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List of works by Hirofumi Noguchi

A Combined Continuous Density/Osmolality Gradient for Supplemental Purification of Human Islets.

scientific article published on January 2012

A Comparison of Proteins Expressed between Human and Mouse Adipose-Derived Mesenchymal Stem Cells by a Proteome Analysis through Liquid Chromatography with Tandem Mass Spectrometry ⬇️

scientific article

A Comparison of the Preservation of Mouse Adipose Tissue-Derived Mesenchymal Stem Cells Using the University of Wisconsin Solution and Hank's Balanced Salt Solution

scientific article published on 06 September 2018

A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Cells Cultured in DMEM 10% FBS and Chemically Defined Medium Using Human Adipose-Derived Mesenchymal Stem Cells

scientific article published on 13 July 2018

A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Primary Cultured Cells and Subcultured Cells Using Mouse Adipose-Derived Mesenchymal Stem Cells

scientific article published on 10 January 2019

A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of the Proteins Secreted by Human Adipose-Derived Mesenchymal Stem Cells

scientific article published on 18 September 2018

A case of thyroid cancer involving the trachea: treatment by partial tracheal resection and repair with a latissimus dorsi musculocutaneous flap

scientific article published on 01 May 2000

A culture substratum with net-like polyamide fibers promotes the differentiation of mouse and human pluripotent stem cells to insulin-producing cells

scientific article published on 19 June 2019

A human beta-cell line for transplantation therapy to control type 1 diabetes.

scientific article published on 25 September 2005

A new approach to develop a biohybrid artificial liver using a tightly regulated human hepatocyte cell line.

scientific article

A new mouse model for intraportal islet transplantation with limited hepatic lobe as a graft site

scientific article published on 01 September 2006

A newly developed bioartificial pancreas successfully controls blood glucose in totally pancreatectomized diabetic pigs.

scientific article published in July 2006

A novel gene expression system for detecting viable bladder cancer cells.

scientific article

A proteome analysis of pig pancreatic islets and exocrine tissue by liquid chromatography with tandem mass spectrometry

scientific article

A single transplantation of the islets can produce glycemic stability and reduction of basal insulin requirement

scientific article published on 05 April 2006

Activation of c-Jun NH2-terminal kinase (JNK) pathway during islet transplantation and prevention of islet graft loss by intraportal injection of JNK inhibitor

scientific article published on 16 January 2007

Activation of c-Jun NH2-terminal kinase during islet isolation.

scientific article published on 24 November 2006

Adhesion characteristics of porcine pancreatic islets and exocrine tissue to coating materials

scientific article published on 01 May 2018

Adipose tissue-derived mesenchymal stem cells ameliorate bone marrow aplasia related with graft-versus-host disease in experimental murine models

scientific article published on 01 April 2019

Adverse events in clinical islet transplantation: one institutional experience.

scientific article published in January 2012

Amelioration of diabetes in mice after single-donor islet transplantation using the controlled release of gelatinized FGF-2.

scientific article

Analysis of donor- and isolation-related variables from non-heart-beating donors (NHBDs) using the Kyoto islet isolation method

scientific article published on 01 January 2008

Assessment of Human Islet Isolation With Four Different Collagenases ⬇️

scientific article published on July 1, 2010

Assessment of islet quality following international shipping of more than 10,000 km.

scientific article published on 3 June 2010

Atorvastatin Inhibits the HIF1α-PPAR Axis, Which Is Essential for Maintaining the Function of Human Induced Pluripotent Stem Cells

scientific article published on 19 June 2018

BETA2/NeuroD protein can be transduced into cells due to an arginine- and lysine-rich sequence.

scientific article published in October 2005

BETA2/NeuroD protein transduction requires cell surface heparan sulfate proteoglycans.

scientific article published in January 2007

Basic and Clinical Science for Organ Biology

scientific article published on 12 December 2014

Body mass index reflects islet isolation outcome in islet autotransplantation for patients with chronic pancreatitis

scientific article published on 17 August 2010

Cancer stem cell-like characteristics of a CD133(+) subpopulation in the J82 human bladder cancer cell line

scientific article

Cell labeling with a novel contrast agent of magnetic resonance imaging.

scientific article published on 29 June 2010

Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function

scientific article published on 01 August 2005

Cell surface heparan sulfate proteoglycans mediate the internalization of PDX-1 protein.

scientific article published in January 2008

Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice

scientific article published on 07 February 2007

Characterization of human pancreatic progenitor cells.

