List of works - Elena Volpi

A Phase I Randomized Clinical Trial of Evidence-Based, Pragmatic Interventions to Improve Functional Recovery After Hospitalization in Geriatric Patients

scientific article published on 01 September 2019

A Randomized Controlled Pilot Trial of Interventions to Improve Functional Recovery After Hospitalization in Older Adults: Feasibility and Adherence.

scientific article published on 07 June 2017

A dose-response study of growth hormone (GH) replacement on whole body protein and lipid kinetics in GH-deficient adults

scientific article published on 01 February 1998

A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults.

scientific article

A soy, whey and caseinate blend extends postprandial skeletal muscle protein synthesis in rats

scientific article

Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin.

scientific article

Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism

scientific article published on 23 January 2013

Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation.

scientific article

Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

scientific article

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

scientific article

Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy.

scientific article

Amino acid metabolism and regulatory effects in aging

scientific article

Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle

scientific article published on 14 March 2008

An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle

scientific article

Androgen Therapy and Rehospitalization in Older Men With Testosterone Deficiency

scientific article published on 6 April 2016

Androgen therapy induces muscle protein anabolism in older women.

scientific article

Androstenedione does not stimulate muscle protein anabolism in young healthy men

scientific article published on 01 January 2000

Basal muscle intracellular amino acid kinetics in women and men.

scientific article

Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults.

scientific article

Blood flow restriction during low-intensity resistance exercise increases S6K1 phosphorylation and muscle protein synthesis

scientific article published on 14 June 2007

Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men

scientific article

Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans

scientific article published on 26 May 2016

Brown Adipose Tissue Is Linked to a Distinct Thermoregulatory Response to Mild Cold in People

scientific article published on 19 April 2016

Challenges and new opportunities for clinical nutrition interventions in the aged

scientific article

Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.

scientific article published on 27 March 2015

Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling

scientific article published on April 2012

Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage

scientific article

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

scientific article

Effect of essential amino acid supplementation and aerobic exercise on insulin sensitivity in healthy older adults: A randomized clinical trial

scientific article published on 28 June 2019

Effect of insulin on human skeletal muscle protein synthesis is modulated by insulin-induced changes in muscle blood flow and amino acid availability

scientific article

Efficacy and Safety of Leucine Supplementation in the Elderly.

scientific article

Endothelial function and the regulation of muscle protein anabolism in older adults.

scientific article published on 17 August 2012

Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle.

scientific article

Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group

scientific article

Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women

scientific article

Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle.

scientific article published on October 2013

Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis

scientific article published on 11 September 2008

Human muscle gene expression following resistance exercise and blood flow restriction.

scientific article published on April 2008

Identifying effective and feasible interventions to accelerate functional recovery from hospitalization in older adults: A randomized controlled pilot trial

scientific article published on 10 May 2016

Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells.

scientific article published on 20 March 2014

Insulin resistance of muscle protein metabolism in aging

scientific article

Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?

scientific article published on 26 November 2012

Kyphoplasty for vertebral augmentation in the elderly with osteoporotic vertebral compression fractures: scenarios and review of recent studies.

scientific article

Leucine-enriched amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men.

scientific article

Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle.

scientific article published on 04 December 2007

Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids

scientific article

Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle

scientific article published on 2 June 2015

Muscle Protein Anabolic Resistance to Essential Amino Acids Does Not Occur in Healthy Older Adults Before or After Resistance Exercise Training.

scientific article

Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise.

scientific article

Muscle protein metabolism responds similarly to exogenous amino acids in healthy younger and older adults during NO-induced hyperemia.

scientific article published on 31 August 2011

Muscle tissue changes with aging

scientific article

Novel noninvasive breath test method for screening individuals at risk for diabetes.

scientific article published on 15 December 2008

Nutrition and sarcopenia of ageing.

scientific article published in June 2004

PAX7+ satellite cells in young and older adults following resistance exercise

scientific article

Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women

scientific article published on 6 September 2016

Post-absorptive muscle protein turnover affects resistance training hypertrophy.

scientific article

Postexercise protein metabolism in older and younger men following moderate-intensity aerobic exercise.

scientific article

Protein Requirements in Critically Ill Older Adults.

scientific article published on 20 March 2018

Protein Supplementation Does Not Affect Myogenic Adaptations to Resistance Training.

scientific article published on 14 February 2017

Protein Supplementation Has Minimal Effects on Muscle Adaptations during Resistance Exercise Training in Young Men: A Double-Blind Randomized Clinical Trial

scientific article published on 27 July 2016

Protein intake and muscle function in older adults

scientific article

Protein metabolism in women and men: similarities and disparities.

scientific article

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling

scientific article

Quantification of muscle triglyceride synthesis rate requires an adjustment for total triglyceride content

scientific article published on 21 August 2018

Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle

scientific article published on 06 September 2012

Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle.

scientific article

Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery.

scientific article published on 09 October 2008

Sequential muscle biopsies during a 6-h tracer infusion do not affect human mixed muscle protein synthesis and muscle phenylalanine kinetics.

scientific article published on 19 August 2008

Sex-dependent difference in the relationship between adipose-tissue cholesterol efflux and estradiol concentrations in young healthy humans

scientific article published on 11 July 2017

Short-term insulin and nutritional energy provision do not stimulate muscle protein synthesis if blood amino acid availability decreases

scientific article

Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.

