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List of works by Thomas Manke

A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

scientific article published on 28 September 2018

A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis

scientific journal article

A transcription factor–based mechanism for mouse heterochromatin formation

scientific article published on 16 September 2012

Anterior gradient 2 and 3--two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells

scientific article published on 13 February 2013

CAPRI enables comparison of evolutionarily conserved RNA interacting regions.

scientific article published on 18 June 2019

CRUP: a comprehensive framework to predict condition-specific regulatory units

scientific article published on 08 November 2019

ChroMoS: an integrated web tool for SNP classification, prioritization and functional interpretation

scientific article published on June 19, 2013

Community-Driven Data Analysis Training for Biology

scientific article published on 01 June 2018

Correlating Protein–DNA and Protein–Protein Interaction Networks

scientific article published on October 10, 2003

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.

scientific article

DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex

scientific article published on 01 January 2019

DOT1L-mediated murine neuronal differentiation associates with H3K79me2 accumulation and preserves SOX2-enhancer accessibility

scientific article published on 15 October 2020

Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo

article

Dynamical quark effects on light quark masses

scientific article published on 01 November 2000

Epigenetic dynamics of monocyte-to-macrophage differentiation

scientific article published on 29 July 2016

Heterochromatin boundaries are hotspots for de novo kinetochore formation

scientific article published on 19 June 2011

High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila

scientific article published on October 2015

High-resolution TADs reveal DNA sequences underlying genome organization in flies.

scientific article published on 15 January 2018

Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4.

scientific article published on 23 February 2017

Integrating sequence, evolution and functional genomics in regulatory genomics

scientific article published on 30 January 2009

Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters

scientific article published on 10 November 2018

Lethality and entropy of protein interaction networks

scientific article published on 01 January 2005

MAPCap allows high-resolution detection and differential expression analysis of transcription start sites

scientific article published on 30 July 2019

MOF maintains transcriptional programs regulating cellular stress response.

scientific article published on 21 September 2015

MOF-associated complexes ensure stem cell identity and Xist repression.

scientific article

Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program

scientific article published on 23 December 2015

PASTAA: identifying transcription factors associated with sets of co-regulated genes

scientific article published on 09 December 2008

Parkour LIMS: high-quality sample preparation in next generation sequencing

scientific article published on 01 April 2019

Prioritization of gene regulatory interactions from large-scale modules in yeast

scientific article

Putative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites

scientific article

Quantifying the effect of sequence variation on regulatory interactions

scientific article

RELACS nuclei barcoding enables high-throughput ChIP-seq

scientific article published on 05 December 2018

Short ultraconserved promoter regions delineate a class of preferentially expressed alternatively spliced transcripts.

scientific article published on 4 August 2009

Standardizing chromatin research: a simple and universal method for ChIP-seq.

scientific article published on 23 December 2015

Statistical modeling of transcription factor binding affinities predicts regulatory interactions

scientific article

Suv39h-dependent H3K9me3 marks intact retrotransposons and silences LINE elements in mouse embryonic stem cells.

scientific article published on 26 June 2014

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle

scientific article

The NSL complex regulates housekeeping genes in Drosophila.

scientific article

The genomic landscape of the somatic linker histone subtypes H1.1 to H1.5 in human cells.

scientific article

The histone code reader Spin1 controls skeletal muscle development.

scientific article published on 23 November 2017

Transcription factor binding predictions using TRAP for the analysis of ChIP-seq data and regulatory SNPs

scientific article

Validation of reported genetic risk factors for periodontitis in a large-scale replication study.

scientific article published on 16 April 2013

Whole-exome sequencing identifies novel autosomal recessive DSG1 mutations associated with mild SAM syndrome

scientific article published on 19 November 2015

deepTools2: a next generation web server for deep-sequencing data analysis

scientific article

deepTools: a flexible platform for exploring deep-sequencing data.

scientific article

snakePipes: facilitating flexible, scalable and integrative epigenomic analysis

scientific article published on 01 November 2019