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List of works by Marcos Hikari Toyama

A low protein diet alters gene expression in rat pancreatic islets.

scientific article published in February 2004

A new C-type animal lectin isolated from Bothrops pirajai is responsible for the snake venom major effects in the isolated kidney

scientific article published in January 2005

A quick procedure for the isolation of dimeric piratoxins-I and II, two myotoxins from Bothrops pirajai snake venom. N-terminal sequencing

scientific article published on 01 December 1995

A rapid procedure for the isolation of the Lys-49 myotoxin II from Bothrops moojeni (caissaca) venom: biochemical characterization, crystallization, myotoxic and edematogenic activity

scientific article published on 01 March 1998

A trypsin inhibitor from Peltophorum dubium seeds active against pest proteases and its effect on the survival of Anagasta kuehniella (Lepidoptera: Pyralidae)

scientific article published on May 2, 2003

A trypsin inhibitor from Sapindus saponaria L. seeds: purification, characterization, and activity towards pest insect digestive enzyme.

scientific article published on January 2011

Abdominal hyperalgesia in secretory phospholipase A2-induced rat pancreatitis: distinct roles of NK1 receptors

scientific article published on 11 May 2011

Amino acid sequence of TsTX-V, an alpha-toxin from Tityus serrulatus scorpion venom, and its effect on K+ permeability of beta-cells from isolated rat islets of Langerhans.

scientific article published on April 1995

Amino acid sequence of piratoxin-I, a myotoxin from Bothrops pirajai snake venom, and its biological activity after alkylation with p-bromophenacyl bromide

scientific article published on 01 October 1998

Amino acid sequence of piratoxin-II, a myotoxic lys49 phospholipase A(2) homologue from Bothrops pirajai venom

scientific article published on 01 March 2000

Anti-leishmanial effects of purified compounds from aerial parts of Baccharis uncinella C. DC. (Asteraceae)

scientific article published on October 1, 2010

Anti-ophidian activity of Bredemeyera floribunda Willd. (Polygalaceae) root extract on the local effects induced by Bothrops jararacussu venom

scientific article published on 03 December 2018

Antiophidic solanidane steroidal alkaloids from Solanum campaniforme

scientific article published on 30 September 2011

Biochemical and biomechanical analysis of tendons of caged and penned chickens.

scientific article published on January 2004

Biochemical characterization of a lectin from Delonix regia seeds.

scientific article published in May 2002

Biochemical characterization of two crotamine isoforms isolated by a single step RP-HPLC from Crotalus durissus terrificus (South American rattlesnake) venom and their action on insulin secretion by pancreatic islets

scientific article published on 01 March 2000

Blood amino acids concentration during insulin induced hypoglycemia in rats: the role of alanine and glutamine in glucose recovery

scientific article published on 08 September 2006

Bothropoides insularis venom cytotoxicity in renal tubular epithelia cells.

scientific article published on 27 May 2014

Bothropoides pauloensis venom effects on isolated perfused kidney and cultured renal tubular epithelial cells.

scientific article

Bothrops leucurus venom induces nephrotoxicity in the isolated perfused kidney and cultured renal tubular epithelia.

scientific article published on 2 November 2012

Catalytic Thr or Ser Residue Modulates Structural Switches in 2-Cys Peroxiredoxin by Distinct Mechanisms

scientific article

Characterization of the insulinotropic action of a phospholipase A2 isolated from Crotalus durissus collilineatus rattlesnake venom on rat pancreatic islets.

scientific article published in February 2005

Circulating leukocyte heat shock protein 70 (HSP70) and oxidative stress markers in rats after a bout of exhaustive exercise

scientific article published on 01 June 2006

Comparative studies of the anti-leishmanial activity of three Crotalus durissus ssp. venoms.

scientific article

Crotacetin, a novel snake venom C-type lectin homolog of convulxin, exhibits an unpredictable antimicrobial activity.

scientific article

Crotapotin induced modification of T lymphocyte proliferative response through interference with PGE2 synthesis

scientific article published on September 15, 2003

Crystal structure of neurotoxin Ts1 from Tityus serrulatus provides insights into the specificity and toxicity of scorpion toxins

scientific article

Crystallization and preliminary X-ray diffraction analysis of a new chitin-binding protein from Parkia platycephala seeds

scientific article

Crystallization and preliminary X-ray diffraction studies of piratoxin II, a phospholipase A2 isolated from the venom of Bothrops pirajai

scientific article published on 01 November 1998

Crystallization and preliminary X-ray diffraction studies of piratoxin III, a D-49 phospholipase A2 from the venom of Bothrops pirajai

scientific article published on 01 June 1999

Cytotoxicity of active ingredients extracted from plants of the Brazilian "Cerrado".

