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List of works by Edward Boyden

3D nanofabrication by volumetric deposition and controlled shrinkage of patterned scaffolds

scientific article published on 01 December 2018

A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality

scientific article published on 01 July 2018

A direct-to-drive neural data acquisition system

scientific article

A fully genetically encoded protein architecture for optical control of peptide ligand concentration

scientific article

A gene-fusion strategy for stoichiometric and co-localized expression of light-gated membrane proteins.

scientific article published on 6 November 2011

A genetically encoded near-infrared fluorescent calcium ion indicator

A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex

scientific article

A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters

scientific article published on 26 February 2018

A theoretical analysis of single molecule protein sequencing via weak binding spectra

scientific article published on 28 March 2019

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

scientific article published on 25 March 2012

A wirelessly powered and controlled device for optical neural control of freely-behaving animals

scientific article

Activation of specific interneurons improves V1 feature selectivity and visual perception

scientific article

Advances in the automation of whole-cell patch clamp technology

scientific article published on 20 July 2019

All-Optical Electrophysiology Reveals the Role of Lateral Inhibition in Sensory Processing in Cortical Layer 1

scientific article published on 23 January 2020

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

scientific article

An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques

scientific article published on 14 April 2020

An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques

scientific article published on 01 July 2020

Architecting Discovery: A Model for How Engineers Can Help Invent Tools for Neuroscience

scientific article published on 01 May 2019

Assembly and operation of the autopatcher for automated intracellular neural recording in vivo.

scientific article

Author Correction: Gamma frequency entrainment attenuates amyloid load and modifies microglia

scientific article published in Nature

Automated Assessment of Loss of Consciousness Using Whisker And Paw Movements During Anesthetic Dosing in Head-Fixed Rodents

scientific article published on 01 July 2018

Automated in vivo patch clamp evaluation of extracellular multielectrode array spike recording capability

scientific article published on 11 July 2018

Automated scalable segmentation of neurons from multispectral images ⬇️

scientific article published in January 2016

Automated whole-cell patch-clamp electrophysiology of neurons in vivo

scientific article

Automated, in-vivo, whole-cell electrophysiology using an integrated patch-clamp amplifier

scientific article published on 8 July 2013

Autonomous patch-clamp robot for functional characterization of neurons in vivo: development and application to mouse visual cortex

scientific article published on 10 April 2019

Cell diversity and network dynamics in photosensitive human brain organoids.

scientific article published on 26 April 2017

Cerebellum-dependent learning: the role of multiple plasticity mechanisms

scientific article

Channelrhodopsin-2 and optical control of excitable cells

scientific article

Characterization of the functional MRI response temporal linearity via optical control of neocortical pyramidal neurons

scientific article

Close-Packed Silicon Microelectrodes for Scalable Spatially Oversampled Neural Recording

scientific article

Closed-Loop Real-Time Imaging Enables Fully Automated Cell-Targeted Patch-Clamp Neural Recording In Vivo

scientific article published on September 2017

Closed-Loop Real-Time Imaging Enables Fully Automated Cell-Targeted Patch-Clamp Neural Recording In Vivo

scientific article published in August 2017

Closed-loop, ultraprecise, automated craniotomies

scientific article published on 8 April 2015

Cortical column and whole-brain imaging with molecular contrast and nanoscale resolution.

scientific article published on 01 January 2019

DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase

scientific article

Distinct patterns of stimulus generalization of increases and decreases in VOR gain

scientific article published on 20 July 2005

Dopamine Neuron-Specific Optogenetic Stimulation in Rhesus Macaques

scientific article published on September 2016

Drug discovery: a jump-start for electroceuticals

scientific article

Ed Boyden: A light switch for neurons

TED2011

Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation.

scientific article published on 19 May 2017

Erratum: Corrigendum: Independent optical excitation of distinct neural populations

scholarly article published in Nature Methods

Evidence for long-timescale patterns of synaptic inputs in CA1 of awake behaving mice.

scientific article published on 26 December 2017

Expansion Microscopy for Beginners: Visualizing Microtubules in Expanded Cultured HeLa Cells

scientific article published on 01 June 2020

Expansion Microscopy: Protocols for Imaging Proteins and RNA in Cells and Tissues.

scientific article published on 02 August 2018

Expansion Mini-Microscopy: An Enabling Alternative in Point-of-Care Diagnostics

scientific article published on 22 March 2017

Expansion microscopy of C. elegans

scientific article published on 01 May 2020

Expansion microscopy of zebrafish for neuroscience and developmental biology studies.

