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List of works by In Kyoung Lim

Accumulation of cytolytic CD8+ T cells in B16-melanoma and proliferation of mature T cells in TIS21-knockout mice after T cell receptor stimulation.

scientific article published in August 2014

B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFκB pathways which enhances transcription of MnSOD by accelerating IκBα degradation in normal and cancer cells.

scientific article published on 18 September 2013

B-cell translocation gene 2: expression in the rat ovary and potential association with adenine nucleotide translocase 2 in mitochondria.

scientific article

Biological methylation of myelin basic protein: Enzymology and biological significance

scientific article published on May 1, 1997

C-terminus-deleted FoxM1 is expressed in cancer cell lines and induces chromosome instability.

scientific article published on 24 April 2013

Compartmental inhibition of hepatic glutathione reductase activities by 1,3-bis(2-chloroethyl)-N-nitrosourea (BCNU) in Sprague-Dawley and Fischer-344 rats.

scientific article published in March 2004

Cytoplasmic retention of p-Erk1/2 and nuclear accumulation of actin proteins during cellular senescence in human diploid fibroblasts

scientific article published on 01 November 2000

Differential expression of O6-methylguanine-DNA methyltransferase during diethylnitrosamine-induced carcinogenesis and liver regeneration in Sprague-Dawley male rats

scientific article published on 01 August 1999

Differential expression of TIS21 and TIS1 genes in the various organs of Balb/c mice, thymic carcinoma tissues and human cancer cell lines

scientific article published on 01 January 1995

Downregulation of PEA-15 reverses G1 arrest, and nuclear and chromatin changes of senescence phenotype via pErk1/2 translocation to nuclei

scientific article

Effect of nodularin on the expression of glutathione S-transferase placental form and proliferating cell nuclear antigen in N-nitrosodiethylamine initiated hepatocarcinogenesis in the male Fischer 344 rat.

scientific article published in August 1999

Expression of androgen receptor and its implication in hepatoma cells

scientific article published on 01 May 1997

Expression of rat BTG(3) gene, Rbtg3, is regulated by redox changes

scientific journal article

Expression of the tumor necrosis factor alpha gene and early response genes by nodularin, a liver tumor promoter, in primary cultured rat hepatocytes

scientific article published on 01 January 1997

Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1

scientific article

Friendship in research: the Japan-Korea Symposia on Cancer and Ageing

scientific article published on 02 April 2008

Identification of highly methylated arginine residues in an endogenous 20-kDa polypeptide in cancer cells.

scientific article published in January 1999

Inhibition of bladder cancer invasion by Sp1-mediated BTG2 expression via inhibition of DNA methyltransferase 1

scientific article published on 30 October 2014

Iron chelation-induced senescence-like growth arrest in hepatocyte cell lines: association of transforming growth factor beta1 (TGF-beta1)-mediated p27Kip1 expression.

scientific article published on September 2002

Loss of p21(Sdi1) expression in senescent cells after DNA damage accompanied with increase of miR-93 expression and reduced p53 interaction with p21(Sdi1) gene promoter.

scientific article published on 21 March 2011

Marked inhibition of testosterone biosynthesis by the hepatotoxin nodularin due to apoptosis of Leydig cells.

scientific article

Phosphorylated extracellular signal-regulated protein kinases 1 and 2 phosphorylate Sp1 on serine 59 and regulate cellular senescence via transcription of p21Sdi1/Cip1/Waf1.

scientific article published on 24 March 2009

Pronase-based assay method for O6-methylguanine-DNA methyltransferase

scientific article published on 01 May 1996

Protein methylation and interaction with the antiproliferative gene, BTG2/TIS21/Pc3.

scientific article published on March 2014

Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells.

scientific article published on 31 December 2010

Sensitization of metformin-cytotoxicity by dichloroacetate via reprogramming glucose metabolism in cancer cells

scientific article published on 27 January 2014

Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and methylation of p16(INK4A) exon 1 in hepatocellular

scientific article published in March 2001

Shifting p53-induced senescence to cell death by TIS21(/BTG2/Pc3) gene through posttranslational modification of p53 protein.

scientific article

Skp2 enhances polyubiquitination and degradation of TIS21/BTG2/PC3, tumor suppressor protein, at the downstream of FoxM1.

scientific article

Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats.

scientific article

Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fisher 344 male rats [Mechanisms of Ageing and Development 123 (2002) 1665-1680].

scientific article

Stress-induced NF-κB activation differentiates promyelocytic leukemia cells to macrophages in response to all-trans-retinoic acid

scientific article published on 27 November 2014

TIS21 (/BTG2/PC3) as a link between ageing and cancer: cell cycle regulator and endogenous cell death molecule.

scientific article

TIS21(/BTG2/PC3) inhibits interleukin-6 expression via downregulation of STAT3 pathway.

scientific article published on August 2013

TIS21/BTG2 inhibits breast cancer growth and progression by differential regulation of mTORc1 and mTORc2-AKT1-NFAT1-PHLPP2 signaling axis.

scientific article

TIS21/BTG2 inhibits invadopodia formation by downregulating reactive oxygen species level in MDA-MB-231 cells.

scientific article published on 2 August 2013

TIS21/BTG2/PC3 enhances downregulation of c-Myc during differentiation of HL-60 cells by activating Erk1/2 and inhibiting Akt in response to all-trans-retinoic acid.

scientific article

TIS21/BTG2/PC3 is expressed through PKC-delta pathway and inhibits binding of cyclin B1-Cdc2 and its activity, independent of p53 expression.

scientific article published on September 2004

The eleventh Korea-Japan-Germany joint symposium on cancer and ageing research.

scientific article published on 28 February 2013

The seventh Korea-Japan joint symposium on cancer and ageing research: molecular targets in cancer and ageing research.

scientific article

Two synaptotagmin genes, Syt1 and Syt4, are differentially regulated in adult brain and during postnatal development following kainic acid-induced seizures

scientific journal article