List of works - Giuseppe Giannini

A lymphotactin-producing monoclonal T-cell lymphoproliferative disorder with extreme lymphocytopenia and progressive leukoencephalopathy

scientific article published on 01 July 2006

Activation of three distinct RXR/RAR heterodimers induces growth arrest and differentiation of neuroblastoma cells

scientific article published on 01 October 1997

An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma

scientific article

Association of SULT1A1 Arg²¹³His polymorphism with male breast cancer risk: results from a multicenter study in Italy.

scientific article published on 11 November 2014

Association of low-penetrance alleles with male breast cancer risk and clinicopathological characteristics: results from a multicenter study in Italy.

scientific article published on 7 March 2013

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

scientific article published on 31 December 2014

BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: a population-based study in central Italy

article

BRCA1/BRCA2 rearrangements and CHEK2 common mutations are infrequent in Italian male breast cancer cases

article

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

scientific article published in July 1994

Circulating tumor cells: exploring intratumor heterogeneity of colorectal cancer

scientific article

Clinical and pathologic characteristics of BRCA-positive and BRCA-negative male breast cancer patients: results from a collaborative multicenter study in Italy

article

Clinical classification of BRCA1 DNA missense variants: H1686Q is a novel pathogenic mutation occurring in the ontogenetically invariant THV motif of the N-terminal BRCT domain

scientific article published on 01 September 2008

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 18 May 2011

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 20 February 2012

Delayed and defective anti-HIV IgM response in infants

scientific article published on 01 March 1987

Direct correlation between double K-RAS mutation and mucinous carcinoma. A case report.

scientific article published in February 2015

Does the search for large genomic rearrangements impact BRCAPRO carrier prediction?

scientific article published on 01 June 2007

Drug treatment in the development of mismatch repair defective acute leukemia and myelodysplastic syndrome.

scientific article

Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma

scientific article

Galectin-3 impairment of MYCN-dependent apoptosis-sensitive phenotype is antagonized by nutlin-3 in neuroblastoma cells

scientific article

Galectin-3 is a marker of favorable prognosis and a biologically relevant molecule in neuroblastic tumors.

scientific article published on 06 March 2014

Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

scientific article

Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy ⬇️

scientific article published on June 6, 2013

HE4 in the differential diagnosis of a pelvic mass: a case report.

scientific article

Human papilloma virus-dependent HMGA1 expression is a relevant step in cervical carcinogenesis

scientific article published on August 2008

Improving the accuracy of BRCA1/2 mutation prediction: validation of the novel country-customized IC software

scientific article published on 01 January 2006

Insight into genetic susceptibility to male breast cancer by multigene panel testing: Results from a multicenter study in Italy

scientific article published on 24 January 2019

International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation

scientific article published on 22 July 2010

Localization of a novel ryanodine receptor gene (RYR3) to human chromosome 15q14-q15 by in situ hybridization.

scientific article

MRE11 expression is impaired in gastric cancer with microsatellite instability.

scientific article

MYCN sensitizes human neuroblastoma to apoptosis by HIPK2 activation through a DNA damage response.

scientific article published on 20 December 2010

Metastatic colorectal cancer first-line treatment with bevacizumab: the impact of K-ras mutation

scientific article

MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness.

scientific article

Molecular mechanism of HMGA1 deregulation in human neuroblastoma.

scientific article

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells

scientific article

New mutations and protein variants of NBS1 are identified in cancer cell lines

scientific article published on 01 February 2003

Novel and known genetic variants for male breast cancer risk at 8q24.21, 9p21.3, 11q13.3 and 14q24.1: results from a multicenter study in Italy

scientific article published on 3 August 2015

Novel and recurrent BRCA2 mutations in Italian breast/ovarian cancer families widen the ovarian cancer cluster region boundaries to exons 13 and 14.

scientific article published on 14 November 2014

Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination

scientific article published on 19 November 2006

Optimizing the identification of risk-relevant mutations by multigene panel testing in selected hereditary breast/ovarian cancer families.

scientific article published on 22 December 2017

PALB2 mutations in male breast cancer: a population-based study in Central Italy

article

PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress

scientific article published on 6 September 2013

PRDX1 and PRDX6 are repressed in papillary thyroid carcinomas via BRAF V600E-dependent and -independent mechanisms.

scientific article published on 5 December 2013

Prevalence of BRCA1 and BRCA2 genomic rearrangements in a cohort of consecutive Italian breast and/or ovarian cancer families

scientific article published on 28 February 2007

The BRCAPRO 5.0 model is a useful tool in genetic counseling and clinical management of male breast cancer cases

scientific article

The CASP8 rs3834129 polymorphism and breast cancer risk in BRCA1 mutation carriers

scientific article published on 22 July 2010

The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1.

