List of works - André Mateus

A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles

scientific article published on 13 November 2020

A high-throughput cell-based method to predict the unbound drug fraction in the brain

scientific article

Assessment of pharmacokinetic changes of meropenem during therapy in septic critically ill patients

scientific article

Bioaccumulation of therapeutic drugs by human gut bacteria

scientific article published in 2021

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

scientific article

Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability.

scientific article published on 3 September 2015

Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy

scientific article published on 11 March 2020

High-throughput functional characterization of protein phosphorylation sites in yeast

scientific article published on 18 October 2021

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.

scientific article

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

scientific article published on 10 April 2019

Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids

scientific article published on 11 May 2018

Intracellular drug bioavailability: a new predictor of system dependent drug disposition.

scientific article

Isocotoin suppresses hepatitis E virus replication through inhibition of heat shock protein 90

scientific article published on 14 December 2020

Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach

scientific article published on 3 February 2016

Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi-enzyme complexes in Escherichia coli

scientific article published on 03 February 2020

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

scientific article

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

scientific article

Rapid measurement of intracellular unbound drug concentrations.

scientific article published on 15 May 2013

SARS-CoV-2 infection remodels the host protein thermal stability landscape

scientific article published on 01 February 2021

Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection

scientific article published on 08 June 2020

The functional landscape of the human phosphoproteome

scientific article published on 09 December 2019

The functional proteome landscape of Escherichia coli

scientific article published on 09 December 2020

The rise of proteome‐wide biophysics

scientific article published in 2021

Thermal proteome profiling for interrogating protein interactions

scientific article published on 01 March 2020

Thermal proteome profiling in bacteria: probing protein state

scientific article published on 06 July 2018

Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes

scientific article

Transcriptional and Post-Transcriptional Polar Effects in Bacterial Gene Deletion Libraries

publication published on 07 September 2021

List of works by André Mateus

A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles

A high-throughput cell-based method to predict the unbound drug fraction in the brain

Assessment of pharmacokinetic changes of meropenem during therapy in septic critically ill patients

Bioaccumulation of therapeutic drugs by human gut bacteria

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability.

Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy

High-throughput functional characterization of protein phosphorylation sites in yeast

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids

Intracellular drug bioavailability: a new predictor of system dependent drug disposition.

Isocotoin suppresses hepatitis E virus replication through inhibition of heat shock protein 90

Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach

Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi-enzyme complexes in Escherichia coli

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

Rapid measurement of intracellular unbound drug concentrations.

SARS-CoV-2 infection remodels the host protein thermal stability landscape

Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection

The functional landscape of the human phosphoproteome

The functional proteome landscape of Escherichia coli

The rise of proteome‐wide biophysics

Thermal proteome profiling for interrogating protein interactions

Thermal proteome profiling in bacteria: probing protein state

Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes

Transcriptional and Post-Transcriptional Polar Effects in Bacterial Gene Deletion Libraries