scientific article published on 29 June 2010

Characterization of induced tissue-specific stem cells from pancreas by a synthetic self-replicative RNA

scientific article published in Scientific Reports

Choice of Feeders Is Important When First Establishing iPSCs Derived From Primarily Cultured Human Deciduous Tooth Dental Pulp Cells

scientific article published on 26 August 2015

Cluster analysis of self-monitoring blood glucose assessments in clinical islet cell transplantation for type 1 diabetes

scientific article

Comparison Between Modified Extracellular-Type Trehalose-Containing Kyoto Solution and University of Wisconsin Solution in 18-Hour Pancreas Preservation for Islet Transplantation

scientific article published on 01 August 2018

Comparison of Fresh and Cultured Islets From Human and Porcine Pancreata ⬇️

scientific article published on July 1, 2010

Comparison of M-Kyoto solution and histidine-tryptophan-ketoglutarate solution with a trypsin inhibitor for pancreas preservation in islet transplantation

scientific article published on 01 September 2007

Comparison of Modified Celsior Solution and M-Kyoto Solution for Pancreas Preservation in Human Islet Isolation ⬇️

scientific article published on January 1, 2010

Comparison of trypsin inhibitors in preservation solution for islet isolation.

scientific article published in January 2009

Comparison of ulinastatin, gabexate mesilate, and nafamostat mesilate in preservation solution for islet isolation.

scientific article published in January 2012

Construction and transplantation of an engineered hepatic tissue using a polyaminourethane-coated nonwoven polytetrafluoroethylene fabric.

scientific article published in January 2007

Construction of a differentiated human hepatocyte cell line expressing the herpes simplex virus-thymidine kinase gene.

scientific article

Controlled expansion of human endothelial cell populations by Cre-loxP-based reversible immortalization.

scientific article published on January 2002

Creating a Future of Transplantation

scientific article

Cryopreservation of human adipose tissue-derived stem/progenitor cells using the silk protein sericin.

scientific article published in January 2012

Cryopreservation of mouse adipose tissue-derived stem/progenitor cells.

scientific article

Development of Canine Models of Type 1 Diabetes With Partial Pancreatectomy and the Administration of Streptozotocin

scientific article published on 21 October 2013

Differential ability of somatic stem cells.

scientific article published in January 2009

Drug-Induced Naïve iPS Cells Exhibit Better Performance than Primed iPS Cells with Respect to the Ability to Differentiate into Pancreatic β-Cell Lineage

scientific article published on 02 September 2020

Ductal injection of JNK inhibitors before pancreas preservation prevents islet apoptosis and improves islet graft function

scientific article

Ductal injection of preservation solution increases islet yields in islet isolation and improves islet graft function.

scientific article published in January 2008

ER Stress and β-Cell Pathogenesis of Type 1 and Type 2 Diabetes and Islet Transplantation

scientific article published on 14 May 2013

ET-Kyoto ductal injection and density-adjusted purification combined with potent anti-inflammatory strategy facilitated single-donor islet transplantation: case reports.

scientific article published on July 2010

Efficient transfection of sendai virus vector to mouse pancreatic stem cells in the floating state.

scientific article published on 29 June 2010

Embryonic body formation using the tapered soft stencil for cluster culture device.

scientific article published on 26 February 2011

Enhanced Adipogenic Differentiation of Human Adipose-Derived Stem Cells in an In Vitro Microenvironment: The Preparation of Adipose-Like Microtissues Using a Three-Dimensional Culture.

scientific article published on 14 September 2016

Esophageal cancer associated with right aortic arch: report of two cases

scientific article published on 01 January 2003

Establishment of a reversibly immortalized human hepatocyte cell line by using Cre/loxP site-specific recombination.

scientific article published on August 2000

Establishment of an Immortalized Porcine Liver Cell Line JSNK-1 with Retroviral Transduction of SV40T ⬇️

scientific article published on January 1, 2010

Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT.

scientific article published on May 2004

Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers.

scientific article

Estimation of donor usability for islet isolation with the modified Ricordi method

scientific article published on 01 March 2008

Estimation of the distribution of intravenously injected adipose tissue-derived stem cells labeled with quantum dots in mice organs through the determination of their metallic components by ICPMS.

scientific article published on 13 October 2011

Evaluation of Osmolality of Density Gradient for Human Islet Purification ⬇️

scientific article published on January 1, 2012

Evaluation of endoscopic mucosal resection for superficial esophageal carcinoma

scientific article published on 01 December 2000

Evaluation of islet transplantation from non-heart beating donors

scientific article published on 01 August 2006

Evidence for Induced Expression of HLA Class II on Human Islets: Possible Mechanism for HLA Sensitization in Transplant Recipients.

