List of works by Chiara Dalla Man

12-Week 24/7 Ambulatory Artificial Pancreas With Weekly Adaptation of Insulin Delivery Settings: Effect on Hemoglobin A1c and Hypoglycemia

scientific article published on 13 October 2017

A Model for the Estimation of Hepatic Insulin Extraction After a Meal

scientific article published on 4 December 2015

A common variant in the MTNR1b gene is associated with increased risk of impaired fasting glucose (IFG) in youth with obesity

scientific article published on May 2015

A concerted decline in insulin secretion and action occurs across the spectrum of fasting and postchallenge glucose concentrations

scientific article published on February 2012

A dynamic risk measure from continuous glucose monitoring data

scientific article

A model of GLP-1 action on insulin secretion in nondiabetic subjects

scientific article

A model of glucose production during a meal

scientific article published in January 2006

A novel natural tracer method to measure complex carbohydrate metabolism

scientific article published on 02 July 2019

A software interface for in silico testing of type 2 diabetes treatments

scientific article published on 24 June 2022

A system model of oral glucose absorption: validation on gold standard data

scientific article

Acute inhibition of lipolysis does not affect postprandial suppression of endogenous glucose production

scientific article published on 5 July 2005

Adjustment of Open-Loop Settings to Improve Closed-Loop Results in Type 1 Diabetes: A Multicenter Randomized Trial

scientific article

Advancing our understanding of the glucose system via modeling: a perspective

scientific article published on May 2014

Age‐Related Changes in Insulin Sensitivity and β‐Cell Function Among European‐American and African‐American Women ⬇️

scientific article published on September 30, 2010

Alterations in postprandial hepatic glycogen metabolism in type 2 diabetes

scientific article published in December 2004

An index of parameter reproducibility accounting for estimation uncertainty: theory and case study on β-cell responsivity and insulin sensitivity

scientific article published on 7 April 2015

Assessment of beta-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests

scientific article published on 6 March 2007

Assessment of blood glucose predictors: the prediction-error grid analysis

scientific article

Assessment of postprandial glucose metabolism: conventional dual- vs. triple-tracer method

scientific article published on 23 May 2006

Assessment of pulsatile insulin secretion derived from peripheral plasma C-peptide concentrations by nonparametric stochastic deconvolution

scientific article published on 26 February 2019

Association between thyrotropin levels and insulin sensitivity in euthyroid obese adolescents

scientific article published on 7 April 2015

Cholecalciferol supplementation does not influence β-cell function and insulin action in obese adolescents: a prospective double-blind randomized trial

scientific article published on 17 December 2014

Circadian variability of insulin sensitivity: physiological input for in silico artificial pancreas

scientific article

Closed-loop artificial pancreas using subcutaneous glucose sensing and insulin delivery and a model predictive control algorithm: preliminary studies in Padova and Montpellier

scientific article published on September 2009

Co-occurrence of risk alleles in or near genes modulating insulin secretion predisposes obese youth to prediabetes

scientific article published on 23 September 2013

Common genetic variation in GLP1R and insulin secretion in response to exogenous GLP-1 in nondiabetic subjects: a pilot study ⬇️

scientific article

Contribution of endogenous glucagon-like peptide 1 to glucose metabolism after Roux-en-Y gastric bypass

scientific article published on 02 October 2013

Contribution of endogenous glucagon-like peptide-1 to changes in glucose metabolism and islet function in people with type 2 diabetes four weeks after Roux-en-Y gastric bypass (RYGB)

scientific article published on 23 December 2018

DHEA in elderly women and DHEA or testosterone in elderly men.

scientific article

Day and night closed-loop control in adults with type 1 diabetes: a comparison of two closed-loop algorithms driving continuous subcutaneous insulin infusion versus patient self-management

scientific article

Defects in GLP-1 response to an oral challenge do not play a significant role in the pathogenesis of prediabetes

scientific article published on 16 November 2011

Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training

scientific article published on 20 January 2015

Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1.

