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List of works by Robert K. Shepherd

A fully implantable rodent neural stimulator

scientific article

A fully implantable stimulator for use in small laboratory animals

scientific article

A multichannel scala tympani electrode array incorporating a drug delivery system for chronic intracochlear infusion.

scientific article published in October 2002

A partial hearing animal model for chronic electro-acoustic stimulation.

scientific article

ATP-induced photoreceptor death in a feline model of retinal degeneration

scientific article published on 25 November 2014

Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling.

scientific article

An automated system for rapid evaluation of high-density electrode arrays in neural prostheses.

scientific article published on 15 April 2011

An improved cochlear implant electrode array for use in experimental studies

scientific article

An in vitro model for investigating impedance changes with cell growth and electrical stimulation: implications for cochlear implants

scientific article published on 2 December 2004

Assessment of the protective effect of pneumococcal vaccination in preventing meningitis after cochlear implantation

scientific article

Basis of electrical stimulation of the cochlea and the cochlear nucleus.

scientific article published on January 2006

Bilateral cochlear implantation in the ferret: a novel animal model for behavioral studies.

scientific article

Can we prevent cochlear implant recipients from developing pneumococcal meningitis?

scientific article

Challenges for stem cells to functionally repair the damaged auditory nerve

scientific article

Changes in biphasic electrode impedance with protein adsorption and cell growth

scientific article

Chronic Electrical Stimulation of the Auditory Nerve in Cats

Chronic depolarization enhances the trophic effects of brain-derived neurotrophic factor in rescuing auditory neurons following a sensorineural hearing loss.

scientific article

Chronic electrical stimulation of the auditory nerve at high stimulus rates: a physiological and histopathological study

scientific article published on March 1997

Chronic electrical stimulation of the auditory nerve using non-charge-balanced stimuli.

scientific article published in January 1999

Chronic electrical stimulation with a suprachoroidal retinal prosthesis: a preclinical safety and efficacy study

scientific article (publication date: 2014)

Chronic intracochlear electrical stimulation at high charge densities results in platinum dissolution but not neural loss or functional changes in vivo

scientific article published on 05 December 2018

Chronic intracochlear electrical stimulation at high charge densities: Reducing platinum dissolution

scientific article published on 11 September 2020

Chronic neurotrophin delivery promotes ectopic neurite growth from the spiral ganglion of deafened cochleae without compromising the spatial selectivity of cochlear implants.

scientific article

Chronic placental insufficiency has long-term effects on auditory function in the guinea pig.

scientific article published in April 2002

Clinical application of neurotrophic factors: the potential for primary auditory neuron protection

scientific article

Clinical findings for a group of infants and young children with auditory neuropathy.

scientific article

Cochlear Implantation in Children: Labyrinthitis following Pneumococcal Otitis Media in Unimplanted and Implanted Cat Cochleas

article

Cochlear immunochemistry--a new technique based on gelatin embedding

scientific article published in October 2003

Cochlear implant use following neonatal deafness influences the cochleotopic organization of the primary auditory cortex in cats

scientific article

Cochlear implantation for chronic electrical stimulation in the mouse.

scientific article published on 18 September 2013

Cochlear implantation in rats: a new surgical approach.

scientific article

Cochlear implants and brain plasticity

scientific article

Cochlear implants stimulate activity-dependent CREB pathway in the deaf auditory cortex: implications for molecular plasticity induced by neural prosthetic devices

scientific article

Cochlear pathology following chronic electrical stimulation of the auditory nerve. I: Normal hearing kittens

scientific article published in September 1992

Cochlear pathology following chronic electrical stimulation of the auditory nerve: II. Deafened kittens.

scientific article published on December 1994

Cochlear pathology following chronic electrical stimulation using non charge balanced stimuli.

scientific article published in January 1991

Cochleotopic selectivity of a multichannel scala tympani electrode array using the 2-deoxyglucose technique

scientific article published in May 1992

Concise review: the potential of stem cells for auditory neuron generation and replacement.

scientific article published on 26 July 2007

Cortical activation following chronic passive implantation of a wide-field suprachoroidal retinal prosthesis

scientific article published on 26 June 2014

Deafness-induced changes in the auditory pathway: implications for cochlear implants

scientific article

Development of a cell-based treatment for long-term neurotrophin expression and spiral ganglion neuron survival

scientific article published in August 2014

Development of a surgical approach for a wide-view suprachoroidal retinal prosthesis: evaluation of implantation trauma

scientific article published on 27 August 2011

Development of a surgical procedure for implantation of a prototype suprachoroidal retinal prosthesis

scientific article

Development of hearing and vocalization in a marsupial, the Northern Quoll, Dasyurus hallucatus

scientific article published in December 1996

Distortion product otoacoustic emission and auditory brainstem responses in the echidna (Tachyglossus aculeatus).

