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List of works by Edward J. Steele

A proposed reverse transcription mechanism for (CAG)n and similar expandable repeats that cause neurological and other diseases

scientific article published on 26 February 2020

ADAR deaminase A-to-I editing of DNA and RNA moieties of RNA:DNA hybrids has implications for the mechanism of Ig somatic hypermutation

scientific article published on 21 April 2017

Analysis of SARS-CoV-2 haplotypes and genomic sequences during 2020 in Victoria, Australia, in the context of putative deficits in innate immune deaminase anti-viral responses

scientific article published on 30 September 2021

Blood and saliva-derived exomes from healthy Caucasian subjects do not display overt evidence of somatic mosaicism

scientific article published on 18 May 2020

Cause of Cambrian Explosion - Terrestrial or Cosmic?

scientific article published on 12 March 2018

Cometary panspermia and origin of life?

scientific article published in 2020

Commentary: Past, present, and future of epigenetics applied to livestock breeding - Hard versus Soft Lamarckian Inheritance Mechanisms

scientific article published on 23 February 2016

Computational analyses show A-to-G mutations correlate with nascent mRNA hairpins at somatic hypermutation hotspots.

scientific article

Critical Analysis of Strand-Biased Somatic Mutation Signatures in TP53 versus Ig Genes, in Genome-Wide Data and the Etiology of Cancer

article

DNA polymerase-eta as a reverse transcriptase: implications for mechanisms of hypermutation in innate anti-retroviral defences and antibody SHM systems

scientific article published in July 2004

Experiments to prove continuing microbial ingress from Space to Earth

scientific article published in 2020

Genesis of ancestral haplotypes: RNA modifications and reverse transcription-mediated polymorphisms

scientific article published on 13 December 2010

Genesis of the strand-biased signature in somatic hypermutation of rearranged immunoglobulin variable genes

scientific article

Genetics of Marbling in Wagyu Revealed by the Melting Temperature of Intramuscular and Subcutaneous Lipids.

scientific article published on 23 October 2017

Genomic evolution in domestic cattle: Ancestral haplotypes and healthy beef ⬇️

scientific article published on February 19, 2011

Germline V repertoires: Origin, maintenance, diversification

scientific article published on 01 June 2018

Haplotypes for Type, Degree, and Rate of Marbling in Cattle Are Syntenic with Human Muscular Dystrophy

scientific article

Human DNA polymerase-eta, an A-T mutator in somatic hypermutation of rearranged immunoglobulin genes, is a reverse transcriptase

scientific article

Introduction—Panspermia, 2020

scientific article published on 07 July 2020

Lamarck and Panspermia - On the Efficient Spread of Living Systems Throughout the Cosmos

scientific article published on 22 August 2019

Mechanism of somatic hypermutation: critical analysis of strand biased mutation signatures at A:T and G:C base pairs

scientific article

Molecular evolution of V(H)9 germline genes isolated from DBA, BALB, 129 and C57BL mouse strains and sublines

scientific article published on 6 May 2003

Molecular model linking Th2 polarized M2 tumour-associated macrophages with deaminase-mediated cancer progression mutation signatures

scientific article published on 18 March 2019

Origin of new emergent Coronavirus and Candida fungal diseases—Terrestrial or cosmic?

scientific article published in 2020

Reflections on ancestral haplotypes: medical genomics, evolution, and human individuality

scientific article published on 01 January 2014

Reflections on the state of play in somatic hypermutation

scientific article published on 21 March 2008

Regulatory T cells and co-evolution of allele-specific MHC recognition by the TCR

scientific article published on 17 December 2019

Reply to editorial and commentaries on Steele, Al-Mufti, Augustyn, Chandrajith, Coghlan, Coulson et al. (2018) "Cause of Cambrian explosion - Terrestrial or Cosmic?"

scientific article published on 13 March 2018

Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory

scientific article published on 23 November 2017

Soma-to-germline feedback is implied by the extreme polymorphism at IGHV relative to MHC: The manifest polymorphism of the MHC appears greatly exceeded at Immunoglobulin loci, suggesting antigen-selected somatic V mutants penetrate Weismann's Barrie

scientific article

Somatic hypermutation and the discovery of A-to-I RNA editing sites?

scientific article published on 24 September 2011

Somatic hypermutation in immunity and cancer: Critical analysis of strand-biased and codon-context mutation signatures

scientific article

Somatic mutation patterns in non-lymphoid cancers resemble the strand biased somatic hypermutation spectra of antibody genes.

scientific article published on 24 April 2010

The boundaries of the distribution of somatic hypermutation of rearranged immunoglobulin variable genes

scientific article published on April 2004

The efficient Lamarckian spread of life in the cosmos

scientific article published in 2020

The sociology of science and generality of the DNA/RNA/protein paradigm throughout the cosmos

scientific article published in 2020

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