List of works - Isao Kuraoka

A method for detecting genetic toxicity using the RNA synthesis response to DNA damage.

scientific article published in October 2011

A non-isotopic assay uses bromouridine and RNA synthesis to detect DNA damage responses.

scientific article published on 13 April 2010

A transfection reporter for the prevention of false-negative results in molecular beacon experiments.

scientific article published on 17 May 2013

Acetaldehyde forms covalent GG intrastrand crosslinks in DNA

scientific article published in Scientific Reports

An RNA synthesis inhibition assay for detecting toxic substances using click chemistry.

scientific article published in April 2014

An assay to detect DNA-damaging agents that induce nucleotide excision-repairable DNA lesions in living human cells

scientific article published on 22 May 2017

An in vitro method for detecting genetic toxicity based on inhibition of RNA synthesis by DNA lesions

scientific article

Assays for transcription elongation by RNA polymerase II using oligo(dC)-tailed template with single DNA damage

scientific article published on 01 January 2006

Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression

scientific article published on 20 October 2015

CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome

scientific article

Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana.

scientific article

Chemical Incorporation of Chain-Terminating Nucleoside Analogs as 3'-Blocking DNA Damage and Their Removal by Human ERCC1-XPF Endonuclease.

scientific article

Complete absence of Cockayne syndrome group B gene product gives rise to UV-sensitive syndrome but not Cockayne syndrome

scholarly article

DNA conformation-dependent activities of human mitochondrial RNA polymerase

scientific article published on 14 July 2009

DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics

scientific article

DNA repair protein XPA binds replication protein A (RPA).

scientific article published on February 1995

Diversity of Endonuclease V: From DNA Repair to RNA Editing

scientific article

Effects of 5',8-cyclodeoxyadenosine triphosphates on DNA synthesis

scientific article published on 16 November 2012

Effects of DNA lesions on the transcription reaction of mitochondrial RNA polymerase: implications for bypass RNA synthesis on oxidative DNA lesions.

scientific article

Effects of acetaldehyde-induced DNA lesions on DNA metabolism

scientific article published on 06 January 2020

Effects of endogenous DNA base lesions on transcription elongation by mammalian RNA polymerase II. Implications for transcription-coupled DNA repair and transcriptional mutagenesis.

scientific article published on 3 December 2002

Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword.

scientific article published on May 2015

Establishment of a human cell line stably overexpressing mouse Nip45 and characterization of Nip45 subcellular localization.

scientific article

FEN1 participates in repair of the 5'-phosphotyrosyl terminus of DNA single-strand breaks

scientific article published on 17 November 2015

Facile preparation of a fluorescent probe to detect the cellular ability of nucleotide excision repair.

scientific article published on 30 March 2017

Fluorescence detection of DNA mismatch repair in human cells

scientific article published in Scientific Reports

Fluorescence detection of cellular nucleotide excision repair of damaged DNA.

scientific article

Frequencies of mutagenic translesion DNA synthesis over cisplatin-guanine intra-strand crosslinks in lacZ plasmids propagated in human cells.

scientific article

Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication.

scientific article

Identification of Small Molecule Proliferating Cell Nuclear Antigen (PCNA) Inhibitor That Disrupts Interactions with PIP-box Proteins and Inhibits DNA Replication

scientific article

Inhibition of nucleotide excision repair by anti-XPA monoclonal antibodies which interfere with binding to RPA, ERCC1, and TFIIH.

scientific article published in September 2004

Inosine-specific ribonuclease activity of natural variants of human endonuclease V.

scientific article published in November 2016

Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair

scientific article

MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation

scientific article

Miscoding properties of 8-chloro-2'-deoxyguanosine, a hypochlorous acid-induced DNA adduct, catalysed by human DNA polymerases

scientific article published on 17 October 2012

Molecular evidence of the involvement of the nucleotide excision repair (NER) system in the repair of the mono(ADP-ribosyl)ated DNA adduct produced by pierisin-1, an apoptosis-inducing protein from the cabbage butterfly.

scientific article

Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex.

scientific article published on 9 December 2010

Nucleotide excision repair genes shaping embryonic development

scientific article published on 30 October 2019

Oligo swapping method for in vitro DNA repair substrate containing a single DNA lesion at a specific site

scientific article published on 12 November 2018

Oxygen free radical damage to DNA. Translesion synthesis by human DNA polymerase eta and resistance to exonuclease action at cyclopurine deoxynucleoside residues.

scientific article

Polymerization by DNA polymerase eta is blocked by cis-diamminedichloroplatinum(II) 1,3-d(GpTpG) cross-link: implications for cytotoxic effects in nucleotide excision repair-negative tumor cells.

scientific article published on 16 December 2009

RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS.

scientific article

Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease.

scientific article published in August 2000

Repair synthesis step involving ERCC1-XPF participates in DNA repair of the Top1-DNA damage complex.

scientific article published on 29 May 2015

Resonance assignments, solution structure, and backbone dynamics of the DNA- and RPA-binding domain of human repair factor XPA.

scientific article

Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA

scientific article

The SLX4 complex is a SUMO E3 ligase that impacts on replication stress outcome and genome stability

scientific article published on 18 December 2014

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

scientific article published on 2 May 2003

Xeroderma pigmentosum group F protein binds to Eg5 and is required for proper mitosis: implications for XP-F and XFE.

scientific article published in March 2012

List of works by Isao Kuraoka

A method for detecting genetic toxicity using the RNA synthesis response to DNA damage.

