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List of works by Mark L. Evans

5-HT obesity medication efficacy via POMC activation is maintained during aging

scientific article

5-HT2C receptor agonist anorectic efficacy potentiated by 5-HT1B receptor agonist coapplication: an effect mediated via increased proportion of pro-opiomelanocortin neurons activated

scientific article published on June 2013

A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial

scientific article published in April 2017

A new integrated care pathway for ambulance attended severe hypoglycaemia in the East of England: The Eastern Academic Health Science Network (EAHSN) model

scientific article published in September 2017

A parabrachial-hypothalamic cholecystokinin neurocircuit controls counterregulatory responses to hypoglycemia

scientific article

A randomized, multicentre trial evaluating the efficacy and safety of fast-acting insulin aspart in continuous subcutaneous insulin infusion in adults with type 1 diabetes (onset 5)

scientific article published on 13 January 2019

Accuracy of Continuous Glucose Monitoring During Three Closed-Loop Home Studies Under Free-Living Conditions

scientific article

Accuracy of subcutaneous continuous glucose monitoring in critically ill adults: improved sensor performance with enhanced calibrations

scientific article

Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats

scientific article published on November 2005

Acute Ingestion of Caffeinated Chewing Gum Improves Repeated Sprint Performance of Team Sports Athletes With Low Habitual Caffeine Consumption

scientific article

Alanine infusion during hypoglycaemia partly supports cognitive performance in healthy human subjects.

scientific article published in May 2004

Altered Hierarchy of Protective Responses Against Severe Hypoglycemia in Normal Aging in Healthy Men

article

An exploratory comparative study of volatile compounds in exhaled breath and emitted by skin using selected ion flow tube mass spectrometry

scientific article published in January 2008

Artificial pancreas: an emerging approach to treat Type 1 diabetes

scientific article published on July 2009

Assessing the effectiveness of 3 months day and night home closed-loop insulin delivery in adults with suboptimally controlled type 1 diabetes: a randomised crossover study protocol

scientific article

Assessing the effectiveness of a 3-month day-and-night home closed-loop control combined with pump suspend feature compared with sensor-augmented pump therapy in youths and adults with suboptimally controlled type 1 diabetes: a randomised parallel s

scientific article

Avoiding hypoglycaemia when treating type 1 diabetes

scientific article

BAD modulates counterregulatory responses to hypoglycemia and protective glucoprivic feeding

scientific article

Behavioral Patterns and Associations with Glucose Control During 12-Week Randomized Free-Living Clinical Trial of Day and Night Hybrid Closed-Loop Insulin Delivery in Adults with Type 1 Diabetes

scientific article published on 2 May 2017

Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome-results from a 6-month, double-blind, randomized controlled trial

scientific article published on 01 June 2019

Bolusing frequency and amount impacts glucose control during hybrid closed-loop

scientific article published on 29 July 2017

Brain control of insulin and glucagon secretion

scientific article published on 21 December 2012

Brain glucosamine boosts protective glucoprivic feeding

scientific article

Brain glucose sensing, glucokinase and neural control of metabolism and islet function

scientific article

Brain glucose sensors play a significant role in the regulation of pancreatic glucose-stimulated insulin secretion

scientific article published on 30 December 2011

Breath acetone concentration decreases with blood glucose concentration in type I diabetes mellitus patients during hypoglycaemic clamps

scientific article

Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel-group trial

scientific article

Closing the Loop in Adults, Children and Adolescents With Suboptimally Controlled Type 1 Diabetes Under Free Living Conditions: A Psychosocial Substudy

scientific article

Comment on Doyle et al. Closed-loop artificial pancreas systems: engineering the algorithms. Diabetes Care 2014;37:1191-1197.

