List of works - Meryem Köse

1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases

scientific article

2-Amino[1,2,4]triazolo[1,5-c]quinazolines and Derived Novel Heterocycles: Syntheses and Structure-Activity Relationships of Potent Adenosine Receptor Antagonists.

scientific article published on 17 August 2016

3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17

scientific article published on 05 September 2018

6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84).

scientific article published on 20 March 2018

8-Benzyltetrahydropyrazino[2,1-f]purinediones: water-soluble tricyclic xanthine derivatives as multitarget drugs for neurodegenerative diseases.

scientific article

An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights

scientific article published on 27 November 2019

Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies

scientific article

Cyclopropane-Containing Fatty Acids from the Marine Bacterium sp. 011 with Antimicrobial and GPR84 Activity ⬇️

scientific article published on 08 October 2018

Development of [(3)H]2-Carboxy-4,6-dichloro-1H-indole-3-propionic Acid ([(3)H]PSB-12150): A Useful Tool for Studying GPR17

scientific article published on 16 January 2014

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84.

scientific article published on 13 April 2017

Fluorescent-labeled selective adenosine A2B receptor antagonist enables competition binding assay by flow cytometry

scientific article published on 22 April 2018

Focused screening to identify new adenosine kinase inhibitors

scientific article

GPCRs and EGFR - Cross-talk of membrane receptors in cancer.

scientific article

High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

scientific article

Nucleoside/nucleobase transporters: drug targets of the future?

scientific article published on May 2009

Similarities and differences in affinity and binding modes of tricyclic pyrimido- and pyrazinoxanthines at human and rat adenosine receptors.

scientific article

Synthesis and Analgesic Activity of Annelated Xanthine Derivatives in Experimental Models in Rodents.

scientific article published on 6 August 2015

Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido- and diazepinopurinediones.

scientific article

Synthesis of Novel Pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine Derivatives: Potent and Selective Adenosine A3Receptor Antagonists

scientific article published on 30 August 2013

Synthesis, biological activity and molecular modelling studies of tricyclic alkylimidazo-, pyrimido- and diazepinopurinediones

scientific article published on 02 April 2013

List of works by Meryem Köse

1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases

2-Amino[1,2,4]triazolo[1,5-c]quinazolines and Derived Novel Heterocycles: Syntheses and Structure-Activity Relationships of Potent Adenosine Receptor Antagonists.

3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17

6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84).

8-Benzyltetrahydropyrazino[2,1-f]purinediones: water-soluble tricyclic xanthine derivatives as multitarget drugs for neurodegenerative diseases.

An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights

Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies

Cyclopropane-Containing Fatty Acids from the Marine Bacterium sp. 011 with Antimicrobial and GPR84 Activity ⬇️

Development of [(3)H]2-Carboxy-4,6-dichloro-1H-indole-3-propionic Acid ([(3)H]PSB-12150): A Useful Tool for Studying GPR17

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84.

Fluorescent-labeled selective adenosine A2B receptor antagonist enables competition binding assay by flow cytometry

Focused screening to identify new adenosine kinase inhibitors

GPCRs and EGFR - Cross-talk of membrane receptors in cancer.

High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

Nucleoside/nucleobase transporters: drug targets of the future?

Similarities and differences in affinity and binding modes of tricyclic pyrimido- and pyrazinoxanthines at human and rat adenosine receptors.

Synthesis and Analgesic Activity of Annelated Xanthine Derivatives in Experimental Models in Rodents.

Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido- and diazepinopurinediones.

Synthesis of Novel Pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine Derivatives: Potent and Selective Adenosine A3Receptor Antagonists

Synthesis, biological activity and molecular modelling studies of tricyclic alkylimidazo-, pyrimido- and diazepinopurinediones