scientific article

Effect of chronic electrical stimulation on cochlear nucleus neuron size in normal hearing kittens

scientific article

Effect of interphase gap and pulse duration on electrically evoked potentials is correlated with auditory nerve survival.

scientific article published on 27 April 2006

Effects of chronic cochlear electrical stimulation after an extended period of profound deafness on primary auditory cortex organization in cats

scientific article published on 10 December 2013

Effects of chronic electrical stimulation on spiral ganglion neuron survival and size in deafened kittens

scientific article published on May 1998

Effects of deafness and cochlear implant use on temporal response characteristics in cat primary auditory cortex

scientific article published on 14 June 2014

Effects of inner ear trauma on the risk of pneumococcal meningitis

scientific article

Effects of localized neurotrophin gene expression on spiral ganglion neuron resprouting in the deafened cochlea

scientific article

Effects of neonatal partial deafness and chronic intracochlear electrical stimulation on auditory and electrical response characteristics in primary auditory cortex

scientific article

Electrical stimulation causes rapid changes in electrode impedance of cell-covered electrodes.

scientific article

Electrical stimulation of the auditory nerve in deaf kittens: effects on cochlear nucleus morphology

scientific article published in November 1991

Electrical stimulation of the auditory nerve. I. Correlation of physiological responses with cochlear status.

scientific article published in June 1997

Electrical stimulation of the auditory nerve. III. Response initiation sites and temporal fine structure

scientific article published on 01 February 2000

Electrical stimulation of the auditory nerve: II. Effect of stimulus waveshape on single fibre response properties

scientific article published on 01 April 1999

Electrical stimulation of the auditory nerve: direct current measurement in vivo.

scientific article published in April 1999

Electrical stimulation of the auditory nerve: single neuron strength-duration functions in deafened animals

scientific article published on 01 March 2001

Electrical stimulation of the auditory nerve: the effect of electrode position on neural excitation

scientific article published in March 1993

Electrochemical and biological performance of chronically stimulated conductive hydrogel electrodes

scientific article published on 09 April 2020

Enhanced auditory neuron survival following cell-based BDNF treatment in the deaf guinea pig.

scientific article

Evaluation of focused multipolar stimulation for cochlear implants in acutely deafened cats

scientific article published in December 2014

Evaluation of stimulus parameters and electrode geometry for an effective suprachoroidal retinal prosthesis

scientific article published on 18 May 2010

Examining the auditory nerve fiber response to high rate cochlear implant stimulation: chronic sensorineural hearing loss and facilitation.

scientific article

Fate of embryonic stem cells transplanted into the deafened mammalian cochlea.

scientific article published on January 2006

First-in-human trial of a novel suprachoroidal retinal prosthesis

scientific article

Focused electrical stimulation using a single current source

scientific article published on 03 July 2018

Functional and morphological response of the stria vascularis following a sensorineural hearing loss.

scientific article

Gene therapy boosts the bionic ear.

scientific article published in April 2014

Hearing, vocalization and the external ear of a marsupial, the northern Quoll, Dasyurus hallucatus.

scientific article

Hydrogel limits stem cell dispersal in the deaf cochlea: implications for cochlear implants.

scientific article published on 27 November 2012

Impedance changes in chronically implanted and stimulated cochlear implant electrodes

scientific article published on 25 November 2013

Implanted Material Tolerance Studies for a Multiple-channel Cochlear Prosthesis

Implanted Material Tolerance Studies for a Multiple-channel Cochlear Prosthesis

In vivo and in vitro comparison of the charge injection capacity of platinum macroelectrodes.

scientific article published on 3 November 2014

In vivo feasibility of epiretinal stimulation using ultrananocrystalline diamond electrodes

scientific article published on 13 July 2020

Long-term sensorineural hearing loss induces functional changes in the rat auditory nerve.

scientific article published in December 2004

Maturation of the cortical auditory evoked potential in infants and young children

scientific article published on 3 February 2006

Measurement of forces at the tip of a cochlear implant during insertion

scientific article published in April 2014

Meningitis after cochlear implantation

scientific article published on November 2007

Mesoporous silica supraparticles for sustained inner-ear drug delivery

scientific article published on 5 August 2014

Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss

scientific article

Mold-templated inorganic-organic hybrid supraparticles for codelivery of drugs

scientific article published on 16 October 2014

Nanoporous peptide particles for encapsulating and releasing neurotrophic factors in an animal model of neurodegeneration

scientific article published on 21 May 2012

Neonatal sensorineural hearing loss affects neurone size in cat auditory midbrain

scientific article

Neural prostheses and brain plasticity

scientific article

Neurotrophic factors and neural prostheses: potential clinical applications based upon findings in the auditory system.