scientific article

Decreased cholinergic stimulation of insulin secretion by islets from rats fed a low protein diet is associated with reduced protein kinase calpha expression

scientific article published on 01 March 2003

Determination of Crotalus durissus cascavella venom components that induce renal toxicity in isolated rat kidneys

article

Effect of crotapotin and heparin on the rat paw oedema induced by different secretory phospholipases A2

scientific article published on 01 February 2000

Effects of Bothrops pirajai venom on the mouse extensor digitorum longus (EDL) muscle preparation

scientific article published on 01 August 1999

Effects of Tityus serrulatus scorpion venom on lung mechanics and inflammation in mice

scientific article published on 01 June 2009

Effects of morin on snake venom phospholipase A2 (PLA2).

scientific article published on 23 September 2005

Enzymatic characterization of a novel phospholipase A2 from Crotalus durissus cascavella rattlesnake (Maracambóia) venom

scientific article published on 01 October 2000

Enzymatic characterization of a novel phospholipase A2 from Crotalus durissus cascavella rattlesnake (Maracambóia) venom

scientific article published on 01 November 2000

Evaluation of KIM-1 as an early biomarker of snakebite-induced AKI in mice

scientific article published on 15 June 2018

Evaluation of Macroalgae Sulfated Polysaccharides on the Leishmania (L.) amazonensis Promastigote

scientific article published on March 20, 2013

Extracellular matrix of porcine pericardium: biochemistry and collagen architecture.

scientific article published on 3 December 2007

Human neutrophil migration in vitro induced by secretory phospholipases A2: a role for cell surface glycosaminoglycans

scientific article published in January 2002

In vitro studies on Bothrops venoms cytotoxic effect on tumor cells.

scientific article

Increased L-CPT-1 activity and altered gene expression in pancreatic islets of malnourished adult rats: a possible relationship between elevated free fatty acid levels and impaired insulin secretion

scientific article published on 24 May 2007

Inflammatory oedema induced by phospholipases A2 isolated from Crotalus durissus sp. in the rat dorsal skin: a role for mast cells and sensory C-fibers

scientific article

Inhibition of inducible nitric oxide synthase-derived nitric oxide as a therapeutical target for acute pancreatitis induced by secretory phospholipase A2.

scientific article

Involvement of Nitric Oxide on Bothropoides insularis Venom Biological Effects on Murine Macrophages In Vitro.

scientific article

Ischaemia-reperfusion mechanisms in acute pancreatitis.

scientific article published on January 1996

Isolation and preliminary enzymatic characterization of a novel PLA2 from Crotalus durissus collilineatus venom

scientific article published on 01 March 2002

Isolation of protein factors from opossum (Didelphis albiventris) serum which protect against Bothrops jararaca venom

scientific article published on 01 September 1996

Isolation, homology modeling and renal effects of a C-type natriuretic peptide from the venom of the Brazilian yellow scorpion (Tityus serrulatus).

scientific article published on 31 July 2013

L-Aminoacid Oxidase from Bothrops leucurus Venom Induces Nephrotoxicity via Apoptosis and Necrosis

scientific article published on 20 July 2015

Leishmania (Viannia) shawi purified antigens confer protection against murine cutaneous leishmaniasis

scientific article published on 14 December 2011

Leucocyte recruitment induced by type II phospholipases A2 into the rat pleural cavity

scientific article published on 01 December 2000

Modulation of the pharmacological effects of enzymatically-active PLA2 by BTL-2, an isolectin isolated from the Bryothamnion triquetrum red alga

scientific article

Myzobdella platensis (Hirundinida: Piscicolidae) is true parasite of blue crabs (Crustacea: Portunidae).

scientific article published in February 2009

Neuropathy of gastrointestinal Chagas' disease: immune response to myelin antigens

article

Novel protein from Labramia bojeri A. DC. seeds homologue to Kunitz-type trypsin inhibitor with lectin-like properties.

