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List of works by Mark Chambers

A DNA vaccine encoding MPB83 from Mycobacterium bovis reduces M. bovis dissemination to the kidneys of mice and is expressed in primary cell cultures of the European badger (Meles meles)

scientific article published on 01 October 2001

A co-culture model of the bovine alveolus

scientific article published on 01 April 2019

A guinea pig model of low-dose Mycobacterium bovis aerogenic infection

scientific article published on 01 June 2001

A lymphocyte transformation assay for the detection of Mycobacterium bovis infection in the Eurasian badger (Meles meles)

scientific article published on 01 September 1999

A review of infection of wildlife hosts with Mycobacterium bovis and the diagnostic difficulties of the 'no visible lesion' presentation.

scientific article published on June 2009

A single dose of killed Mycobacterium bovis BCG in a novel class of adjuvant (Novasome) protects guinea pigs from lethal tuberculosis.

scientific article published on February 2004

An AC electrokinetic impedance immunosensor for rapid detection of tuberculosis

scientific article published on 01 December 2013

Animal-side serologic assay for rapid detection of Mycobacterium bovis infection in multiple species of free-ranging wildlife

scientific article published on 07 July 2008

Antigen specific immunological responses of badgers (Meles meles) experimentally infected with Mycobacterium bovis

scientific article published on 17 November 2007

Assessment of different formulations of oral Mycobacterium bovis Bacille Calmette-Guérin (BCG) vaccine in rodent models for immunogenicity and protection against aerosol challenge with M. bovis

scientific article published on 26 September 2008

Association of quantitative interferon-γ responses with the progression of naturally acquired Mycobacterium bovis infection in wild European badgers (Meles meles).

scientific article published in February 2015

BCG vaccination reduces risk of tuberculosis infection in vaccinated badgers and unvaccinated badger cubs

scientific article

Bacillus Calmette-Guérin vaccination reduces the severity and progression of tuberculosis in badgers.

scientific article

Behaviour of European badgers and non-target species towards candidate baits for oral delivery of a tuberculosis vaccine

scientific article

Bioreactor-Grown Bacillus of Calmette and Guérin (BCG) Vaccine Protects Badgers against Virulent Mycobacterium bovis When Administered Orally: Identifying Limitations in Baited Vaccine Delivery

scientific article published on 18 August 2020

Challenges in Veterinary Vaccine Development and Immunization

scientific article published on January 2016

Cloning and sequencing of badger (Meles meles) interferon gamma and its detection in badger lymphocytes.

scientific article

Comparison of the protective efficacy of bacille calmette-Guérin vaccination against aerosol challenge with Mycobacterium tuberculosis and Mycobacterium bovis.

scientific article published in June 2000

Correlation of ESAT-6-specific gamma interferon production with pathology in cattle following Mycobacterium bovis BCG vaccination against experimental bovine tuberculosis.

scientific article published on June 2002

Development and evaluation of a gamma-interferon assay for tuberculosis in badgers (Meles meles)

scientific article published on 20 December 2007

Diagnosis of tuberculosis in groups of badgers: an exploration of the impact of trapping efficiency, infection prevalence and the use of multiple tests.

scientific article published on 6 January 2016

Discovery of a polyomavirus in European badgers (Meles meles) and the evolution of host range in the family Polyomaviridae

scientific article

Effective DNA vaccination of cattle with the mycobacterial antigens MPB83 and MPB70 does not compromise the specificity of the comparative intradermal tuberculin skin test.

scientific article

Evaluation of a combination of SIFT-MS and multivariate data analysis for the diagnosis of Mycobacterium bovis in wild badgers.

scientific article published on 17 July 2009

Evaluation of a method to detect Mycobacterium bovis in air samples from infected Eurasian badgers (Meles meles) and their setts.

scientific article published in March 2013

Evaluation of the CervidTB STAT-PAK for the detection of Mycobacterium bovis infection in wild deer in Great Britain.

scientific article published on 05 August 2009

Field evaluation of candidate baits for oral delivery of BCG vaccine to European badgers, Meles meles

scientific article

Histopathogenesis of experimental Mycobacterium bovis infection in mice

scientific article published on 01 February 2006

Host-directed therapy targeting the Mycobacterium tuberculosis granuloma: a review

scientific article published on 28 October 2015

Immunohistochemical characterization of tuberculous and non-tuberculous lesionsin naturally infected European badgers (Meles meles).

scientific article published in May 2002

Immunological approaches to the control of tuberculosis in wildlife reservoirs.

