc b-HLH-LZ domain.

scientific article

pWITCH: a versatile two-hybrid assay vector for the production of epitope/activation domain-tagged proteins both in vitro and in yeast

scientific article published on 01 November 1995

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