scientific article published on 21 November 2017

Expansion microscopy: principles and uses in biological research

FEF inactivation with improved optogenetic methods

scientific article

Face-selective electrostatic control of hydrothermal zinc oxide nanowire synthesis

scientific article

Fast-conducting mechanoreceptors contribute to withdrawal behavior in normal and nerve injured rats

scientific article

Feasibility of 3D Reconstruction of Neural Morphology Using Expansion Microscopy and Barcode-Guided Agglomeration.

scientific article published on 24 October 2017

Functional and topological diversity of LOV domain photoreceptors

scientific article published on 29 February 2016

Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection

scientific article published on 07 May 2019

Gamma frequency entrainment attenuates amyloid load and modifies microglia

scientific article published on December 2016

Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy

scientific article published on 16 November 2017

Green fluorescent genetically encoded calcium indicator based on calmodulin/M13-peptide from fungi

scientific article published on 24 August 2017

Hearing the light: neural and perceptual encoding of optogenetic stimulation in the central auditory pathway

scientific article

Hebbian and neuromodulatory mechanisms interact to trigger associative memory formation

scientific article

Heterogeneous neural amplifier integration for scalable extracellular microelectrodes

scientific article published on August 2016

High-performance genetically targetable optical neural silencing by light-driven proton pumps

scientific article

High-resolution mapping of DNA polymerase fidelity using nucleotide imbalances and next-generation sequencing.

scientific article published in July 2018

Hybrid Microscopy: Enabling Inexpensive High-Performance Imaging through Combined Physical and Optical Magnifications

scientific article published on 15 March 2016

Imaging cellular ultrastructures using expansion microscopy (U-ExM)

scientific article published on 17 December 2018

Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues

scientific article published on 19 August 2019

Improved genetically encoded near-infrared fluorescent calcium ion indicators for in vivo imaging

scientific article published on 24 November 2020

In situ genome sequencing resolves DNA sequence and structure in intact biological samples

scientific article published on 31 December 2020

In vivo robotics: the automation of neuroscience and other intact-system biological fields.

scientific article published on 10 July 2013

Independent control of gamma and theta activity by distinct interneuron networks in the olfactory bulb

scientific article

Independent optical excitation of distinct neural populations

scientific article

Influenza virus exploits tunneling nanotubes for cell-to-cell spread

scientific article

Informational lesions: optical perturbation of spike timing and neural synchrony via microbial opsin gene fusions

scientific article published on 27 August 2009

Integrated Neurophotonics: Toward Dense Volumetric Interrogation of Brain Circuit Activity-at Depth and in Real Time

scientific article published on 01 October 2020

Integration of autopatching with automated pipette and cell detection in vitro

scientific article

Investigating the feasibility of channelrhodopsin variants for nanoscale optogenetics

scientific article published on 01 January 2019

Iterative expansion microscopy

scientific article published on 17 April 2017

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates

scientific article published on 3 October 2017

Light microscopy based approach for mapping connectivity with molecular specificity

scientific article published on 15 September 2020

Light sheet theta microscopy for rapid high-resolution imaging of large biological samples.

scientific article published on 29 May 2018

Measuring cation dependent DNA polymerase fidelity landscapes by deep sequencing

scientific article published in 2012

Melanopsin for precise optogenetic activation of astrocyte-neuron networks

scientific article published on 11 January 2019

Mesoscale-duration activated states gate spiking in response to fast rises in membrane voltage in the awake brain

scientific article published on 31 May 2017

Microchip amplifier for in vitro, in vivo, and automated whole cell patch-clamp recording.

scientific article

Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain

scientific article

Millisecond-timescale, genetically targeted optical control of neural activity

scientific article (publication date: September 2005)

Minimal Size of Cell Assemblies Coordinated by Gamma Oscillations ⬇️

scientific article published on February 9, 2012

Modulation of nitrogen vacancy charge state and fluorescence in nanodiamonds using electrochemical potential

scientific article published on 24 March 2016

Multi-neuron intracellular recording in vivo via interacting autopatching robots.

scientific article published on 3 January 2018

Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition

scientific article published on 14 March 2019

Multidimensional screening yields channelrhodopsin variants having improved photocurrent and order-of-magnitude reductions in calcium and proton currents

scientific article published on 04 January 2019

Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution

scientific article

Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes

scientific article published on 26 September 2019

Multiplexed neural recording along a single optical fiber via optical reflectometry

scientific article published in May 2016

Multiwaveguide implantable probe for light delivery to sets of distributed brain targets ⬇️

scientific article published on December 15, 2010

Nanoscale imaging of RNA with expansion microscopy

scientific article published on 04 July 2016

Nanoscale imaging of clinical specimens using conventional and rapid-expansion pathology

scientific article published on 01 April 2020

Nanoscale imaging of clinical specimens using pathology-optimized expansion microscopy.