scientific article

Immunological responses and protective immunity in BCG vaccinated badgers following endobronchial infection with Mycobacterium bovis

scientific article published on 14 November 2008

Immunological responses following experimental endobronchial infection of badgers (Meles meles) with different doses of Mycobacterium bovis

scientific article published on 21 September 2008

Immunological responses of Eurasian badgers (Meles meles) vaccinated with Mycobacterium bovis BCG (bacillus calmette guerin)

scientific article published on 01 May 2001

Improved serodetection of Mycobacterium bovis infection in badgers (Meles meles) using multiantigen test formats

article

In Vitro Evaluation of Eudragit Matrices for Oral Delivery of BCG Vaccine to Animals

scientific article published on 10 June 2019

Isolation and characterisation of alveolar type II pneumocytes from adult bovine lung

scientific article published in Scientific Reports

Isolation of Alveolar Type II Cells from Adult Bovine Lung

scientific article published on 15 March 2019

Long-term temporal trends and estimated transmission rates for Mycobacterium bovis infection in an undisturbed high-density badger (Meles meles) population

scientific article published on 28 March 2013

Method for assessing IFN-γ responses in guinea pigs during TB vaccine trials

scientific article published on 17 August 2012

Mycobacterium bovis infection in badger cubs: re-assessing the evidence for maternally derived immunological protection from advanced disease.

scientific article published on 3 May 2012

Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum

scientific article published on 02 January 2020

Non-acylated Mycobacterium bovis glycoprotein MPB83 binds to TLR1/2 and stimulates production of matrix metalloproteinase 9.

scientific article published on 26 August 2010

Optimisation of Mycobacterium bovis BCG Fermentation and Storage Survival

scientific article published on 22 September 2020

Oral vaccination of badgers (Meles meles) against tuberculosis: comparison of the protection generated by BCG vaccine strains Pasteur and Danish

scientific article published in May 2014

Oral vaccination of badgers (Meles meles) with BCG and protective immunity against endobronchial challenge with Mycobacterium bovis

scientific article published on 15 July 2010

Pelioid Hepatocellular Carcinoma in an Adult Eurasian Badger (Meles meles)

scientific article published on 15 August 2009

Performance of TB immunodiagnostic tests in Eurasian badgers (Meles meles) of different ages and the influence of duration of infection on serological sensitivity

scientific article (publication date: 17 November 2009)

Progress in the development of vaccines and diagnostic reagents to control tuberculosis in cattle.

scientific article

Protection of Eurasian badgers (Meles meles) from tuberculosis after intra-muscular vaccination with different doses of BCG

scientific article published on 07 April 2011

Protective efficacy induced by Mycobacterium bovis bacille Calmette-Guèrin can be augmented in an antigen independent manner by use of non-coding plasmid DNA

scientific article published on 15 November 2005

Protective immunity against Mycobacterium bovis induced by vaccination with Rv3109c--a member of the esat-6 gene family.

scientific article

Purification and Characterisation of Badger IgA and Its Detection in the Context of Tuberculosis

scientific article published on 02 November 2019

Quantitative interferon-gamma responses predict future disease progression in badgers naturally infected with Mycobacterium bovis

scientific article published on 11 October 2017

RNA encoding the MPT83 antigen induces protective immune responses against Mycobacterium tuberculosis infection.

scientific article

Review of the diagnosis and study of tuberculosis in non-bovine wildlife species using immunological methods.

scientific article

Review of the diagnosis of tuberculosis in non-bovid wildlife species using immunological methods--an update of published work since 2009.

scientific article

Secretion and functional expression of Mycobacterium bovis antigens MPB70 and MPB83 in lactic acid bacteria

scientific article published on 29 May 2019

Sex-related heterogeneity in the life-history correlates of Mycobacterium bovis infection in European badgers (Meles meles).

scientific article published on November 2013

Simple objective measurement of the cutaneous delayed-type hypersensitivity reaction to tuberculin using spectrophotometry.

scientific article

Spatial relationships between Eurasian badgers (Meles meles) and cattle infected with Mycobacterium bovis in Northern Spain.

scientific article published on 18 April 2013

Survival of Mycobacterium bovis BCG oral vaccine during transit through a dynamic in vitro model simulating the upper gastrointestinal tract of badgers

scientific article published on 19 April 2019

Testing of a palatable bait and compatible vaccine carrier for the oral vaccination of European badgers (Meles meles) against tuberculosis

scientific article published on 9 January 2017

The Effect of Oral Vaccination with Mycobacterium bovis BCG on the Development of Tuberculosis in Captive European Badgers (Meles meles).

scientific article published on 24 January 2017

The safety and immunogenicity of Bacillus Calmette-Guérin (BCG) vaccine in European badgers (Meles meles)

scientific article published on 09 May 2006

Transcutaneous immunization with lipid offers a new route of vaccination against Helicobacter pylori and a new candidate delivery vehicle

scientific article published on 01 March 2010

Use of an electronic nose to diagnose Mycobacterium bovis infection in badgers and cattle.

scientific article

Vaccination against tuberculosis in badgers and cattle: an overview of the challenges, developments and current research priorities in Great Britain.

scientific article

Validation of the BrockTB stat-pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy.

scientific article published on 13 February 2008

Value of existing serological tests for identifying badgers that shed Mycobacterium bovis

scientific article published on 01 May 2002

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