scientific article published on 28 March 2012

Diabetes-associated genetic variation in TCF7L2 alters pulsatile insulin secretion in humans

scientific article published on 09 April 2020

Diabetes: Models, Signals, and Control

scientific article

Differential effects of the circadian system and circadian misalignment on insulin sensitivity and insulin secretion in humans

scientific article published on 02 July 2018

Dipeptidyl peptidase-4 inhibition by vildagliptin and the effect on insulin secretion and action in response to meal ingestion in type 2 diabetes

scientific article published on 17 October 2008

Direct effects of exendin-(9,39) and GLP-1-(9,36)amide on insulin action, β-cell function, and glucose metabolism in nondiabetic subjects

scientific article published on April 2013

Diurnal pattern of insulin action in type 1 diabetes: implications for a closed-loop system

scientific article published on 27 February 2013

Diurnal pattern to insulin secretion and insulin action in healthy individuals

scientific article

Downregulation of the longevity-associated protein sirtuin 1 in insulin resistance and metabolic syndrome: potential biochemical mechanisms

scientific article

Dual glucagon-like peptide-1 receptor/glucagon receptor agonist SAR425899 improves beta-cell function in type 2 diabetes

scientific article published on 22 December 2019

Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men.

scientific article published on 11 May 2007

Effect of Pramlintide on Postprandial Glucose Fluxes in Type 1 Diabetes

scientific article published on March 2016

Effect of adding sitagliptin, a dipeptidyl peptidase-4 inhibitor, to metformin on 24-h glycaemic control and beta-cell function in patients with type 2 diabetes.

scientific article published in March 2007

Effects of age and sex on postprandial glucose metabolism: differences in glucose turnover, insulin secretion, insulin action, and hepatic insulin extraction

scientific article published in July 2006

Effects of delayed gastric emptying on postprandial glucose kinetics, insulin sensitivity, and β-cell function

scientific article published on 29 July 2014

Effects of nonglucose nutrients on insulin secretion and action in people with pre-diabetes

scientific article published in April 2007

Effects of the BET-inhibitor, RVX-208 on the HDL lipidome and glucose metabolism in individuals with prediabetes: A randomized controlled trial.

scientific article published on 8 March 2016

Effects of type 2 diabetes on insulin secretion, insulin action, glucose effectiveness, and postprandial glucose metabolism

scientific article published on 5 February 2009

Epicardial and pericardial fat in type 2 diabetes: favourable effects of biliopancreatic diversion

scientific article published in March 2015

Ethnic differences in insulin sensitivity, β-cell function, and hepatic extraction between Japanese and Caucasians: a minimal model analysis

scientific article published on 13 August 2014

Evaluating the efficacy of closed-loop glucose regulation via control-variability grid analysis

scientific article

Exercise effects on postprandial glucose metabolism in type 1 diabetes: a triple-tracer approach

scientific article published on 21 April 2015

Fully integrated artificial pancreas in type 1 diabetes: modular closed-loop glucose control maintains near normoglycemia

scientific article

GIM, simulation software of meal glucose-insulin model

scientific article published on May 2007

Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments

scientific article

Glucose fluxes during OGTT in adolescents assessed by a stable isotope triple tracer method

scientific article published in January 2008

Glucose metabolism during rotational shift-work in healthcare workers

scientific article published on 27 May 2017

Hepatic insulin sensitivity in healthy and prediabetic subjects: from a dual- to a single-tracer oral minimal model

scientific article published on 19 May 2015

Hyperglycemia But Not Hyperinsulinemia Is Favorable for Exercise in Type 1 Diabetes: A Pilot Study

scientific article published on 13 July 2020

Impaired Insulin Action Is Associated With Increased Glucagon Concentrations in Nondiabetic Humans

scientific article published on 6 November 2017

Impaired fasting glucose with or without impaired glucose tolerance: progressive or parallel states of prediabetes?

scientific article published on 3 June 2008

Impaired insulin signaling in unaffected siblings and patients with first-episode psychosis.