scientific article published on 17 July 2017

Nanotools for neuroscience and brain activity mapping

scientific article published on 20 March 2013

Near-Infrared Fluorescent Proteins Engineered from Bacterial Phytochromes in Neuroimaging

scientific article published on 7 October 2017

Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields

scientific article (publication date: June 2017)

Noninvasive optical inhibition with a red-shifted microbial rhodopsin

scientific article published on 6 July 2014

Novel Genetically Encoded Bright Positive Calcium Indicator NCaMP7 Based on the mNeonGreen Fluorescent Protein

scientific article published on 28 February 2020

Nucleotide-time alignment for molecular recorders

scientific article

Optical imaging. Expansion microscopy

scientific article

Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia

scientific article published on 24 October 2016

Optogenetic astrocyte activation modulates response selectivity of visual cortex neurons in vivo

scientific article

Optogenetic inactivation modifies monkey visuomotor behavior

scientific article

Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement

scientific article

Optogenetic stimulation of the cochlear nucleus using channelrhodopsin-2 evokes activity in the central auditory pathways

scientific article

Optogenetic tools for analyzing the neural circuits of behavior ⬇️

scientific article published on November 4, 2011

Oxytocin-dependent reopening of a social reward learning critical period with MDMA.

scientific article published on 3 April 2019

PatcherBot: a single-cell electrophysiology robot for adherent cells and brain slices

scientific article published on 10 April 2019

Physical principles for scalable neural recording.

scientific article

Physiology. Synthetic physiology

scientific article published on June 2011

Population imaging of neural activity in awake behaving mice

scientific article published on 09 October 2019

Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator

scientific article published on 25 June 2020

Principles of designing interpretable optogenetic behavior experiments.

scientific article

Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics

scientific article published on 12 September 2019

Processes for design, construction and utilisation of arrays of light-emitting diodes and light-emitting diode-coupled optical fibres for multi-site brain light delivery

scientific article

Prosthetic systems for therapeutic optical activation and silencing of genetically-targeted neurons

scientific article published on January 2008

Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies

scientific article published on 04 July 2016

Publisher Correction: A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters.

scientific article published on 8 March 2018

Publisher Correction: Temporally precise single-cell-resolution optogenetics

scientific article published on 01 June 2018

Q&A: Expansion microscopy

scientific article

RNA timestamps identify the age of single molecules in RNA sequencing

scientific article published on 19 October 2020

Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues

scientific article published on 21 September 2017

Scalable fluidic injector arrays for viral targeting of intact 3-D brain circuits

scientific article published on 21 January 2010

Scalable, Modular Three-Dimensional Silicon Microelectrode Assembly via Electroless Plating

scientific article published on 30 August 2018

Selective engagement of plasticity mechanisms for motor memory storage.

scientific article published in September 2006

Silencing cortical activity during sound-localization training impairs auditory perceptual learning

scientific article published on 12 July 2019

Simple precision creation of digitally specified, spatially heterogeneous, engineered tissue architectures

scientific article

Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy

scientific article

Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics

scientific article published on 17 November 2020

Spatial information in large-scale neural recordings

scientific article published on January 2014

Statistical analysis of molecular signal recording

scientific article (publication date: 2013)

Stress Enables Reinforcement-Elicited Serotonergic Consolidation of Fear Memory

scientific article

Striosome-dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons

scientific article published on 19 September 2016

Submillisecond Optogenetic Control of Neuronal Firing with Two-Photon Holographic Photoactivation of Chronos.

scientific article published on 2 October 2017

Superior temporal resolution of Chronos versus channelrhodopsin-2 in an optogenetic model of the auditory brainstem implant

scientific article

Synthetic physiology strategies for adapting tools from nature for genetically targeted control of fast biological processes.

scientific article published on January 2011

Temporally precise single-cell-resolution optogenetics

scientific article published on 13 November 2017

The promise of organ and tissue preservation to transform medicine

scientific article published on June 2017

Three-dimensional multiwaveguide probe array for light delivery to distributed brain circuits ⬇️

scientific article published on December 1, 2012

Toward the second generation of optogenetic tools

scientific article

Towards optogenetic sensory replacement.

scientific article

Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance

scientific article

Transient optogenetic inactivation of the medial entorhinal cortex biases the active population of hippocampal neurons

scientific article

Translating Temporal Interference Brain Stimulation to Treat Neurological and Psychiatric Conditions

scientific article published on 01 November 2018

Virally delivered Channelrhodopsin-2 Safely and Effectively Restores Visual Function in Multiple Mouse Models of Blindness ⬇️

scientific article published on April 19, 2011

Voices in methods development

scientific article published on 01 October 2019

Wide-field three-photon excitation in biological samples

scientific article published in May 2017

Young adult born neurons enhance hippocampal dependent performance via influences on bilateral networks

scientific article published on 03 December 2016

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