Search filters

List of works by Martin Dyer

A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact.

scientific article published on 25 August 2014

A Double Hit CD10-Negative B-Cell Lymphoma with t(3;8)(q27;q24) Leading to Juxtaposition of the BCL6 and MYC Loci Associated with Good Clinical Outcome.

scientific article

A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation

scientific article published on 10 May 2007

A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia

scientific journal article

A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

scientific journal article

A high-density SNP genomewide linkage scan for chronic lymphocytic leukemia-susceptibility loci

scientific article published on 2 August 2005

A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma

scientific article published on 23 June 2017

A novel functional assay using etoposide plus nutlin-3a detects and distinguishes between ATM and TP53 mutations in CLL.

scientific article

A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells.

scientific article

A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies

scientific article published on 5 November 2015

A phase II multicenter study of the anti-CD19 antibody drug conjugate coltuximab ravtansine (SAR3419) in patients with relapsed or refractory diffuse large B-cell lymphoma previously treated with rituximab-based immunotherapy

scientific article published on 10 May 2018

A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment.

scientific article published on 02 June 2016

A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma.

scientific article published on 18 October 2013

A subset of Binet stage A CLL patients with TP53 abnormalities and mutated IGHV genes have stable disease

scientific article published on 25 September 2008

ABT-199 selectively inhibits BCL2 but not BCL2L1 and efficiently induces apoptosis of chronic lymphocytic leukaemic cells but not platelets.

scientific article

ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele ⬇️

scientific article published on September 20, 2011

Activity of thalidomide and lenalidomide in mantle cell lymphoma.

scientific article

Alemtuzumab-resistant Sézary syndrome responding to zanolimumab

scientific article published on 12 April 2011

Antibody therapy of malignancy

scientific article published on 01 January 1992

Apoptosis induced by histone deacetylase inhibitors in leukemic cells is mediated by Bim and Noxa.

scientific article published on 24 May 2007

B cell prolymphocytic leukaemia (B-PLL) with complex karyotype and concurrent abnormalities of the p53 and c-MYC gene

scientific article published on 01 June 1999

BCL7A protein expression in normal and malignant lymphoid tissues.

scientific article published on 9 October 2012

Barriers to effective TRAIL-targeted therapy of malignancy

scientific article published on 01 October 2007

Biallelic ATM inactivation significantly reduces survival in patients treated on the United Kingdom Leukemia Research Fund Chronic Lymphocytic Leukemia 4 trial

scientific article published on 22 October 2012

Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33).

scientific article

Bilateral subdural hygromas following intrathecal methotrexate

scientific article published on 19 September 2011

Bioweapons of tumor mass destruction?

scientific article published on 01 July 2003

Bisindolylmaleimide IX is a potent inducer of apoptosis in chronic lymphocytic leukaemic cells and activates cleavage of Mcl-1.

scientific article published in October 2003

Breaking good: the inexorable rise of BTK inhibitors in the treatment of chronic lymphocytic leukaemia.

scientific article published on 18 April 2014

CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B

scientific article

CDDO induces apoptosis via the intrinsic pathway in lymphoid cells.

scientific article published in May 2004

CUDC-907 blocks multiple pro-survival signals and abrogates microenvironment protection in CLL

scientific article published on 24 October 2018

CXCL-8/IL8 Produced by Diffuse Large B-cell Lymphomas Recruits Neutrophils Expressing a Proliferation-Inducing Ligand APRIL.

scientific article published on 6 December 2016

Caspase cleavage of Itch in chronic lymphocytic leukemia cells.

scientific article

Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia.

scientific article published on 24 January 2014

Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.

scientific article

Cloning of immunoglobulin chromosomal translocations by long-distance inverse polymerase chain reaction.

scientific article

Clustering of missense mutations in the ataxia-telanglectasia gene in a sporadic T-cell leukaemia ⬇️

scientific article published on September 1, 1997

Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk

scientific article published on 10 January 2010

Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk.

scientific article published on 3 November 2014

Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia

scientific article

Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes.

scientific article published on 30 June 2004

Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.

scientific article published in May 2003

Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies

article

DNA methylation profiling identifies candidate genes for the pathogenesis of hepatosplenic T-cell lymphoma

article

David Galton--the thesis years

scientific article published on 01 December 2007

Defining the prognosis of early stage chronic lymphocytic leukaemia patients

scientific article published on 15 December 2011

Delta N-p73: the enemy within

scientific article published on 01 December 2005

Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia

scientific article published on 29 July 2009

Detection of chromothripsis-like patterns with a custom array platform for chronic lymphocytic leukemia.

