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List of works by Patrick Matthys

A Murine Intestinal Intraepithelial NKp46-Negative Innate Lymphoid Cell Population Characterized by Group 1 Properties.

scientific article published on May 2017

A novel kindred with inherited STAT2 deficiency and severe viral illness

scientific article published on 5 January 2017

A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner.

scientific article published in August 2007

A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate

scientific article published on 01 December 2020

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

scientific article published on 14 August 2011

A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis

scholarly article by D. Elewaut et al published 22 February 2011 in Annals of the Rheumatic Diseases

AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-gamma receptor-deficient mice.

scientific article

Abnormal differentiation of B cells and megakaryocytes in Roifman syndrome.

scientific article published on 29 January 2018

Activated CD4+CD25+ regulatory T cells inhibit osteoclastogenesis and collagen-induced arthritis

scientific article published on 14 May 2008

Advances in the pathogenesis of primary and secondary haemophagocytic lymphohistiocytosis: differences and similarities

scientific article published on 5 June 2016

Airway IgG counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on Fc gamma R and IFN-gamma.

scientific article published in August 2003

An Acute Abdomen Mimicking Appendicitis

scientific article published on 29 January 2016

Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-γ receptor-deficient mice ⬇️

scientific article published on July 1, 1998

Anti-interferon-γ antibody treatment, growth of Lewis lung tumours in mice and tumour-associated cachexia

scientific article published on 01 January 1991

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells

scientific article

CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines

scientific article published in April 2008

Cidofovir treatment improves the pathology caused by the growth of human papillomavirus-positive cervical carcinoma xenografts in athymic nude mice

scientific article

Collagen-Induced Arthritis as an Animal Model for Rheumatoid Arthritis: Focus on Interferon-γ ⬇️

scientific article published on 09 September 2011

Collagen-induced arthritis and related animal models: how much of their pathogenesis is auto-immune, how much is auto-inflammatory?

scientific article published on October 2011

Cytokine balance and cytokine-driven natural killer cell dysfunction in systemic juvenile idiopathic arthritis.

scientific article

Cytokines and cachexia ⬇️

scientific article published on September 1, 1997

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

scientific article published on 12 March 2015

Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma

scientific article

Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-gamma and counteraction by interferon-gamma.

scientific article published on 17 August 2009

Effects of anti-interferon-gamma and anti-interleukin-6 antibodies in disease models in mice: antibodies as carriers of cytokines

scientific article published on 01 October 1994

Emergence of cowpox: study of the virulence of clinical strains and evaluation of antivirals

scientific article

Excavated mass and double tracking in the sigmoid colon due to colocolic fistula complicating diverticulitis ⬇️

scientific article published on 01 September 2012

Focal infarction of lesser omentum ⬇️

scientific article published on 01 November 2011

Foxp3+CD25+ T regulatory cells stimulate IFN-gamma-independent CD152-mediated activation of tryptophan catabolism that provides dendritic cells with immune regulatory activity in mice unresponsive to staphylococcal enterotoxin B

scientific article published on 01 July 2007

Freund's complete adjuvant induces arthritis in mice lacking a functional interferon-gamma receptor by triggering tumor necrosis factor alpha-driven osteoclastogenesis

scientific article

Gene Expression Profiling Reveals Clear Differences Between EBV-Positive and EBV-Negative Posttransplant Lymphoproliferative Disorders

article

Hantavirus infection in Brazilian patients from Recife with suspected leptospirosis

scientific article published in The Lancet

Hemophagocytic lymphohistiocytosis (HLH): A heterogeneous spectrum of cytokine-driven immune disorders.

scientific article

How Viruses Contribute to the Pathogenesis of Hemophagocytic Lymphohistiocytosis

scientific article published on 7 September 2017

How interferon-gamma keeps autoimmune diseases in check.

scientific article published on 03 September 2008

IDO1 Deficiency Does Not Affect Disease in Mouse Models of Systemic Juvenile Idiopathic Arthritis and Secondary Hemophagocytic Lymphohistiocytosis.

scientific article

IFN-γ stimulates CpG-induced IL-10 production in B cells via p38 and JNK signalling pathways

scientific article published on 01 August 2018

IL-10- and IL-12-independent down-regulation of allergic sensitization by stimulation of CD40 signaling

scientific article published on 01 October 2006

IL-12 contributes to allergen-induced airway inflammation in experimental asthma

scientific article published on 01 November 2006

IL-2 consumption by highly activated CD8 T cells induces regulatory T-cell dysfunction in patients with hemophagocytic lymphohistiocytosis

scientific article

Immunomodulatory properties of interferon-gamma. An update

scientific article published on 01 September 1998

Increased mortality and impaired clonal deletion after staphylococcal enterotoxin B injection in old mice: relation to cytokines and nitric oxide production.

scientific article

Inducible nitric oxide synthase in the anterior pituitary gland: induction by interferon-gamma in a subpopulation of folliculostellate cells and in an unidentifiable population of non-hormone-secreting cells.

scientific article published on June 1997

Induction of IL-15 by TCR/CD3 aggregation depends on IFN-gamma and protects against apoptosis of immature thymocytes in vivo

scientific article published on 01 December 2002

Inflammatory Gene Expression Profile and Defective Interferon-γ and Granzyme K in Natural Killer Cells From Systemic Juvenile Idiopathic Arthritis Patients

scientific article published on October 2016

Inhibiting cytokines of the interleukin-12 family: recent advances and novel challenges.

