List of works - Steve Schoonooghe

A new model for intermediate molecular weight recombinant bispecific and trispecific antibodies by efficient heterodimerization of single chain variable domains through fusion to a Fab-chain

scientific article published in June 2001

Biodistribution and planar gamma camera imaging of (123)I- and (131)I-labeled F(ab')(2) and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor.

scientific article published on April 2007

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

scientific article published on 27 January 2016

CD3 x CD28 cross-interacting bispecific antibodies improve tumor cell dependent T-cell activation.

scientific article

Development and Characterization of Nanobodies Targeting the Kupffer Cell

scientific article published on 22 February 2021

Development of VEGFR2-specific Nanobody Pseudomonas exotoxin A conjugated to provide efficient inhibition of tumor cell growth

scientific article published on 29 September 2012

Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris

scientific article published on 11 August 2009

Engineering and Expression of Bibody and Tribody Constructs in Mammalian Cells and in the Yeast Pichia pastoris ⬇️

scientific article published on 01 January 2012

Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent

scientific article published on 21 June 2019

Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives.

scientific article

Generation and characterization of a functional Nanobody against the vascular endothelial growth factor receptor-2; angiogenesis cell receptor

scientific article

Generation and in vivo characterization of a chimeric αvβ5-targeting antibody 14C5 and its derivatives.

scientific article

In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model.

scientific article

Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis.

scientific article published on 23 June 2016

Molecular imaging with macrophage CRIg-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis.

scientific article published on 31 March 2014

Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

scientific article published on 02 October 2014

Monoclonal antibody 14C5 targets integrin alphavbeta5.

scientific article

NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis

scientific article published on 08 July 2019

Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages.

scientific article

New strategies in polypeptide and antibody synthesis: an overview

scientific article published on February 2004

Novel applications of nanobodies for in vivo bio-imaging of inflamed tissues in inflammatory diseases and cancer.

scientific article published on 21 July 2012

Novel half-life extended anti-MIF nanobodies protect against endotoxic shock.

scientific article published on 25 January 2018

Optimizing expression and purification from cell culture medium of trispecific recombinant antibody derivatives.

scientific article published on March 2003

PET Imaging of Macrophage Mannose Receptor-Expressing Macrophages in Tumor Stroma Using 18F-Radiolabeled Camelid Single-Domain Antibody Fragments

scientific article published on 11 June 2015

PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1.

scientific article published on 8 July 2010

Production of antibody derivatives in the methylotrophic yeast Pichia pastoris

scientific article published on 01 January 2012

SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis

scientific article published on 27 February 2013

Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages

scientific article published on 21 February 2019

Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

scientific article published on 25 October 2016

Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity

scientific article published on 18 November 2016

List of works by Steve Schoonooghe

A new model for intermediate molecular weight recombinant bispecific and trispecific antibodies by efficient heterodimerization of single chain variable domains through fusion to a Fab-chain

Biodistribution and planar gamma camera imaging of (123)I- and (131)I-labeled F(ab')(2) and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor.

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

CD3 x CD28 cross-interacting bispecific antibodies improve tumor cell dependent T-cell activation.

Development and Characterization of Nanobodies Targeting the Kupffer Cell

Development of VEGFR2-specific Nanobody Pseudomonas exotoxin A conjugated to provide efficient inhibition of tumor cell growth

Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris

Engineering and Expression of Bibody and Tribody Constructs in Mammalian Cells and in the Yeast Pichia pastoris ⬇️

Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent

Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives.

Generation and characterization of a functional Nanobody against the vascular endothelial growth factor receptor-2; angiogenesis cell receptor

Generation and in vivo characterization of a chimeric αvβ5-targeting antibody 14C5 and its derivatives.

In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model.

Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis.

Molecular imaging with macrophage CRIg-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis.

Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

Monoclonal antibody 14C5 targets integrin alphavbeta5.

NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis

Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages.

New strategies in polypeptide and antibody synthesis: an overview

Novel applications of nanobodies for in vivo bio-imaging of inflamed tissues in inflammatory diseases and cancer.

Novel half-life extended anti-MIF nanobodies protect against endotoxic shock.

Optimizing expression and purification from cell culture medium of trispecific recombinant antibody derivatives.

PET Imaging of Macrophage Mannose Receptor-Expressing Macrophages in Tumor Stroma Using 18F-Radiolabeled Camelid Single-Domain Antibody Fragments

PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1.

Production of antibody derivatives in the methylotrophic yeast Pichia pastoris

SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis

Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages

Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity