List of works - Giovanna Bergamini

A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level.

scientific article published on 6 July 2016

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

scientific article

A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation

scientific article

Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

scientific article published on 9 May 2017

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in <i>ex vivo</i> human precision-cut lung slices

scientific article published on 24 December 2020

CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model.

scientific article

Catalytic in vivo protein knockdown by small-molecule PROTACs.

scientific article

Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors

scientific article published on 10 February 2016

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

scientific article

Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.

scientific article

Discovery of novel PI3Kγ/δ inhibitors as potential agents for inflammation

scientific article

Enhancement of IRES-Mediated Translation of the c-myc and BiP mRNAs by the Poly(A) Tail Is Independent of Intact eIF4G and PABP

article published in 2004

Human cytomegalovirus product UL44 downregulates the transactivation of HIV-1 long terminal repeat.

scientific article published on March 1998

Identifying drug targets in tissues and whole blood with thermal-shift profiling

scientific article published on 20 January 2020

Intracellular production of a major cytomegalovirus antigenic protein in the methylotrophic yeast Pichia pastoris

scientific article published on 01 October 1996

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.

scientific article published on 3 March 2018

Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target

scientific article published on 08 January 2020

Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system

scientific article published on December 2000

SAR studies around a series of triazolopyridines as potent and selective PI3Kγ inhibitors

scientific article

Screening Pools of Compounds against Multiple Endogenously Expressed Targets in a Chemoproteomics Binding Assay.

scientific article published on 13 July 2015

Systematic analysis of protein turnover in primary cells.

scientific article published on 15 February 2018

List of works by Giovanna Bergamini

A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level.

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation

Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in <i>ex vivo</i> human precision-cut lung slices

CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model.

Catalytic in vivo protein knockdown by small-molecule PROTACs.

Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.

Discovery of novel PI3Kγ/δ inhibitors as potential agents for inflammation

Enhancement of IRES-Mediated Translation of the c-myc and BiP mRNAs by the Poly(A) Tail Is Independent of Intact eIF4G and PABP

Human cytomegalovirus product UL44 downregulates the transactivation of HIV-1 long terminal repeat.

Identifying drug targets in tissues and whole blood with thermal-shift profiling

Intracellular production of a major cytomegalovirus antigenic protein in the methylotrophic yeast Pichia pastoris

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.

Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target

Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system

SAR studies around a series of triazolopyridines as potent and selective PI3Kγ inhibitors

Screening Pools of Compounds against Multiple Endogenously Expressed Targets in a Chemoproteomics Binding Assay.

Systematic analysis of protein turnover in primary cells.