scientific article published in October 2014

Comparison of Optimised MDI versus Pumps with or without Sensors in Severe Hypoglycaemia (the Hypo COMPaSS trial)

scientific article

Day and night closed-loop control in adults with type 1 diabetes: a comparison of two closed-loop algorithms driving continuous subcutaneous insulin infusion versus patient self-management

scientific article

Day and night home closed-loop insulin delivery in adults with type 1 diabetes: three-center randomized crossover study

scientific article published in July 2014

Day-and-night glycaemic control with closed-loop insulin delivery versus conventional insulin pump therapy in free-living adults with well controlled type 1 diabetes: an open-label, randomised, crossover study

scientific article published on 13 January 2017

Delay in onset of awareness of acute hypoglycemia and of restoration of cognitive performance during recovery

scientific article published on 01 July 2000

Distribution and neurochemical characterization of neurons within the nucleus of the solitary tract responsive to serotonin agonist-induced hypophagia

scientific article published on 13 August 2008

Distribution of cells responsive to 5-HT₆ receptor antagonist-induced hypophagia

scientific article published on 21 February 2014

Does insulin lispro preserve the physiological defences to hypoglycaemia during intensive insulin therapy with a conventional basal bolus regimen?

scientific article

Evaluating the Performance of a Novel Embedded Closed-loop System

scientific article published on 24 March 2014

Evaluating the accuracy and large inaccuracy of two continuous glucose monitoring systems

scientific article published on 20 December 2012

Evaluation of the cost effectiveness of exenatide versus insulin glargine in patients with sub-optimally controlled type 2 diabetes in the United Kingdom

scientific article published on 11 August 2008

Exhaled Breath Isoprene Rises During Hypoglycemia in Type 1 Diabetes

scientific article published in July 2016

Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes

scientific article published on 7 October 2015

Faster insulin action is associated with improved glycaemic outcomes during closed-loop insulin delivery and sensor-augmented pump therapy in adults with type 1 diabetes.

scientific article

Feasibility of closed-loop insulin delivery in type 2 diabetes: a randomized controlled study

scientific article published on 11 September 2013

Feasibility of fully automated closed-loop glucose control using continuous subcutaneous glucose measurements in critical illness: a randomized controlled trial.

scientific article

Glucokinase inhibitor glucosamine stimulates feeding and activates hypothalamic neuropeptide Y and orexin neurons

scientific article

Glucose turnover after replacement of usual therapy by insulin in insulin-naive type 2 diabetes subjects

scientific article

Holistic Impact of Closed-Loop Technology on People With Type 1 Diabetes

scientific article published on 7 April 2015

Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study

scientific article

Hypoglycaemia and glucose sensing

scientific article published in October 1997

Hypoglycaemia. Avoid 50% dextrose

scientific article published on 08 March 2011

Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses

scientific article published in October 2004

Hypothalamic glucose sensing and glycaemic disease

scientific article published on March 2011

Increased placental glucose transport rates in pregnant mice carrying fetuses with targeted disruption of their placental-specific Igf2 transcripts are not associated with raised circulating glucose concentrations

scientific article

Insulin pump therapy with automated insulin suspension in response to hypoglycemia: reduction in nocturnal hypoglycemia in those at greatest risk

scientific article

Intracerebroventricular Catalase Reduces Hepatic Insulin Sensitivity and Increases Responses to Hypoglycemia in Rats

scientific article published on 14 October 2016

Keto diets: good, bad or ugly?

scientific article published on 31 August 2018

Leptin does not directly affect CNS serotonin neurons to influence appetite.

scientific article published on May 2011

Life-threatening metabolic alkalosis in Pendred syndrome

scientific article

Lorcaserin improves glycemic control via a melanocortin neurocircuit

scientific article published on 21 July 2017

Low-Blood Glucose Avoidance Training Improves Glycemic Variability in Adults With Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia: HypoCOMPaSS Trial

scientific article published on 7 March 2016

Meta-analysis of overnight closed-loop randomized studies in children and adults with type 1 diabetes: the Cambridge cohort

scientific article published on November 2011

Neurochemical characterization of body weight-regulating leptin receptor neurons in the nucleus of the solitary tract

scientific article published on 6 August 2012

Neuropeptide Y cells represent a distinct glucose-sensing population in the lateral hypothalamus

scientific article published on 13 September 2011

Nutritional state influences Nociceptin/Orphanin FQ peptide receptor expression in the dorsal raphe nucleus

scientific article published on 16 September 2009

Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies

scientific article (publication date: 13 April 2011)