scientific article published on 25 August 2015

Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization

scientific article published on 01 September 2001

Different forms of cell death induced by putative BCL2 inhibitors.

scientific article

Differential activation of pro-survival pathways in response to CD40LG/IL4 stimulation in chronic lymphocytic leukaemia cells

scientific article published on 20 April 2018

Dopamine targets cycling B cells independent of receptors/transporter for oxidative attack: Implications for non-Hodgkin's lymphoma.

scholarly article

Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells

scientific article published on 31 January 2008

Drug cross-resistance and therapy-induced resistance in chronic lymphocytic leukaemia by an enhanced method of individualised tumour response testing

scientific article

Dual dependence on BCL2 and MCL1 in T-cell prolymphocytic leukemia

scientific article published on 01 February 2020

Efficacy of vemurafenib in hairy-cell leukemia.

scientific article

Efficacy of venetoclax monotherapy in patients with relapsed, refractory mantle cell lymphoma after Bruton tyrosine kinase inhibitor therapy

scientific article published on 06 September 2018

Enforced expression of MIR142, a target of chromosome translocation in human B-cell tumors, results in B-cell depletion

scientific article published on 25 October 2017

Enhanced Fas-associated death domain recruitment by histone deacetylase inhibitors is critical for the sensitization of chronic lymphocytic leukemia cells to TRAIL-induced apoptosis.

scientific article published on 3 November 2009

Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells.

scientific article

Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia.

scientific article published on 27 May 2013

Enhancing the anti-lymphoma potential of 3,4-methylenedioxymethamphetamine (‘ecstasy’) through iterative chemical redesign: mechanisms and pathways to cell death ⬇️

scientific article published on August 18, 2011

Eosinophilic cellulitis as a presenting feature of chronic eosinophilic leukaemia, secondary to a deletion on chromosome 4q12 creating the FIP1L1-PDGFRA fusion gene.

scientific article

Eμ/miR-125b transgenic mice develop lethal B-cell malignancies.

scientific article published on 8 July 2011

Fine-scale mapping of the 6p25.3 chronic lymphocytic leukaemia susceptibility locus.

scientific article published in February 2010

Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).

scientific article

Gains of the proto-oncogene BCL11A and nuclear accumulation of BCL11A(XL) protein are frequent in primary mediastinal B-cell lymphoma.

scientific article

Gains ofREL in primary mediastinal B-cell lymphoma coincide with nuclear accumulation of REL protein

scientific article published on 01 April 2007

Genes encoding members of the JAK-STAT pathway or epigenetic regulators are recurrently mutated in T-cell prolymphocytic leukaemia.

scientific article

Genetic variation in CXCR4 and risk of chronic lymphocytic leukemia

scientific article

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

scientific article published on 06 February 2017

Genomic abnormalities acquired in the blastic transformation of splenic marginal zone B-cell lymphoma.

scientific article published on March 2003

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia.

scientific article published on 10 June 2016

Germline mutations in shelterin complex genes are associated with familial chronic lymphocytic leukemia

scientific article

Guidelines on the investigation and management of follicular lymphoma

scientific article published on 23 December 2011

HHV-8-unrelated primary effusion-like lymphoma associated with clonal loss of inherited chromosomally-integrated human herpesvirus-6A from the telomere of chromosome 19q.

scientific article published on 7 March 2016

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

scientific article

High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma.

scientific article

Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies.

scientific article

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

scientific article

Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays

scientific article published on 01 June 2005

Hsp72 and Nek6 Cooperate to Cluster Amplified Centrosomes in Cancer Cells ⬇️

scientific article published on 18 July 2017

Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome

scientific article published on 19 September 2013

Humanized CD52 monoclonal antibody campath-1H as first-line treatment in chronic lymphocytic leukaemia

scientific article published on 01 April 1996

Humanized anti-CD20 antibody, veltuzumab, in refractory/recurrent non-Hodgkin's lymphoma: phase I/II results.

scientific article

Ibrutinib efficacy and tolerability in patients with relapsed chronic lymphocytic leukemia following allogeneic HCT.

scientific article

Identification of Thr29 as a critical phosphorylation site that activates the human proton channel Hvcn1 in leukocytes

scientific article

IgD class switching: identification of a novel recombination site in neoplastic and normal B cells.

scientific article published in December 1995

Immunoblastic transformation of a Sezary syndrome in a black Caribbean patient without evidence of HTLV-I.

scientific article published in August 1995

Improved classification of leukemic B-cell lymphoproliferative disorders using a transcriptional and genetic classifier.

scientific article

Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity

scientific article

Inhibition of Histone Deacetylase Class I but not Class II Is Critical for the Sensitization of Leukemic Cells to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis

article by Satoshi Inoue et al published 1 July 2006 in Cancer Research

Inhibition of bortezomib-induced apoptosis by red blood cell uptake.

