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List of works by Christian Liedtke

A dual role of p21 in liver regeneration and hepatocarcinogenesis

scientific article published on 01 November 2008

A protective role of Stat3 in Fas mediated apoptosis of the liver

scientific article published on 01 May 2004

Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin

scientific article published on 13 May 2009

Alcohol and Hepatocellular Carcinoma: Adding Fuel to the Flame

scientific article published on 25 September 2017

Application of magnetic resonance imaging in transgenic and chemical mouse models of hepatocellular carcinoma

scientific article

CREB/PKA sensitive signalling pathways activate and maintain expression levels of the hepatitis B virus pre-S2/S promoter.

scientific article

Caspase 8 differentially controls hepatocytes and non-parenchymal liver cells during chronic cholestatic liver injury in mice

scientific article published on 6 August 2013

Caspase 8 small interfering RNA prevents acute liver failure in mice

scientific article

Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis.

scientific article

Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.

scientific article published on 18 December 2015

Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice

scientific article

Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice

scientific article published on 12 July 2012

Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice

scientific article published in April 2015

Dioxin increases C/EBPbeta transcription by activating cAMP/protein kinase A.

scientific article published on 18 December 2003

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease.

scientific article published on 11 November 2015

Experimental liver fibrosis research: update on animal models, legal issues and translational aspects

scientific article published on October 2013

Expression levels of the metalloproteinase ADAM8 critically regulate proliferation, migration and malignant signalling events in hepatoma cells

scientific article published on 13 December 2020

Expression of a cyclin E1 isoform in mice is correlated with the quiescent cell cycle status of hepatocytes in vivo

scientific article

Fatty acid binding receptors in intestinal physiology and pathophysiology

scientific article published on December 2010

Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury

scientific article published on 27 August 2014

Hepatic tissue environment in NEMO-deficient mice critically regulates positive selection of donor cells after hepatocyte transplantation

scientific article

Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents

scientific article published on 6 May 2013

Hepatocyte-specific NEMO deletion promotes NK/NKT cell- and TRAIL-dependent liver damage

scientific article published on 27 July 2009

Hepatocyte-specific inhibitor-of-kappaB-kinase deletion triggers the innate immune response and promotes earlier cell proliferation during liver regeneration

scientific article published in June 2008

Hepatocytes from embryonic stem cells: Prometheus revisited?

scientific article published on 01 March 2007

Human intestinal acyl-CoA synthetase 5 is sensitive to the inhibitor triacsin C.

scientific article published on November 2011

Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice.

scientific article published on 26 October 2017

Interferon-alpha enhances TRAIL-mediated apoptosis by up-regulating caspase-8 transcription in human hepatoma cells.

scientific article

Intestinal genetic inactivation of caspase-8 diminishes migration of enterocytes

scientific article

Is interleukin-6 a gender-specific risk factor for liver cancer?

scientific article published in October 2007

Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis

scientific article published on 13 September 2013

Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells

scientific article published in August 2002

Keratin 23 is a stress-inducible marker of mouse and human ductular reaction in liver disease

scientific article

Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model

scientific article

Lack of interleukin-6/glycoprotein 130/signal transducers and activators of transcription-3 signaling in hepatocytes predisposes to liver steatosis and injury in mice

scientific article published in February 2010

Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis.

scientific article published on 12 May 2010

Lipocalin-2 (LCN2) regulates PLIN5 expression and intracellular lipid droplet formation in the liver

scientific article published on 31 July 2014

Loss of Cyclin E1 attenuates hepatitis and hepatocarcinogenesis in a mouse model of chronic liver injury.

scientific article published on 19 March 2018

Loss of caspase-8 in hepatocytes accelerates the onset of liver regeneration in mice through premature nuclear factor kappa B activation.

scientific article

Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury

scientific article published on 28 August 2011

Mast Cells in Liver Fibrogenesis

scientific article published on 13 November 2019

Molecular cloning and sequence analysis of the Schizosaccharomyces pombe ade10+ gene.

scientific article published on October 1998

Molecular dissection of gp130-dependent pathways in hepatocytes during liver regeneration

scientific article

Molecular mechanism of Mitomycin C-dependent caspase-8 regulation: implications for apoptosis and synergism with interferon-alpha signalling

scientific article

NF-κB essential modifier is required for hepatocyte proliferation and the oval cell reaction after partial hepatectomy in mice.

scientific article

NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes

scientific article published on 14 February 2015

Notch inhibition counteracts Paneth cell death in absence of caspase-8

scientific article published on 16 May 2018

Origin of regenerating tubular cells after acute kidney injury

scientific article published on 13 January 2014

Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis

scientific journal article

Partial hepatectomy in mice

scientific article published in April 2015

Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis

scientific article published in May 2008

Pharmacological Inhibition of Cyclin-Dependent Kinases Triggers Anti-Fibrotic Effects in Hepatic Stellate Cells In Vitro

scientific article published on 05 May 2020

Pro-apoptotic Sorafenib signaling in murine hepatocytes depends on malignancy and is associated with PUMA expression in vitro and in vivo

scientific article published on 30 January 2014

Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes

scientific article published on 8 January 2013

Ras adenoviruses modulate cyclin E protein expression and DNA synthesis after partial hepatectomy.

scientific article

Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth.

scientific article

Sh(i)pping signals protect against Stat3-driven liver cancer

Silencing of caspase-8 in murine hepatocellular carcinomas is mediated via methylation of an essential promoter element

scientific article published on November 2005

TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.

scientific article published in May 2010

TLR2 and caspase-8 are essential for group B Streptococcus-induced apoptosis in microglia

scientific article

TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model

scientific article published on 9 August 2013

TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess

scientific article published on 28 November 2014

Targeting CCl4 -induced liver fibrosis by RNA interference-mediated inhibition of cyclin E1 in mice

scientific article published on 18 May 2017

Targeting Wnt Signaling via Notch in Intestinal Carcinogenesis

scientific article published on 18 April 2019

The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling.

scientific article published on 31 January 2014

The calcium-activated potassium channel KCa3.1 is an important modulator of hepatic injury

scientific article published on 29 June 2016

The carbon tetrachloride model in mice

scientific article published on April 2015

The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism

scientific article

The mating-type region of Schizosaccharomyces pombe contains an essential gene encoding a protein homologous to human modulators of HIV transactivation

scientific article published in August 1994

The role of JNK2 in toxic liver injury

scientific article

The role of TNF and Fas dependent signaling in animal models of inflammatory liver injury and liver cancer

scientific article published on 06 December 2011

When sleeping beauty wakes up and jumps into a cancer-minded environment

scientific article published on 01 June 2009

p21 ablation in liver enhances DNA damage, cholestasis, and carcinogenesis

scientific article published on 21 January 2015

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