scientific article published on 9 March 2018

Improving Efficacy of Inhaled Technosphere Insulin (Afrezza) by Postmeal Dosing: In-silico Clinical Trial with the University of Virginia/Padova Type 1 Diabetes Simulator

scientific article

In silico design of optimal ratio for co-administration of pramlintide and insulin in type 1 diabetes

scientific article

In silico optimization of basal insulin infusion rate during exercise: implication for artificial pancreas

scientific article

In silico preclinical trials: a proof of concept in closed-loop control of type 1 diabetes

scientific article

Incorporating Long-Acting Insulin Glargine Into the UVA/Padova Type 1 Diabetes Simulator for In Silico Testing of MDI Therapies

scientific article published on 06 February 2019

Incorporation of inhaled insulin into the FDA accepted University of Virginia/Padova Type 1 Diabetes Simulator

scientific article

Increased Rates of Meal Absorption Do Not Explain Elevated 1-Hour Glucose in Subjects With Normal Glucose Tolerance

scientific article published on 21 November 2018

Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men.

scholarly article

Incretin action maintains insulin secretion, but not hepatic insulin action, in people with impaired fasting glucose

scientific article published on 13 August 2010

Insulin Sensitivity Index-Based Optimization of Insulin to Carbohydrate Ratio: In Silico Study Shows Efficacious Protection Against Hypoglycemic Events Caused by Suboptimal Therapy

scientific article published in February 2018

Insulin sensitivity by oral glucose minimal models: validation against clamp

scientific article published on 12 July 2005

Interstitial Fluid Glucose Is Not Just a Shifted-in-Time but a Distorted Mirror of Blood Glucose: Insight from an In Silico Study

scientific article published on 02 June 2016

Intranasal oxytocin fails to acutely improve glucose metabolism in obese men

scientific article published on 03 October 2018

Liver triacylglycerol content and gestational diabetes: effects of moderate energy restriction

scientific article published on 5 November 2016

Long-Term Outcomes of Biliopancreatic Diversion on Glycemic Control, Insulin Sensitivity and Beta Cell Function

scientific article

Meal simulation model of the glucose-insulin system

scientific article published in October 2007

Measurement of selective effect of insulin on glucose disposal from labeled glucose oral test minimal model

scientific article published on 21 June 2005

Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes

scientific article published on 27 November 2007

Mechanisms Underlying the Pathogenesis of Isolated Impaired Glucose Tolerance in Humans.

scientific article published on 7 September 2016

Mechanisms of hyperinsulinaemia in apparently healthy non-obese young adults: role of insulin secretion, clearance and action and associations with plasma amino acids

scientific article published on 06 September 2019

Mechanisms of the age-associated deterioration in glucose tolerance: contribution of alterations in insulin secretion, action, and clearance

scientific article published on July 2003

Metabolic and Genetic Determinants of Glucose Shape After Oral Challenge in Obese Youths: A Longitudinal Study

scientific article published on 01 February 2020

Minimal model estimation of glucose absorption and insulin sensitivity from oral test: validation with a tracer method

scientific article

Mixed meal simulation model of glucose-insulin system

scientific article published on January 2006

Model predictive control of type 1 diabetes: an in silico trial

scientific article

Model-Based Assessment of C-Peptide Secretion and Kinetics in Post Gastric Bypass Individuals Experiencing Postprandial Hyperinsulinemic Hypoglycemia

scientific article published on 15 March 2021

Model-Based Quantification of Glucagon-Like Peptide-1-Induced Potentiation of Insulin Secretion in Response to a Mixed Meal Challenge

scientific article

Modeling Plasma-to-Interstitium Glucose Kinetics from Multitracer Plasma and Microdialysis Data

scientific article published on 27 August 2015

Modeling Subcutaneous Absorption of Fast-Acting Insulin in Type 1 Diabetes

scientific article published on 15 December 2017

Modeling Subcutaneous Absorption of Long-Acting Insulin Glargine in Type 1 Diabetes

scientific article published on 28 May 2019

Modeling hepatic insulin sensitivity during a meal: validation against the euglycemic hyperinsulinemic clamp

scientific article published on 26 February 2013

Multicenter closed-loop insulin delivery study points to challenges for keeping blood glucose in a safe range by a control algorithm in adults and adolescents with type 1 diabetes from various sites.

scientific article

Multinational study of subcutaneous model-predictive closed-loop control in type 1 diabetes mellitus: summary of the results

scientific article

Multiscale modeling of insulin secretion.