scientific article published on February 2004

Insufficient IL-10 Production as a Mechanism Underlying the Pathogenesis of Systemic Juvenile Idiopathic Arthritis

scientific article published on 28 September 2018

Interferon-gamma, more of a cachectin than tumor necrosis factor

scientific article published on July 1, 1992

Involvement of nitric oxide in the interferon-gamma-induced inhibition of growth hormone and prolactin secretion in anterior pituitary cell cultures.

scientific article published on May 1997

Limitations of neutrophil depletion by anti-Ly6G antibodies in two heterogenic immunological models

scientific article published on 18 June 2019

Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator.

scientific article published on 10 September 2008

Lymphocyte-independent pathways underlie the pathogenesis of murine cytomegalovirus-associated secondary hemophagocytic lymphohistiocytosis.

scientific article published on 27 November 2017

Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis

scientific article published on 19 December 2017

Mac-1(+) myelopoiesis induced by CFA: a clue to the paradoxical effects of IFN-gamma in autoimmune disease models.

scientific article

Macrophage activation syndrome: characteristic findings on liver biopsy illustrating the key role of activated, IFN-gamma-producing lymphocytes and IL-6- and TNF-alpha-producing macrophages

scientific article published on 05 October 2004

Macrophages have no lineage history of Foxp3 expression.

scientific article published in February 2012

Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases

scientific article published in July 2012

Modification of the anti-CD3-induced cytokine release syndrome by anti-interferon-gamma or anti-interleukin-6 antibody treatment: protective effects and biphasic changes in blood cytokine levels

scientific article published on 01 September 1993

Molecular imaging of rheumatoid arthritis: emerging markers, tools, and techniques

scientific article

Molecular imaging with macrophage CRIg-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis.

scientific article published on 31 March 2014

Mouse Cytomegalovirus Infection in BALB/c Mice Resembles Virus-Associated Secondary Hemophagocytic Lymphohistiocytosis and Shows a Pathogenesis Distinct from Primary Hemophagocytic Lymphohistiocytosis

scientific article

Mycophenolate mofetil inhibits the development of Coxsackie B3-virus-induced myocarditis in mice

scientific article

Natural Killer Cells in Systemic Autoinflammatory Diseases: A Focus on Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome

scientific article published on 01 January 2019

Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis

scientific article

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part one

article

Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

scientific article

Protective role of IFN-gamma in collagen-induced arthritis conferred by inhibition of mycobacteria-induced granulocyte chemotactic protein-2 production.

scientific article published on 2 January 2007

Pseudo-achalasia: a complication of laparoscopic adjustable gastric banding

scientific article published on 01 July 2014

Pulmonary inflammation in mice with collagen-induced arthritis is conditioned by complete Freund's adjuvant and regulated by endogenous IFN-γ

scientific article published on 16 October 2012

Recovery of humoral immunity is critical for successful antiviral therapy in disseminated mouse adenovirus type 1 infection

scientific article published on 11 February 2008

Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir

scientific article

Regulatory Role for NK Cells in a Mouse Model of Systemic Juvenile Idiopathic Arthritis

scientific article published on 01 November 2019

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

scientific article

Reversible splenic ischemia in inflammatory bowel disease

scientific article published on 01 July 2011

Role of interferon-gamma and nitric oxide in pulmonary edema and death induced by lipopolysaccharide

scientific article published on 01 January 2000

SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis

scientific article published on 27 February 2013

Severe cachexia in mice inoculated with interferon-gamma-producing tumor cells

scientific article published on 01 August 1991

Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

scientific article published on 25 October 2016

Spinal abnormalities in vitamin B12 deficiency ⬇️

scientific article published on 01 March 2011

Study of camelpox virus pathogenesis in athymic nude mice

scientific article (publication date: 2011)

Symptomatic human hantavirus in the Americas.

scientific article published in February 2007

Systemic juvenile idiopathic arthritis-like syndrome in mice following stimulation of the immune system with Freund's complete adjuvant: regulation by interferon-γ

scientific article published on 01 May 2014

TH1 and TH17 cells promote crescent formation in experimental autoimmune glomerulonephritis

scientific article published on 11 June 2015

The Ly49E Receptor Inhibits the Immune Control of Acute Trypanosoma cruzi Infection.

scientific article

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

scientific article published on 18 December 2011

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

scientific article published on 29 April 2020

Therapeutic Potential of Interferon-γ and Its Antagonists in Autoinflammation: Lessons from Murine Models of Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome

scientific article

Traumatic urinary bladder rupture: the usefulness of CT cystography

scientific article published on 01 March 2013

Understanding the dosimetric powder EPR spectrum of sucrose by identification of the stable radiation-induced radicals.

scientific article

Understanding the spectrum of haemophagocytic lymphohistiocytosis: update on diagnostic challenges and therapeutic options.

scientific article

Unexpected pyomyositis of right buttock ⬇️

scientific article published on 01 November 2011

[The effect of interferon-gamma in collagen-induced arthritis in mice shows a mechanism of expanding Mac-1+ blood cells during its pathogenesis]

scientific article published on 01 January 2005

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