scientific article published in February 2009

Excellence of Suito Index for Assessing Clinical Outcome of Islet Transplantation ⬇️

scientific article published on July 1, 2010

Excellent Islet Yields after 18-h Porcine Pancreas Preservation by Ductal Injection, Pancreas Preservation with MK Solution, Bottle Purification, and Islet Purification Using Iodixanol with UW Solution and Iodixanol with MK Solution

scientific article published on 30 September 2019

Exogenous DKK-3/REIC inhibits Wnt/β-catenin signaling and cell proliferation in human kidney cancer KPK1.

scientific article published on 28 August 2017

Facilitating Transplantation

scientific article published on 8 January 2017

False aneurysm of a hepatic artery branch complicating intrahepatic islet transplantation

scientific article published on 14 January 2009

Follow-up study of the first successful living donor islet transplantation.

scientific article published in December 2006

Free jejunal graft for hypopharyngeal and esophageal reconstruction

scientific article published on 9 July 2004

Fresh islets are more effective for islet transplantation than cultured islets.

scientific article

Gene expression profiling of human pancreatic islets undergoing a simulated process of instant blood-mediated inflammatory reaction

scientific article published in March 2008

Generation of Mouse STO Feeder Cell Lines That Confer Resistance to Several Types of Selective Drugs.

scientific article published on January 2012

Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors

scientific article

Identification of Proteins Differentially Expressed by Adipose-derived Mesenchymal Stem Cells Isolated from Immunodeficient Mice

scientific article published on 30 May 2019

Implication of pancreatic image findings in total pancreatectomy with islet autotransplantation for chronic pancreatitis.

scientific article published on January 2011

Improved Pancreatic Islet Isolation Outcome in Autologous Transplantation for Chronic Pancreatitis ⬇️

scientific article published on January 1, 2012

Improved method of human islet isolation for young donors.

scientific article published in July 2010

Improvement of pancreatic islet cell isolation for transplantation.

scientific article published on October 2007

Improvement of porcine islet isolation by inhibition of trypsin activity during pancreas preservation and digestion using α1-antitrypsin.

scientific article published in January 2012

Improving efficacy of clinical islet transplantation with iodixanol-based islet purification, thymoglobulin induction, and blockage of IL-1β and TNF-α

scientific article published on 08 March 2011

In vivo imaging of transplanted islets labeled with a novel cationic nanoparticle

scientific article

Induced Tissue-Specific Stem Cells and Epigenetic Memory in Induced Pluripotent Stem Cells.

scientific article

Induction of Expandable Adipose-Derived Mesenchymal Stem Cells from Aged Mesenchymal Stem Cells by a Synthetic Self-Replicating RNA ⬇️

scientific article published on 06 November 2018

Induction of insulin-producing cells from human pancreatic progenitor cells.

scientific article published on July 2010

Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology.

scientific article published on January 2006

Inflammatory pseudotumor of the spleen: a case report

scientific article published on 01 April 2000

Inhibition of inflammatory cytokine-induced response in human islet cells by withaferin A.

scientific article published on July 2010

Intrasplenic transplantation of immortalized human fetal hepatocytes prolongs the survival of 90% hepatectomized rats

scientific article published on 01 November 2000

In vitro generation of insulin-secreting cells from human pancreatic exocrine cells

scientific article published on August 2011

Iodixanol-controlled density gradient during islet purification improves recovery rate in human islet isolation.

scientific article published in June 2009

Islet cell transplantation for the treatment of type 1 diabetes in the USA.

scientific article

Islet purification method using large bottles effectively achieves high islet yield from pig pancreas

scientific article published in January 2012

Islet transplantation at the Diabetes Research Institute Japan.

scientific article published on 06 June 2008

Isolation and characterization of lymphoid enhancer factor-1-positive deciduous dental pulp stem-like cells after transfection with a piggyBac vector containing LEF1 promoter-driven selection markers.

scientific article published on 7 May 2017

Isolation and propagation of a human CD133(-) colon tumor-derived cell line with tumorigenic and angiogenic properties.

scientific article

Japanese Herbal Medicine TJ-48 Prevents Autoimmune Diabetes in NOD Mice ⬇️

scientific article published on January 1, 2011

Laparoscopy-assisted creation of a liver failure model in pigs.