scientific article published on 15 August 2011

Nocturnal Glucose Metabolism in Type 1 Diabetes: A Study Comparing Single Versus Dual Tracer Approaches

scientific article published on 29 June 2015

One-Day Bayesian Cloning of Type 1 Diabetes Subjects: Toward a Single-Day UVA/Padova Type 1 Diabetes Simulator

scientific article

Pathogenesis of pre-diabetes: mechanisms of fasting and postprandial hyperglycemia in people with impaired fasting glucose and/or impaired glucose tolerance

scientific article published in December 2006

Performance of individually-measured vs population-based C-peptide kinetics to assess β-cell function in presence and absence of acute insulin resistance.

scientific article published on September 2017

Physical activity into the meal glucose-insulin model of type 1 diabetes: in silico studies

scientific article

Physical activity measured by physical activity monitoring system correlates with glucose trends reconstructed from continuous glucose monitoring

scientific article published on 14 August 2013

Pioglitazone decreases fasting and postprandial endogenous glucose production in proportion to decrease in hepatic triglyceride content

scientific article published on 5 June 2008

Postprandial glucose fluxes and insulin sensitivity during exercise: a study in healthy individuals

scientific article published on 02 July 2013

Prediction of postprandial glycemic exposure: utility of fasting and 2-h glucose measurements alone and in combination with assessment of body composition, fitness, and strength

scientific article published in December 2006

Primary defects in beta-cell function further exacerbated by worsening of insulin resistance mark the development of impaired glucose tolerance in obese adolescents

scientific article published on 23 December 2008

Prospective evaluation of insulin and incretin dynamics in obese adults with and without diabetes for 2 years after Roux-en-Y gastric bypass.

scientific article published on 10 February 2018

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling

scientific article

Quantitative estimation of insulin sensitivity in type 1 diabetic subjects wearing a sensor-augmented insulin pump

scientific article published on 06 December 2013

Race differences in the association of oxidative stress with insulin sensitivity in African- and European-American women

scientific article published on 15 December 2011

Run-to-run tuning of model predictive control for type 1 diabetes subjects: in silico trial

scientific article

Six and 12 Weeks of Caloric Restriction Increases β Cell Function and Lowers Fasting and Postprandial Glucose Concentrations in People with Type 2 Diabetes

scientific article

Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of β-Cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series

scientific article published on 12 July 2016

TCF7L2 Genotype and α-Cell Function in Humans Without Diabetes

scientific article published on 2 November 2015

The UVA/PADOVA Type 1 Diabetes Simulator: New Features

scientific article

The UVA/Padova Type 1 Diabetes Simulator Goes From Single Meal to Single Day.

scientific article published in February 2018

The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose

scientific article

The effect of a bile acid sequestrant on glucose metabolism in subjects with type 2 diabetes

scientific article published on 18 December 2012

The effect of vagal nerve blockade using electrical impulses on glucose metabolism in nondiabetic subjects

scientific article

The effect of walking on postprandial glycemic excursion in patients with type 1 diabetes and healthy people

scientific article

The oral glucose minimal model: estimation of insulin sensitivity from a meal test

scientific article

The oral minimal model method

scientific article

The rs7903146 Variant in the TCF7L2 Gene Increases the Risk of Prediabetes/Type 2 Diabetes in Obese Adolescents by Impairing β-Cell Function and Hepatic Insulin Sensitivity

scientific article published on 13 June 2017

The university of Virginia/Padova type 1 diabetes simulator matches the glucose traces of a clinical trial.

scientific article

Three hours of intermittent hypoxia increases circulating glucose levels in healthy adults

scientific article published on 13 January 2017

Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women

scientific article published in March 2007

Two-hour seven-sample oral glucose tolerance test and meal protocol: minimal model assessment of beta-cell responsivity and insulin sensitivity in nondiabetic individuals

scientific article

Use of labeled oral minimal model to measure hepatic insulin sensitivity

scientific article published on 02 September 2008

beta-Cell function and insulin sensitivity in adolescents from an OGTT.

scientific article published on 4 December 2008

β-Cell function improvements in grade I/II obese subjects with type 2 diabetes 1 month after biliopancreatic diversion: results from modeling analyses of oral glucose tolerance tests and hyperglycemic clamp studies

scientific article published on 17 October 2013

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