Pharmacokinetics of insulin aspart in pump-treated subjects with type 1 diabetes: reproducibility and effect of age, weight, and duration of diabetes

scientific article published on October 2013

Predicting risk of severe hypoglycaemia in type 2 diabetes

scientific article published on 21 March 2015

Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting

scientific article published on 20 February 2015

Raised late pregnancy glucose concentrations in mice carrying pups with targeted disruption of H19delta13

scientific article

Rapid Benefits of Structured Optimization and Sensor-Augmented Insulin Pump Therapy in Adults With Type 1 Diabetes

scientific article published on 21 June 2016

Recovery of hypoglycemia awareness in long-standing type 1 diabetes: a multicenter 2 × 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose self-monitoring (HypoCOMPaS

scientific article published on 22 May 2014

Recurrent hypoglycemia increases hypothalamic glucose phosphorylation activity in rats

scientific article

Recurrent hypoglycemia is associated with loss of activation in rat brain cingulate cortex

scientific article published on 6 March 2012

Reduced Counterregulation during Hypoglycemia with Raised Circulating Nonglucose Lipid Substrates: Evidence for Regional Differences in Metabolic Capacity in the Human Brain? ⬇️

scientific article published on August 1, 1998

Reduced insulin requirements during participation in the DAFNE (dose adjustment for normal eating) structured education programme

scientific article published on 26 January 2011

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial

scientific article

Response to comment on Little et al. Recovery of hypoglycemia awareness in long-standing type 1 diabetes: a multicenter 2 × 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventiona

scientific article published in December 2014

Restoration of self-awareness of hypoglycemia in adults with long-standing type 1 diabetes: hyperinsulinemic-hypoglycemic clamp substudy results from the HypoCOMPaSS trial

scientific article published on 15 October 2013

Reusable, robust, and accurate laser-generated photonic nanosensor.

scientific article

Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways

scientific article

Severe hypoglycaemia in type 1 diabetes mellitus: underlying drivers and potential strategies for successful prevention.

scientific article published on March 2014

Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons

scientific article published on 22 January 2016

Somatostatin receptor 5 and cannabinoid receptor 1 activation inhibit secretion of glucose-dependent insulinotropic polypeptide from intestinal K cells in rodents.

scientific article published on 8 August 2012

Successful use of acarbose to manage post-prandial glycaemia in two patients with type 1 diabetes on continuous subcutaneous insulin infusion

scientific article published on 01 December 2011

Targeting regulatory T cells with Interleukin-2 treatment in type 1 diabetes: a response-adaptive, non-randomised, open-label trial of repeat doses of Aldesleukin (DILfrequency)

The action profile of lispro is not blunted by mixing in the syringe with NPH insulin

scientific article published on 01 December 1998

The use of a portable breath analysis device in monitoring type 1 diabetes patients in a hypoglycaemic clamp: validation with SIFT-MS data.

scientific article

Too Much or Too Little? The Double Jeopardy of Subcutaneous Insulin Therapy in Diabetes

scientific article published on 01 October 2015

Unsupervised home use of an overnight closed-loop system over 3-4 weeks: a pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes.

scientific article published on 9 January 2015

Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes

scientific article published on February 2015

Use of fast-acting insulin aspart in insulin pump therapy in clinical practice

scientific article published on 19 June 2019

Validity of triple- and dual-tracer techniques to estimate glucose appearance.

scientific article

Variability of Insulin Requirements Over 12 Weeks of Closed-Loop Insulin Delivery in Adults With Type 1 Diabetes

scientific article published on 10 March 2016

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