scientific article published in January 2008

Large human islets secrete less insulin per islet equivalent than smaller islets in vitro ⬇️

scientific article published on January 1, 2011

Lentiviral transfer of the LacZ gene into human endothelial cells and human bone marrow mesenchymal stem cells

scientific article published on 01 January 2002

Lentiviral vector mediated gene delivery into non-dividing isolated islet cells

scientific article published on 01 February 2003

Living donor islet transplantation, the alternative approach to overcome the obstacles limiting transplant.

scientific article published in October 2006

Long-Expected New Start.

scientific article published on 14 May 2013

Maintenance of Viability and Function of Rat Islets With the Use of ROCK Inhibitor Y-27632.

scientific article published on 21 October 2013

Mechanism of PDX-1 protein transduction

scientific article published in 2005

Method for isolation of mouse pancreatic stem cells

scientific article

Modified cell-permeable JNK inhibitors efficiently prevents islet apoptosis and improves the outcome of islet transplantation

scientific article published on 23 July 2018

Modified two-layer preservation method (M-Kyoto/PFC) improves islet yields in islet isolation.

scientific article published in March 2006

Monitoring transplanted adipose tissue-derived stem cells combined with heparin in the liver by fluorescence imaging using quantum dots

scientific article published on 20 December 2011

Mutations in the C1 element of the insulin promoter lead to diabetic phenotypes in homozygous mice

scientific article published on 16 June 2020

Neovascularization induced around an artificial device implanted in the abdomen by the use of gelatinized fibroblast growth factor 2.

scientific article published in January 2009

Neurogenic differentiation 1 directs differentiation of cytokeratin 19-positive human pancreatic nonendocrine cells into insulin-producing cells.

scientific article

New stepwise cooling system for short-term porcine islet preservation

scientific article published on 01 October 2010

Novel Positive-Charged Nanoparticles for Efficient Magnetic Resonance Imaging of Islet Transplantation

scientific article published on January 2012

Novel cell-permeable p38-MAPK inhibitor efficiently prevents porcine islet apoptosis and improves islet graft function

scientific article published on 13 December 2019

Novel positively charged nanoparticle labeling for in vivo imaging of adipose tissue-derived stem cells

scientific article

Observation of Positively Charged Magnetic Nanoparticles Inside HepG2 Spheroids Using Electron Microscopy

scientific article published on 14 May 2013

One Hundred Human Pancreatic Islet Isolations at Baylor Research Institute ⬇️

scientific article published on October 1, 2010

Organ Biology-New Development

scientific article published on 21 October 2013

Organ/Cell Transplantation and Regenerative Medicine.

scientific article published on January 2012

PDX-1 protein containing its own antennapedia-like protein transduction domain can transduce pancreatic duct and islet cells

scientific article published in July 2003

PDX-1 protein is internalized by lipid raft-dependent macropinocytosis.

scientific article published in January 2005

Pancreas Procurement and Preservation for Islet Transplantation: Personal Considerations ⬇️

scientific article published on September 12, 2011

Pancreas preservation in extracellular-type p38 inhibitor-containing solution improves islet yield for porcine islet isolation

scientific article published on 24 November 2020

Pancreatic Islet Purification from Large Mammals and Humans Using a COBE 2991 Cell Processor versus Large Plastic Bottles

scientific article published on 23 December 2020

Pancreatic islet transplantation for treating diabetes

scientific article

Pancreatic islet transplantation.

scientific article

Pancreatic stem/progenitor cells for the treatment of diabetes.

scientific article

Photo-acceleration of protein release from endosome in the protein transduction system

scientific article published on 01 August 2004

Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy

scientific article published on 30 August 2012

Preservation of pancreas in the University of Wisconsin solution supplemented with AP39 reduces reactive oxygen species production and improves islet graft function

scientific article published on 19 November 2020

Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes.

scientific article

Procurement of the human pancreas for pancreatic islet transplantation from marginal cadaver donors.

scientific article published in August 2006

Production of pancreatic beta-cells from stem cells.

scientific article published on May 2010

Prolonged survival of mice with acute liver failure with transplantation of monkey hepatocytes cultured with an antiapoptotic pentapeptide V5.

scientific article published in February 2006

Protein transduction domains enable isolated islets to efficiently internalize the target protein.

scientific article published in February 2003

Protein transduction technology offers a novel therapeutic approach for diabetes.

scientific article published on January 2006

Protein transduction technology: a novel therapeutic perspective.