A non-isotopic assay uses bromouridine and RNA synthesis to detect DNA damage responses.

A transfection reporter for the prevention of false-negative results in molecular beacon experiments.

Acetaldehyde forms covalent GG intrastrand crosslinks in DNA

An RNA synthesis inhibition assay for detecting toxic substances using click chemistry.

An assay to detect DNA-damaging agents that induce nucleotide excision-repairable DNA lesions in living human cells

An in vitro method for detecting genetic toxicity based on inhibition of RNA synthesis by DNA lesions

Assays for transcription elongation by RNA polymerase II using oligo(dC)-tailed template with single DNA damage

Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression

CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome

Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana.

Chemical Incorporation of Chain-Terminating Nucleoside Analogs as 3'-Blocking DNA Damage and Their Removal by Human ERCC1-XPF Endonuclease.

Complete absence of Cockayne syndrome group B gene product gives rise to UV-sensitive syndrome but not Cockayne syndrome

DNA conformation-dependent activities of human mitochondrial RNA polymerase

DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics

DNA repair protein XPA binds replication protein A (RPA).

Diversity of Endonuclease V: From DNA Repair to RNA Editing

Effects of 5',8-cyclodeoxyadenosine triphosphates on DNA synthesis

Effects of DNA lesions on the transcription reaction of mitochondrial RNA polymerase: implications for bypass RNA synthesis on oxidative DNA lesions.

Effects of acetaldehyde-induced DNA lesions on DNA metabolism

Effects of endogenous DNA base lesions on transcription elongation by mammalian RNA polymerase II. Implications for transcription-coupled DNA repair and transcriptional mutagenesis.

Epigenetic modifications in DNA could mimic oxidative DNA damage: A double-edged sword.

Establishment of a human cell line stably overexpressing mouse Nip45 and characterization of Nip45 subcellular localization.

FEN1 participates in repair of the 5'-phosphotyrosyl terminus of DNA single-strand breaks

Facile preparation of a fluorescent probe to detect the cellular ability of nucleotide excision repair.

Fluorescence detection of DNA mismatch repair in human cells

Fluorescence detection of cellular nucleotide excision repair of damaged DNA.

Frequencies of mutagenic translesion DNA synthesis over cisplatin-guanine intra-strand crosslinks in lacZ plasmids propagated in human cells.

Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication.

Identification of Small Molecule Proliferating Cell Nuclear Antigen (PCNA) Inhibitor That Disrupts Interactions with PIP-box Proteins and Inhibits DNA Replication

Inhibition of nucleotide excision repair by anti-XPA monoclonal antibodies which interfere with binding to RPA, ERCC1, and TFIIH.

Inosine-specific ribonuclease activity of natural variants of human endonuclease V.

Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair

MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation

Miscoding properties of 8-chloro-2'-deoxyguanosine, a hypochlorous acid-induced DNA adduct, catalysed by human DNA polymerases

Molecular evidence of the involvement of the nucleotide excision repair (NER) system in the repair of the mono(ADP-ribosyl)ated DNA adduct produced by pierisin-1, an apoptosis-inducing protein from the cabbage butterfly.

Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex.

Nucleotide excision repair genes shaping embryonic development

Oligo swapping method for in vitro DNA repair substrate containing a single DNA lesion at a specific site

Oxygen free radical damage to DNA. Translesion synthesis by human DNA polymerase eta and resistance to exonuclease action at cyclopurine deoxynucleoside residues.

Polymerization by DNA polymerase eta is blocked by cis-diamminedichloroplatinum(II) 1,3-d(GpTpG) cross-link: implications for cytotoxic effects in nucleotide excision repair-negative tumor cells.

RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS.

Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease.

Repair synthesis step involving ERCC1-XPF participates in DNA repair of the Top1-DNA damage complex.

Resonance assignments, solution structure, and backbone dynamics of the DNA- and RPA-binding domain of human repair factor XPA.

Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA

The SLX4 complex is a SUMO E3 ligase that impacts on replication stress outcome and genome stability

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

Xeroderma pigmentosum group F protein binds to Eg5 and is required for proper mitosis: implications for XP-F and XFE.