scientific article published on 22 June 2006

Insight into the pathogenesis of chronic lymphocytic leukemia (CLL) through analysis of IgVH gene usage and mutation status in familial CLL

article

Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci

scientific article published on 01 March 2002

Interphase cytogenetic characterization of aberrations in the long arm of chromosome 1 in B-cell lymphoid malignancies

scientific article published on 01 July 2003

Kinetics of T-cell subset reconstitution following treatment with bendamustine and rituximab for low-grade lymphoproliferative disease: a population-based analysis

scientific article published on 13 December 2018

Lack of MDM2 amplification in human leukaemia

scientific article published on 01 February 1994

Laparoscopic splenectomy: a personal series of 140 consecutive cases

scientific article

Levels of expression of CD52 in normal and leukemic B and T cells: correlation with in vivo therapeutic responses to Campath-1H

scientific article published on 01 February 1998

Long-term follow-up of patients with CLL treated with the selective Bruton's tyrosine kinase inhibitor ONO/GS-4059.

scientific article published on 4 April 2017

Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma

scientific article published on 01 December 2001

MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.

scientific article

Male preponderance in chronic lymphocytic leukemia utilizing IGHV 1-69

scientific article published on 28 June 2007

Management guidelines for use of alemtuzumab in B-cell chronic lymphocytic leukemia

scientific article published on March 2004

Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.

scientific article published in October 2002

Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy

scientific article

Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion.

scientific article published on 29 October 2007

New Agents to Treat Chronic Lymphocytic Leukemia.

scientific article published in June 2016

No cardiac toxicity associated with alemtuzumab therapy for mycosis fungoides/Sézary syndrome

scientific article published on 01 May 2005

Novel markers of normal and neoplastic human plasmacytoid dendritic cells

scientific article published on 24 January 2008

Obinutuzumab-induced coagulopathy in chronic lymphocytic leukaemia with trisomy 12.

scientific article published on 17 June 2016

Ofatumumab monotherapy in relapsed/refractory mantle cell lymphoma--a phase II trial

scientific article published on 08 February 2014

Ofatumumab retreatment and maintenance in fludarabine-refractory chronic lymphocytic leukaemia patients

scientific article published on 30 March 2015

PML/RAR alpha + ATRA = CR. A comment on acute promyelocytic leukaemia: molecular pathology and treatment

scientific article published on 01 January 1994

Paradoxical activation of alternative pro-survival pathways determines resistance to MEK inhibitors in chronic lymphocytic leukaemia

scientific article

Peripheral T-cell non-Hodgkin's lymphoma NOS: naming of parts

scientific article published on 01 February 2006

Phase 1b Study of Tirabrutinib in Combination With Idelalisib or Entospletinib in Previously Treated Chronic Lymphocytic Leukemia

scientific article published on 10 March 2020

Phase 1b study of venetoclax-obinutuzumab in previously untreated and relapsed/refractory chronic lymphocytic leukemia

scientific article published on 12 March 2019

Phase IA/II, multicentre, open-label study of the CD40 antagonistic monoclonal antibody lucatumumab in adult patients with advanced non-Hodgkin or Hodgkin lymphoma.

scientific article

Pituitary infiltration in B-cell chronic lymphocytic leukaemia

scientific article published on 01 December 2001

Positron emission tomography features of hidradenitis suppurativa.

scientific article published on August 2011

Posttranscriptional Upregulation of p53 by Reactive Oxygen Species in Chronic Lymphocytic Leukemia.

scientific article

Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol

scientific article published on 08 April 2010

Primary lymphoma-like lesions of the uterine cervix; sheep in wolves' clothing

scientific article published on 16 March 2011

Pro-survival signal inhibition by CDK inhibitor dinaciclib in Chronic Lymphocytic Leukaemia

scientific article published on 29 July 2016

Protein profiling of plasma membranes defines aberrant signaling pathways in mantle cell lymphoma.

scientific article published on 2 April 2009

Proteomic analysis of cell surface membrane proteins in leukemic cells

scientific article published on 01 January 2007

Pyoderma gangrenosum complicating pegylated granulocyte colony-stimulating factor in Hodgkin lymphoma

scientific article published on 01 January 2006

REMISSION INDUCTION IN NON-HODGKIN LYMPHOMA WITH RESHAPED HUMAN MONOCLONAL ANTIBODY CAMPATH-1H

scientific article published in The Lancet

Rapid amplification of immunoglobulin heavy chain switch (IGHS) translocation breakpoints using long-distance inverse PCR

scientific article published on 01 December 2004

Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma.