scientific article

Quantum dots for labeling adipose tissue-derived stem cells

scientific article published in January 2009

Quantum dots labeling using octa-arginine peptides for imaging of adipose tissue-derived stem cells

scientific article

Recent advances in stem cell research for the treatment of diabetes ⬇️

scientific article published on December 31, 2009

Recent progress in pancreatic islet transplantation

scientific article published on December 2011

Recombinant sendai virus-mediated gene transfer to mouse pancreatic stem cells.

scientific article published in January 2009

Reconstruction of pancreatic duct for previous Puestow operation for an islet autotransplantation

scientific article published on 01 August 2010

Reestablishment of microenvironment is necessary to maintain in vitro and in vivo human islet function.

scientific article published in January 2008

Regeneration of pancreatic islets in vivo by ultrasound-targeted gene therapy.

scientific article

Regulation of c-Jun NH2-Terminal Kinase for Islet Transplantation

scientific article published on 23 October 2019

Repeated human deciduous tooth-derived dental pulp cell reprogramming factor transfection yields multipotent intermediate cells with enhanced iPS cell formation capability

scientific article published in Scientific Reports

Retroperitoneal liposarcoma presenting a indirect inguinal hernia

scientific article published on 01 February 2001

Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes.

scientific article published on 5 November 2006

Reversible immortalization of adult human hepatocytes(1).

scientific article

Role of PDX-1 and MafA as a potential therapeutic target for diabetes.

scientific article published on 20 April 2007

Role of immortalized hepatocyte transplantation in acute liver failure.

scientific article published on February 2001

STO Feeder Cells Are Useful for Propagation of Primarily Cultured Human Deciduous Dental Pulp Cells by Eliminating Contaminating Bacteria and Promoting Cellular Outgrowth.

scientific article published on 25 October 2013

Secretory unit of islet in transplantation (SUIT) and engrafted islet rate (EIR) indexes are useful for evaluating single islet transplantation.

scientific article published in January 2008

Secretory unit of islet transplant objects (SUITO) index can predict outcome of intravenous glucose tolerance test.

scientific article published on July 2010

Secretory unit of islet transplant objects (SUITO) index can predict severity of hypoglycemic episodes in clinical islet cell transplantation

Simple evaluation of engraftment by secretory unit of islet transplant objects for living donor and cadaveric donor fresh or cultured islet transplantation.

scientific article

Spheroid Formation and Evaluation of Hepatic Cells in a Three-Dimensional Culture Device.

scientific article published on 26 August 2015

Stem cell applications in diabetes

scientific article published on January 2012

Stem cells for the treatment of diabetes.

scientific article published on 20 October 2006

Successful islet transplantation from nonheartbeating donor pancreata using modified Ricordi islet isolation method

scientific article published on 01 August 2006

Successful retroviral gene transfer of simian virus 40 T antigen and herpes simplex virus-thymidine kinase into human hepatocytes.

scientific article

Super-High-Dose Islet Transplantation Is Associated With High SUITO Index and Prolonged Insulin Independence: A Case Report ⬇️

scientific article published on July 1, 2010

Temporal decline in sirolimus elimination immediately after pancreatic islet transplantation

scientific article published on 01 December 2006

The Healing Effect of Human Milk Fat Globule-EGF Factor 8 Protein (MFG-E8) in A Rat Model of Parkinson's Disease

scientific article published on 31 August 2018

Three cases of adenocarcinoma arising in extremely long-segment Barrett's esophagus

scientific article published on 01 March 2006

Three-Dimensional In Vitro Hepatic Constructs Formed Using Combinatorial Tapered Stencil for Cluster Culture (TASCL) Device.

scientific article published on 12 December 2014

Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose.

scientific article

Transduction of cell-penetrating peptides into induced pluripotent stem cells.

scientific article published on 29 June 2010

Transplantation of osteogenically differentiated mouse iPS cells for bone repair.

scientific article published in January 2012

Treatment of acute liver failure in mice by hepatocyte xenotransplantation.

scientific article published on 23 June 2010

Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1.

scientific article

UW solution: a promising tool for cryopreservation of primarily isolated rat hepatocytes.

scientific article published in January 2002

Variables associated with islet yield in autologous islet cell transplantation for chronic pancreatitis

scientific article published on April 2010

[Islet transplantation]

scientific article published on 01 December 2011

piggyBac Transposon-Based Immortalization of Human Deciduous Tooth Dental Pulp Cells with Multipotency and Non-Tumorigenic Potential

scientific article published on 03 October 2019

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