List of works - Johan Hartman

A Zebrafish Model Discovers a Novel Mechanism of Stromal Fibroblast-Mediated Cancer Metastasis

scientific article published on 18 April 2017

AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.

scientific article published on August 2014

An Open-Source, Automated Tumor-Infiltrating Lymphocyte Algorithm for Prognosis in Triple-Negative Breast Cancer

scientific article published in 2021

Artificial intelligence as the next step towards precision pathology

scientific article published on 03 March 2020

CETSA-based target engagement of taxanes as biomarkers for efficacy and resistance

scientific article published on 18 December 2019

CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples

scientific article published on 18 October 2019

Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression.

scientific article published on 18 June 2012

Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers

scientific article published on 27 July 2020

Current concepts and significance of estrogen receptor β in prostate cancer ⬇️

scientific article published on July 20, 2012

Differential expression of sex hormone receptors in abdominal aortic aneurysms.

scientific article published on 11 November 2016

Digital image analysis in breast pathology-from image processing techniques to artificial intelligence.

scientific article published on 7 November 2017

Digital image analysis of Ki67 in hot spots is superior to both manual Ki67 and mitotic counts in breast cancer

scientific article

Digital image analysis outperforms manual biomarker assessment in breast cancer.

scientific article

ERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer

scientific article

Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.

scientific article

Estrogen receptors in colorectal cancer: goalkeepers, strikers, or bystanders?

scientific article published on 27 July 2010

Estrogen receptors β1 and β2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3.

scientific article

Evidence of a functional estrogen receptor in parathyroid adenomas.

scientific article

Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes.

scientific article

Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs).

scientific article published on 12 February 2018

FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistance

scientific article

FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer

scientific article

Gene protein detection platform--a comparison of a new human epidermal growth factor receptor 2 assay with conventional immunohistochemistry and fluorescence in situ hybridization platforms.

scientific article

Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages.

scientific article

Hes-6, an inhibitor of Hes-1, is regulated by 17beta-estradiol and promotes breast cancer cell proliferation

scientific article

High prevalence of human cytomegalovirus proteins and nucleic acids in primary breast cancer and metastatic sentinel lymph nodes

scientific article

Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling.

scientific article published on 29 November 2017

Low concordance of biomarkers in histopathological and cytological material from breast cancer.

scientific article

Lymphoid aggregates in Crohn's colitis and mucosal immunity

scientific article published on 25 August 2013

Next generation pathology: artificial intelligence enhances histopathology practice

scientific article published on 23 October 2019

Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development

scientific article

Oestrogen receptors β1 and βcx have divergent roles in breast cancer survival and lymph node metastasis

scientific article

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer

scientific article published on 09 August 2019

Pericyte-fibroblast transition promotes tumor growth and metastasis.

scientific article published on 07 September 2016

Prognostic value of Ki67 analysed by cytology or histology in primary breast cancer

scientific article published on 27 March 2018

Publisher Correction: Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

scientific article published on 01 January 2018

Response to correspondence on ‘Low concordance of biomarkers in histopathological and cytological material from breast cancer’

Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease

scientific article published on 08 May 2019

Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells

scientific article published on 21 August 2015

Sequencing of breast cancer stem cell populations indicates a dynamic conversion between differentiation states in vivo

scientific article

Sequencing-based breast cancer diagnostics as an alternative to routine biomarkers

scientific article

Spatial transcriptomics of B cell and T cell receptors reveals lymphocyte clonal dynamics

scientific article published on 07 December 2023

Superficial scrapings from breast tumors is a source for biobanking and research purposes.

scientific article

The dyslexia candidate gene DYX1C1 is a potential marker of poor survival in breast cancer

scientific article

Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds

scientific article published on 04 February 2020

Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies

scientific article published on 29 June 2020

Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells

scientific article published on 27 May 2016

Tumour nuclear oestrogen receptor beta 1 correlates inversely with parathyroid tumour weight

scientific article

Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

article

mTOR inhibitors counteract tamoxifen-induced activation of breast cancer stem cells.

scientific article

miR-206 inhibits cell migration through direct targeting of the actin-binding protein coronin 1C in triple-negative breast cancer

scientific article

List of works by Johan Hartman

A Zebrafish Model Discovers a Novel Mechanism of Stromal Fibroblast-Mediated Cancer Metastasis

AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.

An Open-Source, Automated Tumor-Infiltrating Lymphocyte Algorithm for Prognosis in Triple-Negative Breast Cancer

Artificial intelligence as the next step towards precision pathology

CETSA-based target engagement of taxanes as biomarkers for efficacy and resistance

CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples

Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression.

Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers

Current concepts and significance of estrogen receptor β in prostate cancer ⬇️

Differential expression of sex hormone receptors in abdominal aortic aneurysms.

Digital image analysis in breast pathology-from image processing techniques to artificial intelligence.

Digital image analysis of Ki67 in hot spots is superior to both manual Ki67 and mitotic counts in breast cancer

Digital image analysis outperforms manual biomarker assessment in breast cancer.

ERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer

Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.

Estrogen receptors in colorectal cancer: goalkeepers, strikers, or bystanders?

Estrogen receptors β1 and β2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3.

Evidence of a functional estrogen receptor in parathyroid adenomas.

Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes.

Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs).

FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistance

FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer

Gene protein detection platform--a comparison of a new human epidermal growth factor receptor 2 assay with conventional immunohistochemistry and fluorescence in situ hybridization platforms.

Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages.

Hes-6, an inhibitor of Hes-1, is regulated by 17beta-estradiol and promotes breast cancer cell proliferation

High prevalence of human cytomegalovirus proteins and nucleic acids in primary breast cancer and metastatic sentinel lymph nodes

Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling.

Low concordance of biomarkers in histopathological and cytological material from breast cancer.

Lymphoid aggregates in Crohn's colitis and mucosal immunity

Next generation pathology: artificial intelligence enhances histopathology practice

Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development

Oestrogen receptors β1 and βcx have divergent roles in breast cancer survival and lymph node metastasis

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer

Pericyte-fibroblast transition promotes tumor growth and metastasis.

Prognostic value of Ki67 analysed by cytology or histology in primary breast cancer

Publisher Correction: Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

Response to correspondence on ‘Low concordance of biomarkers in histopathological and cytological material from breast cancer’

Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease

Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells

Sequencing of breast cancer stem cell populations indicates a dynamic conversion between differentiation states in vivo

Sequencing-based breast cancer diagnostics as an alternative to routine biomarkers

Spatial transcriptomics of B cell and T cell receptors reveals lymphocyte clonal dynamics

Superficial scrapings from breast tumors is a source for biobanking and research purposes.

The dyslexia candidate gene DYX1C1 is a potential marker of poor survival in breast cancer

Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds

Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies

Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells

Tumour nuclear oestrogen receptor beta 1 correlates inversely with parathyroid tumour weight

Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

mTOR inhibitors counteract tamoxifen-induced activation of breast cancer stem cells.

miR-206 inhibits cell migration through direct targeting of the actin-binding protein coronin 1C in triple-negative breast cancer