scientific article published on 2 March 2012

The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress.

scientific article

The coactivator CRTC1 promotes cell proliferation and transformation via AP-1

scholarly article

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

scientific article published on March 1995

Validation of the Ion Torrent PGM sequencing for the prospective routine molecular diagnostic of colorectal cancer

scientific article published on 11 April 2015

Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer: a case report.

scientific article published on 22 April 2014

cDNA cloning reveals a tissue specific expression of alternatively spliced transcripts of the ryanodine receptor type 3 (RyR3) calcium release channel

scientific article published on September 1996

List of works by Giuseppe Giannini

A lymphotactin-producing monoclonal T-cell lymphoproliferative disorder with extreme lymphocytopenia and progressive leukoencephalopathy

Activation of three distinct RXR/RAR heterodimers induces growth arrest and differentiation of neuroblastoma cells

An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma

Association of SULT1A1 Arg²¹³His polymorphism with male breast cancer risk: results from a multicenter study in Italy.

Association of low-penetrance alleles with male breast cancer risk and clinicopathological characteristics: results from a multicenter study in Italy.

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: a population-based study in central Italy

BRCA1/BRCA2 rearrangements and CHEK2 common mutations are infrequent in Italian male breast cancer cases

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

Circulating tumor cells: exploring intratumor heterogeneity of colorectal cancer

Clinical and pathologic characteristics of BRCA-positive and BRCA-negative male breast cancer patients: results from a collaborative multicenter study in Italy

Clinical classification of BRCA1 DNA missense variants: H1686Q is a novel pathogenic mutation occurring in the ontogenetically invariant THV motif of the N-terminal BRCT domain

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

Delayed and defective anti-HIV IgM response in infants

Direct correlation between double K-RAS mutation and mucinous carcinoma. A case report.

Does the search for large genomic rearrangements impact BRCAPRO carrier prediction?

Drug treatment in the development of mismatch repair defective acute leukemia and myelodysplastic syndrome.

Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma

Galectin-3 impairment of MYCN-dependent apoptosis-sensitive phenotype is antagonized by nutlin-3 in neuroblastoma cells

Galectin-3 is a marker of favorable prognosis and a biologically relevant molecule in neuroblastic tumors.

Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy ⬇️

HE4 in the differential diagnosis of a pelvic mass: a case report.

Human papilloma virus-dependent HMGA1 expression is a relevant step in cervical carcinogenesis

Improving the accuracy of BRCA1/2 mutation prediction: validation of the novel country-customized IC software

Insight into genetic susceptibility to male breast cancer by multigene panel testing: Results from a multicenter study in Italy

International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation

Localization of a novel ryanodine receptor gene (RYR3) to human chromosome 15q14-q15 by in situ hybridization.

MRE11 expression is impaired in gastric cancer with microsatellite instability.

MYCN sensitizes human neuroblastoma to apoptosis by HIPK2 activation through a DNA damage response.

Metastatic colorectal cancer first-line treatment with bevacizumab: the impact of K-ras mutation

MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness.

Molecular mechanism of HMGA1 deregulation in human neuroblastoma.

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells

New mutations and protein variants of NBS1 are identified in cancer cell lines

Novel and known genetic variants for male breast cancer risk at 8q24.21, 9p21.3, 11q13.3 and 14q24.1: results from a multicenter study in Italy

Novel and recurrent BRCA2 mutations in Italian breast/ovarian cancer families widen the ovarian cancer cluster region boundaries to exons 13 and 14.

Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination

Optimizing the identification of risk-relevant mutations by multigene panel testing in selected hereditary breast/ovarian cancer families.

PALB2 mutations in male breast cancer: a population-based study in Central Italy

PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress

PRDX1 and PRDX6 are repressed in papillary thyroid carcinomas via BRAF V600E-dependent and -independent mechanisms.

Prevalence of BRCA1 and BRCA2 genomic rearrangements in a cohort of consecutive Italian breast and/or ovarian cancer families

The BRCAPRO 5.0 model is a useful tool in genetic counseling and clinical management of male breast cancer cases

The CASP8 rs3834129 polymorphism and breast cancer risk in BRCA1 mutation carriers

The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1.

The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress.

The coactivator CRTC1 promotes cell proliferation and transformation via AP-1

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

Validation of the Ion Torrent PGM sequencing for the prospective routine molecular diagnostic of colorectal cancer

Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer: a case report.

cDNA cloning reveals a tissue specific expression of alternatively spliced transcripts of the ryanodine receptor type 3 (RyR3) calcium release channel