scientific article

Soy-Dairy Protein Blend or Whey Protein Isolate Ingestion Induces Similar Postexercise Muscle Mechanistic Target of Rapamycin Complex 1 Signaling and Protein Synthesis Responses in Older Men.

scientific article published on 26 October 2016

Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle.

scientific article

Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism.

scientific article

Testing the effects of narrative and play on physical activity among breast cancer survivors using mobile apps: study protocol for a randomized controlled trial

scientific article

The impact of postexercise essential amino acid ingestion on the ubiquitin proteasome and autophagosomal-lysosomal systems in skeletal muscle of older men.

scientific article

The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly.

scientific article

Vitamin D and endothelial vasodilation in older individuals: data from the PIVUS study

scientific article

Whey Protein Hydrolysate Increases Amino Acid Uptake, mTORC1 Signaling, and Protein Synthesis in Skeletal Muscle of Healthy Young Men in a Randomized Crossover Trial

scientific article published on 01 July 2019

List of works by Elena Volpi

A Phase I Randomized Clinical Trial of Evidence-Based, Pragmatic Interventions to Improve Functional Recovery After Hospitalization in Geriatric Patients

A Randomized Controlled Pilot Trial of Interventions to Improve Functional Recovery After Hospitalization in Older Adults: Feasibility and Adherence.

A dose-response study of growth hormone (GH) replacement on whole body protein and lipid kinetics in GH-deficient adults

A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults.

A soy, whey and caseinate blend extends postprandial skeletal muscle protein synthesis in rats

Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin.

Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism

Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation.

Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy.

Amino acid metabolism and regulatory effects in aging

Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle

An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle

Androgen Therapy and Rehospitalization in Older Men With Testosterone Deficiency

Androgen therapy induces muscle protein anabolism in older women.

Androstenedione does not stimulate muscle protein anabolism in young healthy men

Basal muscle intracellular amino acid kinetics in women and men.

Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults.

Blood flow restriction during low-intensity resistance exercise increases S6K1 phosphorylation and muscle protein synthesis

Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men

Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans

Brown Adipose Tissue Is Linked to a Distinct Thermoregulatory Response to Mild Cold in People

Challenges and new opportunities for clinical nutrition interventions in the aged

Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.

Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling

Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

Effect of essential amino acid supplementation and aerobic exercise on insulin sensitivity in healthy older adults: A randomized clinical trial

Effect of insulin on human skeletal muscle protein synthesis is modulated by insulin-induced changes in muscle blood flow and amino acid availability

Efficacy and Safety of Leucine Supplementation in the Elderly.

Endothelial function and the regulation of muscle protein anabolism in older adults.

Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle.

Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group

Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women

Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle.

Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis

Human muscle gene expression following resistance exercise and blood flow restriction.

Identifying effective and feasible interventions to accelerate functional recovery from hospitalization in older adults: A randomized controlled pilot trial

Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells.

Insulin resistance of muscle protein metabolism in aging

Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?

Kyphoplasty for vertebral augmentation in the elderly with osteoporotic vertebral compression fractures: scenarios and review of recent studies.

Leucine-enriched amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men.

Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle.

Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids

Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle

Muscle Protein Anabolic Resistance to Essential Amino Acids Does Not Occur in Healthy Older Adults Before or After Resistance Exercise Training.

Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise.

Muscle protein metabolism responds similarly to exogenous amino acids in healthy younger and older adults during NO-induced hyperemia.

Muscle tissue changes with aging

Novel noninvasive breath test method for screening individuals at risk for diabetes.

Nutrition and sarcopenia of ageing.

PAX7+ satellite cells in young and older adults following resistance exercise

Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women

Post-absorptive muscle protein turnover affects resistance training hypertrophy.

Postexercise protein metabolism in older and younger men following moderate-intensity aerobic exercise.

Protein Requirements in Critically Ill Older Adults.

Protein Supplementation Does Not Affect Myogenic Adaptations to Resistance Training.

Protein Supplementation Has Minimal Effects on Muscle Adaptations during Resistance Exercise Training in Young Men: A Double-Blind Randomized Clinical Trial

Protein intake and muscle function in older adults

Protein metabolism in women and men: similarities and disparities.

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling

Quantification of muscle triglyceride synthesis rate requires an adjustment for total triglyceride content

Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle

Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle.

Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery.

Sequential muscle biopsies during a 6-h tracer infusion do not affect human mixed muscle protein synthesis and muscle phenylalanine kinetics.

Sex-dependent difference in the relationship between adipose-tissue cholesterol efflux and estradiol concentrations in young healthy humans

Short-term insulin and nutritional energy provision do not stimulate muscle protein synthesis if blood amino acid availability decreases

Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.

Soy-Dairy Protein Blend or Whey Protein Isolate Ingestion Induces Similar Postexercise Muscle Mechanistic Target of Rapamycin Complex 1 Signaling and Protein Synthesis Responses in Older Men.

Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle.

Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism.

Testing the effects of narrative and play on physical activity among breast cancer survivors using mobile apps: study protocol for a randomized controlled trial

The impact of postexercise essential amino acid ingestion on the ubiquitin proteasome and autophagosomal-lysosomal systems in skeletal muscle of older men.

The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly.

Vitamin D and endothelial vasodilation in older individuals: data from the PIVUS study

Whey Protein Hydrolysate Increases Amino Acid Uptake, mTORC1 Signaling, and Protein Synthesis in Skeletal Muscle of Healthy Young Men in a Randomized Crossover Trial