scientific article

Neurotrophin gene therapy for sustained neural preservation after deafness

scientific article

Neurotrophins and electrical stimulation for protection and repair of spiral ganglion neurons following sensorineural hearing loss.

scientific article

Onset of ototoxicity in the cat is related to onset of auditory function.

scientific article published on December 1995

Partial hearing loss in the macaque following the co-administration of kanamycin and ethacrynic acid.

scientific article published on January 1994

Pneumococcal meningitis post-cochlear implantation: potential routes of infection and pathophysiology

scientific article

Pneumococcal meningitis post-cochlear implantation: preventative measures

scientific article

Pneumococcal meningitis threshold model: A potential tool to assess infectious risk of new or existing inner ear surgical interventions

scientific article

Pneumococcal meningitis: development of a new animal model

scientific article

Polypyrrole-coated electrodes for the delivery of charge and neurotrophins to cochlear neurons.

scientific article

Preface: Special section on medical bionics

scientific article published on 01 December 2014

Profound hearing loss in the cat following the single co-administration of kanamycin and ethacrynic acid.

scientific article published on November 1993

Progressive ototoxicity of neomycin monitored using derived brainstem response audiometry

scientific article published on May 1985

Promoting neurite outgrowth from spiral ganglion neuron explants using polypyrrole/BDNF-coated electrodes.

scientific article published in October 2009

Protective effects of local administration of ciprofloxacin on the risk of pneumococcal meningitis after cochlear implantation

scientific article

Reduction in excitability of the auditory nerve following acute electrical stimulation at high stimulus rates: III. Capacitive versus non-capacitive coupling of the stimulating electrodes.

scientific article published in February 1998

Reduction in excitability of the auditory nerve following electrical stimulation at high stimulus rates.

scientific article

Reduction in excitability of the auditory nerve following electrical stimulation at high stimulus rates. II. Comparison of fixed amplitude with amplitude modulated stimuli

scientific article

Reduction in excitability of the auditory nerve following electrical stimulation at high stimulus rates. IV. Effects of stimulus intensity

scientific article published in June 1999

Reduction in excitability of the auditory nerve following electrical stimulation at high stimulus rates: V. Effects of electrode surface area

scientific article published in August 2000

Response of the primary auditory cortex to electrical stimulation of the auditory nerve in the congenitally deaf white cat.

scientific article published in October 1997

Retinal Changes in an ATP-Induced Model of Retinal Degeneration

scientific article published on 29 April 2016

Safety and efficacy of explanting or replacing suprachoroidal electrode arrays in a feline model

scientific article published on 10 October 2014

Scanning electron microscopy of chronically stimulated platinum intracochlear electrodes

scientific article

Schwann cells genetically modified to express neurotrophins promote spiral ganglion neuron survival in vitro.

scientific article

Sensorineural hearing loss during development: morphological and physiological response of the cochlea and auditory brainstem.

scientific article

Special issue on medical bionics

scientific article published on 23 October 2009

Special section on medical bionics

scientific article published on 27 November 2012

Spiral ganglion neuron survival and function in the deafened cochlea following chronic neurotrophic treatment.

scientific article

Stimulation of a Suprachoroidal Retinal Prosthesis Drives Cortical Responses in a Feline Model of Retinal Degeneration

scientific article

Stimulus induced pH changes in cochlear implants: an in vitro and in vivo study

scientific article

Suprachoroidal electrical stimulation: effects of stimulus pulse parameters on visual cortical responses

scientific article published on 08 August 2013

Surface microstructure of the perilymphatic space: implications for cochlear implants and cell- or drug-based therapies.

scientific article published in May 2004

Surgical access to the mammalian cochlea for cell-based therapies

scientific article

Survival of partially differentiated mouse embryonic stem cells in the scala media of the guinea pig cochlea.

scientific article

Synaptic plasticity after chemical deafening and electrical stimulation of the auditory nerve in cats.

scientific article

Synergy between TGF-beta 3 and NT-3 to promote the survival of spiral ganglia neurones in vitro

scientific article published on 01 January 1998

The Postnatal Growth of the Temporal Bone and its Implications for Cochlear Implantation in Children

article

The development of neural stimulators: a review of preclinical safety and efficacy studies

scientific article published on 14 May 2018

Threshold shift: effects of cochlear implantation on the risk of pneumococcal meningitis

scientific article

Transmural impedance detects graded changes of inflammation in experimental colitis

scientific article published on 19 February 2020

Visual cortex responses to suprachoroidal electrical stimulation of the retina: effects of electrode return configuration

scientific article published on 18 May 2012

Visual prostheses for the blind.

scientific article published on 14 August 2013

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