scientific article

Participation of Na(+) channels in the potentiation by Tityus serrulatus alpha-toxin TsTx-V of glucose-induced electrical activity and insulin secretion in rodent islet beta-cells

scientific article published on June 2003

Pharmacological and structural characterization of a novel phospholipase A2 from Micrurus dumerilii carinicauda venom

scientific article published on 29 September 2005

Proteins of Leishmania (Viannia) shawi confer protection associated with Th1 immune response and memory generation.

scientific article published on 30 March 2012

Purification and amino acid sequence of MP-III 4R D49 phospholipase A2 from Bothrops pirajai snake venom, a toxin with moderate PLA2 and anticoagulant activities and high myotoxic activity

scientific article published on 01 April 1999

Purification and biological effects of Araucaria angustifolia (Araucariaceae) seed lectin

scientific article published on 05 October 2006

Purification and characterization of a lectin from Crotalaria paulina seeds.

scientific article published in October 2004

Purification and characterization of an N-acetylglucosamine-binding lectin from Koelreuteria paniculata seeds and its effect on the larval development of Callosobruchus maculatus (Coleoptera: Bruchidae) and Anagasta kuehniella (Lepidoptera: Pyralida

scientific article

Purification and characterization of the biological effects of phospholipase A(2) from sea anemone Bunodosoma caissarum

scientific article

Purification and characterization of the first γ-phospholipase inhibitor (γPLI) from Bothrops jararaca snake serum.

scientific article published on 5 March 2018

Purification and preliminary crystallographic analysis of a new Lys49-PLA2 from B. Jararacussu.

scientific article published on 08 May 2008

Purification of a PHA-like chitin-binding protein from Acacia farnesiana seeds: a time-dependent oligomerization protein.

scientific article

Renal Effects of Supernatant from Macrophages Activated by Crotalus durissus cascavella Venom: The Role of Phospholipase A2 and Cyclooxygenase

scientific article published on 01 January 2003

Renal and cardiovascular effects of Bothrops marajoensis venom and phospholipase A2.

scientific article published on 28 December 2009

Renal and vascular effects of the natriuretic peptide isolated from Crotalus durissus cascavella venom

scientific article

Renal effects and vascular reactivity induced by Tityus serrulatus venom

scientific article published in September 2005

Renal effects of Bunodosoma caissarum crude extract: Prostaglandin and endothelin involvement

scientific article published on 23 August 2017

Solanidane and iminosolanidane alkaloids from Solanum campaniforme

scientific article published on 26 September 2013

Structural and biological characterization of a crotapotin isoform isolated from Crotalus durissus cascavella venom

scientific article published on 01 July 2003

Structural and functional characterization of basic PLA2 isolated from Crotalus durissus terrificus venom.

scientific article

Structural and functional characterization of myotoxin I, a Lys49 phospholipase A(2) homologue from Bothrops moojeni (Caissaca) snake venom.

scientific article published in January 2000

Structural basis for low catalytic activity in Lys49 phospholipases A2--a hypothesis: the crystal structure of piratoxin II complexed to fatty acid

scientific article

The amino acid sequence of ribitol dehydrogenase-F, a mutant enzyme with improved xylitol dehydrogenase activity

scientific article published on 01 May 1999

The effect of treatment with crotapotin on the evolution of experimental autoimmune neuritis induced in Lewis rats

scientific article published on 10 October 2006

The extract of the jellyfish Phyllorhiza punctata promotes neurotoxic effects

scientific article published on 11 February 2011

The pharmacological effect of Bothrops neuwiedii pauloensis (jararaca-pintada) snake venom on avian neuromuscular transmission.

scientific article published on 22 April 2003

The role of indomethacin and tezosentan on renal effects induced by Bothrops moojeni Lys49 myotoxin I

scientific article published on 26 May 2006

The structure of the D49 phospholipase A2 piratoxin III from Bothrops pirajai reveals unprecedented structural displacement of the calcium-binding loop: possiblerelationship to cooperative substrate binding

scientific article (publication date: February 2003)

TsTX-VII, a new toxin from Tityus serrulatus scorpion venom able to induce the release of neurotransmitters from rat brain synaptosomes not blocked by tetrodotoxin.

scientific article published in May 1997

cDNA cloning and 1.75 A crystal structure determination of PPL2, an endochitinase and N-acetylglucosamine-binding hemagglutinin from Parkia platycephala seeds

scientific article published on 01 September 2006

l-amino acid oxidase from Bothrops marajoensis causes nephrotoxicity in isolated perfused kidney and cytotoxicity in MDCK renal cells

scientific article published on 8 August 2015