scientific article

Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia

scientific article published on 21 January 2014

Recurrent mutations of the exportin 1 gene (XPO1) and their impact on selective inhibitor of nuclear export compounds sensitivity in primary mediastinal B-cell lymphoma

scientific article published on 16 June 2016

Remission Induction in Patients with Lymphoid Malignancies Using Unconjugated CAMPATH-1 Monoclonal Antibodies.

scientific article published on January 1990

Report: workshop on mediastinal grey zone lymphoma

article by Sibrand Poppema et al published 6 June 2005 in European Journal of Haematology

Responses to the Selective Bruton's Tyrosine Kinase (BTK) Inhibitor Tirabrutinib (ONO/GS-4059) in Diffuse Large B-cell Lymphoma Cell Lines.

scientific article published on 23 April 2018

S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.

scientific article published on 13 April 2018

SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia.

scientific article published in May 2018

Safety and efficacy of abexinostat, a pan-histone deacetylase inhibitor, in non-Hodgkin lymphoma and chronic lymphocytic leukemia: results of a phase II study

scientific article

Safety and efficacy of obinutuzumab with CHOP or bendamustine in previously untreated follicular lymphoma.

scientific article

Splenic infarction associated with rapidly progressive chronic lymphocytic leukemia with complex karyotype and ATM mutation

scientific article published on 24 December 2010

Subcutaneous CAMPATH-1H in fludarabine-resistant/relapsed chronic lymphocytic and B-prolymphocytic leukaemia

scientific article published on 01 March 1997

T-Cell Receptor and Immunoglobulin Gene Rearrangements in Acute Myeloid and Undifferentiated Leukemias of Adults: Correlation with Weak Surface Expression of CD45 and CDw52 Antigens.

scientific article published in January 1991

T-cell prolymphocytic leukaemia: antigen receptor gene rearrangement and a novel mode of MTCP1 B1 activation

scientific article published on 01 September 2000

TP53 codon 72 polymorphism in patients with chronic lymphocytic leukaemia: identification of a subgroup with mutated IGHV genes and poor clinical outcome

scientific article published on 17 February 2011

TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies

scientific article published on 01 December 2005

TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2.

scientific article

Targeting anti-apoptotic BCL2 family proteins in haematological malignancies - from pathogenesis to treatment.

scientific article

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

scientific article published on 13 April 2009

Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in hematologic malignancies

scientific article published on 22 November 2018

The B-cell lymphoma 2 (BCL2)-inhibitors, ABT-737 and ABT-263, are substrates for P-glycoprotein.

scientific article published on 13 April 2011

The BCL11 gene family: involvement of BCL11A in lymphoid malignancies ⬇️

scientific article published on December 1, 2001

The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells

scientific article published on 18 May 2006

The BCL7 gene family: deletion of BCL7B in Williams syndrome.

scientific article published on December 1998

The CAMPATH-1 antigen (CDw52)

scientific article published on 01 March 1990

The Detection of Chromosomal Translocations Involving the Immunoglobulin Loci in B-Cell Malignancies ⬇️

scientific article published on 01 January 2013

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.

scientific article

The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function

scientific article published on 6 December 2017

The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma ⬇️

scientific article published on September 6, 2012

The evolving role of alemtuzumab in management of patients with CLL.

scientific article

The improved lytic function andin vivo efficacy of monovalent monoclonal CD3 antibodies

scientific article published on 01 February 1989

The pathogenetic role of oncogenes deregulated by chromosomal translocation in B-cell malignancies.

scientific article

Transcriptional silencing of Polo-like kinase 2 (SNK/PLK2) is a frequent event in B-cell malignancies.

scientific article published on 13 September 2005

Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations

scientific article published on 24 October 2002

Trisomy 19 is associated with trisomy 12 and mutatedIGHVgenes in B-chronic lymphocytic leukaemia

scientific article published on 01 July 2007

Unusual deletions in the immunoglobulin heavy chain locus in follicular B-cell lymphoma with t(14;18)(q32.3;q21.3)

scientific article published on 01 December 1993

Upregulation of TRAIL-R2 is not involved in HDACi mediated sensitization to TRAIL-induced apoptosis

scientific article published on 26 May 2006

p73, miR106b, miR34a, and Itch in chronic lymphocytic leukemia

scientific article published on 01 June 2009

pH regulation and beyond: unanticipated functions for the voltage-gated proton channel, HVCN1 ⬇️

scientific article published on October 18, 2010

t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).

scientific article

t(X;14)(p11;q32) in MALT lymphoma involving GPR34 reveals a role for GPR34 in tumor cell growth.

scientific article

Paulina is supported by:

About Paulina

Help