List of works - Giulia Chemi

(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements, Structural and Biological Investigation

scientific article published on 16 February 2018

A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents

A light in the dark: state of the art and perspectives in optogenetics and optopharmacology for restoring vision

scientific article published on 25 March 2019

Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation.

scientific article published on 13 November 2017

An integrated in silico screening strategy for identifying promising disruptors of p53-MDM2 interaction

scientific article published on 16 August 2019

Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and a

scholarly article by Alessandra Vallone et al published 25 April 2018 in European Journal of Medicinal Chemistry

Breakthroughs in Computational Approaches for Drug Discovery

Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II)

scientific article published on 31 May 2019

Computational Tool for Fast in silico Evaluation of hERG K+ Channel Affinity

scientific article published on 23 February 2017

Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems

scientific article published on 04 September 2019

First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents

scientific article published on 9 June 2017

Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach

scientific article published on 13 August 2019

Identification of novel fluorescent probes preventing PrPSc replication in prion diseases

scientific article published on November 2016

Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies

scientific article published on 31 July 2018

Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents

scientific article published on 12 November 2019

Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX.

scientific article published on 24 April 2017

Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents

scientific article published on 03 November 2018

Synthesis, Molecular Modelling and Biological Studies of 3-hydroxypyrane- 4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors

scientific article published on 01 January 2019

Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold

scientific article published on 09 August 2019

List of works by Giulia Chemi